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7381315 Multi-channel analyte-separation device employing side-entry excitation  
A side-entry excitation arrangement is provided with a multi-channel analyte-separation device. In various embodiments, a plurality of channels are disposed in an array, with a laser disposed to...
7309409 Multi-channel bio-separation cartridge  
A bio-separation system using an efficient, compact, portable, interchangeable, reusable, recyclable, multi-channel cartridge, has integrated pre-aligned optics and an integrated reagent reservoir....
7280207 Time-delay integration in a flow cytometry system  
An apparatus for detecting analytes in a sample is provided. The apparatus can include: a flow cytometry system including one or more detection zones; one or more irradiation sources disposed for...
7265833 Electrophoretic system with multi-notch filter and laser excitation source  
Apparatus and methods for detecting analytes in a sample are provided. The apparatus can include: one or more channels having a detection zone; one or more irradiation sources disposed for...
7214300 Integrated electrokinetic devices and methods of manufacture  
Devices with electrokinetic elements are disclosed as well as their method of microfabrication for use in micro-scale analysis, mixture separation and reaction. The devices consist of solid...
7208072 Multi-segment cartridge for bio-separation with multiplexed fluorescence detection  
A bio-separation instrument using a multi-segment cartridge. The cartridge includes a plurality of efficient, compact, portable, interchangeable, reusable, recyclable, modular, multi-channel...
7112266 Multi channel capillary electrophoresis device and method  
Embodiments of a device and method are described which provide for control over the distortion of a sample zone upon exiting an electrophoresis separation channel. According to the teachings herein...
7019831 Separation device substrate including non-fluorescent quencher dye  
A device is provided for the analysis of samples. The device includes a plurality of sample-containment features and a non-fluorescent quenching material for minimizing cross-talk between optical...
7018520 Concentration and cleanup of nucleic acid samples  
Methods and devices are described for concentration and cleanup of samples containing bio-molecule analytes (e.g., polynucleotides, such as DNA, RNA, PNA). Various embodiments provide for...
RE38817 Method and system for velocity-normalized position-based scanning  
A data collection method for scanning a scan window comprising one or more channels is described. In the method of the invention an integrated signal (S) is measured across a scan window including...
6896778 Electrode module  
Planar devices incorporating electrodes for performing chemical analyses are disclosed. The devices include an electrode module in a fluidic housing. The electrode module includes a carrier module...
6856390 Time-delay integration in electrophoretic detection systems  
An apparatus for detecting analytes in a sample is provided. The apparatus includes: one or more channels having a detection zone; one or more irradiation sources disposed for irradiating the...
6846398 Device and method for miniaturized, highly parallel electrophoretic separation  
In an electrophoresis device with numerous separation channels S loadable with samples, samples are loaded by applying samples in a shared injection channel I intersecting the separation channels S...
6627433 Multi-channel analyte-separation device employing side-entry excitation  
A side-entry excitation arrangement is provided with a multi-channel analyte-separation device. In various embodiments, a plurality of channels are disposed in an array, with a laser disposed to...
6596140 Multi-channel capillary electrophoresis device and method  
Embodiments of a device and method are described which provide for control over the distortion of a sample zone upon exiting an electrophoresis separation channel. According to the teachings herein...
6592733 Capillary electrophoresis devices incorporating optical waveguides  
A capillary electrophoresis device having a substrate layer and a cover layer, with a plurality of electrophoresis channels formed in the substrate layer, includes an optical waveguide system that...
6576108 DNA detector and DNA detection method  
An electrophoresis apparatus includes an optical cell having an outlet for fluid and filled with a buffer solution, and a plurality of electrophoresis lanes, each including a separation medium,...
6485625 Apparatus and method for the generation, separation, detection, and recognition of biopolymer fragments  
This invention is an integrated instrument for the high-capacity electrophoretic analysis of biopolymer samples. It comprises a specialized high-voltage, electrophoretic module in which the...
6475361 Capillary electrophoresis apparatus having filling/refilling system and methods for use thereof  
The present invention relates to an electrophoresis apparatus having a filling/refilling system and methods of using the same. The electrophoresis apparatus comprises a first buffer chamber...
6427126 Automatic sequencer/genotyper having extended spectral response  
An advanced imaging spectrograph system and method are provided for very high throughput identification, sequencing and/or genotyping of DNA and other molecules. The system is based on the...
EP1109014A2 Multiplexed capillary electrophoresis system  
The invention provides an array (2) of capillaries (1) with a two-dimensional image array detector (21) optically coupled thereto to detect fluorescent light emitted by target species introduced...
6236945 Apparatus and method for the generation, separation, detection, and recognition of biopolymer fragments  
This invention is an integrated instrument for the high-capacity electrophoretic analysis of biopolymer samples. It comprises a specialized high-voltage, electrophoretic module in which the...
6224733 DNA detector and DNA detection method  
An electrophoresis apparatus includes a plurality of capillaries through which samples labeled with a plurality of fluorophores migrate, a pair of electrodes which generate an electric field which...
6218121 Apparatus and method for the generation, separation, detection, and recognition of biopolymer fragments  
This invention is an integrated instrument for the high-capacity electrophoretic analysis of biopolymer samples. It comprises a specialized high-voltage, electrophoretic module in which the...
6156177 DNA detector and DNA detection method  
A method for analyzing samples includes the steps of introducing samples labeled with fluorophores into a first end of each of a plurality of electrophoresis lanes including a separation medium, a...
6132578 Method and apparatus for electrophoresis separation and detection  
An electrophoresis separation and detection apparatus for separating and detecting fluorophore-labeled samples by electrophoresis, which comprises a migrating and separating means for...
6103083 Capillary electrophoresis apparatus and method  
The present invention relates to an electrophoresis apparatus having a plurality of capillaries arranged in a plane such that a curving contour is formed by the intersection points of each of the...
6054036 Electrophoresis gels and gel holders having fiber spacers and method of making same  
Gel holders for electrophoresis gels are made using clad fibers, particularly glass fibers as spacers between substrates. A plurality of fibers with a high-melting interior core and a low-melting...
6040586 Method and system for velocity-normalized position-based scanning  
A data collection method for scanning a scan window comprising one or more channels is described. In the method of the invention an integrated signal (S) is measured across a scan window including...
6017434 Apparatus and method for the generation, separation, detection, and recognition of biopolymer fragments  
This invention is an integrated instrument for the high-capacity electrophoretic analysis of biopolymer samples. It comprises a specialized high-voltage, electrophoretic module in which the...
6007689 Apparatus for preparing gels for use in electrophoretic separations and similar applications  
An apparatus for the rapid preparation of electrophoresis gels comprises: (a) a housing; (b) a support fixture removably disposed within the housing and adapted to receive a gel holder having an...
5993634 Apparatus and method for the generation, separation, detection, and recognition of biopolymer fragments  
This invention is an integrated instrument for high-capacity electrophoretic analysis of biopolymer samples. It comprises a specialized high-voltage, electrophoretic module in which the migration...
5968331 Sample holding device for electrophoresis apparatus and sample injection method  
A sample holding device for electrophoresis apparatus according to the present invention wherein a plurality of sample holding capillaries are laid out in an array and are immobilized to the...
5885431 Microgels for use in medical diagnosis and methods of making and using same  
An electrophoresis microgel is formed in a gel holder. The gel holder comprises a top substrate, a bottom substrate and a spacer disposed between the top substrate and the bottom substrate. The...
5871628 Automatic sequencer/genotyper having extended spectral response  
An advanced imaging spectrograph system provides for slab-gel DNA sequencing and genotyping with high throughput sequencing. The system is based on the integration of improved electrophoresis...
5858194 Capillary, interface and holder  
A capillary, interface and holder for a capillary electrophoresis system are provided herein. The capillary is disposed in a substantially planar housing having side surfaces. The capillary...
EP0840800A1 APPARATUS AND METHOD FOR THE GENERATION, SEPARATION, DETECTION, AND RECOGNITION OF BIOPOLYMER FRAGMENTS  
Abstract not available for EP0840800 Abstract of corresponding document: US6017434 This invention is an integrated instrument for the high-capacity electrophoretic analysis of biopolymer samples....
5746901 Hybrid slab-microchannel gel electrophoresis system  
A hybrid slab-microchannel gel electrophoresis system. The hybrid system permits the fabrication of isolated microchannels for biomolecule separations without imposing the constraint of a totally...
5741412 Multiple capillary biochemical analyzer  
A multiple capillary analyzer allows detection of light from multiple capillaries with a reduced number of interfaces through which light must pass in detecting light emitted from a sample being...
5741411 Multiplexed capillary electrophoresis system  
The invention provides a side-entry optical excitation geometry for use in a multiplexed capillary electrophoresis system. A charge-injection device is optically coupled to capillaries in the array...
5717602 Automated electrophoresis and analysis system  
An automated electrophoresis apparatus defining an enclosure that receive a sample gel containing sample material. A voltage is applied to the sample gel and the material migrates through the...
5707506 Channel plate for DNA sequencing  
This invention is a channel plate that facilitates data compaction in DNA sequencing. The channel plate has a length, a width and a thickness, and further has a plurality of channels that are...
5654636 Method and apparatus for NMR spectroscopy of nanoliter volume samples  
A method and apparatus for structural elucidation and determination of a nanoliter size sample of analyte. The method includes separating the analyte using a microseparation technique and then...
5636017 Optical detection arrangement for small volume chemical analysis of fluid samples  
An optical detection arrangement for small volume chemical analysis comprises a light source (22), a capillary tube (23) and a photoelectric detector (24). The arrangement of the light source (22)...
5628891 Electrophoresis device  
An electrophoresis gel carrier includes end mounts, each having a buffer well and retainer elements constructed to support an electrophoresis medium gel so that the gel is in communication with the...
5627022 Microgels for use in medical diagnosis and holders useful in fabricating same  
An electrophoresis microgel is formed in a gel holder. The gel holder comprises a top substrate, a bottom substrate and a spacer disposed between the top substrate and the bottom substrate. The...
5618398 Electrophoresis gels and gel holders having fiber spacers and method of making same  
Gel holders for electrophoresis gels are made using clad fibers, particularly glass fibers as spacers between substrates. A plurality of fibers with an high-melting interior core and a low-melting...
5599434 Electrophoresis gels and gel holders having adhesive affixed fiber spacers and method of making same  
Gel holders for electrophoresis gels are made using fibers, particularly glass fibers, which are affixed to the substrates forming the gel holder using an adhesive. These gel holders can be made by...
5584982 Multiple capillary biochemical analyzer  
A multiple capillary analyzer allows detection of light from multiple capillaries with a reduced number of interfaces through which light must pass in detecting light emitted from a sample being...
5543026 Real-time scanning fluorescence electrophoresis apparatus for the analysis of polynucleotide fragments  
This invention relates to an improved real-time scanning fluorescence electrophoresis apparatus for the electrophoretic analysis of fluorescently-labeled polynucleotide fragments. The apparatus is...
Matches 1 - 50 out of 56 1 2 >