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7309789 |
4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof
Compounds are provided that, by way of their selective neurotransmitter binding useful for the treatment of various neurological and psychological disorders, e.g., ADHD. Such compounds are 4-phenyl...
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7265116 |
Aryl and heteroaryl substituted tetrahydroisoquinolines and use thereof
Provided herein are compounds of the formula (I):
wherein R 1 -R 8 are as described herein, R 4 being phthalazinyl, pyrazinyl, pyridazinyl, or quinoxalinyl. Such compounds are particularly...
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7220754 |
Mono-ester and asymmetrically substatuted di-ester pro-drugs of dopamide D1 receptor agonists
Mono-ester and asymmetrically substituted diesters of dihydrexidine, dinapsoline and A-86929 and substituted derivatives thereof are described. The novel ester/diester derivatives exhibit improved...
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7205425 |
Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for producing thereof
Optically active 1-substituted phenyl-2-nitro alcohol derivatives having the formula (1)
and the process for producing thereof, and 1-substituted phenyl-2-amino alcohol derivatives having the...
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7163949 |
4-phenyl substituted tetrahydroisoquinolines and use thereof
Provided herein are compounds of the formulae IA–IF. These compounds are tetrahydroisoquinolines of the following structure:
wherein R 1 –R 8 for compounds of each of the formulae IA, IB,...
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EP0947498B1 |
OPTICALLY ACTIVE NITRO ALCOHOL DERIVATIVES, OPTICALLY ACTIVE AMINO ALCOHOL DERIVATIVES, AND PROCESS FOR PREPARING THE SAME
Abstract of EP0947498 Optically active 1-substituted phenyl-2-nitro alcohol derivatives having the formula (1) <CHEM> and the process for producing thereof, and 1-substituted phenyl-2-amino...
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6632955 |
Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for preparing the same
Optically active 1-substituted phenyl-2-nitro alcohol derivatives having the formula (1) and the process for producing thereof, and 1-substituted phenyl-2-amino alcohol derivatives having the...
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EP0947498A1 |
OPTICALLY ACTIVE NITRO ALCOHOL DERIVATIVES, OPTICALLY ACTIVE AMINO ALCOHOL DERIVATIVES, AND PROCESS FOR PREPARING THE SAME
Optically active 1-substituted phenyl-2-nitro alcohol derivatives having the formula (1) and the process for producing thereof, and 1-substituted phenyl-2-amino alcohol derivatives having the...
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5668141 |
Trans-2,6-,3,6-and 4,6-diaza-5,6,6a,7,8,12b-hexahydrobenzo[c]phenanthrene compounds as dopamine agonists
A tetracyclic compound of the formula: ##STR1## wherein A and the atoms to which it is attached comprise a pyridine ring selected from: ##STR2## wherein R 1 , R 2 , and R 3 are specifically...
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5597832 |
Tetracyclic compounds as dopamine agonists
A tetracyclic compound of the formula: ##STR1## wherein A and the atoms to which it is attached and the optional double bond represent a mono- or di-heterocyclic ring selected from: ##STR2##...
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5378849 |
Substituted tetrahydroisoquinoline compounds, and process for producing them, and composition containing them
This invention provides certain novel substituted tetrahydroisoquinoline opticulisomers of the formula: ##STR1## wherein A represents the formula ##STR2## wherein R is hydrogen or halogen; R 1 is...
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5204468 |
Substituted 4,5,6,7-tetrahydrothiens[2,3-C]pyridine compounds
This invention provides the single species (-)-(S)-4-(3,4-dihydroxyphenyl)-7, 8-dihydroxy-1,2,3,4-tetrahydroisoquinoline hydrochloride hydrate, which is useful as a nephrovascular dilator.
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5079256 |
Substituted tetrahydroisoquinoline compounds and method containing them
A compound of the formula (I) or its salt and a process for producing the compounds. The compounds have the effect of dilating neophrovascular tracts; ##STR1## wherein ##STR2## represents the...
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4876261 |
Substituted tetrahydroisoquinoline compounds and composition containing them
A compound of the formula (I) or its salt and a process for producing the compounds; The compounds have the effect to dilate neophrovascular tracts; ##STR1## wherein ##STR2## represents the formula...
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4518779 |
1,2,3,4-Tetrahydro-1-aminomethyl-4-phenyl isoquinolines
1,2,3,4-Tetrahydro-1-aminomethyl-4-phenyl-isoquinolines useful as chemical intermediates and as pharmaceuticals and methods for their preparation.
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