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7381317 |
Methods and compositions for capillary electrophoresis (CE)
This invention relates to improved methods and compositions for conducting Capillary Electrophoresis (CE) to separate molecules on the basis of their respective size or charge.
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7381315 |
Multi-channel analyte-separation device employing side-entry excitation
A side-entry excitation arrangement is provided with a multi-channel analyte-separation device. In various embodiments, a plurality of channels are disposed in an array, with a laser disposed to...
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7361259 |
Capillary array and electrophoresis apparatus, and method
A capillary electrophoresis device including a capillary array, and a method of manufacturing the capillary array, are provided. During the manufacture of the capillary array, a plurality of...
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7329388 |
Electrophoresis apparatus having staggered passage configuration
An electrophoresis apparatus is generally disclosed for sequentially analyzing a single sample or multiple samples having one or more analytes in high or low concentrations. The apparatus comprises...
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7316770 |
Method of electrophoresis, electrophoresis apparatus and capillary array
A method of electrophoresis, an electrophoresis apparatus and a capillary array in which a fluorescently labelled sample is supplied into capillaries in a capillary array constituted by a plurality...
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7280207 |
Time-delay integration in a flow cytometry system
An apparatus for detecting analytes in a sample is provided. The apparatus can include: a flow cytometry system including one or more detection zones; one or more irradiation sources disposed for...
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7265833 |
Electrophoretic system with multi-notch filter and laser excitation source
Apparatus and methods for detecting analytes in a sample are provided. The apparatus can include: one or more channels having a detection zone; one or more irradiation sources disposed for...
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7262847 |
Optical assembly and method for detection of light transmission
An optical assembly comprising a light source, at least one sample vessel and a detector. The detector comprises a plurality of detector locations and the vessel comprises a wall and core of...
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7253557 |
Light source provided with a housing enclosing voltage regulator means and method of manufacturing thereof
A light source for testing sites using a fluorescent dye is described. The light source can include a low voltage lamp or a low heat generating lamp.
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7250098 |
Multi-capillary array electrophoresis device
An electrophoresis apparatus includes a multi-capillary array having a liquid or solid disposed between the capillaries of the array. The liquid or solid exhibits a refractive index higher than...
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7189361 |
Analytical device with lightguide Illumination of capillary and microgrooves arrays
An analytical cell including a lightguide with a plurality of conduits filled with a migration medium. The medium, the lightguide and a surrounding medium have refractive indices selected such that...
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7157724 |
Detection lamp
A light source for testing sites using a fluorescent dye is described. The light source can include a low voltage lamp or a low heat generating lamp. An emission from the fluorescent dye can be...
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7153407 |
Multi-dimensional electrophoresis apparatus
An electrophoresis apparatus is generally disclosed for sequentially analyzing a single sample or multiple samples having one or more analytes in high or low concentrations. The apparatus comprises...
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7118659 |
Robotic friendly external loading system for electrophoresis instrument and method
An electrophoresis instrument for analyzing multiple samples having a loading system. The loading system having a carriage moveable between an external station and a sampling station. The carriage...
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7085428 |
Image data forming method and apparatus
An image forming method and apparatus that improves the S/N ratio of a low frequency component without causing losses to the data of a high frequency component. Low frequency image data...
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7056427 |
Electrophoresis apparatus using capillary array and sample plate assembly used therefor
A sample plate assembly for an electrophoresis apparatus including a tray at a sample supply portion of a capillary array, an adapter for the tray, a sample plate mounted on the adapter, a septer...
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7054004 |
Capillary array and capillary array photodetector
A multi-focus capillary array that can reduce crosstalk and a capillary array photodetector are provided. On a substrate 20 on which a plurality of capillaries are aligned, a perforation 72 is...
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7019831 |
Separation device substrate including non-fluorescent quencher dye
A device is provided for the analysis of samples. The device includes a plurality of sample-containment features and a non-fluorescent quenching material for minimizing cross-talk between optical...
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7005052 |
Capillary array
A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis,...
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6977034 |
Capillary array and electrophoresis apparatus
A capillary array comprising multiple capillaries and two holding substrates for arranging the aforementioned multiple capillaries in a substantially plane surface by sandwiching at least some of...
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6953521 |
Automated parallel capillary electrophoresis system with hydrodynamic sample injection
An automated capillary zone electrophoretic system is disclosed. The system employs a capillary cartridge having a plurality of capillary tubes. The cartridge has a first array of capillary ends...
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6936152 |
Capillary array electrophoresis apparatus and method of separating and analyzing specimen
At a wall constituting a space for a thermostatic oven in an electrophoresis apparatus, a capillary array attachment portion is formed which permits attachment of a plurality of capillary arrays...
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6888628 |
Energy beam guide for an electrophoresis system
The energy beam guide comprises a first region having a first refractive index, the first region having an energy beam receiving end and an inclined first boundary opposing the energy beam...
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6878254 |
Size separation of analytes using monomeric surfactants
A sieving medium for use in the separation of analytes in a sample containing at least one such analyte comprises a monomeric non-ionic surfactant of the of the general formula, B-A, wherein A is a...
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6856390 |
Time-delay integration in electrophoretic detection systems
An apparatus for detecting analytes in a sample is provided. The apparatus includes: one or more channels having a detection zone; one or more irradiation sources disposed for irradiating the...
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6833919 |
Multiplexed, absorbance-based capillary electrophoresis system and method
A multiplexed, absorbance-based electrophoresis system for analyzing multiple samples simultaneously without use of a mask or slit comprising a light source, a planar array of capillary tubes and a...
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6808610 |
Capillary array electrophoresis apparatus
When irradiating laser beam from the side face of the capillary array, an optical axis of the laser beam is inclined in vertical direction with respect to a plane face formed by the capillary...
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6805784 |
Capillary array
The structure of a capillary head section is made such that the liquid contacting surfaces of a capillary holder, a capillary, and an adhesive form a plane surface, and this shared liquid...
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6799629 |
Cooling apparatus for a multiplexed capillary electrophoresis system
Apparatus for cooling a bundle of capillary tubes to prevent overheating of the tubes during a parallel capillary electrophoresis procedure. The apparatus includes a jacket of thermally conductive...
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6731437 |
Energy beam guide for an electrophoresis system
The energy beam guide comprises a first region having a first refractive index, the first region having an energy beam receiving end and an inclined first boundary opposing the energy beam...
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6627433 |
Multi-channel analyte-separation device employing side-entry excitation
A side-entry excitation arrangement is provided with a multi-channel analyte-separation device. In various embodiments, a plurality of channels are disposed in an array, with a laser disposed to...
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6592733 |
Capillary electrophoresis devices incorporating optical waveguides
A capillary electrophoresis device having a substrate layer and a cover layer, with a plurality of electrophoresis channels formed in the substrate layer, includes an optical waveguide system that...
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6576108 |
DNA detector and DNA detection method
An electrophoresis apparatus includes an optical cell having an outlet for fluid and filled with a buffer solution, and a plurality of electrophoresis lanes, each including a separation medium,...
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6572750 |
Hydrodynamic injector
A hydrodynamic injector for substantially concurrently loading fluid samples to be analyzed into multiple capillary tubes of a capillary electrophoresis system. The injector includes an enclosure...
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6544396 |
Multiplexed capillary electrophoresis system
A multiplexed capillary electrophoresis system with cooling sufficient to prevent overheating during chiral separation. The system includes a thermally insulated enclosure enclosing a bundle of...
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6542691 |
Glass capillary array for fluorescence analysis and manufacturing method thereof
A glass capillary array for fluorescence analysis is provided which is capable of preventing reduction of the transmittance of a laser beam through the glass capillaries during electrophoretic DNA...
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6531041 |
Multiplexed capillary electrophoresis system with rotatable photodetector
A parallel capillary electrophoresis system for separating and analyzing the components of multiple chemical samples. The system comprises a bundle of capillary tubes arrayed to have at least...
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6518556 |
Large dynamic range light detection
System for large dynamic range light detection. In one aspect, the system includes a hybrid counting/integrating system for processing a signal from a photomultiplier tube. In another aspect, large...
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6508923 |
Multi-capillary electrophoretic apparatus
A data processing part comprises a time-series data production part for producing time-series data as to each capillary column from a scan waveform obtained by an optical measuring part, further...
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6464852 |
Multicapillary bundle for electrophoresis and detection for DNA
A multichannel electrophoretic cassette structure is disclosed comprising distinct regions for loading and detection with different spacing between channels. A method and an apparatus are further...
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6462816 |
Parallel capillary electrophoresis system having signal averaging and noise cancellation
A multiplexed capillary electrophoresis system and process including a bundle of capillary tubes, a power source, a light source, a processor and an array of photodetector elements. Each element of...
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6445448 |
System and method for molecular sample measurement
A system for aligning the optical components of a chemical analysis system in which capillaries or optical fibers are supported by a substrate. The system provides for alignment of elements of an...
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EP1212608A1 |
AUTOMATED PARALLEL CAPILLARY ELECTROPHORESIS SYSTEM WITH HYDRODYNAMIC SAMPLE INJECTION
Abstract not available for EP1212608 Abstract of corresponding document: WO0116587 An automated capillary zone electrophoretic system is disclosed. The system employs a capillary cartridge (102)...
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6404495 |
System and method for molecular sample measurement
A system for aligning the optical components of a chemical analysis system in which capillaries or optical fibers are supported by a substrate. The system provides for alignment of elements of an...
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6387234 |
Integrated multiplexed capillary electrophoresis system
The present invention provides an integrated multiplexed capillary electrophoresis system for the analysis of sample analytes. The system integrates and automates multiple components, such as...
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6355921 |
Large dynamic range light detection
System for large dynamic range light detection. In one aspect, the system includes a hybrid counting/integrating system for processing a signal from a photomultiplier tube. In another aspect, large...
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6236944 |
Expert system for analysis of DNA sequencing electropherograms
A method of analyzing DNA fragments separated electrophoretically is presented. The method includes the use of an expert system that interprets raw or preprocessed signal from the separation. The...
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6224733 |
DNA detector and DNA detection method
An electrophoresis apparatus includes a plurality of capillaries through which samples labeled with a plurality of fluorophores migrate, a pair of electrodes which generate an electric field which...
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6191425 |
Multicolor fluorescence detection type electrophoretic analyzer
A plurality of samples are separated into sample components by means of electrophoresis in a plurality of capillaries. Light is radiated onto the separated sample components. Fluorescence emitted...
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6156177 |
DNA detector and DNA detection method
A method for analyzing samples includes the steps of introducing samples labeled with fluorophores into a first end of each of a plurality of electrophoresis lanes including a separation medium, a...
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