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7427380 Automated system and method for simultaneously performing a plurality of signal-based assays  
An automated detection system includes a robotic fluid handling system for performing a plurality of assays; a detection system for imaging the assays as they are performed; and a computer control,...
7371517 High purity X-chromosome bearing and Y-chromosome bearing populations of spermatozoa  
Isolated non-naturally occurring populations of spermatozoa ( 15 ) having high purity and technologies to differentiate spermatozoa ( 28 ) based on characteristics such as mass, volume,...
7329496 Sequencing of surface immobilized polymers utilizing microflourescence detection  
Means for simultaneous parallel sequence analysis of a large number of biological polymer macromolecules. Apparatus and methods may use fluorescent labels in repetitive chemistry to determine...
7227633 Optical substrate for enhanced detectability of fluorescence  
A sample substrate adapted for use with fluorescence excitation light with a first wavelength. A reflector is disposed on a base. The reflector includes a reflecting multilayer interference coating...
7221453 Optical apparatus  
Various optical apparatus provide a source of parallel light ( 7, 75 ). The parallel light ( 7, 75 ) is generally achieved by directing an incident beam at the apex of a prism ( 1, 22, 24, 26, 28...
EP1783528A2 Fluorescence imaging system compatible with macro and micro scanning objectives  
The invention relates to an optical scanning method comprising generating and combining a first and a second beam to form an incident beam (119); directing said incident beam through an objective...
7208265 Method of cryopreserving selected sperm cells  
The present invention provides a method of cryopreserving sperm that have been selected for a specific characteristic. In a preferred embodiment, the method is employed to freeze sex-selected...
7195920 Collection systems for cytometer sorting of sperm  
Improved flow cytometer system particularly adapted to use for sex-selected sperm sorting include enhanced sheath fluid and other strategies which minimize stress on the sperm cells, including a...
7169548 Sperm cell processing and preservation systems  
Methods and apparatus are disclosed for processing sperm cells to accomplish preservation for future use while minimizing the adverse effects of such preservation. Sperm cells may be collected from...
7094527 System for in-vitro fertilization with spermatozoa separated into X-chromosome and Y-chromosome bearing populations  
An IVF system for successfully utilizing spermatozoa separated into X-chromosome bearing and into Y-chromosome bearing population for insemination. The IVF system includes fertilization medium that...
7024316 Transiently dynamic flow cytometer analysis system  
A flow cytometry apparatus and methods to process information incident to particles or cells entrained in a sheath fluid stream allowing assessment, differentiation, assignment, and separation of...
6992761 Broad range light detection system  
Broad-range light-detection systems, including components and methods of use thereof. These systems may include apparatus and methods for detecting light with increased speed and/or detection...
6982431 Sample analysis systems  
Systems, and components thereof, for analyzing samples. These systems include apparatus and methods for generating, transmitting, detecting, and/or analyzing light, including without limitation...
6975899 Multi-modal optical tissue diagnostic system  
An apparatus and method according to the invention combine more than one optical modality (spectroscopic method), including but not limited to fluorescence, absorption, reflectance, polarization...
6835946 Image reading method and apparatus  
An image reading apparatus is adapted for irradiating an image carrier including a labeling substance contained in two-dimensionally distributed spots with a stimulating ray and photoelectrically...
6825921 Multi-mode light detection system  
Apparatus and methods for combining multiple modes and methods of optical detection, postprocessing, and/or feedback loops in bioanalytical measurements. The methods may include (1) positioning a...
6800452 Automated methods for simultaneously performing a plurality of signal-based assays  
An automated detection system includes a robotic fluid handling system for performing a plurality of assays; a detection system for imaging the assays as they are performed; and a computer control,...
6746864 Automated system for simultaneously performing a plurality of signal-based assays  
An automated detection system includes a robotic fluid handling system for performing assays on the plurality of test samples; a detection system for imaging the assays as they are performed; and a...
EP0500717B2 TWO-PHOTON LASER SCANNING MICROSCOPY  
Abstract not available for EP0500717 Abstract of corresponding document: US5034613 A laser scanning microscope produces molecular excitation in a target material by simultaneous absorption of two...
RE38307 Method and apparatus for three-dimensional microscopy with enhanced resolution  
A method and apparatus for three dimensional optical microscopy is disclosed which employs dual opposing objective lenses about a sample and extended incoherent illumination to provide enhanced...
6576476 Chemiluminescence detection method and device  
A device for detecting chemiluminescence from a sample. The device may include a stage for supporting a sample and one or more of the following elements: (1) an optics head, (2) an optical relay...
6499366 Sample feeder  
Devices for automatically feeding sample containers into and out of an analyzer. The device may include (1) a first station that receives and initiates transport of a sample container into an...
6498335 Broad range light detection system  
A broad-range light-detection system. In some embodiments, the system includes apparatus and methods for detecting light with high accuracy over a broad range of intensities. In other embodiments,...
6483582 Apparatus and methods for time-resolved spectroscopic measurements  
Apparatus and methods for measuring light transmitted from a sample. The apparatus may include a stage, a light source, and a detector. The stage may be configured to hold a microplate having a...
6469311 Detection device for light transmitted from a sensed volume  
A high-throughput light detection instrument and method are described. In some embodiments, switch mechanisms and optical relay structures permit different light sources and/or detectors to be...
6466316 Apparatus and methods for spectroscopic measurements  
Apparatus and methods for measuring light transmitted from a sample. The apparatus may include a stage, a light source, and a detector. The stage may be configured to hold a microplate having a...
6402986 Compositions and methods for luminescence lifetime comparison  
This patent disclosure describes novel compositions and methods used in the verification of products or documents based on the reading of emitted light from luminescent compositions that can be...
EP0632887B1 FLUOROMETER DETECTION SYSTEM  
Abstract not available for EP0632887 Abstract of corresponding document: US5323008 An improved fluorescence detection system is provided which utilizes a relatively high powered, relatively high...
6344653 Multi-photon laser microscopy  
A laser scanning microscope produces molecular excitation in a target material by simultaneous absorption of three or more photons to thereby provide intrinsic three-dimensional resolution....
6326605 Broad range light detection system  
A broad-range light-detection system. In some embodiments, the system includes apparatus and methods for detecting light with high accuracy over a broad range of intensities. In other embodiments,...
6317207 Frequency-domain light detection device  
Apparatus and methods for determining temporal properties of photoluminescent samples using frequency-domain photoluminescence measurements, where the measurements may include photon counting...
6313960 Optical filter holder assembly  
Devices for using optical filters in a filter holder that enable optical filters to be simply, conveniently, and flexibly interchanged.
6297018 Methods and apparatus for detecting nucleic acid polymorphisms  
Methods and apparatus for detecting polynucleotide hybridization in luminescence-based assays. The methods may include (1) allele-specific hybridization, using luminescence detection, (2)...
6187267 Chemiluminescence detection device  
A device for detecting chemiluminescence from a sample. The device may include a stage for supporting a sample and one or more of the following elements: (1) an optics head, (2) an optical relay...
6177990 Optical substrate for enhanced detectability of fluorescence  
A sample substrate for use in a fluorescence imaging system includes a rigid base with a specularly reflective surface, typically metal, on which is deposited a transparent coating layer. The...
6166385 Multi-photon laser microscopy  
A laser scanning microscope produces molecular excitation in a target material by simultaneous absorption of three or more photons to thereby provide intrinsic three-dimensional resolution....
6159425 Sample transporter  
Devices and methods for supporting a sample container. In one embodiment, the device includes a holder for supporting a sample container, and a releasable clamp mechanism that applies a force...
6140048 System for distinguishing fluorescent molecule groups by time resolved fluorescence measurement  
System and method for distinguishing at least two types of molecule groups that are bound to analyte molecules and which have different fluorescent characteristics. The system performs...
6111258 Method for working in a specimen and a stage for the method  
A method for working in a specimen includes the steps of (a) putting the specimen on a stage; (b) irradiating radiation to the specimen for excitation; (c) recording detected characteristics of the...
6097025 Light detection device having an optical-path switching mechanism  
A high-throughput light detection instrument and method are described. In some embodiments, switch mechanisms and optical relay structures permit different light sources and/or detectors to be...
6071748 Light detection device  
A high-throughput light detection instrument and method are described. Confocal optics structure enables exclusive light detection from a sensed volume in a composition.
6060598 Fluorescence immunoassays using fluorescent dyes free of aggregation and serum binding  
Fluorescence immunoassays methods are provided which use fluorescent dyes which are free of aggregation and serum binding. Such immunoassay methods are thus, particularly useful for the assay of...
6055451 Apparatus and method for determining tissue characteristics  
An apparatus and method embodying the invention include utilizing a device intended to be inserted into a patient's body to determine a characteristic of a target tissue. In one apparatus and...
6033100 Floating head assembly  
Devices and methods for transmitting light through an aperture in a surface substantially without leakage. In one embodiment, the device comprises an optical relay structure having an end...
6025985 Moveable control unit for high-throughput analyzer  
A moveable control unit for a high-throughput analyzer that can be operatively mounted at a plurality of locations on the analyzer housing.
6008892 Optical substrate for enhanced detectability of fluorescence  
A sample substrate for use in a fluorescence imaging system includes a rigid base with a specularly reflective surface, typically metal, on which is deposited a transparent coating layer. The...
5955736 Reflector assembly for fluorescence detection system  
A sample card transport station moves a test sample card from an incubation station for the card to a transmittance and fluorescence optical station in a sample testing machine. The sample card...
5925884 Fluorescence station for biological sample testing machine  
A sample card transport station moves a test sample card from an incubation station for the card to a transmittance and fluorescence optical station in a sample testing machine. The sample card...
5888455 Optical reader and sample card transport stations for biological sample testing machine  
A sample card transport station moves a test sample card from an incubation station for the card to a transmittance and fluorescence optical station in a sample testing machine. The sample card...
5876672 Transient state luminescene assay apparatus  
Light, pulsed or continuous at a wavelength (e.g. 780 nm), fluoresceces a specimen. The specimens may be combinations of a dye (preferably labelled), an antigen (e.g. rubella) and an antibody...
Matches 1 - 50 out of 69 1 2 >