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DE4433261B4 New methods for the functional characterization of ion channels and functional identification of modulators of such membrane proteins  
process for the functional characterization of ion channels and / or associated therewith Receptors, characterized in that an in vitro cell system to perform a flux assays with non-radioactive,...
DE10227042B4 A method for detecting, quantifying and / or characterizing an analyte  
process for detecting, quantifying and / or characterizing a in a first liquid Analyte contained (10) comprising the steps of: a) contacting and incubating the analyte (10) each having an affinity...
DE10339996A1 Analysis of different reagents, e.g. for the amplification of DNA sequences, has reagents bonded to spots on a chip each to be covered by a sample droplet for reactions to be analyzed by PCR  
The analysis technique for reagents prepares a chip (1) surface with at least two spots (2), where two different reagents of a first set are bonded unspecifically. A sample solution containing a...
DE10339597A1 Apparatus and methods for detecting biochemical activity comprising gap junctions  
It is an apparatus and a method for the detection of biochemical activity described with a detection reaction, wherein the detected biochemical activity spatial separated extends from the...
DE10136008B4 A process for the analysis of macromolecules and methods for producing an analytical device  
process for the analysis of macromolecules with the aid of a microarray, which of a plurality of spots (16) in a known Arrangement is that comprise a plurality of first macromolecules, the for a...
DE10321809A1 A method of printing biomolecules  
The The present invention relates generally to the field of biotechnology. In particular, the invention relates to a method for the controlled Uptake and release of biomolecules in solid,...
DE10337668A1 Molecular probe and material for detecting an analyte, and their use  
The Invention relates to a molecular probe (MS) for the detection of a Analyte (AN), comprising a base structure (GS); at least two directly or indirectly to the base structure (GS) bound detector...
DE10336760A1 Method for in vivo labeling of defined cell types in a tissue, useful for detecting specific cells and to establish expression profiles, by providing cell-specific expression of fluorescent protein  
Method for in vivo labeling of a defined cell type within a tissue by cell-specific expression of at least one nucleic acid (I) that expresses a subcellularly localized autofluorescent protein...
DE102004036765A1 Masking chemical arrays  
It is a method of using a chemical array unit discloses that a chemical array with probes at multiple feature locations having. A request to enable an assay can be read, wherein the test part of...
DE202004014858U1 Apparatus for mass spectrometry  
device for identifying a modified protein with: agents for digestion and digestion of a modified protein for Preparation of a number of peptides; Means for ionizing at least one of the number of...
DE10331108A1 Test system for sterile analysis of biological fluids comprises beaker with lid which can form hermetic seal, test strip being either mounted inside beaker or outside it, when aperture connects it with interior of beaker  
Test system for sterile analysis of biological fluids comprises a beaker (1) with a lid (2) which can form a hermetic seal. A test strip (3) is either mounted inside the beaker or outside it, when...
DE102004027865A1 Manufacture of conductive carbon nanotubes dotted with metals for biosensors, involves combining carboxyl group of nanotube with amino group of substance having amino and thiol groups, and combining metal with thiol group  
The carboxyl group of a carbon nanotube (CNT) is combined with an amino group of a chemical substance having amino and thiol groups, to obtain CNT modified by thiol group. A metal is then combined...
DE10006760B4 Producing a protein biosensor with a defined bonding matrix  
Binding matrix, comprising a support having a first functionalized surface and to the support immobilized modified proteins, the first functional Groups binding complementary, not occur in the...
DE10318139B4 Selbstkonfigurerbarer biochip  
Of the biochip for the analysis of nucleic acid samples consists of a carrier with top, bottom and support body. at its top are reaction spaces for the synthesis or fixing Probe oligonucleotides...
DE20317723U1 Apparatus for carrying out a polymerase chain reaction or reverse transcriptase polymerase chain reaction, comprises that it measures electrical conductivity simultaneously  
An instrument measures electrical conductivity simultaneously with a polymerase chain reaction (PCR) or reverse transcriptase polymerase chain reaction (RT-PCR). An instrument measures electrical...
DE10333972A1 Sensor, for selective detection of biochemical molecules, comprises a cantilever of the layers formed by gas phase etching to shape a hollow at the under side of the substrate  
To produce a sensor (1), for biochemical measurements, an oxide layer (3) is formed on a substrate (2) and an active semiconductor layer is laid on it. At least one piezo resistance (4) is formed...
DE10333406A1 T-regulatory cells containing galectins for the therapy and diagnosis of diseases  
The This invention relates to T-regulatory cells containing Galectins for the therapy and diagnosis of diseases, in particular allergies, autoimmune diseases, chronic inflammation,...
DE10331093A1 Apparatus and method for direct quantitative in vitro determination of a substance contained in a sample  
The This invention relates to an apparatus and a method for direct quantitative in vitro determination of a in a sample Substance contained. The device according to the invention comprises on a...
DE10330981A1 Apparatus and method for the simultaneous performance of blood group determinations, serum cross-checking and antibody detection test  
The Invention relates to a device for the simultaneous, qualitative or quantitative determination of multiple analytes in a liquid sample, comprising a membrane 2 with- An application zone 5 for...
DE10330717A1 Device and method for the detection of analyte  
The Invention relates to an apparatus and a method for detecting of analyte.The object of the invention, an apparatus and to provide methods for the detection of analyte, the disadvantages of the...
DE10253664B4 diagnostic procedures  
Diagnostic procedures, in particular for the determination of abusive manipulation of to be diagnosed body exudates at least one not by the subject, wherein the subject or only slightly...
DE10230838B4 Diagnostic use of pharmaceutical substances  
use of pharmaceutical substances chlorpromazine quinacrine ethacridine lactate lovastatin doxorubicin D-penicillamine in a method of diagnosing chronic forms of neurodegenerative Diseases of the...
DE10330983A1 Device for lateral flow tests  
device for the simultaneous, qualitative or quantitative determination of several Analyte in a liquid Sample comprising a membrane 2 with- An application zone 5 to Applying the liquid Sample,- At...
DE10328394A1 Procedures for digestion and derivatization of biological samples and methods for bacterial detection  
The This invention relates to a method for the digestion and for derivatization of biological samples as well as a method of Detection of bacteria in these samples. In particular, the Invention...
DE10328624A1 A hybridizing process, for the study of biological material, the spots of an array on a microscope slide are in contact with a hybridizing solution in a set height level for the reaction time  
A hybridizing process, for the study of biological material, a substrate e.g. a microscope slide (1) is provided with spots (9) over the surface area as an array (3) using catch molecules. A...
DE19957065B4 Screening procedures for drugs  
process for screening drugs by testing whether a drug the interaction between macrophage migration inhibitory factor (MIF) and to the activation domain interrupts of c-Jun binding protein Jab,...
DE10326758A1 Substrate for controlled binding reactions, useful for (high throughput) nucleic acid hybridization assays, comprises carrier having a depression in which there are many test sites, separated by embankments  
A substrate (A) for controlled performance of specific (nucleic acid hybridization) binding reactions, is new. A substrate (A) for controlled performance of specific (nucleic acid hybridization)...
DE10326331A1 Inspection of microarrays and monitoring e.g. hybridization of macromolecules on them, prepares spot patterns on surfaces to sandwich fluid containing macromolecules  
The microarray is prepared with macromolecules on a solid surface (3) in a spot (5) pattern. A second pattern (7) is applied to a second surface (11). The surfaces are contacted by a fluid (13)...
DE10325152A1 Determining an unknown quantity of target molecule species, comprises contacting the target molecules with a defined quantity of reporter group-free aptamer molecules  
Determining an unknown quantity of target molecules comprising contacting the target molecules with a defined quantity of reporter group-free aptamer molecules, is new. The aptamer molecules form...
DE10324912A1 Method for detecting DNA point mutations (SNP analysis), and associated assembly  
at SNP analysis is utilized, a DNA hybridization and DNA chip used. Specifically, in a defined temporal Drain a liquid to be analyzed DNA sample via the DNA chip conducted. After hybridization...
DE102004003595A1 Substrate for the immobilization of physiological material and process for its preparation  
disclosed is a substrate for construction the immobilization of a physiological material comprising a substrate, a layer formed on the substrate, organic polymeric bonding material layer and a...
DE10323685A1 A method for the covalent immobilization of probe biomolecules to organic surfaces  
The Invention relates to a method for the covalent immobilization of probe biomolecules organic surfaces using photoreactive cross-linkers with which the probe biomolecules on a organic surface...
DE10323096A1 A method for inspecting an active influence on biological cells  
at a method for studying the drug influence on cells these are on a sample carrier (13, 14) are immobilized, the accommodated in a reaction chamber (12) is. By applying the reaction chamber with...
DE10314413A1 A method for detecting the expression of recombinant proteins on a cell surface and for immobilization and purification of proteins and cells  
The A method for detecting the expression of a recombinant polypeptide in / at / on the cell surface its host cell is characterized in that (a) the recombinant Polypeptide constructed such that in...
DE10320339A1 Preparing a carrier for detection of analytes, useful e.g. as DNA chip for protein expression studies, by synthesis of receptors on a surface, with introduction of hapten groups to allow monitoring the quality of synthesis  
Method for preparing a carrier (A) for detection of analytes (An) comprises supplying liquid, containing building blocks for synthesis of polymeric receptors (R) on a carrier; location and/or...
DE10319155A1 Electrically readable bonds of analyte molecules to probe molecules immobilized  
The Invention relates to the detection of the binding of analyte molecules, for example, biopolymer, to immobilized scavenger molecules.The Invention is the semiconductor plates (chips) of...
DE10317400A1 EX VIVO skin organ model from pigskin  
The Invention provides a method for producing an ex vivo skin model Organ prepared from pig skin that particular is suitable for the examination of wound healing processes. In which Procedures...
DE10261650A1 Using the multifunctional transcription factor Yin Yang 1 and variants thereof for treating diseases, particularly type 1 diabetes  
The This invention relates to the influencing the activity and / or the expression of the multifunctional transcription factor Yin Yang 1 (YY1) and variants thereof for the treatment of various...
DE10318139A1 Selbstkonfigurerbarer biochip  
Of the biochip for the analysis of nucleic acid samples consists of a carrier with top, bottom and support body. At its top are reaction spaces for the synthesis or fixing Probe oligonucleotides...
DE10317402A1 Ex vivo skin organ model, especially for male skin  
The Invention provides a method for producing an ex vivo skin model Organ for male Skin ready. The process comprises the removal of skin dermis and epidermis of the body or Body part of a Pig and...
DE19802576B4 Process for the simultaneous identification of proteins and their binding partners  
process for the simultaneous identification of proteins and their binding partners, in which a) proteins or protein aggregates from a biological source isolated and separates, b) the separated...
DE10316689A1 Three-dimensional chip  
chip for studying biological material with a carrier unit porous Material to which serves the detection of sample molecules reference molecules are immobilized.
DE10313324A1 Preparing sorbent having at least two groups for selective binding, useful, e.g. for detecting receptor-agent interaction, in drug screening and in substrate separation or purification  
Preparing a sorbent (A) with at least two different groups for selective binding of a substrate, is new. Preparing a sorbent (A) with at least two different groups for selective binding of a...
DE10309349A1 Apparatus for the analysis of an analyte such as a foodstuff, feces, water or fermenter sample, comprises a semiconductor chip carrier with immobilized receptors specific for particular ligands, and a pH sensor  
An analytical apparatus comprising a semiconductor chip with receptors for specific ligands which may be present in the sample, and further comprising at least one pH sensor, is new. An apparatus...
DE10314746A1 Biochip production, to be used in the study of nucleic acids and proteins, scatters the reference molecules at random over the carrier surface to bond with micro-particles, and a magnetic field arranges them in set positions.  
Producing a biochip, with a carrier where reference molecules are bonded to micro-particles, comprising spreading the reference molecules at random over the surface and documenting their...
DE10313515A1 Biochip for pixel-oriented photometric detection of biomolecules, comprises a transparent plastic surface with spots that are functionalized so that the biochip can be used in an assay  
A biochip for pixel-oriented photometric detection of biomolecules comprises a transparent plastic surface with 2-8 mm2> spots that are functionalized so that the biochip can be used in an assay...
DE10313098A1 Test system for finding active ingredients against prion induced diseases and drugs for the prevention and treatment of this disease  
The Invention relates to a test system for the discovery of active substances, which the inhibition of axon growth by infectious prions cancel, with the following components: a) a culture held in...
DE202004012163U1 System for hybridizing immobilized nucleic acid samples, in sealed hybridizing chambers, has a pressure assembly to build up the chamber pressures over ambient atmospheric levels to prevent the formation of air bubbles  
A system (1) with hybridizing chambers (5), to hybridize immobilized specimens on carriers (27), having chambers which are defined by the gap between the carrier and a cover (26), and which can be...
DE10312846A1 Test system for identifying substances FLOW The neurite outgrowth  
The invention relates to a method for the search or testing of active substances which affect the growth and survival of nerve cells, wherein a cell is contacted with at least one substance and...
DE10304775B3 Meter for a biosensor in smart card form and methods of measurement  
The invention relates to a measuring instrument and a measuring method for chip cards shaped biosensors (1) and method for producing the same. For this purpose, the biosensor (1) on a...