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7387891 |
Optical instrument including excitation source
An optical instrument is provided for simultaneously illuminating two or more spaced-apart reaction regions with an excitation beam generated by a light source. A collimating lens can be disposed...
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7341557 |
Compact fluorescence endoscopy video system
A fluorescence endoscopy video system includes a multimode light source that produces light for color and fluorescence imaging modes. Light from the light source is transmitted through an endoscope...
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7330268 |
Spectral imaging apparatus and methodology
A method and apparatus for an improved spectral imaging system is provided. The system is capable of measuring the fluorescence, luminescence, or absorption at selected locations on a sample plate....
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7312919 |
Wide field of view and high speed scanning microscopy
A wide field of view scanning microscope includes a light source, a light detector, optics, a scanning assembly, a translation system, and a data collection control and processing unit. The...
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EP1099106B1 |
IMPROVED IMAGING SYSTEM FOR LUMINESCENCE ASSAYS
Abstract not available for EP1099106 Abstract of corresponding document: US6791687 Apparatus for detecting light emitted by an assay sample is provided, in which light emitted by the sample is...
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7158224 |
Optically active substrates
A device for optical examination of biological materials using radiation of a selected wavelength includes a substrate having a first surface and a second surface opposite to the first surface. The...
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7081954 |
Microarray detector and synthesizer
The present invention relates to novel systems, devices, and methods comprising spatial light modulators for use in the reading and synthesis of microarrays. For example, the present invention...
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6984828 |
Quantified fluorescence microscopy
The present invention relates to calibration apparatuses, methods or tools used in microscopy. A calibration tool for fluorescent microscopy includes a support, a solid surface layer including a...
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6970492 |
DUV and VUV laser with on-line pulse energy monitor
A beam parameter monitoring unit for coupling with an excimer or molecular fluorine (F 2 ) laser resonator that produces an output beam having a wavelength below 200 nm includes an on-line laser...
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6965105 |
Scanning system and method for scanning a plurality of samples
A system for detecting fluorescence emitted from a plurality of samples in a sample tray is provided. The system generally includes a plurality of lenses positioned in a linear arrangement, a...
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6921908 |
Methods for fluorescence detection that minimizes undesirable background fluorescence
The present invention provides a method for the excitation of a fluorescent sample and the measurement of the fluorescent emission. The method of the present invention has the advantage of...
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6899675 |
Fluorescence endoscopy video systems with no moving parts in the camera
A fluorescence endoscopy video system includes a multi-mode light source that produces light for white light and fluorescence imaging modes. Light from the light source is transmitted through an...
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6839375 |
On-line quality control of the key optical components in lithography lasers using laser induced fluorescence
Some of the key optical components of lithography lasers are very sensitive to intensive UV radiation. Intensive UV radiation can cause color center formation in these components. The color centers...
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6821245 |
Compact fluorescence endoscopy video system
A fluorescence endoscopy video system includes a multimode light source that produces light for color and fluorescence imaging modes. Light from the light source is transmitted through an endoscope...
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6806954 |
Microarray detector and synthesizer
The present invention relates to novel systems, devices, and methods comprising spatial light modulators for use in the reading and synthesis of microarrays. For example, the present invention...
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6791687 |
Imaging system for luminescence assays
Apparatus for detecting light emitted by an assay sample is provided, in which light emitted by the sample is collected for transmission to a photosensitive detector such as a charge coupled device...
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6741344 |
Method and apparatus for detection of fluorescently labeled materials
Fluorescently marked targets bind to a substrate 230 synthesized with polymer sequences at known locations. The targets are detected by exposing selected regions of the substrate 230 to light...
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6603552 |
Portable system for detecting skin abnormalities based on characteristic autofluorescence
A lightweight hand-held skin abnormality detection system includes a source of excitation light that causes tissue under examination to produce fluorescence light. The fluorescence light produced...
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6597000 |
Systems and methods for detection of labeled materials
Labeled targets on a support synthesized with polymer sequences at known locations according to the methods disclosed in U.S. Pat. No. 5,143,854 and PCT WO 92/10092 or others, can be detected by...
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6567163 |
Microarray detector and synthesizer
The present invention relates to novel systems, devices, and methods comprising spatial light modulators for use in the reading and synthesis of microarrays. For example, the present invention...
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6545758 |
Microarray detector and synthesizer
The present invention relates to novel systems, devices, and methods comprising spatial light modulators for use in the reading and synthesis of microarrays. For example, the present invention...
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6472671 |
Quantified fluorescence microscopy
A calibration tool for fluorescent microscopy comprises a support on which is carried a solid surface layer comprised of effective fluorophores, and a thin mask of non-fluorescent material defining...
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6462770 |
Imaging system with automatic gain control for reflectance and fluorescence endoscopy
An imaging system for white light and fluorescence endoscopy that includes an automatic gain control circuit 30 that adjusts the brightness of an image produced based on distribution of pixel...
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6455861 |
Fluorescence polarization assay system and method
An instrument is disclosed for fluorescence assays which is capable of reading many independent samples at the same time. This instrument provides enhanced throughput relative to single-sample...
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6403311 |
Methods of analyzing polymers using ordered label strategies
The invention relates to methods and products for analyzing polymers. The polymers are analyzed by reconstructing sequence information from population data sets. The data sets include information...
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6355938 |
Phosphor screen scanning systems
A system for scanning an imaging plate, comprising: a continuous belt drive; a first scanning head mounted to the belt drive; a second scanning head mounted to the belt drive; and a laser...
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6355420 |
Methods and products for analyzing polymers
Methods and products for analyzing polymers are provided. The methods include methods for determining various other structural properties of the polymers.
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6335824 |
Wide field of view and high speed scanning microscopy
Limited rotation, micro-lens scanning of DNA arrays, microscope slides, biological materials, etc., is performed by arcuate and translational motion. A scanning system includes an objective lens...
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6300638 |
Modular probe for total internal reflection fluorescence spectroscopy
An instrument for total internal reflection fluorescence spectroscopy having modular probe that inexpensively monitors vapors and liquid-phase analytes under field conditions is described. The...
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EP0987539B1 |
Measuring device with at least one excitation source
Abstract of EP0987539 The measurement arrangement has a first luminescence detector and at least one further luminescence optical sensor element (2) arranged on the first barrier surface (11) of a...
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6252235 |
Apparatus for imaging fluorescent particles
An apparatus for imaging fluorescent particles comprises an imaging vessel having a lower section defining an interior space for containing fluorescent particles, the lower section having a side...
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6210896 |
Molecular motors
The present invention relates to molecular motors and their use in linear analysis of polymers. In particular, molecular motors are used to move polymers with respect to a station such that...
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6207960 |
System and methods for detection of labeled materials
Labeled targets on a support synthesized with polymer sequences at known locations according to the methods disclosed in U.S. Pat. No. 5,143,854 and PCT WO 92/10092 or others, can be detected by...
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6201639 |
Wide field of view and high speed scanning microscopy
Wide angle, limited rotation, on-axis scanning with a micro objective lens, which is preferably aspheric, and is mounted on a rigid rotary structure that oscillates about a limited arc while a...
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6185030 |
Wide field of view and high speed scanning microscopy
Wide angle, limited rotation, on-axis scanning with a micro lens that preferably is aspheric. Predetermined defocusing of some wavelengths relative to others in opposite sense to chromatic...
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6108082 |
Spectral imaging apparatus and methodology
A method and apparatus for an improved spectral imaging system is provided. The system is capable of measuring the fluorescence, luminescence, or absorption at selected locations on a sample plate....
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6043506 |
Multi parameter scanner
An apparatus capable of measuring quantities of biological or other types of samples that have been labeled using any of a variety of techniques including fluorescence, radioisotopes, enzyme...
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EP0987539A1 |
Measuring device with at least one excitation source
The measurement arrangement has a first luminescence detector and at least one further luminescence optical sensor element (2) arranged on the first barrier surface (11) of a carrier element,...
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5981956 |
Systems and methods for detection of labeled materials
Labeled targets on a support synthesized with polymer sequences at known locations according to the methods disclosed in U.S. Pat. No. 5,143,854 and PCT WO 92/10092 or others, can be detected by...
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5895915 |
Bi-directional scanning system with a pixel clock system
A bi-directional optical scanning system includes a spring-stiffened, taut-band mechanical subsystem that translates rotational motion of a servo-controlled actuator to translational (scan line or...
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5861256 |
Methods and apparatus for detection and discrimination of multiple analytes using flourescent technology
The present invention provides methods and apparatus for detecting and discriminating multiple analytes within a test sample which are rapid, accurate, and convenient enough for routine use in a...
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5793049 |
Optical filtering and spectroscopic imaging
An imaging scheme for illuminating an object having a plurality of fluors comprising: a light source for simultaneously illuminating the object with light having a plurality of separate excitation...
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5723294 |
Methods for detection and discrimination of multiple analytes using fluorescent technology
The present invention provides methods and apparatus for detecting and discriminating multiple analytes within a test sample which are rapid, accurate, and convenient enough for routine use in a...
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EP0794261A2 |
Methods for detection and discrimination of multiple analytes using fluorescent technology
The present invention provides methods and apparatus for detecting and discriminating multiple analytes within a test sample which are rapid, accurate, and convenient enough for routine use in a...
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5511103 |
Method of X-ray mapping analysis
The sample stage is scanned in a grid pattern with a feed pitch finer than the width of the primary beams, and with X-ray intensities at each point as values, primary and secondary mapping data are...
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