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7425218 |
Nitric oxide-releasing medical devices
An implant or intravascular stent comprising a polymeric composition capable of releasing nitric oxide under physiological conditions. The polymeric composition comprises a polymer and at least one...
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7226586 |
Highly cross-linked, extremely hydrophobic nitric oxide-releasing polymers and methods for their manufacture and use
Extremely hydrophobic nitric oxide (NO) releasing polymers are disclosed. The extremely hydrophobic NO-releasing polymers provided are extensively cross-linked polyamine-derivatized divinylbenzene...
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6887485 |
Nitric oxide-releasing metallic medical devices
Biocompatible metallic medical devices having silanized surfaces coupled to nucleophile residues that release sustained, therapeutic amounts of nitric oxide to specific sites within a mammalian...
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6706274 |
Differential delivery of nitric oxide
This invention relates to devices and methods for the local, differential delivery of nitric oxide within the body. The devices include devices having at least two differing nitric oxide donor...
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6703046 |
Highly cross-linked, extremely hydrophobic nitric oxide-releasing polymers and methods for their manufacture and use
Extremely hydrophobic nitric oxide (NO) releasing polymers are disclosed. The extremely hydrophobic NO-releasing polymers provided are extensively cross-linked polyamine-derivatized divinylbenzene...
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6645518 |
Uses for medical devices having a lubricious, nitric oxide-releasing coating
Methods are provided for delivering nitric oxide to the vascular tissue of a patient to inhibit or prevent restenosis or improve vascular function following various surgical procedures or...
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6613432 |
Plasma-deposited coatings, devices and methods
Coatings, devices and methods are provided, wherein the contacting surface of a medical device with at least one contacting surface for contacting a bodily fluid or tissue is modified by plasma...
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6410622 |
Method of preventing fouling organisms in marine environments and polymer-bound nitric oxide/nitric oxide-releasing compositions usable therefor
A method of preventing fouling organisms in marine environments comprises the step of introducing into the marine environment in a predetermined form and in a sufficient amount an antifouling...
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6379660 |
Nitric oxide-releasing 1-&lsqb (2-carboxylato)pyrrolidin-1-yl&rsqb diazen-1-ium-1,2-diolates and composition comprising same
A polymeric composition capable of releasing nitric oxide under physiological conditions which includes a biopolymer, such as a peptide, polypeptide, protein, oligonucleotide or nucleic acid, to...
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6299980 |
One step lubricious coating
A coating is provided comprising a polyurethane network formed from the reaction on a substrate to be coated, of a mixture comprising a polyisocyanate; a hydroxyl donor and/or amine donor; a...
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6270779 |
Nitric oxide-releasing metallic medical devices
Biocompatible metallic medical devices having silanized surfaces coupled to nucleophile residues that release sustained, therapeutic amounts of nitric oxide to specific sites within a mammalian...
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6218016 |
Lubricious, drug-accommodating coating
A coating is provided for a substrate comprising a polyisocyanate; an amine donor and/or hydroxyl donor; an isocyanatosilane adduct having terminal isocyanate groups and at least one hydrolyzable...
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6200558 |
Biopolymer-bound nitric oxide-releasing compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same
A polymeric composition capable of releasing nitric oxide under physiological conditions which includes a biopolymer, such as a peptide, polypeptide, protein, oligonucleotide or nucleic acid, to...
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6110453 |
Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same
A polymeric composition capable of releasing nitric oxide including a polymer and a nitric oxide-releasing N 2 O 2 - functional group bound to the polymer; pharmaceutical compositions including...
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6027713 |
Composition and method for the treatment of exercise induced pulmonary hemorrhage
A composition for the treatment of exercise induced pulmonary hemorrhage, particularly in horses. The composition comprises arginine and is formulated for inhalation. The invention includes an...
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