Matches 1 - 43 out of 43
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7381315 Multi-channel analyte-separation device employing side-entry excitation  
A side-entry excitation arrangement is provided with a multi-channel analyte-separation device. In various embodiments, a plurality of channels are disposed in an array, with a laser disposed to...
7361259 Capillary array and electrophoresis apparatus, and method  
A capillary electrophoresis device including a capillary array, and a method of manufacturing the capillary array, are provided. During the manufacture of the capillary array, a plurality of...
7335470 Compilations of nucleic acids and arrays and methods of using them  
In one aspect the invention provides compilations of nucleic acids, articles of manufacture, e.g., arrays, and methods for the detection of chromosomal abnormalities, such as a chromosomal...
7309409 Multi-channel bio-separation cartridge  
A bio-separation system using an efficient, compact, portable, interchangeable, reusable, recyclable, multi-channel cartridge, has integrated pre-aligned optics and an integrated reagent reservoir....
7280207 Time-delay integration in a flow cytometry system  
An apparatus for detecting analytes in a sample is provided. The apparatus can include: a flow cytometry system including one or more detection zones; one or more irradiation sources disposed for...
7265833 Electrophoretic system with multi-notch filter and laser excitation source  
Apparatus and methods for detecting analytes in a sample are provided. The apparatus can include: one or more channels having a detection zone; one or more irradiation sources disposed for...
7250098 Multi-capillary array electrophoresis device  
An electrophoresis apparatus includes a multi-capillary array having a liquid or solid disposed between the capillaries of the array. The liquid or solid exhibits a refractive index higher than...
7223326 Capillary electrophoresis system  
A capillary electrophoresis system includes a plurality of capillaries arranged in parallel on a vertical plane at an identical distance from each other, each of which has a sample injection end...
7208072 Multi-segment cartridge for bio-separation with multiplexed fluorescence detection  
A bio-separation instrument using a multi-segment cartridge. The cartridge includes a plurality of efficient, compact, portable, interchangeable, reusable, recyclable, modular, multi-channel...
7189361 Analytical device with lightguide Illumination of capillary and microgrooves arrays  
An analytical cell including a lightguide with a plurality of conduits filled with a migration medium. The medium, the lightguide and a surrounding medium have refractive indices selected such that...
7112266 Multi channel capillary electrophoresis device and method  
Embodiments of a device and method are described which provide for control over the distortion of a sample zone upon exiting an electrophoresis separation channel. According to the teachings herein...
7056427 Electrophoresis apparatus using capillary array and sample plate assembly used therefor  
A sample plate assembly for an electrophoresis apparatus including a tray at a sample supply portion of a capillary array, an adapter for the tray, a sample plate mounted on the adapter, a septer...
7054004 Capillary array and capillary array photodetector  
A multi-focus capillary array that can reduce crosstalk and a capillary array photodetector are provided. On a substrate 20 on which a plurality of capillaries are aligned, a perforation 72 is...
7019831 Separation device substrate including non-fluorescent quencher dye  
A device is provided for the analysis of samples. The device includes a plurality of sample-containment features and a non-fluorescent quenching material for minimizing cross-talk between optical...
7006215 Shaped illumination geometry and intensity using a diffractive optical element  
A method and apparatus to illuminate a target. The apparatus can comprise a first lens configured to receive light from the light source, a diffractive optical element configured to receive the...
7005052 Capillary array  
A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis,...
6977034 Capillary array and electrophoresis apparatus  
A capillary array comprising multiple capillaries and two holding substrates for arranging the aforementioned multiple capillaries in a substantially plane surface by sandwiching at least some of...
6972183 Capillary array-based enzyme screening  
A process for screening an expression library to identify clones expressing enzymes having a desired activity is provided. The process involves first generating from genomic DNA samples of one or...
6936152 Capillary array electrophoresis apparatus and method of separating and analyzing specimen  
At a wall constituting a space for a thermostatic oven in an electrophoresis apparatus, a capillary array attachment portion is formed which permits attachment of a plurality of capillary arrays...
6932940 Optical detection in bio-separation device using axial radiation input  
In a bio-separation system, incident radiation (e.g., from a laser or LED source) for detection of separated analytes is directed at the detection zone axially along the separation medium, instead...
6929779 Optical detection in bio-separation device using axial radiation output  
In a bio-separation system, emitted radiation signals representative of sample analytes are collected from the detection zone axially along the separation medium, instead of through the boundary...
6870165 Multi-color multiplexed analysis in a bio-separation system  
A multi-channel and multi-color bio-separation detection method and apparatus in which a single detector is coupled to a plurality of radiation sources, in a one detector/many radiation sources...
6866824 Capillary array-based sample screening  
Provided are methods of screening and identification of bioactivities and bioactive molecules of interest using a capillary array system. More specifically, disclosed are methods of using optical...
6856390 Time-delay integration in electrophoretic detection systems  
An apparatus for detecting analytes in a sample is provided. The apparatus includes: one or more channels having a detection zone; one or more irradiation sources disposed for irradiating the...
6828567 Optical detection in a multi-channel bio-separation system  
A multi-channel bio-separation detection method and apparatus in which a single detector is coupled to a plurality of radiation sources, in a one detector/many radiation sources configuration. Each...
6808610 Capillary array electrophoresis apparatus  
When irradiating laser beam from the side face of the capillary array, an optical axis of the laser beam is inclined in vertical direction with respect to a plane face formed by the capillary...
6805784 Capillary array  
The structure of a capillary head section is made such that the liquid contacting surfaces of a capillary holder, a capillary, and an adhesive form a plane surface, and this shared liquid...
6794127 Capillary array-based sample screening  
Provided are methods of screening and identification of bio activities and bioactive molecules of interest using a capillary array system. More specifically, disclosed are methods of using optical...
6780300 Device for analyzing samples by multi-capillary electrophoresis with solid/solid temperature regulation  
A device for analyzing samples by electrophoresis comprises a plurality of capillaries, receiver means comprising a multiplicity of independent units each made of a material that is thermally...
6744502 Shaped illumination geometry and intensity using a diffractive optical element  
A method and apparatus to illuminate a target. The apparatus can comprise a first lens configured to receive light from the light source, a diffractive optical element configured to receive the...
6635164 Capillary electrophoresis system  
A capillary electrophoresis system includes a plurality of capillaries arranged in parallel on a vertical plane at an identical distance from each other, each of which has a sample injection end...
6627433 Multi-channel analyte-separation device employing side-entry excitation  
A side-entry excitation arrangement is provided with a multi-channel analyte-separation device. In various embodiments, a plurality of channels are disposed in an array, with a laser disposed to...
6616824 Apparatus for electrophoresis  
An apparatus for electrophoresis includes not only a transparent device for electrophoresis such as a microchip or a capillary having a flow route, a power source for applying a voltage difference...
6596140 Multi-channel capillary electrophoresis device and method  
Embodiments of a device and method are described which provide for control over the distortion of a sample zone upon exiting an electrophoresis separation channel. According to the teachings herein...
6592733 Capillary electrophoresis devices incorporating optical waveguides  
A capillary electrophoresis device having a substrate layer and a cover layer, with a plurality of electrophoresis channels formed in the substrate layer, includes an optical waveguide system that...
6508923 Multi-capillary electrophoretic apparatus  
A data processing part comprises a time-series data production part for producing time-series data as to each capillary column from a scan waveform obtained by an optical measuring part, further...
6497804 Method and apparatus for DNA sequencing  
The development of the network structure and the basic modules of an automated 4-color DNA sequencing apparatus comprising more than one thousand capillary electrophoresis lanes is disclosed. The...
6493459 Image reading apparatus  
An image reading apparatus includes a laser stimulating ray source for emitting a laser beam, a base made of transparent material and bearing thereon an image carrier which carries a fluorescence...
6487351 Fiber optic faceplate  
A fiber optic faceplate for coupling with optical sources or detectors. The optical sources or detectors are arranged in a two-dimensional array. Each of the sources or detectors has a pixel area...
6297061 Simultaneous particle separation and chemical reaction  
This invention provides a method and apparatus for detecting the presence of analyte particles in a sample fluid also comprising larger particles, particularly blood. It exploits diffusion to...
6224733 DNA detector and DNA detection method  
An electrophoresis apparatus includes a plurality of capillaries through which samples labeled with a plurality of fluorophores migrate, a pair of electrodes which generate an electric field which...
6221677 Simultaneous particle separation and chemical reaction  
This invention provides a method and apparatus for detecting the presence of analyte particles in a sample fluid also comprising larger particles, particularly blood. It exploits diffusion to...
6191425 Multicolor fluorescence detection type electrophoretic analyzer  
A plurality of samples are separated into sample components by means of electrophoresis in a plurality of capillaries. Light is radiated onto the separated sample components. Fluorescence emitted...
Matches 1 - 43 out of 43