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DE102011076238A1 Apparatus and method for optical analysis and specific isolation of biological samples  
The invention relates to a method for the detection of cells in a liquid sample, comprising the steps of: i) the membrane is arranged flat on the transparent supporting body (3) filtering the...
DE102011118949B3 Combined method for differential diagnostic detection of bacteria of e.g. Mycobacterium tuberculosis complex and Chlamydophila pneumoniae, where the method is performed on the basis of a real-time PCR using labeled probes  
Combined method for differential diagnostic detection of bacteria of Mycobacterium tuberculosiscomplex and the atypical pneumonia pathogens of Chlamydophila pneumoniae, Mycoplasma pneumoniae,...
DE102011078184B3 Biotransformationssensor  
The present invention relates to a device for evaluating at least one chemical substance in respect of their toxicity for living cells and their respective use. In a flow system, a...
DE102012013810A1 Detecting reproducible cells, which exhibit a cellular response during contact with a product mixture  
Detecting reproducible cells, which exhibit a cellular response during contact with a product mixture, is claimed.
DE102012013810B4 Detection of viable cells that respond to a product mixture  
The invention relates to a detection of viable cells that respond to a product mixture. He also provides a library includes at least 1,000 different single-product mixtures.
DE102012003714B3 Detecting natural or synthetic, proliferative cells, genetically programmed or de novo programmed, useful for functioning as input-output transformation imitating reproductive organ activity, comprises e.g. carrying out cellular reaction  
Detecting natural or synthetic and proliferative cells, genetically pre-programmed or de novo programmed for functioning as an input-output transformation imitating a reproductive organ activity,...
DE102011016191A1 Localization of primary tumors of metastasis tissue samples, comprises analyzing fully isolated metastasis tissue samples for the expression level of the specified genes, and concluding the localization of the primary tumor in the patient  
Localization of primary tumors of metastasis tissue samples, comprises analyzing fully isolated metastasis tissue samples for the expression level of the genes CD302, PPWD1 and ABHD14B, and...
DE102011005600A1 Detection of organisms and determining the resistance by mass spectrometry  
According to the invention the detection of microorganisms by this au applied for a substrate (eg. As a nutrient medium) and incubated (incubated) and subsequently the (gaseous) metabolites of...
DE102011012060A1 Mass spectrometric determination of the inhibitory effect of compounds against beta-lactamases  
The invention provides methods for determining the inhibitory effect of a substance compared to beta-lactamases prepared in which the substance is a beta-lactamase and a substrate having a...
DE102011076221B3 Automated CTC detection  
The invention is in the field of in vitro diagnostics and relates to a method and Andordnung for detecting living, circulating or disseminated cells from body fluids (eg blood, urine z.) Or offset...
DE102011003101A1 A method for detecting a Plasmodieninfektion  
The invention relates to a method for detecting a Plasmodieninfektion in a patient's blood sample, a differential analysis of polymorphonuclear neutrophil granulocytes is performed in the sample...
DE102010060498A1 Isolation and functional identification of whole cells  
The invention relates to methods for labeling, identifying and isolating a target cell, wherein the target cell is contacted with a capture compound in a first step, which is a small molecule,...
DE102010060498B4 Isolation and functional identification of whole cells  
The invention relates to a method for isolating a target cell in which the target cell is contacted with a capture compound, which has a selective binding to the cell surface, small molecule...
DE112006001097B4 System for functional analysis of polypeptides and analysis methods for polypeptides  
The present invention discloses a polypeptide-inspection system which includes a non-mammalian cell cultured in a non-mammalian cell culture medium or in a non-mammalian cell culture expressing a...
DE102010041912B3 A method for the diagnosis and / or prognosis of cancer by analysis of the mechanical properties of tumor cells  
The invention relates to a method for diagnosis and / or prognosis of cancer diseases, for the diagnosis of the place of origin of tumor cells, for the optimization of therapy of cancer patients,...
DE102010047069A1 Differential diagnosis of pancreas adenomas  
A method for in vitro diagnosis of a Pankreasadenoms, comprising the steps of: incubating a sample obtained from an individual with at least one of antibodies containing one of the genes selected...
DE102010037622A1 A method for detecting, differentiating and quantifying T cell populations by means of reverse transcription quantitative real-time PCR (RT-qPCR) technology  
The present invention relates to a method for the detection, differentiating and quantifying T cell populations, comprising the steps of a) contacting a first aliquot of a body fluid of an...
DE102010033565A1 Marker for the determination of chondrocytes  
The present invention relates to a marker for in vitro prediction of identity, purity, or potency of chondrocytes, wherein the marker is selected from at least one of the following: FLT-1, BSP-2,...
DE102010033565B4 Marker for the determination of chondrocytes  
Use of a marker for the in vitro determination of the pharmaceutical identity, purity or potency of chondrocytes, characterized in that the marker is selected from at least one of the following:...
DE102010033105B4 Mass spectrometric diagnosis of sepsis without blood culture  
A method for the identification of microbes in body fluid comprising the steps of: a) dissolving the Human particles in the body fluid by a surfactant or destruction of the human particles by...
DE102010033105A1 Mass spectrometric diagnosis of sepsis without blood culture  
The invention relates to methods and apparatus for rapid detection and rapid mass spectrometric identification of microbial pathogens in blood, but also in other body fluids. The invention...
DE102010032203A1 Method and apparatus for passive separation and sorting of drops, particularly in a microfluidic system, by use of non-optical markers for reactions within the drop  
The present invention particularly relates to methods of passive separation and sorting of droplets by use of non-optical markers for reactions within the drops. Such a method preferably comprises...
DE102011077511A1 Detecting toxins and/or pyrogens, comprises incubating ciliates of the genus Tetrahymena with a sample and testing, and the treated ciliates change the expression and/or release at least one endogenous protein  
Detecting toxins and/or pyrogens, comprises incubating ciliates of the genus Tetrahymenawith a sample and testing, where the treated ciliates change the expression and/or release at least one...
DE102011077511B4 A method for the detection of toxins and / or pyrogens based on changes in protein expression in ciliates of the genus Tetrahymena  
A method for the detection of toxins and / or pyrogens, characterized in that ciliates of the genus Tetrahymena are incubated with a sample and is then examined whether it arrived in the treated...
DE102010024898A1 Gene expression analysis for the characterization and identification of genotoxic compounds  
A method for testing compounds to genotoxic and / or progenotoxisches potential comprising the steps of: (a) providing a cellular system, which at least for the expression of the genes GLS2, IER5,...
DE102010024898B4 Gene expression analysis for the characterization and identification of genotoxic compounds  
A method for testing compounds to genotoxic and / or progenotoxisches potential comprising the steps of: (a) providing a cellular system, which at least for the expression of the genes GLS2, IER5,...
DE102010024503A1 Detecting infection with Mycobacterium avium subsp. paratuberculosis in ruminant, comprises quantifying marker in sample and comparing sample to be analyzed with reference values and values of positive and/or negative control  
Detecting infection with Mycobacterium avium subsp. paratuberculosis(MAP) in a subject, preferably in a ruminant, comprises: (a) providing a sample from a subject; (b) quantifying a marker in the...
DE102010023156B4 In vitro assay system for viral infections  
Multilayer biological in vitro tissue containing - Dermis layer containing a collagen biomatrix with fibroblasts embedded therein and - Epidermis, containing epithelial cells, characterized in...
DE102010023156A1 In vitro assay system for viral infections  
The invention relates to a multilayered biological tissue in vitro comprising: dermis layer containing a collagen biomatrix with then embedded fibroblasts and epidermal layer, containing...
DE102010017396A1 Legionella Test  
The present invention relates to an apparatus and a method for qualitative and / or quantitative determination of Legionella (Legionella) in water or aqueous solutions. With the invention a...
DE102010009339A1 Detecting toxins and pyrogens, comprises carrying out immune reaction of Tetrahymena on the substance to be tested, incubating and detecting the immune response by chemical color reaction for the detection the nitrogen monoxide  
Detecting toxins and pyrogens, comprises carrying out the immune reaction of the genus Tetrahymenaon the substance to be tested, incubating for at least 1-3 hours, where the immune response is...
DE102010023837A1 Isolation of mesenchymal stem cells  
The present invention relates to the use of a peptide selected from the group comprising laminin-1, collagen 1, collagen-3, Collagen 4, tenascin, thrombospondin-1, osteopontin, fibronectin,...
DE102010010372B3 Kit, useful e.g. for identification of pathogens of Mycobacterium tuberculosis complexes, comprises means for analyzing sequences in genes Rv0557, Rv2628, Rv2629 and Rv1811, and the promoter sequence of Rv2946c  
Kit comprises means for analyzing sequences in the genes Rv0557, Rv2628, Rv2629 and Rv1811, and the promoter sequence of Rv2946c, where the means in Rv2628, Rv2629, Rv1811 and Rv0557 are suitable...
DE102010019059A1 Sensors for intracellular metabolite detection  
The present invention relates to a comparison with its wild type GM cell comprising a sequence coding for a protein autofluorescence gene sequence, wherein expression of the protein...
DE102010010526A1 Determining fertility of sperm, comprises labeling sperm with fluorescent dye, recording fluorescence microscopic images with exposure time adjusted to speed of movement of sperm, and analyzing fluorescence microscopic images  
Determining the fertility of sperm, comprises labeling the sperm with at least one fluorescent dye, recording the fluorescence microscopic images with the exposure time adjusted to the speed of...
DE102010007243B4 Optimizing therapy for cancer patients by testing of therapeutic combinations using in vitro tests (additional)  
Currently there is no diagnostic that can evaluate different treatment options for a patient in a test system. In particular, the effects of different nutrient rates and oxygen rates (modified by...
DE102010007243A1 Optimizing therapy for cancer patients by testing of therapeutic combinations using in vitro tests (additional)  
Currently there is no diagnostic that can evaluate different treatment options for a patient in a test system. In particular, the effects of different nutrient rates and oxygen rates (modified by...
DE102009046525B4 A method and kit for the testing of various selected materials and / or surface structures for the culture of cells  
A method for testing different, selected materials and / or surface structures for the culture of cells and / or microorganisms comprising the steps of: i) providing a plurality of test different...
DE102009046525A1 A method and kit for the testing of various selected materials and / or surface structures for the culture of cells  
The present invention relates to a method for testing different, selected materials and / or surface structures for the culture of cells and / or microorganisms comprising the steps of: i)...
DE102009041254A1 Spontaneously contracting fish cell aggregates, their use and processes for their production  
The invention relates to an in vitro method for the production of spontaneously contracting fish cell aggregates, the fish cell aggregates obtainable thereby and their use, in particular for the...
DE102009058634A1 toxicity test  
Teratoma formed from embryonic stem cells, for use in a toxicity test, in particular for testing the embryotoxicity of substances.
DE102010027827B3 Method and means for identifying substances that inhibit the IgE production  
The invention relates to the field of biomedical and pharmacological research, especially in the field of immunology, allergy and autoimmune diseases. The inventors have shown that SWAP-70 a...
DE102009047549B4 Method and means for patient- and malignomspezifischen detection of malignant cells  
A process for preparing a diagnostic agent for specific detection of malignant cells of an individual comprising the steps of: a.) High resolution display amplified genomic segments in an isolated...
DE102009047549A1 Preparing diagnostic agent, to detect malignant cells, comprises imaging amplified genomic region in tumor sample, duplicating and sequencing fusion region of genomic region within amplicon with amplicon-fusion region and providing probe  
Preparing a diagnostic agent comprises high-resolution imaging of amplified genomic regions in an isolated tumor sample using fine-tiling array, optionally after previous whole genome analysis,...
DE102009047146B4 A method of predicting the response of a tumor to a therapeutic measure  
A method of predicting the response of a disease caused by a solid epithelial tumor malignancy of a patient to a therapeutic measure, said epithelial tumor cells are taken from a body fluid of...
DE102009047146A1 A method of predicting the response of a tumor to a therapeutic measure  
The invention relates to a method for predicting the response of a disease caused by a solid epithelial tumor malignancy of a patient to a therapeutic measure, said epithelial tumor cells are...
DE102009043426A1 Device and method for obtaining, for the detection and analysis of cells in a microfluidic system  
The invention relates to a device for obtaining, for the detection and, optionally, for the analysis of cells in a biological fluid with a microfluidic system comprising a) at least one...
DE102009043426B4 Device and method for obtaining, for the detection and analysis of cells in a microfluidic system  
An apparatus for obtaining and for the detection of cells in a biological fluid with a microfluidic system, comprising a) at least one microfluidic channel with a small cross section, which is...
DE102009054057A1 Screening methods for agents for the prophylaxis and therapy of neurodegenerative diseases  
Disclosed is a screening method for agents for the prophylaxis and therapy of neurodegenerative diseases, preferably Alzheimer's disease, wherein the active compounds inhibit the transport of Aβ42...
DE102009054098A1 Detection of mycobacteria and their resistance genes  
The invention relates to an in vitro method for the detection of DNA from tuberculosis bacteria or mycobacteria or its DNA, comprising the steps of:· Providing a sample containing mycobacteria,·...