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7315357 |
Imaging and analyzing parameters of small moving objects such as cells
Light from an object such as a cell moving through an imaging system is collected and dispersed so that it is imaged onto a plurality of separate detectors. The light is spectrally dispersed by a...
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7303922 |
Reagentless analysis of biological samples by applying mathematical algorithms to smoothed spectra
Apparatus and method for determining at least one parameter, e. g., concentration, of at least one analyte, e. g., urea, of a biological sample, e. g., urine. A biological sample particularly...
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7286719 |
Method and apparatus for correcting crosstalk and spatial resolution for multichannel imaging
A multi-channel imaging system generates an ensemble of images for each field of view of an object. Each image in the ensemble is intended to contain information from only one source among a...
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7221457 |
Imaging platform for nanoparticle detection applied to SPR biomolecular interaction analysis
A flow imaging system is used to implement surface plasmon resonance (SPR) detection to study bio-molecular interactions. The flow imaging system is used to capture SPR absorption spectra of large...
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7190832 |
Computational methods for the segmentation of images of objects from background in a flow imaging instrument
In automated computation-based interpretation of images, the accuracy and reliability of the detection and delineation of objects, known as “object segmentation,” is implemented so as to...
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7087877 |
Auto focus for a flow imaging system
A pair of optical gratings are used to modulate light from an object, and the modulated light from either grating is used to determine the velocity of the object. Each optical grating is offset...
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7079708 |
Method and apparatus for correcting crosstalk and spatial resolution for multichannel imaging
A multichannel imaging system generates an ensemble of images for each field of view of an object. Each image in the ensemble is intended to contain information from only one source among a...
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7057732 |
Imaging platform for nanoparticle detection applied to SPR biomolecular interaction analysis
A flow imaging system is used to implement surface plasmon resonance (SPR) detection to study bio-molecular interactions. The flow imaging system is used to capture SPR absorption spectra of large...
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7034317 |
Method and apparatus for limiting scanning imaging array data to characteristics of interest
A method and system for limiting the amount of image data to be captured by a scanning imaging array. A low-resolution preliminary image of an object is acquired. Data from the preliminary image is...
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7006710 |
Method and apparatus for correcting crosstalk and spatial resolution for multichannel imaging
A multichannel imaging system generates an ensemble of images for each field of view of an object. Each image in the ensemble is intended to contain information from only one source among a...
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6975400 |
Imaging and analyzing parameters of small moving objects such as cells
Light from an object such as a cell moving through an imaging system is collected and dispersed so that it is imaged onto a plurality of separate detectors. The light is spectrally dispersed by a...
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6947136 |
Multipass cavity for illumination and excitation of moving objects
An illumination system for increasing a light signal from an object passing through a reflection cavity. The reflection cavity is defined by spaced-apart, opposed first and second surfaces disposed...
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6947128 |
Alternative detector configuration and mode of operation of a time delay integration particle analyzer
Light from an object moving through an imaging system is collected, dispersed, and imaged onto a time delay integration (TDI) detector that is inclined relative to an axis of motion of the object,...
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6934408 |
Method and apparatus for reading reporter labeled beads
Combinatorially-synthesized deoxyribonucleic acid (DNA) oligonucleotides attached to encoded beads that are hybridized to amplified and labeled genomic DNA or ribonucleic acid (RNA) are analyzed...
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6906792 |
Methods of calibrating an imaging system using calibration beads
When utilized in a flow imaging instrument, calibration beads provide a known data source that can be employed in various self-diagnostic, calibration and quality metric applications for the both...
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6875973 |
Auto focus for a flow imaging system
A pair of optical gratings are used to modulate light from an object, and the modulated light from either optical is used to determine the velocity of the object. Each optical grating is offset...
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6773922 |
Reagentless analysis of biological samples
Apparatus and method for determining at least one parameter, e.g., concentration, of at least one analyte, e.g., urea, of a biological sample, e.g., urine. A biological sample particularly suitable...
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6707551 |
Multipass cavity for illumination and excitation of moving objects
An illumination system for increasing a light signal from an object passing through a reflection cavity. The reflection cavity is disposed between spaced-apart, opposed first and second surfaces...
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6671044 |
Imaging and analyzing parameters of small moving objects such as cells in broad flat flow
Light from an object such as a cell moving through an imaging system is collected and dispersed so that it can be imaged onto a time delay and integration (TDI) detector. The light can be emitted...
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6608682 |
Imaging and analyzing parameters of small moving objects such as cells
Light from an object such as a cell moving through an imaging system is collected and dispersed so that it is imaged onto a plurality of separate detectors. The light is spectrally dispersed by a...
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6608680 |
TDI imaging system for kinetic studies
Light from an object such as a cell moving through an imaging system is collected, and imaged onto a time delay integration (TDI) detector, producing a pixelated output signal in response to the...
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6583865 |
Alternative detector configuration and mode of operation of a time delay integration particle analyzer
Light from an object moving through an imaging system is collected, dispersed, and imaged onto a time delay integration (TDI) detector that is inclined relative to an axis of motion of the object,...
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6580504 |
Multipass cavity for illumination and excitation of moving objects
An illumination system for increasing a light signal from an object passing through a reflection cavity. The reflection cavity is disposed between spaced-apart, opposed first and second surfaces...
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6563583 |
Multipass cavity for illumination and excitation of moving objects
A multipass cavity system employs a beam of light that is reflected back and forth between reflective surfaces a plurality of times, illuminating a different portion of the field of view with each...
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6532061 |
Measuring the velocity of small moving objects such as cells
Frequency domain velocity measurements and time domain velocity measurements are made using light from cells or other objects. An optical grating is used to modulate the light from an object so...
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6507391 |
Measuring the velocity of small moving objects such as cells
Frequency domain velocity measurements and time domain velocity measurements are made using light from cells or other objects. An optical grating is used to modulate the light from an object so...
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6473176 |
Imaging and analyzing parameters of small moving objects such as cells
Light from an object such as a cell moving through an imaging system is collected and dispersed so that it can be imaged onto a detector. The light can be emitted from a luminous object or can be...
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6426045 |
Reagentless analysis of biological samples
Apparatus and method for determining at least one parameter, e. g., concentration, of at least one analyte, e. g., urea, of a biological sample, e. g., urine. A biological sample particularly...
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6365109 |
Reagentless analysis of biological samples
Apparatus and method for determining at least one parameter, e.g., concentration, of at least one analyte, e.g., urea, of a biological sample, e.g., urine. A biological sample particularly suitable...
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6317511 |
Method and apparatus for particle image analysis using flow cell
A sample is flowed through a flow cell, the passage of particles is detected by a laser light beam, a flash lamp is turned on in response to the detection, still images of the particles are picked...
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6249341 |
Imaging and analyzing parameters of small moving objects such as cells
Light from an object such as a cell moving through an imaging system is collected and dispersed so that it can be imaged onto a time delay and integration (TDI) detector. The light can be emitted...
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6211955 |
Imaging and analyzing parameters of small moving objects such as cells
Light from an object such as a cell moving through an imaging system is collected and dispersed so that it can be imaged onto a time delay and integration (TDI) detector. The light can be emitted...
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6087182 |
Reagentless analysis of biological samples
Apparatus and method for determining at least one parameter, e. g., concentration, of at least one analyte, e. g., urea, of a biological sample, e.g, urine. A biological sample particularly...
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5880835 |
Apparatus for investigating particles in a fluid, and a method of operation thereof
In order to investigate particles in a fluid, a flow cell causes the fluid to flow past a sensor which receives light from a continuous light emission system. When the sensor detects a change in...
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5790246 |
Apparatus and network for determining a parameter of a particle in a fluid employing detector and processor
An apparatus and method for determining a parameter of a particle in a fluid is disclosed and, in particular, an apparatus and method for determining contamination or machine wear by the...
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5786894 |
Measurement of paper pulp and fiber visual characteristics
A system for determining characteristics of objects in wood pulp includes a pulp sampling and dilution system for diluting and dispersing samples of pulp, and an imaging/analysis system for...
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5548395 |
Particle analyzer
A particle analyzer comprising a one-dimensional image sensor for producing imaging signals by scanning a particle in a flow of specimen containing particle components such as blood and urine in a...
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5469251 |
Apparatus for detecting fluorescence of particles in a fluid and analyzing the particles
An apparatus for analyzing particles at high precision capable of obtaining informations in real time such as morphological informations and fluorescence image of cells (particles) contained in a...
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5444527 |
Imaging flow cytometer for imaging and analyzing particle components in a liquid sample
An imaging flow cytometer for capturing images and, analyzing particle components in a liquid sample containing particle components such as blood and urine, or microparticles such as organic high...
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5422712 |
Apparatus for measuring fluorescent spectra of particles in a flow
A sample liquid flow containing particle components such as blood and urine is illuminated with light, and signals from particles are detected, and the particles are thereby analyzed. In this...
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