Matches 1 - 41 out of 41
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7413753 Calcium phosphate delivery vehicles for osteoinductive proteins  
A composition for delivery of osteogenic proteins is disclosed. The composition comprises an osteogenic protein, a calcium phosphate material as a carrier, and an effective amount of an...
7410947 Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects  
Disclosed herein are improved osteogenic devices and methods of use thereof for repair of bone and cartilage defects. The devices and methods promote accelerated formation of repair tissue with...
7390498 Method of forming bone with porous βtricalcium phosphate granules  
A porous β-tricalcium phosphate material for bone implantation is provided. The multiple pores in the porous TCP body are separate discrete voids and are not interconnected. The pore size diameter...
7383946 Materials for storing and releasing reactive gases  
Compositions, methods, and devices are provided for use in containing and releasing a gas, particularly a reactive gas. The composition can include a reactive gas, reactive gas precursor, or...
7365052 Tendon-inducing methods  
Compositions of proteins with tendon/ligament-like tissue inducing activity are disclosed. The compositions are useful in the treatment of tendinitis and tendon or ligament defects and in related...
7357941 Method of delivering a bioactive agent with porous β-tricalcium phosphate granules  
A porous β-tricalcium phosphate material for bone implantation is provided. The multiple pores in the porous TCP body are separate discrete voids and are not interconnected. The pore size diameter...
7348021 Immunostimulating coating for surgical devices  
The present invention discloses an immunostimulating agent that may be applied to various surgical devices to promote rapid healing and the ready acceptance and integration of the surgical devices...
7323445 Methods and compositions for healing and repair of articular cartilage  
Methods and compositions are provided for the treatment of articular cartilage defects and disease involving the combination of tissue, such as osteochondral grafts, with active growth factor. The...
7322825 Method of treating periodontal disease using periodontal regeneration composition  
A periodontal structure regeneration composition for treatment of periodontal disease is a mixture of particles of a bone growth material and free collagen. The periodontal regeneration composition...
7300772 BMP products  
Purified BMP-2 and BMP-4 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue...
7226587 Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins  
Compositions and methods for systemic administration of DNA encoding bone morphogenic proteins for promotion of osteogenesis are disclosed. The compositions and methods of the invention may be...
7217691 Methods of treatment of periodontal disease  
Purified BMP-2 and BMP-4 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue...
7211271 Method to improve hydroxyapatite implantation and stimulate bone regeneration  
Hydroxyapatite is treated by a combination of nitridation and the application of bone morphogenetic protein or DNA encoding such a protein to improve the tissue compatibility and affinity of the...
7201841 Composite materials for fluid treatment  
This invention relates generally to composite materials and to devices which may alter fluid parameters. Devices incorporating the composite materials of the invention are used to deliver, remove,...
7189392 Injectable carrier formulations of hyaluronic acid derivatives for delivery of osteogenic proteins  
An injectable formulation is disclosed for delivery of osteogenic proteins. The formulation comprises a pharmaceutically acceptable admixture of an osteogenic protein; and formulations comprising...
7105182 Periodontal regeneration composition and method of using same  
A periodontal structure regeneration composition for treatment of periodontal disease is a mixture of particles of a bone growth material and free collagen. All particles are sized to be less than...
7101545 Method for using human intervertebral disc cells  
There is provided a method for growing human intervertebral cells. Disc tissue is surgically removed from a normal disc of a patient, the cells expanded by feeding with a cell stimulant such as a...
7091007 DNA molecules encoding BMP receptor proteins  
Novel serine/threonine receptor proteins and BMP receptor proteins are disclosed, as well as DNA molecules encoding the BMP receptor proteins and methods of using the receptor proteins. Further...
7045141 Allograft bone composition having a gelatin binder  
The invention is directed toward an osteoimplant for application to a bone defect site to promote new bone growth at the site which comprises a new bone growth inducing composition of demineralized...
7041641 Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects  
Disclosed herein are improved osteogenic devices and methods of use thereof for repair of bone and cartilage defects. The devices and methods promote accelerated formation of repair tissue with...
7034114 “Signalin” family of TGFβ signal transduction proteins, and uses related thereto  
The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here signalin-related genes, which are involved in signal transduction induced by members...
7022683 Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation  
The inventions disclosed herein relate to compositions for the sustained release of pharmacological agents comprising pectins having a combination of both a high molecular weight and a low degree...
6984623 Tendon-inducing compositions  
Compositions of proteins with tendon/ligament-like tissue inducing activity are disclosed. The compositions are useful in the treatment of tendinitis and tendon or ligament defects and in related...
EP1604649A1 Composite material for use as protein carrier  
Abstract not available
6957743 Microbiological water filter  
A method and device for the filtration and/or purification of fluids water or other solutions containing microbiological contaminants, such as fluids containing including bacteria and/or viruses,...
6949251 Porous β-tricalcium phosphate granules for regeneration of bone tissue  
A porous β-tricalcium phosphate material for bone implantation is provided. The multiple pores in the porous TCP body are separate discrete voids and are not interconnected. The pore size diameter...
6703377 Method of promoting bone growth with hyaluronic acid and growth factors  
A bone growth-promoting composition is provided comprising hyaluronic acid and a growth factor. The composition has a viscosity and biodegradability sufficient to persist at an intra-articular site...
6645945 Method of treating diseased, injured or abnormal cartilage with hyaluronic acid and growth factors  
A composition is provided for treating diseased, injured or diseased cartilage comprising hyaluronic acid and a growth factor. The composition has a viscosity and biodegradability sufficient to...
6596293 Polyurethane-biopolymer composite  
A method is provided for preparing a drug delivery material and device comprising cross-linking a biological polymer with a cross-linking agent and loading the cross-linked biopolymer with a...
6428977 Signalin family of TGFβ signal transduction proteins, and uses related thereto  
The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here signalin-related genes, which are involved in signal transduction induced by members...
6358532 Calcium phosphate microcarriers and microspheres  
The present invention provides calcium phosphate-based (CaP) microcarriers and their use, for example, in cell culturing systems, chromatography, and implantable biomedical materials.
6313103 Pectic substance as a growth factor stabilizer  
Pectic substance from Aloe Vera and other sources is used as a stabilizer and a delivery vehicle for pectin/heparin-binding proteins, such as pectin/heparin binding growth factors. Aloe pectin, a...
6303112 Enriched platelet wound healant  
A wound healant composition comprising a therapeutically effective amount of activated growth factors and ascorbic acid and/or at least one retinoid and/or at least one antibiotic, that facilitates...
6274548 Pectic substance as a growth factor stabilizer  
Pectic substance from Aloe Vera and other sources is used as a stabilizer and a delivery vehicle for pectin/heparin-binding proteins, such as pectin/heparin binding growth factors. Aloe pectin, a...
6221854 Method of promoting bone growth with hyaluronic acid and growth factors  
A bone growth-promoting composition is provided comprising hyaluronic acid and a growth factor. The composition has a viscosity and biodegradability sufficient to persist at an intra-articular site...
6187192 Microbiological water filter  
A method and device for the filtration and/or purification of fluids water or other solutions containing microbiological contaminants, such as fluids containing including bacteria and/or viruses,...
6080579 Method for producing human intervertebral disc cells  
There is provided a method for growing human intervertebral cells. Disc tissue is surgically removed from a normal disc of a patient, the cells expanded by feeding with a cell stimulant such as a...
5942499 Method of promoting bone growth with hyaluronic acid and growth factors  
A bone growth-promoting composition is provided comprising hyaluronic acid and a growth factor. The composition has a viscosity and biodegradability sufficient to persist at the site of desired...
5929051 Aloe pectins  
Pectins from gel and rind cell wall fibers of Aloe vera are extracted, isolated and identified. Two classes of Aloe pectin are obtained: the high-molecular-weight (HMW) pectin and the...
5888967 Use of plasminogen activators to stimulate local bone growth  
Described herein is a method of promoting osteogenesis in a patient in need thereof by administering a plasminogen activator which activates the zymogen plasminogen by cleavage between arginine 506...
5702695 Osseointegration promoting implant composition, implant assembly and method therefor  
A liquid composition comprising a transforming growth factor β(TGF-/β in a polyoxyalkylene block copolymer--containing liquid carrier which gels at about 37 C, promotes osseointegration of an...
Matches 1 - 41 out of 41