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DE102018001512A1 Drug Primary Performance Monitoring Assay for the simultaneous determination of an analyte and an anti-analyte therapeutic  
The invention relates to a test for controlling primary drug effects (Drug Primary Performance Monitoring Assay), in which a simultaneous quantitative determination of an analyte and a directed...
DE102018000815A1 Method for the detection of biomarkers in the stool for the detection of diseases of the intestinal tract  
The invention teaches a method for detecting a tumor in the pancreas, wherein in a sample of human or animal stool one or more proteins selected from the group "PLRP1, PRSS2" optionally together...
DE102018009721A1 Method for diagnosing bornavirus infection  
The present invention relates to a method for the diagnosis of limbic encephalitis, PNS, encephalo-myelitis, leukoencephalopathy, retinitis or optic atrophy comprising the step of detecting a...
DE102017130322A1 Method and kit for the specific detection of diagnostically relevant proteins in biological samples  
The invention relates to a method for detecting at least one target protein in a sample containing proteins, comprising the steps: i. Sample preparation (eg homogenization, dilution etc. of the...
DE102017010842A1 A method of quantifying protein aggregates of a protein misfolding disease in a sample  
The invention relates to a method for quantifying protein aggregates of a protein misfolding disease in a complex sample. A device, a kit and a use of the device and the kit are disclosed.
DE112017002105T5 Method for the determination of DPP3 and therapeutic methods  
The present invention relates to methods for the determination of active DPP3 in a body fluid sample, an assay or kit for the determination of active DPP3 in a body fluid sample, a method for...
DE102017008885A1 Mass spectrometric method and MALDI-TOF mass spectrometer  
There are a number of standard methods for normalizing MALDI-TOF data, but these can not adequately compensate for the observed technical variability. The invention provides an improved...
DE102010006450B4 Stepped search for microbial spectra in reference libraries  
Method for identifying a microbial sample by calculating measures of similarity between the mass spectrum of the microbial sample and reference spectra of an entire library; comprising the steps...
DE212017000174U1 Protein chip for testing abnormally decarboxylated prothrombin in serum and kit  
A high-throughput protein chip for testing abnormally decarboxylated prothrombin in serum, characterized in that a plurality of test sub-regions are disposed on the substrate carrier of the...
DE102017215873A1 Method and device for determining a thermal damage degree of hair  
In various embodiments, a method for determining a thermal damage degree of hair is provided. The method may include: while exposing a hair sample of the hair to UV or UV / VIS light, capturing a...
DE102017110476B4 Preparation of biological cells on mass spectrometric slides for desorbing ionization  
Process for the preparation of proteins from samples of unpurified biological cells on a sample carrier for the mass-spectrometric determination of cell properties, comprising the steps: Providing...
DE102017116204A1 Method of predicting the response to cardiovascular regeneration  
The present invention relates to a method for predicting the response to cardiovascular regeneration, which comprises the use of biomarkers. Furthermore, the present invention relates to a...
DE102017115215A1 EF-TU BINDING METAL-BASED ANTIBIOTIC  
The invention relates to an N-heterocyclic carbene (NHC) Re (I) complex with an unsubstituted or substituted benzimidazol-2-ylidene ligand and their use, in particular in a pharmaceutical...
DE112011102286B4 Mass spectrometric quantification of analytes using a universal reporter  
A method for mass spectrometric (MS) quantification of an analyte, comprising Processing a heavy, isotopically-labeled sequence or portion thereof which, upon MS dissociation, fragments into a...
DE102017110476A1 Preparation of biological cells on mass spectrometric slides for desorbing ionization  
The invention relates to the preparation of biological cells for mass spectrometric analysis with respect to cell properties such as taxonomic classification, antibiotic resistance, drug behavior...
DE102017003571A1 Verfahren zum Nachweis sekundärer Botenstoffe mit fluoreszenzbasierten Sensorproteinen und Vorrichtung zur Durchführung des Verfahrens  
Die Erfindung betrifft ein Verfahren zum Nachweis sekundärer Botenstoffe gekennzeichnet durch die Schritte:- Zugabe eines fluoreszenzbasierten Sensorproteins in ein Behältnis,- Messung der...
DE102017107661A1 SH2B adapter protein-3 for the prediction of a bone marrow response and immune response  
The present invention relates to the SH2B adapter protein-3 (SH2B3) for use as a diagnostic marker. Furthermore, the present invention relates to a method for determining the expression of the...
DE102017002523A1 Method for the chromatographic quantitative determination of the amino acids valine, methionine, allo-isoleucine, isoleucine, leucine, tyrosine and phenylalanine in blood plasma  
In particular, a method for the chromatographic quantitative determination of the amino acids valine, methionine, allo-isoleucine, isoleucine, leucine, tyrosine and phenylalanine in blood plasma...
DE102017104774A1 Process for the enrichment of N-terminal peptides  
Process for the enrichment of N-terminal peptides from proteins of a sample, which comprises the following process steps: the extraction of the proteins from the sample, the chemical blocking of...
DE102004027429B4 Method for the use of marker value based density maps in the diagnosis of patients with diseases, in particular of tumors  
Method for the patient-specific assignment of a risk of being ill, based on n indicator substances from body fluids, characterized in that a) n> 1, b) measured values ​​of n indicator substances...
DE112016006111T5 Biochip und Verfahren zum Herstellen von diesem  
Es werden ein Biochip, der in der Lage ist, multivalente Bindungen zwischen Zielprotein und Bindungsmediator von monovalenten Bindungen zu detektieren und zu analysieren, und ein Verfahren zum...
DE112016004413T5 PROCESS FOR CLEANING PURE THIOFLAVIN T, METHOD FOR PRODUCING PURE THIOFLAVIN T, COMPOSITION CONTAINING THIOFLAVIN T, AND AMYLOID PROOF PROCESS  
The present invention relates to a method for purifying pure thioflavin T, which comprises a step of preparing a thioflavine T solution in which crude thioflavine T is dissolved in a polar...
DE102016124171A1 Serological test for therapy control of HPV16 positive carcinomas  
The present invention relates to a method for therapy control of HPV16 positive carcinomas, an antibody for use in a corresponding diagnostic method and a test for carrying out the method. The...
DE102012011648B4 Microbial microbial analysis by MALDI mass spectrometry  
A method for the mass spectrometric analysis of microbes from colonies on a nutrient surface in a mass spectrometer, comprising the steps of: (a) microbes are disrupted on the nutrient surface,...
DE102006009083B4 Mass spectrometric determination of the activity of blood enzymes  
Method for the determination of enzyme activities in blood, comprising the following steps: (a) providing whole blood, plasma or serum with active enzymes, (b) adding fixed amounts of one or more...
DE102017219909A1 Proteogenomic analysis system and method  
Methods for isolating nucleic acid and protein molecules from a single formalin-fixed paraffin-embedded (FFPE) tissue sample section include lysing the cells of the tissue sample section,...
DE102017218368A1 DEVICES, SYSTEMS AND METHODS FOR LIGHTING AND PICTURING OBJECTS  
An illumination system includes: a surface configured to have an imaging target disposed thereon; a light source, a beam splitter and at least a first mirror. The beam splitter is configured to...
DE102017012178A1 Devices, systems and methods for illuminating and imaging objects  
An illumination system includes: a surface configured to have an imaging target disposed thereon; a light source, a beam splitter and at least a first mirror. The beam splitter is configured to...
DE102015110182B4 Interchangeable module, analyzer, system and method for near-patient detection of compounds in a blood sample  
Interchangeable module (3) for use in an analyzer (5) for near-patient detection of compounds in a blood sample, wherein the interchangeable module (3) is designed to analyze a single blood sample...
DE102016217182A1 In vitro method for the identification and analysis of ion channels and / or water channels and / or receptors of signal transduction using a three-dimensional cell culture model of the sweat gland  
The present invention relates to an in-vitro method for the identification and analysis of ion channels and / or water channels and / or receptors of signal transduction in which first at least...
DE212017000022U1 An immunoinfiltration device for detecting fucosylated glycoprotein in serum  
An immunoinfiltration device for detecting fucosylated glycoproteins in serum, which comprises a microfiltration membrane (2), characterized in that the substrate of the microfiltration membrane...
DE112015005577T5 Method for determining the structure of a macromolecular aggregate  
A method of determining the structure of a macromolecular aggregate (MMA) comprises the steps of (a) generating precursor ions of an MMA species to be assayed; (b) transporting the MMA precursor...
DE102016010004B3 Identification of unknown transformation products without reference standard by comparing the mass spectra with predicted mass shifts by MS / MS  
The present invention relates to a method for the identification of unknown transformation products of a starting substance without reference standard by means of tandem mass spectrometry (MS /...
DE102009032649B4 Mass spectrometric identification of microbes by subspecies  
Method for the mass spectrometric identification of microbes comprising the steps of: (a) providing a library of reference spectra, (b) recording a mass spectrum of the microbial sample, (c)...
DE102007063902B3 Aptamers that bind to a target molecule involved in hemostasis  
Aptamer that binds to a target molecule involved in hemostasis, wherein the aptamer is an aptamer that binds to activated protein C, the aptamer having a dissociation constant KD in the range of ≥...
DE102016010887B3 A method for the qualitative detection of added protein materials in food  
According to the invention a method for the qualitative detection of added blood plasma in foods in meat and meat products is disclosed, wherein the foods are separated at the sample-treatment in...
DE202017105086U1 Fluorescence protein microarray and kit for detecting alpha-fetoprotein (AFP) in serum  
Fluorescence protein microarray for detecting AFP, characterized in that: the substrate glass slide of the fluorescence protein microarray comprises at least one detection section and the...
DE112006003967B4 Dyes, dye compositions and methods for staining proteins  
Compound which is selected from the group consisting of V07-03035, V07-03037, V07-05146, V07-05176, V07-05170, V02-06006, V07-05143, V07-03034, and combinations thereof, wherein the compounds are...
DE102016005169B3 Method for the identification of inhibitors of the primary nucleation of amyloid-beta aggregation  
The invention relates to a method for the identification of inhibitors of the primary nucleation of amyloid-beta aggregation, comprising the following steps: a) A-beta species is introduced into...
DE102015115158B4 Method and kit for the diagnosis of epithelial-mesenchymal transition (EMT) of the peritoneum  
A kit for the diagnosis of epithelial-mesenchymal transition (EMT) comprising agents for the detection of markers in a sample, the markers comprising a) an extracellular matrix protein, b) a...
DE112015004553T5 Column array structure with uniform nanometer interspaces with a high aspect ratio  
There is provided a technique for sorting entities. An inlet is configured to receive a fluid, and an outlet is configured to exit the fluid. An array of nano columns connected to the inlet and...
DE102015115640B4 Method for the detection of ligands by means of biosensors  
A method for detecting ligands (10) by means of biosensors (6) based on the riser resonance energy transfer principle, wherein a biosensor (6) is a protein comprising three sections, the first...
DE102015121187A1 Kit for a multiplexed drug discovery system with high-throughput properties  
The modular system comprises a container and a reporter group, which is connected to the container, preferably via a first linker (for example, L1), the reporter group preferably being configured...
DE102011005235B4 A method for identifying a subset of polynucleotides from a human polynucleotide starting dose for in vitro determination of a severity of the host response of a patient  
A method for identifying a subset of polynucleotides from a starting amount of polynucleotides corresponding to the human genome for in vitro determination of a severity of host response (host...
DE112015001580T5 Rapid method for analyzing blood samples for the identification of hemoglobin variants by electron transfer dissociation  
There is disclosed a method for screening or testing a sample comprising ionizing a native human hemoglobin sample to produce parent or precursor ions, applying electron transfer dissociation...
DE112015003229T5 Method for assessing vaginal atrophy  
An array of methods for assessing vaginal atrophy is disclosed. The methods may be used per se or in combination with a treatment or as part of a kit.
DE112015003233T5 Method for assessing vaginal atrophy  
An array of methods for assessing vaginal atrophy is disclosed. The methods may be used per se or in combination with a treatment or as part of a kit.
DE102015219047B3 Method for quantitative determination of saccharin in the liquid phase by means of an indicator dye  
The present invention relates to a photometric analysis method for the quantitative determination of saccharin in a solution. In the method, the extinction of a saccharin-protonable indicator dye...
DE102005029845B4 Verfahren zur Diagnose von rheumatischen Erkrankungen  
Polypeptid abgeleitet von nativem Vimentin mit der SEQ ID No. 1, dadurch gekennzeichnet, dass es gegenüber der nativen Sequenz in mindestens einer der Positionen 16, 17, 19, 41, 58, 59, 60, 68,...
DE102015115640A1 Method for the detection of ligands by means of biosensors  
A method for detecting ligands 10 by means of biosensors 6 based on the riser resonance energy transfer principle, wherein a biosensor 6 is a protein comprising three sections, the first section...