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7413753 Calcium phosphate delivery vehicles for osteoinductive proteins  
A composition for delivery of osteogenic proteins is disclosed. The composition comprises an osteogenic protein, a calcium phosphate material as a carrier, and an effective amount of an...
7390498 Method of forming bone with porous βtricalcium phosphate granules  
A porous β-tricalcium phosphate material for bone implantation is provided. The multiple pores in the porous TCP body are separate discrete voids and are not interconnected. The pore size diameter...
7381048 Stents with profiles for gripping a balloon catheter and molds for fabricating stents  
Embodiments of stents having profiles that improve gripping of the stent on a stent delivery system are provided. Additionally, embodiments of molds for fabricating the stents are provided.
7371410 Bone graft substitute composition  
A bone graft substitute composition can include essentially of calcium sulfate, a mixing solution, and a plasticizing substance. A bone graft substitute composition can include calcium sulfate,...
7371409 Bone graft substitute composition  
A bone graft substitute composition can include essentially of calcium sulfate, a mixing solution, and a plasticizing substance. A bone graft substitute composition can include calcium sulfate,...
7371408 Bone graft substitute composition  
A bone graft substitute composition comprising calcium sulfate; a mixing solution selected from the group consisting of sterile water, sodium chloride, phosphate buffered saline, potassium...
7365052 Tendon-inducing methods  
Compositions of proteins with tendon/ligament-like tissue inducing activity are disclosed. The compositions are useful in the treatment of tendinitis and tendon or ligament defects and in related...
7365051 Compounds with improved cartilage-inducing and/or bone-inducing activity  
The present invention concerns a bioactive implant material having a cartilage-inducing and/or bone-inducing activity composed of two components A and B, of which A is a bone-inducing and/or...
7357941 Method of delivering a bioactive agent with porous β-tricalcium phosphate granules  
A porous β-tricalcium phosphate material for bone implantation is provided. The multiple pores in the porous TCP body are separate discrete voids and are not interconnected. The pore size diameter...
7329366 Method of polishing implantable medical devices to lower thrombogenecity and increase mechanical stability  
The present invention relates to a method of polishing an implantable medical device. The method may include positioning an implantable medical device on a support. At least a portion of a surface...
7323445 Methods and compositions for healing and repair of articular cartilage  
Methods and compositions are provided for the treatment of articular cartilage defects and disease involving the combination of tissue, such as osteochondral grafts, with active growth factor. The...
7311734 Intervertebral spacers  
One embodiment of a hollow spinal spacer ( 10 ) includes a curved anterior wall ( 11 ) having opposite ends ( 12, 13 ), a posterior wall ( 15 ) having opposite ends ( 16, 17 ), two lateral walls (...
7309232 Methods for treating dental conditions using tissue scaffolds  
The invention provides methods, apparatus and kits for regenerating dental tissue in vivo that are useful for treating a variety of dental conditions, exemplified by treatment of caries. The...
7300772 BMP products  
Purified BMP-2 and BMP-4 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue...
7297758 Method for extending shelf-life of constructs of semi-crystallizable polymers  
This invention relates to a method of extending the shelf-life of constructs, in particular bioabsorbable stents, comprising semi-crystalline polymers by increasing the crystallinity of the polymers.
7297159 Selective coating of medical devices  
Methods for coating different regions of an implantable device are disclosed. An embodiment of the method includes dipping a first portion of the implantable device into a first coating substance,...
7291179 Bone graft substitute composition  
Bone graft substitute compositions and methods of making the compositions are disclosed. In some embodiments, a method of making a composition includes contacting a mixing solution with a first...
7291166 Polymeric stent patterns  
Patterns for polymeric radially expandable implantable medical devices such as stents for implantation into a bodily lumen are disclosed. Some patterns comprise radially expandable cylindrical...
7285304 Fluid treatment of a polymeric coating on an implantable medical device  
A method of manufacturing an implantable medical device including applying a composition to an implantable medical device, the composition including a polymer, an active agent and a solvent;...
7276081 Bone grafts  
A spinal spacer 300 for engagement between vertebrae is provided which includes a body 301 formed of a bone composition. The body 301 includes a first end 311 , an opposite second 315 end,...
7258891 Stent mounting assembly and a method of using the same to coat a stent  
A stent mounting device and a method of coating a stent using the device are provided.
7255698 Apparatus and method for anterior spinal stabilization  
A spinal fixation device for stabilizing one or more segments of the human spine and for preventing the dislodgement of intervertebral spinal fusion implants, which remains permanently fixated once...
7241874 Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue  
A method for purifying bone-derived osteogenic proteins including a demineralization process, a protein extraction process, a high molecular weight ultrafiltration process, a low molecular weight...
7238186 Interbody fusion device and method for restoration of normal spinal anatomy  
An interbody fusion device in one embodiment includes a tapered body defining a hollow interior for receiving bone graft or bone substitute material. The body defines exterior threads which are...
7229471 Compositions containing fast-leaching plasticizers for improved performance of medical devices  
Medical implants containing a temporary plasticizer, methods of producing such implants, and methods of using the implants in treating a disease, or ameliorating one or more symptoms thereof, in a...
7226587 Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins  
Compositions and methods for systemic administration of DNA encoding bone morphogenic proteins for promotion of osteogenesis are disclosed. The compositions and methods of the invention may be...
7217691 Methods of treatment of periodontal disease  
Purified BMP-2 and BMP-4 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue...
7211271 Method to improve hydroxyapatite implantation and stimulate bone regeneration  
Hydroxyapatite is treated by a combination of nitridation and the application of bone morphogenetic protein or DNA encoding such a protein to improve the tissue compatibility and affinity of the...
7211266 Bone graft substitute composition  
A composition includes calcium sulfate hemihydrate, stearic acid, an accelerant, and a mixing solution. The composition can be injected, e.g., through a needle, and is capable of setting, e.g., in...
7198675 Stent mandrel fixture and method for selectively coating surfaces of a stent  
A stent mandrel fixture for supporting a stent during the application of a coating substance is provided. A method supporting a stent during the application of a coating substance is also provided.
EP0934087B1 CERAMIC FUSION IMPLANTS AND COMPOSITIONS CONTAINING OSTEOINDUCTIVE FACTORS  
Abstract not available for EP0934087 Abstract of corresponding document: WO9817330 Bone graft substitute compositions are provided for promoting new bone growth and arthrodesis. The compositions...
7189392 Injectable carrier formulations of hyaluronic acid derivatives for delivery of osteogenic proteins  
An injectable formulation is disclosed for delivery of osteogenic proteins. The formulation comprises a pharmaceutically acceptable admixture of an osteogenic protein; and formulations comprising...
7147666 Monolithic implants with openings  
A monolithic bioresorbable implant includes optimally designed openings to treat tissue disorders or drug delivery. Preferably, the implant is made from calcium salts. A method of filling a...
7128927 Emulsions for in-situ delivery systems  
The invention is provides a composition for sustained delivery of a biologically active agent comprising a biologically active mixture and a controlled release formulation. The composition protects...
7091007 DNA molecules encoding BMP receptor proteins  
Novel serine/threonine receptor proteins and BMP receptor proteins are disclosed, as well as DNA molecules encoding the BMP receptor proteins and methods of using the receptor proteins. Further...
7087086 Biological agent-containing ceramic coating and method  
The invention provides an implantable article, a method of preparing the same, and methods of modifying a ceramic-coated implantable article. The implantable article comprises a biocompatible...
7077860 Method of reducing or eliminating thrombus formation  
An implantable stent is coated with a material that attracts heparin and with which heparin forms a bond. The stent is exposed to a heparin containing solution just prior to implantation or is...
7074221 Anterior cervical plate system  
Anatomically contoured anterior cervical plates with bone ingrowth surfaces, providing for intersegmental compressive preloading, and a rigid and locked interface to all of the bone screws, with...
6984623 Tendon-inducing compositions  
Compositions of proteins with tendon/ligament-like tissue inducing activity are disclosed. The compositions are useful in the treatment of tendinitis and tendon or ligament defects and in related...
6977095 Process for producing rigid reticulated articles  
A process for producing a rigid reticulated article involves coating a reticulated substrate which has open, interconnected porosity with a first dispersion comprising a ceramic or metal powder to...
6972019 Interbody spinal implant with trailing end adapted to receive bone screws  
A spinal fusion implant for insertion between adjacent vertebral bodies has opposed upper and lower surfaces adapted to contact each of the adjacent vertebral bodies from within the disc space, a...
6958223 Methods for producing extracellular matrix proteins  
Incorporation of certain amino acid analogs into polypeptides produced by cells which do not ordinarily provide polypeptides containing such amino acid analogs is accomplished by subjecting the...
6949251 Porous β-tricalcium phosphate granules for regeneration of bone tissue  
A porous β-tricalcium phosphate material for bone implantation is provided. The multiple pores in the porous TCP body are separate discrete voids and are not interconnected. The pore size diameter...
EP0836454B1 REINFORCED POROUS SPINAL IMPLANTS  
Abstract not available for EP0836454 Abstract of corresponding document: US5702449 One embodiment of a spinal implant 10 includes a body 11 sized and configured for engagement between adjacent...
6869445 Packable ceramic beads for bone repair  
Adherent packed beds of ceramic beads, each comprising a ceramic body coated with a biodegradable polymer, and fabric bags containing such beads in a packed, self-supporting configuration. The...
6858431 Bone mineralization proteins, DNA, vectors expression systems  
The present invention is directed to isolated nucleic acid molecules that encode LIM mineralization protein, or LMP. The invention further provides vectors comprising nucleotide sequences that...
EP0729325B1 OSTEOGENIC PRODUCT AND USE  
Abstract not available for EP0729325 Abstract of corresponding document: WO9513767 Disclosed is a product which includes calcium carbonate and bone growth factor useful for the promotion of bone...
6777001 Method of production of ceramics  
Spherical-shape ceramics obtained by dropping starting ceramics into a low temperature medium or composite spherical-shape ceramics having a composite layer obtained by applying a hydrothermal...
6774105 Methods of using latent TGF-β binding proteins  
Disclosed are novel nucleic acid and peptide compositions comprising latent TGFβ binding proteins (LTBPs). Also disclosed are methods of using LTBP-2 and LTBP-3 peptides and the DNA segments which...
6758849 Interbody spinal fusion implants  
The present invention discloses a spinal fusion implant that is at least partially cylindrical, made of material appropriate for human implantation and having preferably, but not necessarily, one...
Matches 1 - 50 out of 132 1 2 3 >