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DE112017004738T5 Determination of molecular structures and molecular arrangement structures from momentum transfer cross-section distributions  
Systems and methods are provided for de novo determinations of molecular structures or molecular arrangements, including biologically relevant protein structures or assemblies, exclusively from...
DE10262193B4 Cosmetic use of an active substance for stimulating type 2 and / or type 3 human beta-defensins, use of such an active substance for the preparation of a pharmaceutical composition containing such an active substance and use of such an active substance in the field of tissue reconstruction  
Cosmetic use of an active ingredient selected from the group consisting of a Boldo extract, a cocoa extract and jasmonic acid, wherein the extract is obtained by aqueous extraction or extraction...
DE102017130322A1 Method and kit for the specific detection of diagnostically relevant proteins in biological samples  
The invention relates to a method for detecting at least one target protein in a sample containing proteins, comprising the steps: i. Sample preparation (eg homogenization, dilution etc. of the...
DE102017220531A1 Adapter for a microfluidic device for transferring a substance, in particular a sample  
The invention relates to an adapter (100) for a microfluidic device (200), wherein the adapter (100) has a substance input chamber (111, 112, 113) and a connection channel (151, 152) fluidly...
DE102017010842A1 A method of quantifying protein aggregates of a protein misfolding disease in a sample  
The invention relates to a method for quantifying protein aggregates of a protein misfolding disease in a complex sample. A device, a kit and a use of the device and the kit are disclosed.
DE102018001796B4 GENES IN SANDERIA MALAYENSIS RESPONDING TO RISING SEAWATER TEMPERATURES, AND METHOD FOR PREDICTING PHYSICAL OR METABOLIC CHANGES OF SANDERIA MALAYENSIS  
A microarray chip for the detection of a strong stress stress strain of Sanderia malayensis on which oligonucleotides which form any nucleic acid sequence of those genes represented by SEQ. ID....
DE102016108115B4 Sample buffer with low molecular weight dye stabilizer for gel electrophoresis  
A sample buffer (100) for loading with a fluidic sample (106) to be separated, the sample buffer (100) comprising: a fluorescent dye (102) for coupling to the fluidic sample (106); a dye...
DE102017125335A1 Amplicon region as an epigenetic marker for the identification of immune cells, especially non-classical monocytes  
The present invention relates to a method, in particular an in vitro method for identifying non-classical monocytes, comprising analyzing the methylation status of at least one CpG position in the...
DE102017125150A1 Endosialin (CD248) as an epigenetic marker for the identification of immune cells, in particular naïver CD8 + T cells  
The present invention relates to a method, in particular an in vitro method, for identifying specific immune cells, in particular naive CD8 + T cells, comprising analyzing the methylation status...
DE102017218849A1 Reaction carrier for a microfluidic device and method for determining a nucleotide sequence  
The invention relates to a reaction support (100) for a microfluidic device (200) for determining a nucleotide sequence, comprising at least a first recess (101) and a second recess (102), wherein...
DE102017125019A1 PDCD1 as an epigenetic marker for the identification of immune cells, in particular PD1 + cells  
The present invention relates to a method, in particular an in vitro method, for identifying PD1 + cells comprising the analysis of epigenetic modifications / properties (including methylation...
DE102017214449B4 Method and means for the diagnosis of tumors by detection and quantification of heterogeneously methylated epialleles  
The invention relates to methods and means for the diagnosis of tumors, in particular for the early diagnosis and for the differentiation of benign and malignant tumors by means of digital PCR, in...
DE102017214449A1 Method and means for the diagnosis of tumors by detection and quantification of heterogeneously methylated epialleles  
The invention relates to methods and means for the diagnosis of tumors, in particular for the early diagnosis and for the differentiation of benign and malignant tumors by means of digital PCR, in...
DE112016006855T5 Method and apparatus for analyzing biomolecules  
The purpose of the invention is to provide a method for analyzing biomolecules, with which it is possible to suppress the clogging of nanopores with ease. The first embodiment of the invention is...
DE102017007521A1 DNA Security Concept and a biological-chenisches pocket laboratory - as a basis for modern security systems and the forensic analysis of the smallest traces  
A completely new individual and absolutely forgery-proof security concept is presented, based on the unique DNA of the individual. The human DNA (Deoxyribonucleicacid) can be described on any...
DE102018001796A1 GENESIS IN SANDERIA MALAYENSIS RESPONSING TO RISING TEMPERATURE OF SEAWATER, AND METHOD FOR PREDICTING PHYSIOLOGICAL OR METABOLOGICAL CHANGE OF SANDERIA MALAYENSIS  
The present invention relates to a Sanderia malayensis gene which responds to rising seawater temperature and to a method of predicting physiological or metabolic changes of Sanderia malayensis...
DE102017007181A1 A method of producing and forgery-proofing a medical device by using a nucleic acid of known partial sequence  
The invention relates to a method for the production and forgery-proof authentication of medical devices by using a nucleic acid having a known partial sequence, the method having the following...
DE112017002258T5 Biomolecule-measuring device  
An object of the present invention is to provide a biomolecule measuring device which can reduce the influence of an interaction between chambers. A biomolecule measuring device according to the...
DE102017114349A1 Detection system and method for its production  
A method of making a biomolecule detection system (114) in a medium (50) is disclosed. The method comprises: providing (S110) a first detector section (210) having a first channel region (215) and...
DE102017011226B3 Automated, integrated microfluidic system for high-throughput cloning  
The present invention relates to a stacked microfluidic system for the automated cloning of DNA, and to a method for cloning DNA in the stacked microfluidic system.
DE102017119427A1 Determining the age of a human individual  
The present invention relates to a method for determining the biological age of human skin, comprising providing human skin cells, determining a degree of methylation of at least two CpG...
DE102017005000A1 Methode zur Genotypisierung von Mausstämmen  
Die vorliegende Erfindung bezieht sich allgemein auf die Analyse genetischer Marker bei Individuen nicht-humanen Ursprungs, insbesondere auf die Genotypisierung von Auszuchtpopulationen von Nagern...
DE102017004108A1 Method for determining the cell number of eukaryotic cells  
The invention relates to a method and a nucleic acid molecule for determining the cell number of eukaryotic cells in a sample. The method according to the invention is based on the analysis of the...
DE102017002092B4 Method for detecting known nucleotide modifications in an RNA  
Method for determining the number and position (locus) of a selected (predetermined), known nucleotide modification in one or more RNAs (including transcriptome), the template RNA (s), comprising...
DE102017107661A1 SH2B adapter protein-3 for the prediction of a bone marrow response and immune response  
The present invention relates to the SH2B adapter protein-3 (SH2B3) for use as a diagnostic marker. Furthermore, the present invention relates to a method for determining the expression of the...
DE102017003312A1 Detection method and device  
The invention relates to a method and a device for the enrichment of cells, cell fragments and molecules from whole blood for a specific detection of at least one contained therein population of...
DE202017104647U1 System for a screening procedure for the diagnosis of haematological neoplasia  
A system (200) adapted or comprising means for performing and / or controlling a screening method for diagnosing hematological neoplasia, the method comprising the steps of: Performing a first...
DE102017204705A1 Mixture of substances and use of a mixture of substances for a polymerase chain reaction  
The invention enters a mixture of substances (10) and its use for a polymerase chain reaction, in particular for a polymerase chain reaction in a microfluidic device (100), wherein the mixture of...
DE102018001873A1 Molecular methods to assess complications after renal transplantation  
Methods of screening for expression of an RNA associated with a complication following renal transplantation include collecting vesicles from urine, isolating vesicle-associated RNA, and examining...
DE102017002092A1 Verfahren zur Detektion von bekannten Nukleotid-Modifikationen in einer RNA  
Das Verfahren umfasst die Reverse Transkription der Template-RNA, die Amplifizierung und Hochdurchsatz-Sequenzierung der dabei gewonnenen cDNAs, das Mapping der sequenzierten cDNAs/Reads zum...
DE112016005844T5 Base sequence determiner, capillary electrophoresis apparatus and method  
A base sequence determining apparatus comprises: (1) a mobility correction unit that outputs a mobility correction signal obtained by mobility correction of a time series signal of each wavelength...
DE112015007082T5 Cell analyzer, apparatus and a cell analysis method using same  
The purpose of the present invention is to provide a single cell analyzer in which both the improvement of nucleic acid capture efficiency and the improvement of cell capture efficiency are...
DE102017200183A1 Nucleic acid-based lateral flow assay for rapid meat species determination  
The present invention relates to a nucleic acid-based lateral flow assay (LFNA) strip for the detection of an analyte nucleic acid molecule in a sample (100), wherein the detection of the analyte...
DE102017109443B3 Method and associated apparatus for producing slurries for building paints with microbiological real-time analysis  
A process for producing at least one slurry for building paints comprising raw materials and / or comprising a premix of various raw materials, characterized in that the at least one slurry is...
DE102016124692A1 Method and system for amplifying a nucleic acid  
The invention relates to a system (10) for amplifying a nucleic acid (22), comprising at least one local heating element (12), which is functionalized with at least one connecting nucleic acid...
DE202018001670U1 Automated portable system for extracting DNA from difficult samples  
Microdevice for the extraction of DNA, characterized in that - The system is suitable for soil samples, bacteria and stool samples.
DE102016222035A1 Microfluidic device and method for analyzing samples  
Microfluidic device (1) for analyzing samples comprising at least two fluidic paths (2, 3) for sample ingestion and at least one detection zone (11) for a detection unit (4) for measuring light,...
DE102016222032A1 Microfluidic device and method for analyzing nucleic acids  
Microfluidic device (1) for analyzing nucleic acids comprising at least: a pumping unit (3) having a pumping volume (4), a filter unit (5) for charging a lysate, and a reaction chamber (6),...
DE112016003948T5 MOLECULAR METHODS FOR EVALUATING A UROTHIAL DISEASE  
The present invention relates to methods for obtaining exosomes and microvesicles (EMV) from urine, for isolating corresponding mRNA, and for studying expression patterns to diagnose and treat...
DE112016003660T5 Preparation of biological sample for testing  
In one embodiment, the method of processing a sample includes selecting a selected sample from a biological test substance, wherein the selected sample is in contact with a first surface of a...
DE102017219909A1 Proteogenomic analysis system and method  
Methods for isolating nucleic acid and protein molecules from a single formalin-fixed paraffin-embedded (FFPE) tissue sample section include lysing the cells of the tissue sample section,...
DE102016221875B4 Stationary phase for detecting a particular analyte in a mixture, uses thereof, and method for detecting a particular analyte in a mixture  
A stationary phase for detecting at least one particular analyte in a mixture is presented. The stationary phase contains a divided into several zones solid phase for the transport of liquid via...
DE102016221875A1 Stationary phase for detecting a particular analyte in a mixture, uses thereof, and method for detecting a particular analyte in a mixture  
A stationary phase for detecting at least one particular analyte in a mixture is presented. The stationary phase contains a divided into several zones solid phase for the transport of liquid via...
DE212016000165U1 microfluidic devices  
A microfluidic device comprising: a disk comprising at least one microfluidic channel path extending radially outward from a center of the disk, the at least one channel path comprising: an inlet...
DE212016000125U1 Oligonucleotide-mediated analysis of biomarkers  
An apparatus comprising: a disc having a plurality of microfluidic channels extending in a radial direction of the disc, each microfluidic channel comprising a plurality of at least one target...
DE102016215128A1 Method for detecting a new variant of the IB virus and kit therefor  
The invention relates to a method for detecting the IB virus, variant IB80, comprising the steps of a) providing a sample potentially containing the IB virus, variant IB80, b) providing a...
DE102016224234A1 MEANS AND METHOD FOR THE DETECTION OF ANALYTES BY MEANS OF MACROSCOPIC GRANULATE PARTICLES  
The present invention relates to magnetically separable polymer-based macro-granules for carrying out immunoassays for the detection of a wide variety of analytes for medical, biological and...
DE102016212834A1 Method, nanoparticle and kit for detection of target structures  
In a method for detecting target structures (210), nanoparticles (10) having at least one immobilized specific capture molecule that can interact with the respective target structure are used. The...
DE102016211357A1 Analysis system and method for performing an analysis  
Embodiments according to one aspect is based on the realization that the integration of a chamber and a semi-transparent heater on two different sides of the chamber allows an analysis system...
DE102016211355A1 Analysis system and method for performing an analysis  
Embodiments in accordance with the principal aspect is based on the realization that a heater having a first geometry, due to the thermal conductivity radiates heat in the direction of the chamber...