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EP1953235A2 |
New genes related to a process for the production of fine chemicals
The present invention relates to a process for the production of the fine chemical in a microorganism, a plant cell, a plant, a plant tissue or in one or more parts thereof. The invention...
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EP1950297A2 |
Compositions and methods for treating neoplastic disease using chemotherapy and radiation sensitizers
Inhibitors of KIAA0175 are provided that reduce the expression or biological activities of KIAA0175, p53 and/or p21 in a mammalian cell. KIAA0175 inhibitors include anti-sense molecules, ribozymes,...
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EP1925671A1 |
Flax (Linum usitatissimum L.) seed-specific promoters
The present invention is directed to promoters of flax conlinin and ro-3 desaturase genes. The promoters guide high levels of the expression exclusively in flax developing seeds. This specific...
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7378243 |
Nucleic acid cloning
The present invention provides an improved system for linking nucleic acids to one another. In particular, the present invention provides techniques for producing DNA product molecules that may be...
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EP1900816A2 |
GL50 molecules and uses therefor
The invention provides isolated nucleic acids molecules, designated GL50 nucleic acid molecules, which encode GL50 polypeptides. The invention also provides antisense nucleic acid molecules,...
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EP1900749A1 |
Nucleic acids for expressing a polynucleotide of interest in mammalian cancer cells
The invention relates to regulatory polynucleotides derived (i) from rat and human AFP promoter sequences and (ii) from rat and human HIP/PAPI promoter sequences, which regulatory polynucleotides...
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7342111 |
Adeno-associated virus-delivered ribozyme compositions and methods of use
Provided are methods for the identification of novel genes involved in a variety of cellular processes, including retinal degeneration, retinal disease, cancer, memory and learning, amylotropic...
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EP1881073A2 |
Phosphatase stress-related protein and methods of use in plants
A transgenic plant transformed by a phosphatase stress-related protein (PHSRP) coding nucleic acid, wherein expression of the nucleic acid sequence in the plant results in increased tolerance to...
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EP1852507A1 |
CRSP protein (cysteine-rich secreted proteins), nucleic acid molecules encoding them and uses therefor
CRSP (Cysteine-Rich Secreted Proteins) polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length CRSP proteins, the invention further provides isolated...
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EP1852123A2 |
Activation and inhibition of the immune system
Induction of an anergic response by NF-κB inhibitors and the inhibition of immune response by the administration of an inhibitor of NF-κB is disclosed. Examples ofNF-κB inhibitors include...
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EP1842918A1 |
Receptor nucleic acids and polypeptides
Disclosed are nucleic acids encoding BAFF-R polypeptides, as well as antibodies to BAFF-R polypeptides and pharmaceutical compositions including same. Methods of treating tumorigenic and autoimmune...
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7265264 |
Gene for a Dof transcription factor capable of altering the size and stature of a plant
A transgenic plant transformed by a Dof transcription factor, OBP3, coding nucleic acid, wherein expression of the nucleic acid sequence in the plant results in an alteration in the size of the...
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EP1820495A2 |
Microspheres for active embolization
The present invention relates to injectable compositions comprising biocompatible, swellable, substantially hydrophilic, non-toxic and substantially spherical polymeric material carriers which are...
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EP1798239A2 |
G-protein coupled receptors and uses therefor
The invention provides isolated nucleic acids molecules, designated flh84g5 nucleic acid molecules, which encode polypeptides having high sequence homology to G-protein coupled receptors. The...
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EP1797754A1 |
Transcription factor stress-related proteins and methods of use in plants
A transgenic plant transformed by a transcription factor stress-related protein (TFSRP) coding nucleic acid, wherein expression of the nucleic acid sequence in the plant results in increased...
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EP1795600A2 |
Cell cycle stress-realted proteins and methods of use in plants
A transgenic plant transformed by a Cell Cycle Stress-Related Protein (CCSRP) coding nucleic acid, wherein expression of the nucleic acid sequence in the plant results in increased tolerance to...
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EP1792913A1 |
Novel secreted and membrane-associated proteins and uses therefor
Novel secreted and membrane-associated polypeptides, proteins, and nucleic acid molecules are disclosed (e.g., BDSF and STMST molecules). In addition to isolated, full-length proteins, the...
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EP1792912A2 |
Novel proteins and nucleic acids encoding same
The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small...
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EP1790728A2 |
Imaging, diagnosis and treatment of disease
The present invention relates to endothelial cell-specific genes and encoded polypeptides and materials and uses thereof in the imaging, diagnosis and treatment of conditions involving the vascular...
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EP1790727A2 |
Proteins and nucleic acids encoding same
Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to...
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EP1790725A2 |
Proteins named after FCTRX and nucleic acids encoding same
Disclosed herein are novel human nucleic acid sequences which encode polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies which...
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EP1783229A2 |
GTP binding stress-related proteins and methods of use in plants
A transgenic plant transformed by a GTP Binding Stress-Related Protein (GBSRP) coding nucleic acid, wherein expression of the nucleic acid sequence in the plant results in increased tolerance to...
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EP1783221A1 |
Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor
Compositions and methods are provided for producing adenine nucleotide translocator (ANT) polypeptides and fusion proteins, including the production and use of recombinant expression constructs...
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EP1772517A2 |
DSP-3 dual specificity phosphatase
Compositions and methods are provided for the treatment of conditions associated with cell proliferation, cell differentiation and cell survival. In particular, the dual-specificity phosphatase...
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7192736 |
Nucleic acid molecules encoding cytotoxic conjugates that contain a chemokine receptor targeting agent
Nucleic acid moleucles that encode conjugates containing as a ligand a chemokine receptor targeting agent, such as a chemokine, and a targeted agent, such as a toxin are provided. These conjugates...
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EP1760146A2 |
Protein kinase stress-related proteins and methods of use in plants
A transgenic plant transformed by a Protein Kinase Stress-Related Protein (PKSRP) coding nucleic acid, wherein expression of the nucleic acid sequence in the plant results in increased tolerance to...
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EP1760145A2 |
Signal transduction stress-related proteins and methods of use in plants
A transgenic plant transformed by a Signal Transduction Stress-Related Protein (STSRP) coding nucleic acid, wherein expression of the nucleic acid sequence in the plant results in increased...
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EP1757618A2 |
ANGIOGENESIS-ASSOCIATED PROTEINS, AND NUCLEIC ACIDS ENCODING THE SAME
There is provided an isolated polypeptide having at least 80% sequence identity to the sequence of SEQ ID NOs: 2, 4, 6, 8, 10, 12, 14 or 16, and polynucleotides encoding the same, which are useful...
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7183458 |
Δ6 acetylenase and Δ6-desaturase from ceratodon purpureus
The present invention relates to a process for preparing unsaturated fatty acids and to a process for preparing triglycerides with an increased content of unsaturated fatty acids. The invention...
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7166702 |
Cytotoxic conjugates comprising a chemokine receptor targeting agent
Conjugates containing as a ligand chemokine receptor targeting agents, such as chemokines, and a targeted agent, such as a toxin are provided. These conjugates are used to treat inflammatory...
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7157418 |
Methods and compositions for treating secondary tissue damage and other inflammatory conditions and disorders
Conjugates containing as a ligand a chemokine receptor targeting agents, such as chemokines, and a targeted agent, such as a toxin are provided. These conjugates are used to treat inflammatory...
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7153685 |
Tamoxifen and 4-hydroxytamoxifen-activated system for regulated production of proteins in eukaryotic cells
Novel tamoxifen inducible and ICI 182,780 repressible expression systems comprising mutant estrogen receptors and mutant estrogen response element are disclosed. Such systems have a wide variety of...
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EP1728870A2 |
Transcription factor stress-related proteins and methods of use in plants
A transgenic plant transformed by a Transcription Factor Stress-Related Protein (TFSRP) coding nucleic acid, wherein expression of the nucleic acid sequence in the plant results in increased...
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7144711 |
AGS proteins and nucleic acid molecules and uses therefor
A screening assay in yeast is disclosed wherein G-protein coupled-receptor independent activators and inhibitors of the pheromone pathway can be identified using a mammalian cDNA library. Novel...
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EP1726652A2 |
Delta 6-desaturases from primulaceae, expressing plants and PUFA-containing oils
The present invention relates to an improved method for the specific production of unsaturated ω-3 fatty acids and a method for the production of triglycerides having an increased content of...
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7141549 |
Proteins and nucleic acids encoding same
Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to...
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EP1714661A2 |
Methods for diagnosing and treating hemostatic disorders by modulating p-selectin activity
The present invention relates to the use of a soluble P-selectin polypeptide, or to an inducer of P-selectin activity, for the preparation of a medicament for the treatment of a...
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EP1702980A1 |
Corynebacterium glutamicum gene encoding Hpr of phosphoenolpyruvate:sugar phosphotransferase system
Isolated nucleic acid molecules, designated PTS nucleic acid molecules, which encode novel PTS proteins from Corynebacterium glutamicum are described. The invention also provides antisense...
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7101973 |
β-amyloid peptide-binding proteins and polynucleotides encoding the same
Novel proteins which bind human β-amyloid peptide, polynucleotides which encode these proteins, and methods for producing these proteins are provided. Diagnostic, therapeutic, and screening...
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7041817 |
Synthesis, deprotection, analysis and purification of RNA and ribozymes
Method for purification and synthesis of RNA molecules and enzymatic RNA molecules in enzymatically active form.
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7005295 |
β-amyloid peptide-binding proteins and polynucleotides encoding the same
Novel proteins which bind human β-amyloid peptide, polynucleotides which encode these proteins, and methods for producing these proteins are provided. Diagnostic, therapeutic, and screening...
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6974684 |
Therapeutic polypeptides, nucleic acids encoding same, and methods of use
Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies,...
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6964849 |
Proteins and nucleic acids encoding same
Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to...
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6916653 |
Ribozymal nucleic acid
A vector system which can be incorporated in liposomes, comprising at least one DNA vector, the vector or vectors containing a target-cleaving hammerhead ribozymal DNA sequence under control of a...
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6803194 |
Use of ribozymes for functionating genes
Double stranded DNAs, expression vectors and methods for their use are provided in which the intracellular expression of the double stranded DNAs is used to alter the phenotype of a target cell so...
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6746852 |
AGS proteins and nucleic acid molecules and uses thereof
The invention provides isolated AGS nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, including AGS specific promoters, host cells into...
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6733991 |
AGS proteins and nucleic acid molecules and uses therefor
A screening assay in yeast is disclosed wherein G-protein coupled-receptor independent activators and inhibitors of the pheromone pathway can be identified using a mammalian cDNA library. Novel...
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6649751 |
Synthesis, deprotection, analysis and purification of RNA and ribozymes
Provided is a method for purification and synthesis of RNA molecules that have at least one chemical modification.
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6551618 |
Compositions and methods for delivery of agents for neuronal regeneration and survival
Devices useful in the delivery of DNA encoding neurotrophic agents, anti-fibrotic agents, and related compositions are disclosed herein for use in the treatment of central and/or peripheral nervous...
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6469158 |
Synthesis, deprotection, analysis and purification of RNA and ribozymes
Method for purification and synthesis of RNA molecules and enzymatic RNA molecules in enzymatically active form.
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