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7403805 |
Apparatus and method for noninvasive measurement of analytes from the conjunctiva using mid-infrared radiation
Utilization of a contact device placed on the eye in order to detect physical and chemical parameters of the body as well as the non-invasive delivery of compounds according to these physical and...
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7398119 |
Assessing blood brain barrier dynamics or identifying or measuring selected substances, including ethanol or toxins, in a subject by analyzing Raman spectrum signals
A non-invasive method for analyzing the blood-brain barrier includes obtaining a Raman spectrum of a selected portion of the eye and monitoring the Raman spectrum to ascertain a change to the...
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7395104 |
Methods and devices for non-invasively measuring quantitative information of substances in living organisms
Disclosed are systems and methods of determining the amount of a substance in a living organism. In one embodiment, the method comprises: applying an electrical signature signal to the living...
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7377643 |
Method and apparatus for eye imaging with position registration and constant pupil size
A method for capturing an image of an eye having an iris, including the steps of determining a plurality of measurement origins in the image; detecting an edge of the iris; determining a distance...
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RE40316 |
Method and device for glucose concentration measurement with special attention to blood glucose determinations
The concentration of glucose in the anterior chamber of an eye is non-invasively measured by guiding a beam through a polarizer ( 4 ), a quarter wave plate ( 6 ), a polarization modulator ( 20 ),...
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7356365 |
Method and apparatus for tissue oximetry
In accordance with the invention, the oxygenation of blood-profused tissue is measured by shining light into the profused tissue and analyzing the light reflected within the tissue. The light is...
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7339170 |
Optical encoding and reconstruction
The invention features methods including: (i) modulating multiple components (e.g., different spatial regions, different wavelengths, or both) of electromagnetic (EM) radiation emerging from an...
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7321791 |
Spectral imaging of deep tissue
Apparatus and methods are provided for the imaging of structures in deep tissue within biological specimens, using spectral imaging to provide highly sensitive detection. By acquiring data that...
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7308293 |
Non-invasive glucose meter
An apparatus for measuring a concentration of a substance in an eye ( 13 ) includes a measurement light source ( 4 ) producing a measurement light beam having a first wavelength at which the...
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7307734 |
Interferometric sensor for characterizing materials
An integrated optical sensor, using low coherence interferometry, is capable of determining analyte concentration in a material sample based on absorption, scattering and polarization. The sensor...
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7254429 |
Method and apparatus for monitoring glucose levels in a biological tissue
In accordance with the invention, a low coherence interferometer is used to non-invasively monitor the concentration of glucose in blood by shining a light over a surface area of human or animal...
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7233817 |
Apparatus and method for pattern delivery of radiation and biological characteristic analysis
The present invention uses a high signal to noise ratio method and apparatus to analyze a characteristic of a biological object, such as blood glucose level. The method and apparatus can also have...
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7187960 |
Apparatus and method for measuring biologic parameters
Support structures for positioning sensors on a physiologic tunnel for measuring physical, chemical and biological parameters of the body and to produce an action according to the measured value of...
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7181261 |
Implantable, retrievable, thrombus minimizing sensors
A sensor is disclosed, for implantation within a blood vessel to monitor a substance in or property of blood. In one embodiment, the sensor is retrievable. In another embodiment, the sensor has a...
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7167736 |
Non-invasive measurement system and method for measuring the concentration of an optically-active substance
A method and system for non-invasively measuring the concentration of an optically-active substance in a subject are provided. The system includes a light source adapted to transmit light towards a...
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7050847 |
Non-invasive in vivo determination of body fluid parameter
A non-invasive method of monitoring a biological parameter concerning a bodily fluid of a subject, e.g., blood glucose of a human subject. The method includes: placing an electrode against a site...
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7041063 |
Noninvasive measurement of chemical substances
Utilization of a contact device placed on the eye in order to detect physical and chemical parameters of the body as well as the non-invasive delivery of compounds according to these physical and...
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7039447 |
Glucose measurement utilizing non-invasive assessment methods
This involves non-invasive glucose measurement processes for determining blood glucose level in the human body. After achieving a static level of glucose at a surface of the skin over some period...
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7033322 |
Implantable sensor
A sensor is disclosed, for implantation within a blood vessel to monitor an analyte in blood. In one embodiment, the analyte is glucose. A signal indicative of glucose level is transmitted to an...
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7006858 |
Implantable, retrievable sensors and immunosensors
A sensor is disclosed, for implantation within a blood vessel to monitor an analyte in blood. In one embodiment, the sensor is retrievable. In another embodiment, the sensor is an immunosensor. A...
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6999808 |
Method and device for glucose concentration measurement with special attention to blood glucose determinations
The concentration of glucose in the anterior chamber of an eye is non-invasively measured by guiding a beam through a polarizer ( 4 ), a quarter wave plate ( 6 ), a polarization modulator ( 20 ),...
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6975892 |
Methods for non-invasive analyte measurement from the conjunctiva
The present invention is related to non-invasive methods and instruments to detect the level of analyte concentrations in the tissue of a subject by measuring electromagnetic radiation signatures...
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EP1600104A1 |
Determination of biological conditions using impedance measurements
Apparatus and method for the diagnostics of biological conditions using impedance measurements, and in particular for the diagnostics of a diseased condition of the skin of a subject, for example,...
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6968222 |
Methods and device for non-invasive analyte measurement
The present invention is related to optical non-invasive methods and instruments to detect the level of analyte concentrations in the tissue of a subject. The spectra of mid-infrared radiation...
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6961599 |
Identifying or measuring selected substances or toxins in a subject using resonant raman signals
Methods and systems of the present invention identify the presence of and/or the concentration of a selected analyte in a subject by: (a) illuminating a selected region of the eye of a subject with...
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6958039 |
Method and instruments for non-invasive analyte measurement
The present invention is related to optical non-invasive methods and instruments to detect the level of analyte concentrations in the tissue of a subject. The spectra of mid-infrared radiation...
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6934030 |
Method and apparatus for detecting radiation
In analyzing radiation from a sample, single-quanta counting can be used to advantage especially at low levels of radiation energy, e.g. in the detection of fluorescent radiation. Preferred...
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6930773 |
Spectral imaging
A method is described that includes measuring, at each of a set of W wavelength bins, a spectral response of at least one region of a sample stained with multiple stains, and determining the...
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6895265 |
Implantable sensor
A sensor is disclosed, for implantation within a blood vessel to monitor an analyte in blood. In one embodiment, the analyte is glucose. A signal indicative of glucose level is transmitted to an...
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6895264 |
Non-invasive psychophysical measurement of glucose using photodynamics
Blood glucose concentrations are measured by non-invasive methods and apparatus using visual pigment bleaching in conjunction with psychophysical methodologies. Bleaching light of selected...
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6889069 |
Non-invasive measurement of blood analytes using photodynamics
The determination of blood glucose in an individual is carried out by projecting illuminating light into an eye of the individual to illuminate the retina with the light having wavelengths that are...
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6882777 |
Optical waveguide diffraction grating device, method for fabricating optical waveguide diffraction grating device, multiplexing/demultiplexing module, and optical transmission system
The present invention relates to a diffraction grating device in which a diffraction grating based on perturbation of refractive index is formed through a predetermined range in a light guide...
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6850786 |
Ocular analyte sensor
An ophthalmic lens comprising a receptor moiety can be used to determine the amount of an analyte in an ocular fluid. The receptor moiety can bind either a specific analyte or a detectably labeled...
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6836325 |
Optical probes and methods for spectral analysis
The present invention relates to spectral analysis systems and methods for determining physical and chemical properties of a sample by measuring the optical characteristics of light emitted from...
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6802812 |
Noninvasive optical sensor for measuring near infrared light absorbing analytes
An optical sensor includes an optical source capable of being positioned on a tissue and emitting near infrared light into the tissue at a plurality of selected wavelengths, and a photodetector...
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6775564 |
Non-invasive glucose measuring device and method for measuring blood glucose
A glucose measuring device for determining the concentration of glucose in intravascular blood within a body part of a subject. The device includes at least one light source having a wavelength of...
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EP1437091A1 |
Determination of biological conditions using impedance measurements
Abstract not available for EP1437091
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6760109 |
Method and apparatus for detecting radiation
In analyzing radiation from a sample, single-quanta counting can be used to advantage especially at low levels of radiation energy, e.g. in the detection of fluorescent radiation. Preferred...
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6753966 |
Optical probes and methods for spectral analysis
The present invention relates to spectral analysis systems and methods for determining physical and chemical properties of a sample by measuring the optical characteristics of light emitted from...
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6750964 |
Spectral imaging methods and systems
A imaging method is described that includes: obtaining a spectral weighting function indicative of an attribute of the reference sample; illuminating a target sample with light whose spectral flux...
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6704588 |
Method and apparatus for the non-invasive measurement of blood glucose levels in humans
An apparatus ( 10 ) for determining a diagnostic glucose level in a human subject includes a light source ( 30 ) that produces collimated light at a selected wavelength. The collimated light is...
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6694157 |
Method and apparatus for determination of pH pCO2, hemoglobin, and hemoglobin oxygen saturation
This invention relates to a method and apparatus for in-vivo, real time measurement of pH, pCO 2 , base excess, hemoglobin, and hemoglobin oxygen saturation. Specifically, the invention relates to...
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6690466 |
Spectral imaging system
An imaging system is disclosed comprising an illuminator which produces illumination of any desired pure wavelength or of any selected mixture of pure wavelengths simultaneously, which illuminates...
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6687389 |
Imaging apparatus
An imaging apparatus suitable for capturing a image of one or more of a user's facial features is disclosed. The apparatus includes a spherical cold mirror which presents a concave surface to the...
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6681127 |
Ocular analyte sensor
An ophthalmic lens comprising a receptor moiety can be used to determine the amount of an analyte in an ocular fluid. The receptor moiety can bind either a specific analyte or a detectably labeled...
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6675030 |
Near infrared blood glucose monitoring system
An individualized modeling equation for predicting a patient's blood glucose values is generated as a function of non-invasive spectral scans of a body part and an analysis of blood samples from...
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6611704 |
Apparatus for measuring the autofluorescence of the cornea of an eye
For the early detection of blindness-causing diabetic retinopathy, an apparatus for measuring the autofluorescence of the cornea of an eye, comprising means for tangentially illuminating the...
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6574501 |
Assessing blood brain barrier dynamics or identifying or measuring selected substances or toxins in a subject by analyzing Raman spectrum signals of selected regions in the eye
A non-invasive method for analyzing the blood-brain barrier includes obtaining a Raman spectrum of a selected portion of the eye and monitoring the Raman spectrum to ascertain a change to the...
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6549861 |
Automated system and method for spectroscopic analysis
An automated method for modeling spectral data is provided, wherein the spectral data generated by one of diffuse reflectance, clear transmission, or diffuse transmission. The method includes...
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6522903 |
Glucose measurement utilizing non-invasive assessment methods
This involves non-invasive glucose measurement processes for determining blood glucose level in the human body. After achieving a static level of glucose at a surface of the skin over some period...
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