Matches 1 - 50 out of 135 1 2 3 >
Match Document Document Title
7407630 High density plate filler  
A filling apparatus for filling a microplate. The microplate having a plurality of wells each sized to receive an assay. The filling apparatus can comprise an assay input layer having a first...
7336812 System for microvolume laser scanning cytometry  
The present invention provides an improved integrated system for biological marker identification. The system uses Microvolume Laser Scanning Microscopy (MLSC) in order to measure patterns of...
7312919 Wide field of view and high speed scanning microscopy  
A wide field of view scanning microscope includes a light source, a light detector, optics, a scanning assembly, a translation system, and a data collection control and processing unit. The...
7310547 Fluorescent fiberoptic probe for tissue health discrimination  
A system and method for the in situ discrimination of healthy and diseased tissue. A fiberoptic based probe is employed to direct ultraviolet illumination onto a tissue specimen and to collect the...
7309867 Methods and apparatus for characterization of tissue samples  
The invention provides methods for determining the probability that a given region of a tissue sample contains tissue of a given category, such as CIN 1 (cervical intraepithelial neoplasia, grade...
7282723 Methods and apparatus for processing spectral data for use in tissue characterization  
The invention provides methods for processing tissue-derived spectral data for use in a tissue classification algorithm. Methods of the invention comprise application of spectral and/or image masks...
7260248 Image processing using measures of similarity  
The invention provides methods of relating a plurality of images based on measures of similarity. The methods of the invention are useful in the segmentation of a sequence of colposcopic images of...
7259845 Disposable optical cuvette cartridge with low fluorescence material  
A disposable cuvette cartridge for optical measurements is formed from three flexible thin layers. The middle layer is an adhesive sheet with cut out regions, typically between 30 and 50, serving...
7253404 Median filter for liquid chromatography-mass spectrometry data  
High-intensity, spiked noise is reduced in chromatography-mass spectrometry data by applying a nonlinear filter such as a moving median filter to the data. The filter is applied to individual mass...
7248360 Polychronic laser scanning system and method of use  
A system for laser scanning provides spectral flexibility needed for the spectroscopic monitoring of highly multiplexed samples, such as cellular and particle assays in whole blood or other...
EP0965034B1 FLUOROMETRIC DETECTION USING VISIBLE LIGHT  
Abstract not available for EP0965034 Abstract of corresponding document: WO9839636 Systems, devices and methods are provided for viewing a pattern of fluorophors capable of fluorescing when...
7222025 System, method, and product for dynamic noise reduction in scanning of biological material  
Systems and methods are described for processing an emission signal, such as a fluorescent signal, to compensate for noise in an excitation beam, such as a laser beam. As one example, a scanning...
7197401 Peak selection in multidimensional data  
An automatic peak selection method for multidimensional data that selects peaks from very noisy data such as two-dimensional liquid chromatography-mass spectrometry (LC-MS) data is described. Such...
7189361 Analytical device with lightguide Illumination of capillary and microgrooves arrays  
An analytical cell including a lightguide with a plurality of conduits filled with a migration medium. The medium, the lightguide and a surrounding medium have refractive indices selected such that...
7187810 Methods and systems for correcting image misalignment  
The invention provides methods of determining a correction for a misalignment between at least two images in a sequence of images due at least in part to sample movement. The methods are applied,...
7177023 Fluorescent light detection  
System and method for fluorescent light detection from biological samples to enhance the numerical aperture and/or reduce the cross-talk of the fluorescent light.
7169279 Sample handling system for a multi-channel capillary electrophoresis device  
A sample handling system in a multi-channel capillary electrophoresis apparatus is disclosed. The sample handling system includes a work surface for supporting a plurality of samples located at a...
7136518 Methods and apparatus for displaying diagnostic data  
The invention provides methods for displaying diagnostic results obtained from a tissue sample. In general, the invention assigns tissue-class probability values to discrete regions of a patient...
7135667 Array imaging system  
An apparatus for imaging an array of a plurality of features associated with a sample tile. The apparatus can comprise a stage that supports the sample tile in an illumination region, and an...
7127282 Optical methods and systems for rapid screening of the cervix  
A method and a system is provided for discriminating between healthy cervical tissue and pathologic cervical tissue based on the fluorescence response of the tissue to laser excitation (LIF) and...
7103401 Colonic polyp discrimination by tissue fluorescence and fiberoptic probe  
A system and method for the in situ discrimination of healthy and diseased tissue. A fiberoptic based probe is employed to direct ultraviolet illumination onto a tissue specimen and to collect the...
7090758 Capillary array electrophoresis scanner  
An improved rotary confocal fluorescence scanner capable of detecting analytes separated on over a 1,000 capillaries simultaneously. This system uses a confocal microscope objective and mirror...
7056427 Electrophoresis apparatus using capillary array and sample plate assembly used therefor  
A sample plate assembly for an electrophoresis apparatus including a tray at a sample supply portion of a capillary array, an adapter for the tray, a sample plate mounted on the adapter, a septer...
7005052 Capillary array  
A capillary array includes a light detection portion, a sample supply portion, a buffer solution supply portion and a voltage application portion which are necessary functions for electrophoresis,...
6984828 Quantified fluorescence microscopy  
The present invention relates to calibration apparatuses, methods or tools used in microscopy. A calibration tool for fluorescent microscopy includes a support, a solid surface layer including a...
6972183 Capillary array-based enzyme screening  
A process for screening an expression library to identify clones expressing enzymes having a desired activity is provided. The process involves first generating from genomic DNA samples of one or...
EP0773438B1 Automated optical alignment using a galvanometric scanner  
Abstract of EP0773438 The device includes generating device for generating electromagnetic (EM) radiation, EM radiation directing device for directing the electromagnetic radiation to each of the...
6953521 Automated parallel capillary electrophoresis system with hydrodynamic sample injection  
An automated capillary zone electrophoretic system is disclosed. The system employs a capillary cartridge having a plurality of capillary tubes. The cartridge has a first array of capillary ends...
EP0823052B1 A MULTICAPILLARY FLUORESCENT DETECTION SYSTEM  
Abstract not available for EP0823052 Abstract of corresponding document: US5675155 A detection system for sequentially and repetitively scanning a plurality of sample volumes and detecting...
6936152 Capillary array electrophoresis apparatus and method of separating and analyzing specimen  
At a wall constituting a space for a thermostatic oven in an electrophoresis apparatus, a capillary array attachment portion is formed which permits attachment of a plurality of capillary arrays...
6933154 Optimal windows for obtaining optical data for characterization of tissue samples  
The invention provides methods for determining a characteristic of a tissue sample, such as a state of health, using spectral data and/or images obtained within an optimal period of time following...
6914250 Fluorometric detection using visible light  
Systems, devices and methods of the present invention are for viewing a pattern of fluorophors capable of fluorescing when exposed to visible light, e.g., fluorescently stained DNA, protein or...
6902935 Methods of monitoring effects of chemical agents on a sample  
The invention provides methods and systems for monitoring effects of chemical agents on optical signals produced by samples in response to the chemical agents. Preferred methods comprise...
6881312 Ultra high throughput microfluidic analytical systems and methods  
Analytical systems and methods that use a modular interface structure for providing an interface between a sample substrate and an analytical unit, where the analytical unit typically has a...
6866824 Capillary array-based sample screening  
Provided are methods of screening and identification of bioactivities and bioactive molecules of interest using a capillary array system. More specifically, disclosed are methods of using optical...
6847490 Optical probe accessory device for use in vivo diagnostic procedures  
The present invention recognizes that optical probes function both as medical access devices and as instruments which collect complex optical data. The invention provides an optical probe accessory...
6839661 System for normalizing spectra  
A method and system for normalizing optical spectra using a non-uniform segment normalization. A spectrum is obtained and is represented as a function of wavelength as an amplitude at each of a...
6826422 Spectral volume microprobe arrays  
Methods and apparatus are provided for determining a characteristic of a sample of a material by the interaction of electromagnetic radiation with the sample. The apparatus includes an optical...
6818903 Method and apparatus for identifying spectral artifacts  
The invention provides an apparatus and methods for determining whether spectral data obtained from a region of a tissue sample are affected by an artifact. Artifacts include, for example, lighting...
6813567 System, method, and product for dynamic noise reduction in scanning of biological materials  
Systems and methods are described for processing an emission signal, such as a fluorescent signal, to compensate for noise in an excitation beam, such as a laser beam. As one example, a scanning...
6805784 Capillary array  
The structure of a capillary head section is made such that the liquid contacting surfaces of a capillary holder, a capillary, and an adhesive form a plane surface, and this shared liquid...
6800438 Imager for DNA sequencer  
An improved method for the sequencing of DNA fragments is provided. The method includes using a known process for DNA fragment separation, such as capillary electrophoresis, and imaging the...
6799629 Cooling apparatus for a multiplexed capillary electrophoresis system  
Apparatus for cooling a bundle of capillary tubes to prevent overheating of the tubes during a parallel capillary electrophoresis procedure. The apparatus includes a jacket of thermally conductive...
6794127 Capillary array-based sample screening  
Provided are methods of screening and identification of bio activities and bioactive molecules of interest using a capillary array system. More specifically, disclosed are methods of using optical...
6787111 Apparatus and method for filling and cleaning channels and inlet ports in microchips used for biological analysis  
An apparatus for filling and cleaning channels and inlet ports of a microchip substrate is disclosed. A device of the apparatus comprising an array of tubes is inserted into each of the inlet ports...
6768918 Fluorescent fiberoptic probe for tissue health discrimination and method of use thereof  
A system and method for the in situ discrimination of healthy and diseased tissue. A fiberoptic based probe is employed to direct ultraviolet illumination onto a tissue specimen and to collect the...
6764648 Robotic microchannel bioanalytical instrument  
A substrate with a plurality of microchannels is movably deployed with other movable objects that will load sample into the microchannels, stimulate molecular migration, read the results of the...
6760613 Substantially monostatic, substantially confocal optical systems for examination of samples  
The present invention relates to systems and methods for examining a sample using a substantially monostatic, substantially confocal optical system comprising transmitting optics that focus an...
6750457 System for high throughput analysis  
An apparatus and method in which illumination light and collected emitted light share a pathway and subsequently are physically separated. The optical configuration is designed such that at the...
6740219 Electrophoresis analysis apparatus and sample vessel used therefor  
A multi-capillary type electrophoresis analysis apparatus has a sample tray for containing a plurality of samples, wherein part of the sample tray is made from a conductive material. Samples are...
Matches 1 - 50 out of 135 1 2 3 >