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7351855 |
Chemically defined non-polymeric valency platform molecules and conjugates thereof
Chemically-defined, non-polymeric valency platform molecules and conjugates comprising chemically-defined valency platform molecules and biological or chemical molecules including polynucleotide...
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7173125 |
Triphosphate oligonucleotide modification reagents and uses thereof
Hydrazino, oxyamino and carbonyl-based monomers and methods for incorporation into oligonucleotides during enzymatic synthesis are provided. Modified oligonucleotides are provided that incorporate...
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7115581 |
Chemically-defined non-polymeric valency platform molecules and conjugates thereof
Chemically-defined, non-polymeric valency platform molecules and conjugates comprising chemically-defined valency platform molecules and biological or chemical molecules including polynucleotide...
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7102024 |
Functional biopolymer modification reagents and uses thereof
Hydrazino, oxyamino and carbonyl-based reagents and methods for incorporation into oligonucleotides during their solid phase synthesis are provided. Modified oligonucleotides are provided that...
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7081242 |
Methods of treating lupus based on antibody affinity and screening methods and compositions for use thereof
The invention provides methods identifying individuals suitable for treatment for lupus and methods of monitoring treatment, based on measuring antibody affinities, as well as of treating lupus...
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6951939 |
Multivalent platform molecules comprising high molecular weight polyethylene oxide
Valency platform molecules comprising high molecular weight polyethylene oxide groups are provided, as well as conjugates thereof with biologically active molecules, and methods for their...
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6585138 |
Device for supplying wrap film
According to this invention, in a device for supplying wrap film, by drawing out a wrap film from a wrap film container and cutting off, a user makes a sheetlike wrap film guide that has the...
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6520395 |
Wrap film supplier
According to this invention, in a device for supplying wrap film, by drawing out a wrap film from a wrap film container and cutting off, a user makes a sheetlike wrap film guide that has the...
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6458953 |
Valency platform molecules comprising carbamate linkages
This invention pertains generally to valency molecules, such as valency platform molecules which act as scaffolds to which one or more molecules may be covalently tethered to form a conjugate. More...
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6399578 |
Conjugates comprising galactose α1,3 galactosyl epitopes and methods of using same
This invention provides conjugates useful for xenotransplantation which comprise a galactose α1,3 galactosyl (αGal) epitope conjugated to a valency platform molecule, preferably a chemically...
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