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7429690 |
Transgenic bovines having reduced prion protein production
The invention provides cloned transgenic ungulates (e.g., bovines) in which prion protein activity is reduced by one or more genetically engineered mutations. Desirably, these transgenic bovines...
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7420099 |
Transgenic animals and uses thereof
In general, the invention features genetically modified non-human mammals (e.g., bovines and other ungulates), and methods of making these mammals. In particular, the invention features transgenic...
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7414170 |
Transgenic bovines capable of human antibody production
The invention features novel methods for the production of large quantities of xenogenous antibodies, such as human antibodies. Preferably, this result is effected by inactivation of IgM heavy...
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7371517 |
High purity X-chromosome bearing and Y-chromosome bearing populations of spermatozoa
Isolated non-naturally occurring populations of spermatozoa ( 15 ) having high purity and technologies to differentiate spermatozoa ( 28 ) based on characteristics such as mass, volume,...
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EP1917974A1 |
Equine system for non-surgical artifical insemination
Non-surgical artificial insemination is achieved for sexed and unsexed equines in a commercially practical manner and with dosages of insemination sperm which were not previously thought to be...
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EP1818391A2 |
Sex-specific insemination of mammals with low number of sperm cells
Artificial Insemination is achieved for sexed mammalian offspring in a commercially practical manner and with dosages of insemination sperm which were not previously thought to be practical for...
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7221453 |
Optical apparatus
Various optical apparatus provide a source of parallel light ( 7, 75 ). The parallel light ( 7, 75 ) is generally achieved by directing an incident beam at the apex of a prism ( 1, 22, 24, 26, 28...
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7208265 |
Method of cryopreserving selected sperm cells
The present invention provides a method of cryopreserving sperm that have been selected for a specific characteristic. In a preferred embodiment, the method is employed to freeze sex-selected...
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7195920 |
Collection systems for cytometer sorting of sperm
Improved flow cytometer system particularly adapted to use for sex-selected sperm sorting include enhanced sheath fluid and other strategies which minimize stress on the sperm cells, including a...
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7169548 |
Sperm cell processing and preservation systems
Methods and apparatus are disclosed for processing sperm cells to accomplish preservation for future use while minimizing the adverse effects of such preservation. Sperm cells may be collected from...
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7094527 |
System for in-vitro fertilization with spermatozoa separated into X-chromosome and Y-chromosome bearing populations
An IVF system for successfully utilizing spermatozoa separated into X-chromosome bearing and into Y-chromosome bearing population for insemination. The IVF system includes fertilization medium that...
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7074983 |
Transgenic bovine comprising human immunoglobulin loci and producing human immunoglobulin
The present invention relates to the production of a transgenic bovine which comprises a genetic modification that results in inactivation and loss of expression of its endogenous antibodies, and...
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6700037 |
Method of cloning porcine animals
The present invention relates to materials and methods for cloning porcine animals. The invention relates in part to totipotent cells useful for cloning porcine animals, porcine embryos produced...
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6603059 |
Method of cloning animals
The present invention relates to cloning technologies. The invention relates in part to immortalized and totipotent cells useful for cloning animals, the embryos produced from these cells using...
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6524860 |
Methods for improving sheath fluids and collection systems for sex-specific cytometer sorting of sperm
Improved flow cytometer system particularly adapted to use for sex-selected sperm sorting include enhanced sheath fluid and other strategies which minimize stress on the sperm cells, including a...
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6518426 |
Pyrimidine derivatives and methods of making and using these derivatives
Novel pyrrolo[3,2-d]pyrimidine derivatives of the following general formula are disclosed. These compounds are useful in the treatment of bacterial infections such as Toxoplasmosis gondii and ...
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6489092 |
Method for sex determination of mammalian offspring
A method for increasing the percentage of mammalian offspring of either sex which comprises contacting a semen sample with an antibody specific for the spermatozoa determinative of one sex and...
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6395958 |
Method of producing a polypeptide in an ungulate
The present invention relates to cloning technologies. The invention relates in part to immortalized and totipotent cells useful for cloning animals, the embryos produced from these cells using...
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6372422 |
Multiple sexed embryo production system for mammals
Improved insemination systems particularly adapted to use for sex-selected sperm sorting include systems which achieve superovulation and then multiple embryo production with sexed embryos. These...
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6258998 |
Method of cloning porcine animals
The present invention relates to materials and methods for cloning porcine animals. The invention relates in part to totipotent cells useful for cloning porcine animals, porcine embryos produced...
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6149867 |
Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
Improved flow cytometer system particularly adapted to use for sex-selected sperm sorting include enhanced sheath fluid and other strategies which minimize stress on the sperm cells, including a...
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5840504 |
Method for separating sex specific molecules and non-sex specific molecules
A method for identifying non-sex specific and sex specific molecules associated with animal cell membranes is described. The method involves preparing a cell membrane fraction from adult, fetal, or...
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5660997 |
Methods for determining antibodies specific for sex associated sperm membrane proteins
Substantially pure sex-associated membrane (SAM) proteins are used in methods to detect specific antibodies binding to X- or Y-SAM proteins.
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5439362 |
Sex-associated membrane proteins and methods for increasing the probability that offspring will be of a desired sex
A method of sorting living cells based on DNA content. Mammalian sperm subpopulations enriched in X- or Y-sperm. X- and Y-enriched sperm-plasma-membrane vesicles. Substantially pure sex-associated...
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