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DE102004056794A1 Protein biochip for validation of binders  
The present invention relates to an assembly of proteins containing at least a cDNA expression library and its use as protein biochip, especially for validation of binders and Protein binders, and...
DE102004056794B4 Use of an arrangement and method for validation of binders  
Use of an arrangement of protein binders comprising at least one cDNA expression library for validation or comparison of two or more binders of protein binders, consisting of a unit having a first...
DE10256042B4 A process for the selection of cells that produce the specific binding molecules  
process for the selection of cells expressing specific binding non-conjugate non-fusion molecules full a) available make of cells, at least one potentially specific binding Not conjugate nonfusion...
DE19653685B4 In vitro cell system vascular smooth muscle for pharmacological and physiological studies  
In vitro test system for pharmaceutical and physiological studies, characterized by the use of a vascular smooth muscle in vitro cell system, the by transferring pluripotent embryonic stem cells...
DE102005028117A1 Diagnosis and treatment of autophagy-associated diseases  
It new members of the WIPI family of proteins are provided which valuable targets for the modulation of the cellular Autophagy and thus for the diagnosis and treatment of autophagy-associated...
DE10353785B4 Method and apparatus for detection of different cell types of cells in a biological sample  
process for the detection of various cell types of cells in a biological Sample (109), comprising the steps of: (A) providing a Image (1201 to 120n) the biological sample (109); (B) normalizing...
DE10062623B4 Three-dimensional skin model  
process for the propagation of dermal fibroblasts, wherein the dermal fibroblasts embedded in a three-dimensional, gel-like biomatrix containing 3.5 to 4.5 mg collagen / ml in buffered...
DE3571648C5 Monoclonal antibodies to human breast cancer, their production and use, hybridomas for their preparation and the preparation of these hybridomas.  
monoclonal Mouse antibody, of the (A) binds a human breast cancer antigen that of a Control antibody is also attached, by one of the ATCC HB8484 and HB8696 available Hybridomas is formed; (B) has...
DE102004052889A1 Screening method for early detection of cerebral vasospasm  
The Invention relates to screening methods and test systems for in vitro diagnostic and detection of an increased Risk of vasospasm in a patient. In addition, the invention describes the use of...
DE10320602B4 A method for identifying a possible modification of at least one biological parameter using young and old living cells  
process to identify a possible Modification of at least one biological parameter, which due to is changed from cell aging, which is characterized in that it comprises: comparative Transcriptome...
DE10244129B4 H + -K + -ATPase assay  
process for identifying an active complex which an enzymatic modified property of Wirkortkomplexes which a type a H+-K+-ATPase Protein contains, comprising the steps of: (A) providing a plurality...
DE10320633B4 A method of identifying a possible modification of at least one biological parameter using living cells that were exposed to a stimulus, and living cells that were not exposed to this stimulus  
process to identify a possible Modification of at least one biological parameter, which characterized is characterized in that it comprises: the comparative transcriptomic and / or comparative...
DE102004048462A1 Model system for the testing of pharmaceutical preparations for efficacy in inflammatory processes in the nervous system  
The Invention relates to a method for testing of active ingredients in pharmaceutical preparations for their neuroprotective or entz√ľndungsmodulatorische Effect. The combination of cytokines in...
DE102004048462B4 Model system for the testing of pharmaceutical preparations for efficacy in inflammatory processes in the nervous system  
Out Tissues or organs of a mammal obtained, ex vivo on porous Membranes with a pore size ‚Č• 0.02 microns at a physiologically acceptable pH in the presence of a culture gas maintained in culture in...
DE102004048397B4 Type SGLT1 protein assay  
process for identifying an active complex which an enzymatic modified property of Wirkortkomplexes which a type contains a SGLT1 protein, comprising the steps of: (A) providing a plurality of...
DE102004048397A1 Type SGLT1 protein assay  
Proposed is a method for identifying an active compound, which modifies an enzymatic property of SGLT1 protein. It Primary carriers are provided, containing the SGLT1 protein in the region of...
DE102004048396B4 Type EAAC1 Protein Assay  
process for identifying an active complex which an enzymatic modified property of Wirkortkomplexes which a type contains a EAAC1 protein, With the steps of: (A) providing a plurality of primary...
DE102004048396A1 Type EAAC1 Protein Assay  
Proposed is a method for identifying an active compound, which modifies an enzymatic property of EAAC1 protein. It will Primary support provided, containing the EAAC1 protein in the region of...
DE102004048391A1 Type PepT1 Protein Assay  
The Invention relates to a type PepT1 protein assay and in particular a method for identifying a substrate and / or a Modulator of the PepT1 protein.
DE102004048391B4 Type PepT1 Protein Assay  
process for identifying an active complex, which enzymatic modified property of Wirkortkomplexes which a type contains a PepT1 protein comprising the steps of: (A) providing a plurality of primary...
DE102005044530B4 Method for gender selection of mammalian spermatozoa  
A method for sorting non-human mammalian spermatozoa, comprising the steps of a. staining intact, viable spermatozoa, except human spermatozoa which were obtained from a male mammal to stain with...
DE102004046327A1 Detecting nucleocytoplasmic shuttling, by injecting anti-reporter gene antibody into nucleus or cytoplasm of transformed cell expressing chimeric reporter gene fusion protein and detecting reporter gene  
Detection of transport between the nucleus and cytoplasm in a transformed cell expressing a chimeric reporter gene fusion protein involves injecting an anti-reporter gene antibody into the nucleus...
DE102004046327B4 A method for detecting nucleocytoplasmic transport processes  
process for detecting a transport of GFP fusion proteins between nucleus and cytoplasm in a transformed, GFP fusion proteins expressing cell, characterized in that GFP fusion proteins in the core...
DE102004044048A1 Biochemical characterization of objects via reaction products from cellular systems, especially identifying pyrogens using blood as indicator, by enzymatic assay including immobilization on magnetic particles  
Biochemical characterization of cells or substances (I) by detection and characterization of reaction products from cellular systems, is new. Biochemical characterization of cells or substances...
DE10105420B4 In vitro cell culture of interaction system for drug testing and development  
In vitro cell culture system interaction of a first cell culture consisting from pelleted and precultured cells, except human embryonic stem cells and germ-cells, and the second from a Culture,...
DE102005003457B4 Method and kit of parts for the microbiological determination of Vitamen  
Method for quantitative microbiological determination of individual vitamins, amino acids or other essential substances in a substance mixture, characterized in that in the culture vessel for...
DE102005003457A1 Method and kit of parts for the microbiological determination of Vitamen  
test kit and process for the microbiological determination of vitamins in Food and fluids using microtiter plates and automatic reading devices for the routine analysis. The method is...
DE102004025224B4 Quantitative dermination of hydrogen sulfide in gases, e.g. for monitoring waste gases, using flow system with biosensor comprising sulfur-oxidizing bacteria immobilized on oxygen sensor and/or pH sensor  
Selective quantitative determination of hydrogen sulfide (H2S) in a gas phase is carried out in a flow system using a biosensor comprising living chemolithoautotropic sulfur-oxidizing bacteria...
DE102004044201A1 Composition for detecting and differentiating renal tumors, containing DNA probes for specific chromosomes, to detect abnormalities indicating clear cell, chromophilic, chromophobic or oncocytoma tumors  
A composition (I) for detecting and differentiating renal tumors, comprising investigating cells from suspected tumor tissue in the kidneys for genetic abnormalities, comprising DNA probes for...
DE19620250B4 Microbial sensor for determining the biochemical oxygen demand  
device for determining the biochemical oxygen demand (BOD) with a physical transducer and this immobilized microorganisms characterized in that the microorganisms of the salt-tolerant and...
DE10256669B4 Mixture of at least two fusion proteins as well as their preparation and use  
protein mixture comprising: a) at least a first fusion protein comprising: i) a protein or protein fragment, ii) an interaction domain and iii) a protein translocation sequence which effects that...
DE102004040370A1 A method for identifying atypical p-ANCA  
The Invention relates to methods for the identification of atypical p-ANCA and therefor Kits suitable and the use of these methods for the diagnosis of chronic inflammatory Bowel disease and...
DE102004039628A1 Carrier plate for carrying out functional tests on biological cells, and methods for coating the carrier plate  
The This invention relates to a method for coating a support plate to perform out functional tests on biological cells, a carrier plate to perform out functional tests on biological cells and the...
DE102004033905A1 Cytological investigation method, especially for gynecological screening, e.g. in early diagnosis of cervical carcinoma, by determining nuclear chromatin content, optionally followed by other tests  
A cytological investigation method comprising: (a) determining the nuclear chromatin content of cells originating from a cell sample by conventional methods; (b) comparing the result with a...
DE102004031560A1 Sepsis Diagnostic Test  
The This invention relates to a method for the extracorporeal qualitative or semi-quantitative determination of the amount of indicators for SIRS or sepsis in the blood, blood serum, blood plasma,...
DE10306089B4 Method and test kit for the determination of neuro immunological health disorders  
process for determining neuroimmunological health disorders, characterized in that in the lymphocyte or lymphoid cells of patients in vitro inflammatory or proinflammatory Cytokines (Zf) And...
DE102004032872A1 A method for identifying fungicidally active compounds based on thymidylate kinases  
The This invention relates to a method for identifying Fungicides, the use of thymidylate kinase to identify of fungicides, the use of inhibitors of the thymidylate kinase as fungicides and method...
DE10043470B4 A method for identifying cell-specific proteins  
process for the identification of cell-specific proteins with a first Step: a) determination of cell specific topological Protein combination patterns of n cells at the single cell level, thereby...
DE102004031116A1 Method of finding relevant substances pain using pain-relevant proteins  
The Invention relates to a method for discovering pain-related Substances using the proteins KIAA0378, BAB31214 / Q9BU64, OPA1 / KIAA0567, CPG2 / KIAA1756, LETM1, PID12832121 / FLJ20420 and PGRL...
DE10226675B4 A method for testing the hormonal effect of substances  
process for testing the hormonal effect of substances, in which a. Cells transfected with two vectors, wherein the one Vector DNA for the androgen receptor or a fragment thereof, and the other...
DE10226674B4 A method for testing the hormonal effect of substances  
process for testing the hormonal effect of substances, in which a) Cells transfected with two vectors, wherein the one Vector DNA for the androgen receptor or a fragment thereof, and the other...
DE10246811B4 A process for the identification and mitigation of the risk of breast cancer by the micronucleus test in binuclear cells  
process for the determination of sporadic breast cancer risk, the following steps full: (1) Fixed a lymphocyte cell culture from heparin-treated peripheral blood, (2) mitogenic stimulation of the...
DE102004020836B3 Detection, removal, analysis and recovery of noble and other heavy metals in aqueous medium, useful for treating ground and surface water, sewage and industrial waste liquor, uses mixture of 3 strains of Mucor hiemalis fungus  
Detection of heavy metals (I) in aqueous medium (II) and removal of (I) from (II) comprises: (a) contacting liquid (II) containing (I) with a mixture (III) of the fungi Mucor hiemalisstrains EH8,...
DE10209245B4 Device and method for the detection of microorganisms  
Micromechanical Arrangement for detecting biological activity of microorganisms with at least a micromechanical cantilever and means for determining changed Cantilever properties, characterized in...
DE102004045186B9 Liposomes, which stimulate the intracellular penetration of active substances, their use for the preparation of topical pharmaceutical and cosmetic compositions containing these liposomes as well as a screening method for finding substances for stimulating the intracellular penetration  
Use of liposomes, characterized in that it comprises in its structure a substance or a mixture of substances comprising at least partly, which is / are capable of the intracellular penetration of...
DE102004045186A1 Hydrated lamellar phases or liposomes, containing a fatty mono-amine or a cationic polymer that promotes intracellular penetration, and cosmetic or pharmaceutical compositions comprising these, as well as screening methods for such a substance  
The Invention relates to novel hydrated lamellar phases or liposomes, which either polyethyleneimine or a substance which the intracellular penetration stimulates containing selected from the...
DE102004045186B4 Liposomes, which stimulate the intracellular penetration of Wirkstofen, their use for the preparation of topical pharmaceutical and cosmetic compositions containing these liposomes as well as a screening method for finding substances for stimulating the intracellular penetration  
Use of liposomes, characterized in that it comprises in its structure a substance or a mixture of substances comprising at least partly, which is / are capable of the intracellular penetration of...
DE102004025224A1 Quantitative dermination of hydrogen sulfide in gases, e.g. for monitoring waste gases, using flow system with biosensor comprising sulfur-oxidizing bacteria immobilized on oxygen sensor and/or pH sensor  
Selective quantitative determination of hydrogen sulfide (H2S) in a gas phase is carried out in a flow system using a biosensor comprising living chemolithoautotropic sulfur-oxidizing bacteria...
DE102004025130A1 Method and apparatus for investigating on Sludgeablagerungen materials for prostheses and joint endoprosthesis  
The Method and apparatus are used for the investigation of Sludgeablagerungen on Materials for coating stents. At least one coated stent is placed in an incubation vessel, which is at least...
DE102004022435A1 Process for the preparation of soluble MHC proteins  
The invention relates to a recombinant, purified MHC protein, which is substantially the same conformation, functional activity and the Binding properties for specific antibodies and having...