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DE102018107224A1 Peptides and combinations of peptides of non-canonical origin for use in immunotherapy against various cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic procedures. In particular, the present invention relates to the immunotherapy of cancer....
DE102017219800A1 Peptide carrier materials as biofunctionalized collectors  
The invention relates to a method for the selective separation of submicro or microparticles by means of a biofunctionalized collector, a biofunctionalized collector comprising at least one...
DE102010017130B4 Hybrid-Verbindung, deren Verwendung und Verfahren zu deren Herstellung  
Hybrid-Verbindung der Formel A-B wobeiA ein Aminopyrazol oder ein Derivat davon ist undB ein Peptid undA und B unmittelbar oder mittels eines Linkers kovalent miteinander verbunden sinddadurch...
DE112011100556B4 Low hemolytic antimicrobial peptide, its pharmaceutical composition and use  
An antimicrobial peptide having an amino acid sequence according to the following formula:(P1)M(A1X1X2)N(P2)Xwhere P1 is selected from the group consisting of basic amino acids; where A1 is...
DE102016208110A1 Method and support material for providing metal ion-binding molecules for the recovery and recovery of valuable metals  
The invention relates to a method for providing metal ion-binding molecules based on the phage display method by means of a planar carrier material with immobilized metal ions. The invention...
DE112011105133T5 Octapeptide for the preparation of radiopharmaceutical agents, that produced on the basis of pharmaceuticals and diagnostics of somatostatin receptor-expressing tumors  
The invention belongs to octapeptides, which are derivatives of octreotide, as well as to the estimates based on radiopharmaceutical agents which are used in the Tumorer identifier, ie, for field...
DE102009055015B4 Yeast secretion system based on a signal sequence of the hydrophobin 1 gene sequence of Trichoderma reesei  
Use of a peptide having an amino acid sequence according to one of the sequences of SEQ ID No. 1 to 13 or a functional variant thereof having a sequence identity of at least 80%, preferably at...
DE112011100556T5 Gering hemolytic antimimikrobielles peptide whose pharmaceutical composition and use  
It is an antimicrobial peptide disclosed which represented an amino acid sequence of the formula as (P1)M(A1X1X2)N(P2)X , wherein P1 is selected from the group consisting of basic amino acids...
DE112009003659T5 Means of getting rid of a multidrug resistance Mitel  
The invention belongs to medicine, namely to pharmacology, and could be used to overcome multidrug resistance in cancer and infectious patients undergoing long-term chemotherapy. Essence of the...
DE10113776B4 An isolated streptavidinbindendes competitively elutable peptide, this complete fusion peptide, nucleic acid coding therefor, expression vector, to methods for producing a recombinant fusion protein, and methods for the detection and / or for the recovery of the fusion protein  
An isolated streptavidinbindendes competitively elutable peptide comprising at least two streptavidinbindende individual modules, wherein the distance between the two individual modules is 0 and a...
DE19735587B4 Peptide having radioprotective effect, this containing cosmetic or pharmaceutical composition for nucleic acid encoding, manufacturing processes for this peptide and use as radioprotektives agent  
Peptide having radioprotective effect, the sequence of SEQ ID No .: 2: Cys Ala Leu Val Tyr Pro Ala Gln Cys, or the sequence SEQ ID NO. 3:Ala Leu Ser Tyr Pro Ala Gln having.
DE10344561B4 Using a tetra, penta and octapeptide of royal jelly  
Use of the tetrapeptide NEVN, the pentapeptide NEVNF and the octapeptide NEVN NEVN to achieve antimicrobial effects in human and veterinary medicine.
DE102009055015A1 Yeast secretion system based on a signal sequence of the hydrophobin 1 gene sequence of Trichoderma reesei  
The present invention relates to a yeast secretion system, based on a signal sequence from the hydrophobin 1 protein from Trichoderma reesei, which mediates the secretion of recombinant proteins...
DE10311106B4 Peptides to cold intolerance inducing autoantibodies, nucleic acids coding therefor, their use and pharmaceutical compositions comprising  
An isolated nucleic acid molecule selected from the group comprising: a) a nucleic acid molecule comprising, consisting of the following amino acid sequences of a nucleotide sequence coding for a...
DE102005041616B4 Melanoma-associated MHC class I-associated oligopeptides and coding for these polynucleotides and their uses  
Melanoma specific immunogen, which consists of a peptide with a length of 9-15 residues and comprises an amino acid sequence selected from SEQ ID Nos. 2, 3 and 6 to 11.
DE102009034779A1 Synthetic analogues of bacterial lipopeptides and their use for the therapy and prophylaxis of allergic diseases  
The present invention relates to novel, of a spore germination protein of the species Bacillus cereus-derived Lipopepitide with immunostimulatory activity, processes for the preparation of...
DE102006059294B4 Methylation inhibitor of a eukaryotic nucleic acid methylation reaction, the use of which, inhibition process and determination method of inhibition  
Methylation inhibitor for a eukaryotic nucleic acid methylation reaction, wherein said methylation inhibitor is a peptide having a length of up to 17 amino acids comprising a chain of amino acid...
DE102009012640A1 With a Phosphoamidatgruppe modified compound, and their use  
The present invention relates to a modified compound, characterized by at least one chemoselective built phosphoramidate group of the general formula (I)NPO (OR1) (OR1'),where R1 and R1' is...
DE102008060549A1 Active peptide construct for extracellular enrichment  
The present invention relates to a drug-peptide construct for extracellular enrichment, a method for the enrichment of active ingredients in an extracellular compartment of a multicellular object,...
DE20122915U1 Peptidomimetics as protease inhibitors  
Compound of the formula 1 in which: - R0 a bond or difluoromethylene and - R1 Hydrogen, an optionally substituted aliphatic group, an optionally substituted cyclic group or an optionally...
DE10154458B4 Peptides for analysis of gluten in foodstuffs and other mixtures of substances and their use  
Peptides MHNHPRF, SHFTTRS, QPIPQLW, NLPRLYE, WHASWLL.
DE102007059924A1 Allele and isotype-specific intervention in associated with autoimmune diseases MHC class II molecules by peptides  
The present invention relates to a peptide for the treatment or prophylaxis of an autoimmune disease, a gene coding for this peptide nucleic acid molecule, a pharmaceutical composition comprising...
DE10163130B4 Apoptotic active peptides and pharmaceutical compositions comprising  
apoptotic selected active peptide from the group consisting of: and their pharmaceutically acceptable salts thereof.
DE4042752B4 Process for the preparation of microparticles containing an active agent in a biodegradable polymeric carrier,  
process for the preparation of microparticles comprising an agent in a biodegradable, biocompatible polymeric carrier included with a) the polymeric carrier material in a suitable Solvent, in...
DE4021517B4 Formulations with delayed release of water-soluble peptides  
formulation with slowed release of octreotide or Nα- [Α-glucosyl- (1-4-deoxyfructosyl)] - or Nα- [Β-deoxyfructosyl] -DPhe-Cys-Phe-DTrp-Lys-Thr-Cys-Thr-ol in free form, Salt form or in the form of...
DE10208877B4 Using a streptavidin binding peptide  
use a streptavidin binding peptide comprising an amino acid sequence according to SEQ ID 1-6 to one produced in a protein biosynthesis system purification defined protein, a protein defined for...
DE10149678A1 New peptide compounds containing upto 6 aminoacid residues, are potent and specific thrombin inhibitors used for treating and diagnosing diseases associated with thrombin  
Peptide compounds (I), containing upto 6 aminoacid residues, are new. Peptide compounds of formula Y 1>-(NH-X 1>-CO)-(NH-X 2>-CO)-(NH-X 3>-CO)-(NH-X 4>-CO)-(NH-X 5>-CO)-(NH-X 6>-CO)-Y 2>(I), their...
DE112007001030T5 Amyloid-ß fibrillogenesis-inhibiting peptide  
On Peptide having 8 to 30 amino acid residues comprising an amino acid sequence, represented by the following formula (I) is represented: X1Asp-X2-X3-X4-Pro-X5-X6 (I)wherein X1 an amino acid with...
DE102007002386A1 Pharmaceutically active compounds  
The present invention relates to pharmaceutically active compounds from an isoflavone or isoflavone glycoside and covalently with this connected, an amino acid, a peptide or peptide derivative...
DE102006059294A1 Methylation inhibitor for eukaryotic nucleic acids comprises a peptide with a sequence of up to 17 amino amino acids, including a defined sequence  
Methylation inhibitor for eukaryotic nucleic acids comprises a peptide (I) with a sequence of up to 17 amino amino acids, including a defined sequence. Methylation inhibitor for eukaryotic nucleic...
DE602004007105T2 COMPOSITION FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS  
The present invention features compositions and related methods for treating IBS and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional...
DE102006035899A1 New polysaccharide-peptide-conjugate, where the peptide portion contains a sequence having a signal group that is splittable by thrombin at its carbon-terminal end, useful in a procedure for determining the thrombin generation in a sample  
Polysaccharide-peptide-conjugate with a molecular weight of more than 10 kDa, where the peptide portion contains a sequence having a signal group that is splittable by thrombin at its...
DE102006035577A1 A radiopaque conjugate  
The This invention relates to a radiopaque conjugate the Use of the conjugate for the preparation of a diagnostic and therapeutic composition, a pharmaceutical and / or diagnostic A composition...
DE69133552C5 Deoxyribonucleic acid sequence encoding non-A, non-B hepatitis virus - obtd. Hutch C59 subgroup encoding polypeptide(s), useful as vaccines, and immuno reactive ABS for diagnosis of virus  
Sequence (I) comprises (a) the Hutch c59 DNA sequence shown in SEQ ID NO:46 of the spec; (b) degenerate sequences of the sequence of (a); (c) a mutant variant of the NANBV Hutch c59 strain with...
DE19933492B4 A conjugate for placement of a cell, or membrane compartment-specific transport of active substances, a process for its preparation and its use  
conjugate the presentation of a cell-, compartment-specific or membrane Transport, wherein the conjugate is in the order given the following components: - A penetratin having the following...
DE102006015140A1 Heterocycles with activity against neurodegenerative diseases  
It Compounds of formula I are described with n = 0-2, in the X, Y, Z represent either a nitrogen or carbon atom, in the latter case R3-5 the meaning of H or an alkyl group having 1-4 carbon atoms,...
DE102005059242A1 Molecular markers for tumor diagnosis and therapy  
The This invention relates to the diagnosis, prognosis, monitoring and therapy of neoplastic diseases such as tumor diseases, in particular Cancers of the endometrium and their metastases.
DE19930177B4 Intermolecularly associating compounds and their use  
connection of the general formula (I) X (B)m (I)in which X an m-valent moiety and for CH4-m; NH3-m; N+H4-m; > P- (when m = 3); > P+<(When m = 4); > B- (when m = 3); a linear atomic group C2H6-m; >...
DE4237113B4 Peptides and their fusion proteins, expression vector and methods for producing a fusion protein  
Peptide; comprising the amino acid sequence Trp-X-His-Pro-Gln-Phe-YZ, wherein X represents any amino acid and Y and Z either both Y or Gly Glu Arg or Lys and Z mean and their fusion proteins,...
DE19917195B4 Peptide to induce an immune response against tumor cells containing this pharmzeutische compositions, uses thereof, nucleic acid coding therefor and these nucleic acid expression vector containing  
Peptide, characterized in that it comprises the sequence according to SEQ ID No .: 1: Ser Thr Ala Pro Pro Val His Asn Val has.
DE102005009099A1 New camptothecin-peptide derivatives, useful for treating cancer  
Campothecin-peptide derivatives (I) are new. Campothecin-peptide derivatives of formula (I) are new. R 1hydrogen or hydroxy; R 2hydrogen, amino, nitro or N,N-dimethylaminomethyl; R 3hydrogen or...
DE102005009084A1 New anthracyclin-peptide derivatives, useful for treating cancer, especially of the prostate, are cleaved, in the tumor, by prostate-specific antigen to release active antitumor agent and are transported by serum albumen  
Anthracyclin-peptide derivatives (I) are new. Anthracyclin-peptide derivatives of formula (I) are new. R 1hydrogen, hydroxy or methoxy; R 2hydrogen or hydroxy; m : 0-5; n : 0-6; Pep. : peptide...
DE19911771B4 LHRH antagonist, process for its preparation and its use  
LHRH Antagonist having the formula Ac-D-Nal (2)1D-Cpa2-D-Pal (3)3-Ser4-N-Me-Tyr5D-Hci6-Nle7-Arg8th-Per9D-Ala10NH2and its Salts with pharmaceutically acceptable acids.
DE4007605B4 SDK peptides, process for their preparation and therapeutic compositions containing them  
peptides having the general formula H2N - W - Ser - Asp - Lys - X - OH wherein X is a Pro or Lys residue or a valence bond, and W represents a Thr or Pro residue, or a valence bond, with the...
DE10344561A1 Use of proteins and peptides from royal jelly, as antibacterial, fungicidal and antiviral agents, where activity is associated with short amino acid sequences  
Use of the antibacterial, fungicidal and/or antiviral activities of proteins and peptides (A) of royal jelly, where activity is correlated with the presence of short amino acid sequences (X). (X)...
DE102004026135A1 An MHC molecules binding tumor associated peptides  
The Invention relates to a tumor-associated peptide with an amino acid sequence the selected is selected from the group consisting of SEQ ID NO. 1 to SEQ ID NO. 577 of the attached sequence...
DE10005932B4 Peptides and their use in a method for the diagnosis of celiac disease and dermatitis herpetiformis  
Hexapeptide with the sequences QPQQPF QPEQPF, NPEQPF, QPENPF, NPENPF QPDQPF, NPDQPF, QPDNPF, NPDNPF QQQPFP QEQPFP, NEQPFP, QENPFP, NENPFP QDQPFP, NDQPFP, QDNPFP, NDNPFP EEQPFP, DDQPFP, DEQPFP,...
DE102004011503A1 Identifying and quantifying tumor-associated peptides by chemically identically modifying peptides to generate different physical characteristics, useful for treating tumorous and/or adenomatous diseases  
Identifying and quantifying tumor-associated peptides comprises chemically identically modifying peptides from samples in order to generate different physical characteristics in the peptides from...
DE10360435A1 New antibiotic peptides, useful in treating or preventing a microbial or viral infections or in inactivating Gram-positive and -negative bacteria, protozoa, fungi and virus  
Peptides (I) are new. Peptides of formula (A1-X1-A2)n (I) are new. A1 or A2Arg, Lys, Val or Ile; X1Trp, Phe or Pro; and n : 2 or 3. ACTIVITY : Antibacterial; Protozoacide; Fungicide; Virucide. No...
DE10358824A1 Antibacterial macrocycles with substituted biphenyl  
The Invention relates to antibacterial macrocycles with substituted Biphenyl, and processes for their preparation, their use for Treatment and / or prophylaxis of diseases and their use for the...

Matches 1 - 50 out of 275 1 2 3 4 5 6 >