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7361642 |
Canine specific growth hormone releasing hormone
A composition and a method of increasing growth hormone (“GH”) values in a canine or dog, and more specifically, a canine- or dog-specific growth hormone releasing hormone (“dGHRH”), or...
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7338656 |
Composition and method to alter lean body mass and bone properties in a subject
A method for decreasing the body fat proportion, increasing lean body mass, increasing bone density, or improving the rate of bone healing, or all, of a subject. Embodiments of the invention...
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7250405 |
Modified pituitary gland development in offspring from expectant mother animals treated with growth hormone releasing hormone therapy
The intramuscular electroporated injection of a protease-resistant growth hormone-releasing hormone (“GHRH”) cDNA into rat dams at 16 days of gestation resulted in the enhanced long-term growth...
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7250399 |
Compounds having growth hormone releasing activity
Compounds that promote growth hormone releasing activity are disclosed. These compounds have the formula:
A 1 -A 2 -X; A 1′ -X′; or A...
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7241744 |
Treating anemia in subjects by administration of plasmids encoding growth hormone releasing hormone
The present invention pertains to compositions and methods for plasmid-mediated supplementation. The compositions and method are useful for retarding the growth of the tumor, and retarding...
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7094869 |
Low molecular weight peptidomimetic growth hormone secretagogues
The present invention comprises growth hormone releasing peptides/peptidomimetics (GHRP) capable of causing release of growth hormone from the pituitary. Compositions containing the GHRP's of this...
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6716452 |
Active agent delivery systems and methods for protecting and administering active agents
A composition comprising a polypeptide and an active agent covalently attached to the polypeptide. Also provided is a method for delivery of an active agent to a patient comprising administering to...
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6468974 |
Compounds having growth hormone releasing activity
Compounds that promote growth hormone releasing activity are disclosed. These compounds have the formula: A 1 -A 2 -X; Al 1′ -X′; or A 1″ -Y These compounds can be present in a...
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6034216 |
Low molecular weight peptidomimetic growth hormone secretagogues
The present invention comprises growth hormone releasing peptides/peptidomimetics (GHRP) capable of causing release of growth hormone from the pituitary. Compositions containing the GHRP's of this...
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5972895 |
Composition and method for increasing growth hormone levels
A composition for promoting the release and elevation of growth hormone levels includes (1) an oligopeptide of the formula A1-D2methylTrp-Ala-Trp-DPhe-Lys wherein A1 is glutamine (Gln) or glutamic...
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5798337 |
Low molecular weight peptidomimetic growth hormone secretagogues
The present invention comprises growth hormone releasing peptides/peptidomimetics (GHRP) capable of causing release of growth hormone from the pituitary. Compositions containing the GHRP's of this...
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5795957 |
Polypeptide compounds containing D-2-alkyltryptophan capable of promoting the release of growth hormone
Novel peptides comprising D-2-alkyltryptophan, useful for promoting growth hormone release, compositions comprising such peptides and methods of using such compositions are described. In a...
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5776901 |
Polypeptide analogues having growth hormone releasing activity
Novel peptides of the formula A 1 -A 2 -C 1 -C 2 -C 3 -A 5 are disclosed which promote the release of growth hormone when administered to animals. These peptides can be used therapeutically.
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5663146 |
Polypeptide analogues having growth hormone releasing activity
Novel peptides of the formula A 1 -A 2 -Ala-Trp-DPhe-A 5 are disclosed which promote the release of growth hormone when administered to animals. These peptides can be used therapeutically.
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5534494 |
Polypeptide compounds having growth hormone releasing activity
Disclosed are novel polypeptide compounds which promote the release and elevation of growth hormone levels in the blood of animals. Also disclosed are methods of promoting the release and elevation...
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5120713 |
Treatment of obesity with an alpha-2-adrenergic agonist and a growth hormone releasing peptide
Obese patients may be effectively treated by cojointly administering an alpha-2-adrenergic agonist, such as clonidine, and a growth hormone releasing peptide, such as GHRH, to restore or...
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4880778 |
Combinations having synergistic growth hormone releasing activity and methods for use thereof
Disclosed are combinations of polypeptides acting in a synergistic manner to promote release and elevation of growth hormone levels in the blood of animals. Also disclosed are methods of promoting...
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4880777 |
Synthetic peptides having growth hormone releasing activity
Disclosed are novel polypeptides selected from the group consisting of: ##STR1## functional equivalents thereof: and organic and inorganic addition salts thereof; and ##STR2## functional...
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4839344 |
Polypeptide compounds having growth hormone releasing activity
Disclosed are novel polypeptide compounds which promote the release and elevation of growth hormone levels in the blood of animals. Also disclosed are methods of promoting the release and elevation...
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4501733 |
Polypeptides, a process for their preparation, their use, and a _process for the purification of polypeptides
Polypeptides of the formula I V--X--D--Trp--Y--D--Trp--Leu--Z--NH 2 wherein V represents a naturally occurring aminoacid or a physiologically acceptable acid radical, X represents a naturally...
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4455303 |
Renin inhibitors
A pentapeptide of the formula: H--A--B--C--D--E--OX wherein A, B, D are the same or different amino acid residues selected from the group consisting of Phe, Phe(4-Cl, Phe(4-F), Phe(4-Br),...
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4410513 |
Synthetic peptides having pituitary growth hormone releasing activity
Pentapeptides which act directly on the pituitary to release growth hormone therefrom.
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4410512 |
Combinations having synergistic pituitary growth hormone releasing activity
Novel combinations comprising (a) at least one peptide having the following amino acid sequence ##STR1## wherein X 1 , X 2 , and X 3 are selected from a group consisting of N-terminal and desamino...
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