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7396509 Instrument for detecting light emitted by the contents of a reaction receptacle  
An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples...
7384600 Multiple ring assembly for providing specimen to reaction receptacles within an automated analyzer  
An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples...
7373968 Method and apparatus for manipulating an organic liquid sample  
A lid for a well plate, which has pins that penetrate the lid and project downwardly into the wells of the well plate. Thermal energy is applied to the upper end of the pin to regulate the...
7371366 GlcNAc phosphotransferase of the lysosomal targeting pathway  
The present invention provides nucleotide and amino sequences of the lysosomal targeting pathway enzyme GlcNAc-phosphotransferase, methods of producing and methods of purifying this enzyme.
D564667 Rotatable sample processing disk  
7323660 Modular sample processing apparatus kits and modules  
Modular sample processing apparatus kits that can provide a user with the flexibility to customize a disk-based assay in view of a variety of factors are disclosed. The sample processing apparatus...
7273749 Container for carrying out and monitoring biological processes  
A thermal cycling method and device is disclosed. The device comprises a sample chamber whose temperature can be rapidly and accurately modulated over a range of temperatures needed to carry out a...
7267795 Incubator for use in an automated diagnostic analyzer  
An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations, or modules, in which discrete aspects of the assay are performed on fluid samples...
7238321 Method for rapid thermal cycling of biological samples  
A thermal cycling method and device is disclosed. The device comprises a sample chamber whose temperature can be rapidly and accurately modulated over a range of temperatures needed to carry out a...
EP1121200B1 STRUCTURE AND METHOD FOR AUTOMATIC ANALYSIS OF SAMPLES  
Abstract not available for EP1121200 Abstract of corresponding document: WO0021668 A method of performing a determination of an item of interest in a sample using a single structure is disclosed....
7135322 Expression of lysosomal hydrolase in cells expressing pro-N-acetylglucosamine-1-phosphodiester α-N-acetyl glucosimanidase  
The present invention provides methods of producing a pro-N-acetylglucosamine-1-phosphodiesterαN-acetyl glucosimanidase (phosphodiester α-GlcNAcase), in mammalian cells deficient in the furin...
7097968 Methods and compositions for assaying homocysteine  
This invention relates generally to the field of homocysteine detection. In particular, the invention provides a method for determining homocysteine presence or concentration in samples, which...
7081226 System and method for fluorescence monitoring  
A thermal cycling method and device is disclosed. The device comprises a sample chamber whose temperature can be rapidly and accurately modulated over a range of temperatures needed to carry out a...
7074367 Thermostated block with heat-regulating devices  
The invention concerns a thermostated block for laboratory thermostats and comprising wells at a wells side to receive and make large-area contact with the parts of vials filled with sample liquids...
7067127 GIcNAc phosphotransferase of the lysosomal targeting pathway  
The present invention provides nucleotide and amino sequences of the lysosomal targeting pathway enzyme GlcNAc-phosphotransferase, methods of producing and methods of purifying this enzyme.
7025120 Rapid thermal cycling device  
A lid for a well plate is provided. Pins penetrate the lid and project downwardly into the wells of the well plate. Thermal energy is applied to the upper end of the pin to regulate the temperature...
6991766 Apparatus for automated synthesis  
Disclosed is an apparatus for automated synthesis containing a shaker deck with a plurality of reaction blocks containing a plurality of reaction wells, an arm containing an array of extending...
6962821 Thermal cycler including a temperature gradient block  
A method in which a temperature gradient is generated across a “gradient” block, and an apparatus comprising a block across which a temperature gradient can be generated. By setting up such a...
6905856 Soluble GlcNAc phosphotransferase  
The present invention relates to a soluble GlcNAc phosphotransferase, a method of making the same and a method of phosphorylating with the same.
6889468 Modular systems and methods for using sample processing devices  
Sample processing systems and methods of using those systems for processing sample materials located in devices that are separate from the system are disclosed. The sample processing systems...
6861242 Methods for producing highly phosphorylated lysosomal hydrolases  
The present invention provides highly phosphorylated lysosomal hydrolases, methods of modifying lysosomal hydrolases with the lysosomal targeting pathway enzymes GlcNAc-phosphotransferase and/or...
6828135 Phosphodiester α-GlcNAcase of the lysosomal targeting pathway  
The present invention provides nucleotide and amino sequences of the lysosomal targeting pathway enzyme phosphodiester α-GlcNAcase, methods of producing and methods of purifying this enzyme.
6800472 Expression of lysosomal hydrolase in cells expressing pro-N-acetylglucosamine-1-phosphodiester α-N-acetyl glucosimanidase  
The present invention provides methods of producing a pro-N-acetylglucosamine-1-phosphodiester α N-acetyl glucosimanidase (phosphodiester α-GlcNAcase), in mammalian cells deficient in the furin...
6787338 Method for rapid thermal cycling of biological samples  
A thermal cycling method and device is disclosed. The device comprises a sample chamber whose temperature can be rapidly and accurately modulated over a range of temperatures needed to carry out a...
6770468 Phosphodiester-α-GlcNAcase of the lysosomal targeting pathway  
The present invention provides nucleotide and amino sequences of the lysosomal targeting pathway enzyme phosphodiester α-GlcNAcase, methods of producing and methods of purifying this enzyme.
6767512 Temperature-regulating block with temperature-regulating devices  
The invention concerns a thermostated block for laboratory thermostats and comprising wells at a wells side to receive and make large-area contact with the parts of vials filled with sample liquids...
EP1137490B1 ROTARY THERMOCYCLING APPARATUS  
Abstract not available for EP1137490 Abstract of corresponding document: WO0033962 A rotary thermocycling apparatus, especially for biochemical reactions. The apparatus comprises a plurality of...
6719949 Apparatus and method for transporting sample well trays  
An apparatus for transporting sample well trays with respect to a heating device is provided. The apparatus includes a sample well tray holder, a rotational actuator, and a biasing mechanism. The...
6670165 Methods for producing highly phosphorylated lysosomal hydrolases  
The present invention provides highly phosphorylated lysosomal hydrolases, methods of modifying lysosomal hydrolases with the lysosomal targeting pathway enzymes GlcNAc-phosphotransferase and/or...
6640891 Rapid thermal cycling device  
A thermal cycling device consisting of a plate containing a plurality of wells to hold liquid and a lid that covers the plate and contains a number of “pins” that insert into the wells of the...
6569627 Monitoring hybridization during PCR using SYBR™ Green I  
The present invention is directed to a method and kits for monitoring a nucleic acid during amplification. More particularly, the present invention relates to a method wherein the nucleic acid is...
6537785 Methods of treating lysosomal storage diseases  
The present invention provides methods of treating lysosomal storage disease with highly phosphorylated lysosomal hyrdrolases.
6534300 Methods for producing highly phosphorylated lysosomal hydrolases  
The present invention provides highly phosphorylated lysosomal hydrolases, methods of modifying lysosomal hydrolases with the lysosomal targeting pathway enzymes GlcNAc-phosphotransferase and/or...
6448066 Rotary thermocycling apparatus  
A method for carrying out sequential reactions, e.g., sequential biochemical reactions, and a rotary thermocycling apparatus especially adapted for conducting such reactions, for example,...
6413780 Structure and method for performing a determination of an item of interest in a sample  
A method of performing a determination of an item of interest in a sample using a single structure is disclosed. A sample is provided accessible to the single structure. A first container for...
6323035 Systems and methods for handling and manipulating multi-well plates  
The invention provides exemplary systems, devices and methods for manipulating and handling multi-well plates. In one exemplary embodiment, a system is provided which comprises a robot having a...
6300142 Device and apparatus for conducting an assay  
A apparatus for assaying glycated proteins and other analytes in biological samples such as blood, in which a sample is presented to the apparatus, includes an inlet port between moveable between...
6245514 Fluorescent donor-acceptor pair with low spectral overlap  
The present invention relates to fluorescence resonance energy transfer pairs for detecting the presence of a target analyte wherein the donor fluorophore's emission spectrum and the acceptor...
6232079 PCR method for nucleic acid quantification utilizing second or third order rate constants  
The present invention is directed to a method of determining the concentration of a nucleic acid product that had been amplified through polymerase chain reaction (PCR). More particularly, the...
6174670 Monitoring amplification of DNA during PCR  
Methods of monitoring hybridization during polymerase chain reaction are disclosed. These methods are achieved with rapid thermal cycling and use of double stranded DNA dyes or specific...
6103193 Automatic immunoassay method and apparatus  
An automatic immunoassay method and apparatus which not only permit automatic operations of supplying and discarding reaction tubes, washing for B/F separation, dispensation of reagents, and...
6054263 Thermal cycler including a temperature gradient block  
A method in which a temperature gradient is generated across a "gradient" block, and an apparatus comprising a block across which a temperature gradient can be generated. By setting up such a...
6015534 PCR sample tube  
A one-piece sample tube for use in a PCR thermal cycler having a first substantially cylindrically shaped upper wall section having an external conically beveled shoulder moulded around the entire...
5935522 On-line DNA analysis system with rapid thermal cycling  
An apparatus particularly suited for subjecting biological samples to any necessary sample preparation tasks, subjecting the sample to rapid thermal cycling, and then subjecting the sample to...
5840573 Molecular analyzer and method of use  
A molecular analyzer and method of use for sensitive, rapid and accurate detection of specific, or target, molecules or specific parts of molecules in a liquid sample to be detected without the use...
5779981 Thermal cycler including a temperature gradient block  
A method in which a temperature gradient is generated across a "gradient" block, and an apparatus comprising a block across which a temperature gradient can be generated. By setting up such a...
5710381 Two piece holder for PCR sample tubes  
A two-piece plastic holder for loosely holding microliter sample tubes of a preselected design, each tube having a cylindrically shaped upper section open at its top end, a closed, tapered lower...
5656493 System for automated performance of the polymerase chain reaction  
There is disclosed herein a machine for performing nucleic acid amplification under computer control. The machine utilizes any one of a number of heating and cooling systems under control of a host...
5602756 Thermal cycler for automatic performance of the polymerase chain reaction with close temperature control  
An instrument for performing highly accurate PCR employing a sample block in microtiter tray format. The sample block has local balance and local symmetry. A three zone film heater controlled by a...
5576218 Method for thermal cycling nucleic acid assays  
The method for thermal cycling of nucleic acid assays includes a blended fluid stream produced from a plurality of constant velocity, constant volume, constant temperature fluid streams wherein to...
Matches 1 - 50 out of 58 1 2 >