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DE102013221452B3 A method for determining the efficacy and / or specificity of an active substance  
The invention relates to a method for determining the specificity and / or efficacy of an antibody directed against specific target cells in a mixed culture active substance, the target cells and...
DE102014109570A1 A method for establishing a damage model and method for determining the expected deterioration of an aqueous protein solution by freezing processes  
The invention relates to a method for establishing a damage model and method for determining the proportion of a dissolved in an aqueous solution protein, for which due to a freezing process an...
DE202014104644U1 System for the diagnosis of colorectal cancer  
System for diagnosing colon cancer, comprising: a detection device for detecting an immunomagnetic reduction (IMR) signal in a sample of a test subject as a result of conjugation of a...
DE202011110503U1 Hanging drop devices and systems  
System, comprising: a) at least one array plate, wherein said at least one array plate has a top and a bottom and a plurality of holes therein, wherein each of the plurality of holes has a top and...
DE202011110503U9 Hanging drop devices and systems  
Hanging drop array plate (1, 8, 161), comprising: a top (10, 172) and a bottom (9, 173), wherein the top surface (10, 172) is limited by an edge or multiple edges, a plurality of holes (6, 171),...
DE102013007295A1 Electrophysiological measurement arrangement and electrophysiological measuring methods  
The present invention relates to an electrophysiological measuring system (100) as well as an electrophysiological measuring method in which a support (12) of a carrier material (12 ') and an...
DE102013007295B4 Electrophysiological measurement arrangement and electrophysiological measuring methods  
Electrophysiological measurement arrangement (100), with a carrier (12), which at least in its interior (12i) of a carrier material (12 ') having a given composition, and with an aperture area...
DE102014005549A1 A system for non-contact monitoring of reaction vessels with electronic bearing holder, preparation of suitable vessels and monitoring technology  
Creation of an integrated reaction vessels (RG) -, experiment-, data and knowledge management system for the laboratory automation, wireless identification, management, analysis and measurement of...
DE102013106462B3 Detection methods for the detection of bacteria, processes for the production of fusion proteins and fusion protein  
The invention relates to a detection method for the detection of bacteria (10), comprising the steps of a) specific enrichment of a bacterial surface protein (32) at an accumulation structure...
DE102014201528A1 In vitro method for prognostic evaluation of the likelihood of successful implantation and / or transplantation  
The invention relates to a prognostic in vitro method for assessment of tissue regeneration capacity and / or the cellular potency and / or the likelihood of successful implantation and / or...
DE102013004805A1 Electrical method for the detection of changes in molecular interactions  
a method and a sensor for detecting changes in molecular interactions in general, and for detecting an analyte in a sample, in particular on the basis of a detection of an electrical conductivity...
DE102013203161A1 Body fluid sensor and method for measuring the properties of body fluids  
It will be a body fluid sensor and a method for measuring a body fluid specified, comprising: - A housing for receiving a cell culture with living cells, - Means for feeding the body fluid to the...
DE102013003037A1 Software for bacteriological risk assessment, in which complex environmental stimuli, are projected and programmed under the aspects of infection ecology to different species of bacteria in conventional software  
Software for bacteriological risk assessment is claimed. The complex environmental stimuli, preferably supply of nutrients, oxygen concentration, temperature, pH, humidity, presence of...
DE102013001953A1 Use of pyridinium and viologen dendrimer of higher generation for active ingrdient transport and transport of dyes and fluorescent markers in eukaryotic cells (mammalian)  
Use of pyridinium and viologen dendrimer of 1, 2 or higher generation for active ingrdient transport and transport of dyes and fluorescent markers in eukaryotic cells (mammalian), is claimed. The...
DE102013225894A1 Selecting keratinocytes for producing three-dimensional epidermal models, involves providing lysate from keratinocytes of epidermal sample, determining gene expression of four different genes from cell lysate, and selecting keratinocytes  
Selecting keratinocytes for producing three-dimensional epidermal models, involves: (a) providing a lysate from the keratinocytes of an epidermal sample; (b) determining the gene expression of...
DE102013225893A1 Selecting keratinocytes for producing three-dimensional epidermis model, comprises e.g. labeling three different biomolecules of cell homogenate of epidermis sample keratinocytes and identical biomolecules of homogenate of reference sample  
Selecting keratinocytes for producing three-dimensional epidermis model for determining skin irritation, comprises (a) providing a cell homogenate of keratinocytes of an epidermis sample, (b)...
DE102012112600A1 A method for determining the level of immunosuppression in a subject and application thereof  
The present invention relates in a first aspect, a method for determining the level of immunosuppression in a subject that has been treated with an immunosuppressive agent. Furthermore, a method...
DE102012024749A1 Tumor prevention and therapy by inducing Tumorseneszenz  
The present invention relates to a combination of at least two different substances, one of which activates a STAT1 signaling cascade, and the other the TNFR1 / CD95 signaling cascade activated to...
DE102013109065A1 Arrangement for quick diagnosing tuberculosis and to test the pharmaceutical effect  
The invention relates to an arrangement for quick diagnosing tuberculosis and to test the pharmaceutical effect that a gene array assembly (20) from a test range for Mycobacterium tuberculosis...
DE102013109065B4 Arrangement for quick diagnosing tuberculosis and to test the pharmaceutical effect  
The invention relates to an arrangement for quick diagnosing tuberculosis and to test the pharmaceutical effect that a gene array assembly (20) from a test range for Mycobacterium tuberculosis...
DE102012020496A1 Invitro diagnosis and/or early detection of neurofibromatosis type 1 and/or neurofibromatosis type 1-associated tumor from sample of a patient for treating the patient with the tumor, comprises detecting protein or its fragment in sample  
Invitro diagnosis and/or early detection of neurofibromatosis type 1 (NF1) and/or an NF1-associated tumor, comprises detecting at least one protein consisting of e.g. tumor necrosis factor-alpha...
DE112012002557T5 Strain improvement and process optimization in a mixed two-stage fermentation for the production of Vitamin C.  
A method for improving the yield of the vitamin C precursor 2-keto-L-gluonic acid by means of the mixture of strains to establish a subculture as well as the improved interaction between two...
DE102013209312B3 Kit, useful for in vivo detection of extracellular primary signal by interspecies communication, comprises yeast cells of different species, where yeast cells comprise sensor-cell, and actuator-cells comprising e.g. receptor for pheromone  
Kit comprises yeast cells of different species comprising (a) a sensor-cell of a first type comprising a gene, which leads to the synthesis of a pheromone and is provided under transcriptional...
DE102012220083B3 Method and system for direct, non-radiative energy transfer by liquid phase boundaries  
The invention relates to a method and system for non-radiative energy transfer at a phase boundary a liquid-liquid multiphase system having an organic phase and an aqueous phase. The system...
DE102012016885A1 Supporting preservation of insect population, comprises determining lethal effect of product unit on insect population, determining insect population difference, actual insect population and desired insect population in predetermined area  
Supporting the preservation of the insect population, comprises: determining the lethal effect of a product unit on an insect population, determining a difference in the insect population based on...
DE102013010528B3 Creating database for preliminary estimation of effectiveness of cytostatic active substance in chemotherapeutic treatment of tumor, by incubating tumor cells of previously removed tumor tissue sample from patients  
Creating a database for a preliminary estimation of the effectiveness of a cytostatic active substance in the chemotherapeutic treatment of a tumor, preferably malignant tumor, a particular...
DE102013204543B3 Detecting ions and/or ion complexes, comprises e.g. mixing solution containing nanoparticles and solution containing isolated bacterial envelope proteins, contacting mixture with ion complexes, and detecting change in optical properties  
Detecting ions and/or ion complexes, comprises (a) providing a solution containing nanoparticles, (b) providing a solution containing isolated bacterial envelope proteins, (c) mixing the above two...
DE102013010253B3 Detecting natural or synthetic cells e.g. de novo programmed cells to organism-crisis situation activity imitative input-output transformation, comprises performing cellular reaction upon contact with mixture of e.g. folic acid, vitamin B12  
Detecting natural or synthetic, proliferative cells which are genetically programmed or de novo programmed for function of an organism-crisis situation activity imitative input-output...
DE102010064525B3 Marking target cell comprises contacting cell surface of target cell with particle and binding cell surface at particle, where particle comprises capture compound comprising e.g. photoactivatable reactivity- and sorting/marking-function  
Marking a target cell comprises contacting the cell surface of the target cell with a particle and binding the cell surface at the particle, or contacting the target cell with the capture compound...
DE102013106380A1 Liquid-based sensor device, useful for detecting the presence of analyte e.g. bacteria cell, comprises substrates, liquid crystal layer, and phospholipid layer, reaction layer, electrodes, and insulating layer and/or alignment layer  
The liquid-based sensor device comprises a first substrate, a liquid crystal layer disposed on the first substrate, and a phospholipid layer disposed on the liquid crystal layer. The device does...
DE102012210598A1 Method and arrangement for the detection of cells in a cell suspension  
An arrangement for the quantification of cells under differentiation at least two different sizes of cell types and / or cell conglomerate types specified in a cell suspension with a magnetic...
DE102012210055B4 Demonstration of the viability of biological samples  
A method for assessing the viability of one or more biological samples comprising a) providing the biological sample (s) to be examined, b) incubating the biological sample (s) provided with a)...
DE102012210055A1 Proof of viability of biological samples  
The invention relates to a method, a use and a kit for detecting the viability (viability) of biological samples using ageladine A. The invention is advantageous to detect the viability of...
DE102012011648A1 Analysis of microbes from microcolonies by MALDI mass spectrometry  
The invention relates to methods for mass spectrometric identification of microbes, in particular the cell disruption of microbes and the preparation of microbial proteins for spectra recording...
DE102012011648B4 Microbial microbial analysis by MALDI mass spectrometry  
A method for the mass spectrometric analysis of microbes from colonies on a nutrient surface in a mass spectrometer, comprising the steps of: (a) microbes are disrupted on the nutrient surface,...
DE102012011647A1 Analysis of microbes from microcolonies by MALDI mass spectrometry  
The invention relates to methods for the mass spectrometric analysis of microbes, in particular to a transfer method of microbes that are required to be identified from agar plates onto mass...
DE102012104688A1 An optical sensor element  
The invention relates to an optical sensor element with indicators, selected from identical or different luminescence-active agents, and indicator protectors, a sensor with at least one such...
DE102012012336B3 Detecting and evaluating effects of substance to be tested on earliest development of vertebrates, involves selecting transgenic fish embryo reporter line, providing fish embryos of selected line, and marking cell nucleus of fish embryos  
Detecting and evaluating effects of at least one substance to be tested on the earliest development of vertebrates, comprises (a) selecting at least one suitable transgenic fish embryo reporter...
DE102012014981B3 Method for differentiating between living and dead cells  
The present invention relates to a method for the quantitative determination of live and dead cells in a biological sample. The inventive method is based on determining the amount of DNA in the...
DE102011122891B4 Fermentation medium that is free of animal components for the production of diphtheria toxoids for use in the vaccination of humans  
A process for preparing a diphtheria toxoid, which comprises: (I), anz├╝chtet a strain of Corynebacterium diphtheriae expressing a diphtheria toxin in a fermentation medium; (Ii) diphtheria toxin...
DE102011119953A1 Individualized skin treatment comprises e.g. applying and removing adhesive tape on skin surface, obtaining adherent biological material, determining expression and/or activity of differentiation marker, and treating with cosmetic products  
Individualized skin treatment comprises (a) applying an adhesive tape on a selected skin surface, (b) removing the adhesive tape from the skin, (c) obtaining adherent biological material, (d)...
DE202012100019U1 T cell frequency  
Product prepared by a process for producing a Untersuchungsreagens, wherein an unfolded protein, in particular an unfolded MHC class I protein, in a starting solution a replacement element is...
DE102011053741A1 Method for testing the self-healing by the immune system of an infected with human papillomavirus human  
The invention relates to a method for testing the self-healing by the immune system of a with human papillomavirus (HPV) infected people with the following steps: 1) removal of at least one sample...
DE102011082432A1 A method for determining the age haired mammals  
A process that allows us to assess the age hairy mammals and proposals for products based on the result and can support advertising claims for products, comprising the steps of a) the mammal takes...
DE102011080992A1 Using Mad2l2 Stratification as in the treatment of breast tumors with new pan-CDK inhibitors  
The invention relates to the use of Mad2l2 Stratification as in the treatment of breast tumors with new pan-CDK inhibitors of the formula (I).
DE102011080991A1 Using CCNE2 Stratification as in the treatment of breast tumors with new pan-CDK inhibitors  
The invention relates to the use of CCNE2 Stratification as in the treatment of breast tumors with new pan-CDK inhibitors of the formula (I).
DE102011106717B4 Device and method for the analysis of volatile organic compounds in gaseous samples  
A method for classification of gaseous samples, characterized in that the sample is added to a defined volume and chromatographed, generated from the sample spectrograms stored in a database and...
DE102011106547A1 Method and device useful e.g. for inactivating bacterial species comprising Escherichia coli in whole blood, where method comprises generating electromagnetic or electric field by applying low direct current and inactivating physiologically  
Method and device for effectively inactivating bacterial species comprising Escherichia coliand their strains, preferably enterohemorrhagic E. colipathogen of type 0104, in blood, preferably whole...
DE102011105809A1 Determining effect of plants on room climate, preferably on relative humidity in rooms and buildings, comprises recording room climate values e.g. temperature, and setting values in relation to plant physiological factors and parameters  
Determining the effect of plants on the room climate, preferably on the relative humidity in rooms and buildings, comprises recording room climate values e.g. temperature, humidity, air exchange...
DE102012003700B3 Process for the separation of associations of malignant cells and stromal cells associations from a Malignomgewebeprobe  
In the method, a Malignomgewebeprobe is purified ex vivo, crushed, suspended in culture medium, subjected to a treatment with collagenase and the Kollagenaseaufschlu├čprodukt is zentrifiugiert. The...