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DE212017000061U1 Composition for detecting a single-stranded target RNA  
A composition for detecting a single-stranded target RNA in an acellular sample comprising a plurality of RNAs, comprising: (i) a C2c2-guideRNA that hybridizes to the single-stranded target RNA;...
DE212017000062U1 Use for detecting a single-stranded target RNA  
Use of: (i) a C2c2-guideRNA that hybridizes to a single-stranded target RNA; (ii) a labeled detection RNA; and (iii) a C2c2 protein, splits the RNA present in a sample, wherein the C2c2 protein...
DE212017000056U1 Kits for detecting a target RNA in a sample  
A kit for detecting a target RNA in a sample comprising a plurality of RNAs, the kit comprising: (a) a labeled detection RNA; and (b) a C2c2 protein and / or a nucleic acid encoding the C2c2...
DE102011006459B4 Process for the enzymatic synthesis of aromatic aldehydes or ketones  
A process for the enzymatic synthesis of aromatic aldehydes or ketones from mono- or bicyclic aromatic epoxides, which synthesis is enzyme-catalyzed in a cell-free reaction mixture and wherein the...
DE102013101617B4 Agent for the selection and / or production of barley resistant to yellow mosaic virus  
An isolated nucleic acid or a fragment thereof, wherein the nucleic acid has the nucleotide sequence of SEQ ID NO: 1 or SEQ ID NO: 5, or a nucleotide sequence homologous to the nucleotide sequence...
DE102015201531A1 Method of changing the specificity of a cobalamin-dependent 2-Hydroxyisobutryl-CoA mutase  
The present invention relates to a method for the targeted modification of the specificity of cobalamin-dependent 2-hydroxyisobutyryl CoA Mutases that occur in different strains of bacteria, and...
DE102014203964A1 Granules containing isomaltulose synthase  
The invention relates to a granulate containing A) at least one enzyme selected from at least one of the groups selected from the transferases EC 2, hydrolases the EC 3, EC 4 and the lyases...
DE102012216904A1 A process for the isomerization of (R) -3-hydroxycarboxylic acids to 2-hydroxy-2-methyl carboxylic acids  
The present invention relates to a process for the enzymatic isomerization of (R) -3-hydroxy carboxylic acids to give the corresponding 2-hydroxy-2-methyl carboxylic acids. The conversion is...
DE112012001017T5 Plants having enhanced yield-related traits and processes for their preparation  
The present invention relates generally to the field of molecular biology and concerns a method for enhancing various economically important yield-related traits in plants. More specifically, the...
DE102011006459A1 Preparing an aryl aldehyde/ketone from a cyclic aryl epoxide, useful e.g. as a flavoring agent, where process takes place in a cell-free reaction mixture comprising styrene-oxide isomerase in an aqueous solution and the aryl epoxide  
Enzymatic synthesis of aryl aldehyde (I) or aryl ketone (II) from mono- or bi-cyclic aryl epoxide, is claimed, where the enzymatic catalyzed synthesis takes place in a cell-free reaction mixture...
DE102009060935A1 Sucrosemutase with improved product specificity  
For the biotechnological production of isomaltulose and isomaltulose-containing compositions of sucrose, the invention provides an improved means, particularly a Sucrosemutase with improved...
DE102009046623A1 Using a homologous to a MEAB protein protein for increasing the enzymatic activity of a 3-hydroxy-CoA mutase  
The invention also provides the use of a homologous to a MeAB protein protein for increasing the enzymatic activity of a 3-hydroxy-CoA mutase, a fusion protein comprising a 3-hydroxy-CoA mutase...
DE102008031350B4 A prokaryotic xylose isomerase for the construction of xylose-fermenting yeasts  
The present invention relates to the use of nucleic acid molecules, which encode a bacterial xylose isomerase (XI) which are preferably derived from Clostridium phytofermentans, for the...
DE102004062386B4 Monacolin K biosynthesis genes  
An isolated DNA molecule comprising a polynucleotide which it is mkA and which has a nucleotide sequence of SEQ ID NO: 2, wherein said polynucleotide encodes a polypeptide having an activity...
DE102008031350A1 A prokaryotic xylose isomerase for the construction of xylose-fermenting yeasts  
The present invention relates to the use of nucleic acid molecules, which encode a bacterial xylose isomerase (XI) which are preferably derived from Clostridium phytofermentans, the implementation...
DE102007028441A1 Targeted delivery of recombinase activity by trans-splicing  
The Invention relates to nucleic acid transcripts that only by a trans-splicing event a Nukleinsäuretranskript provide, for a polypeptide with recombinase activity encoding, and for such nucleic...
DE102007023986A1 Protein with uridine diphosphate (UDP)-glucose 4,6-dehydratase, UDP-4-keto-6-deoxyglucose 3,5-epimerase and UDP-4-ketorhamnose 4-ketoreductase activity useful for converting UDP-glucose to UDP-rhamnose  
Protein with uridine diphosphate (UDP)-glucose 4,6-dehydratase, UDP-4-keto-6-deoxyglucose 3,5-epimerase and UDP-4-ketorhamnose 4-ketoreductase activity is new. Protein with uridine diphosphate...
DE102006017760A1 Enzymatic preparation of 2-hydroxy-2-methylcarboxylic acid comprises producing 3-hydroxycarboxylic acid in aqueous reaction solution, incubating the obtained solution and converting to 2-hydroxy-2-methylcarboxylic acid  
Enzymatic preparation of 2-hydroxy-2-methylcarboxylic acid from 3-hydroxycarboxylic acid, comprises producing 3-hydroxycarboxylic acid in an aqueous reaction solution containing...
DE102005025191A1 A method for identifying fungicidally active compounds based on isopentenyl pyrophosphate isomerases  
The This invention relates to a method for identifying Fungicides, the use of fungal IPP isomerase for identifying of fungicides and the use of inhibitors of IPP isomerase as fungicides.
DE10154254B4 sealing arrangement  
sealing arrangement at a connection between a wheel hub (11) in a wheel bearing (16) is held and on the adjacent said bearing inner ring (18) of the wheel bearing (16) is a flanged sleeve (26)...
DE10101962B4 DNA sequence with regulatory regions for expression of proteins  
DNA containing the nucleotide sequence of SEQ ID NO: 1 or a sequence that the at least 352 nucleotides to 1112 of SEQ ID NO: 1, and is active as a promoter, the open reading frame for the enzyme...
DE102004062386A1 Monacolin K biosynthesis genes  
Of the Monascus produced cholesterol inhibitor monacolin K is a secondary Metabolite from the group of polyketides. The invention provides probes prepared that are specific for the gene cluster of...
DE10047286B4 Isomalt producing transgenic plant  
Transgenic Plant which in at least one of their cells in the plant educated sucrose and isomaltulose from the isomaltulose formed 6-O-α-D-glucopyranosyl-D-sorbitol (1,6-GPS) and / or...
DE102004022065A1 Screening procedures for hydantoin racemases  
The present invention relates to a method for screening and hydantoin racemases new hydantoin racemases they nucleic acid sequences encoding and a method for mutagenesis.Hydantoin racemases are...
DE10006462B4 Production of non-cariogenic sugar in transgenic plants  
Recombinant Nucleic acid molecule which a) regulatory sequences of an active in plant cells promoter; b) operatively linked thereto a DNA sequence encoding a protein with the enzymatic activity a...
DE10309580A1 Identifying inhibitors of type II isopentenyl: dimethylallyl isomerase  
The invention provides a protein crystal of the protein type II isopentenyl: dimethylallyl isomerase ready. The invention further provides the crystal structure of the protein in the absence and...
DE10308850A1 Preparation of conjugated polyunsaturated fatty acids, useful in nutrition, cosmetics and pharmaceuticals, comprises expressing specific isomerases in eukaryotic, particularly plant, cells  
Preparation of conjugated polyunsaturated fatty acids (I), having at least two double bonds, in transgenic eukaryotic organisms comprises expressing a specific nucleic acid (II) in an organism...
DE20023437U1 Hydantoin racemase  
Rec hydantoin racemase, characterized in that it is derived from Arthrobacter aurescens DSM 3747th
DE10229978A1 Preparation of conjugated polyunsaturated fatty acids, useful in nutrition, cosmetics and pharmaceuticals, comprises expressing specific isomerases in eukaryotic, particularly plant, cells  
Preparation of conjugated polyunsaturated fatty acids (I), having at least two double bonds, in transgenic eukaryotic organisms comprises expressing a specific nucleic acid (II) in an organism...
DE10327937A1 Use of cyclophilin D or creatine kinase for inhibiting apoptosis, useful for treating e.g. cardiac infarct and in drug screening, also use of their inhibitors for treating tumors  
Use of cyclophilin D (I) and/or creatine kinase (II), or their biologically active fragments or derivatives; nucleic acids that encode them, and their activators (collectively (A)), for inhibiting...
DE10224249A1 New di-2-((4-acetamido- and -amino-2-nitrophenyl)amino)-ethyl disulfide and known dye thiol and disulfide compounds are used with enzyme of protein disulfide isomerase type in cosmetic for treating keratinous fibers, especially human hair  
Di-2-((4-acetamido-2-nitrophenyl)amino)-ethyl disulfide (IV) and di-2-((4-amino-2-nitrophenyl)amino)-ethyl disulfide (V) are new. Di-2-((4-acetamido-2-nitrophenyl)amino)-ethyl disulfide of formula...
DE10224248A1 New di-2-((4-acetamido- and -amino-2-nitrophenyl)amino)-ethyl disulfide and known dye thiol and disulfide compounds are used with enzyme of protein disulfide isomerase type in cosmetic for treating keratinous fibers, especially human hair  
Di-2-((4-acetamido-2-nitrophenyl)amino)-ethyl disulfide (IV) and di-2-((4-amino-2-nitrophenyl)amino)-ethyl disulfide (V) are new. Di-2-((4-acetamido-2-nitrophenyl)amino)-ethyl disulfide of formula...
DE10220574A1 Process for the preparation of amino acids with coryneform bacteria using phosphoglucose isomerases from coryneform bacteria  
The invention relates to proteins with phosphoglucose isomerase activity from coryneform bacteria, coryneform bacteria containing these proteins, and to processes for producing L-amino acids, in...
DE10214406A1 Preparation of recombinant protists, useful for preparation of recombinant proteins, by transforming auxotrophic mutant with DNA that complements the auxotrophy  
Preparing of recombinant protists (A) comprising preparing an auxotrophic protist mutant, transforming it with recombinant DNA (I) containing at least one gene that complements the auxotrophy and...
DE10203352A1 Process for the preparation of 7-dehydrocholesterol and / or its biosynthetic intermediates and / or secondary products in transgenic organisms  
The invention relates to a method for the production of 7-dehydrocholesterol and/or the biosynthetic intermediate or subsequent products thereof by the cultivation of organisms, in particular,...
DE10160066A1 Amidase from Variovorax  
The present invention is to provide a novel amidase from the organism Variovorax paradoxus. The invention also deals with the nucleic acids encoding this enzyme as well as the vehicles containing...
DE10154245A1 Genes encoding regulatory proteins  
The invention relates to novel nucleic acid molecules, their use for the construction of genetically improved microorganisms and processes for the preparation of fine chemicals, in particular...
DE10139062A1 Process for the fermentative production of L-amino acids using coryneform bacteria  
The invention relates to a process for the preparation of L-amino acids, in which the following steps are carried out: DOLLAR A a) fermentation of the desired L-amino acid-producing coryneform...
DE10101962A1 DNA sequence with regulatory regions for expression of proteins  
The invention relates to a DNA sequence comprising the triosephosphate isomerase gene including its regulatory sequences, to a DNA sequence, which is an active promoter, to expression and...
DE10064454A1 Preparing fine chemicals, particularly Vitamins E and K, useful as antioxidants e.g. in foods or medicine, by growing organisms with altered shikimate biosynthesis pathway  
Preparation of fine chemicals (I) by culturing organisms in which the shikimate pathway (SP) has been altered relative to the wild type. Independent claims are also included for the following: (a)...
DE10154254A1 Elastic bush seal for automotive hub to wheel bearing zone  
A rubber seal surrounds the zone between an automotive wheel hub and bearing. The seal is an elastic bush (13) one end of which rests against the outer surface (47) of a cylinder extension (29),...
DE10050124A1 Using the acetylamino from Amycolatopsis orientalis racemization of carbamoyl  
The present invention is directed to the use of the N-acetylamino acid racemase from Amycolatopsis orientalis subspecies lurida for racemizing N-carbamoyl amino acids. DOLLAR A This use allows the...
DE10047865A1 New encoding the deaD gene nucleotide  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence selected from the group DOLLAR A a) polynucleotide which is at least 70% identical to a polynucleotide...
DE10133668A1 For The Board gene coding nucleotide sequences  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence selected from the group DOLLAR A a) polynucleotide which is at least 70% identical to a polynucleotide...
DE10047864A1 New encoding the lees gene nucleotide  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a...
DE10047286A1 Isomalt producing transgenic plant  
The invention relates to a transgenic plant, which can produce isomaltulose, to a transgenic plant, which can produce 6-O- alpha -D-glucopyranosyl-D-sorbitol, to a transgenic plant, which can...
DE10042535A1 A method for improving the production and isolation of trans-dihydroxycyclohexadiene carboxylic acids and / or their derivatives, and a thereto suitable genetically modified organism  
The invention relates to the production of genetically-modified, non-pathogenic organisms and a method for the improved preparation and isolation of trans-dihydroxycyclohexadiene carboxylic acids...
DE10037612A1 New phosphopentose isomerase gene from Coryneform bacteria, useful for transforming cells for improved fermentative production of L-amino acids, especially lysine  
Isolated polynucleotide (I) from Coryneform bacteria contains a sequence that is at least 70% identical with a sequence encoding a 157 amino acid (aa) polypeptide (II), encodes a polypeptide at...
DE10037611A1 New ribulose-phosphate 3-epimerase gene from coryneform bacteria, useful for transforming cells for improved fermentative production of L-amino acids, especially lysine  
An isolated polynucleotide (I) from coryneform bacteria containing a sequence that: (a) is at least 70% identical to a sequence encoding a 219 amino acid (aa) polypeptide (II); (b) encodes a...
DE10030647A1 Preparing fine chemicals, particularly Vitamins E and K, useful as antioxidants e.g. in foods or medicine, by growing organisms with altered shikimate biosynthesis pathway  
Preparation of fine chemicals (I) by culturing organisms in which the shikimate pathway (SP) has been altered relative to the wild type. Independent claims are also included for the following: (a)...
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