Matches 1 - 32 out of 32


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DE102008062567A1 Dipeptoid prodrugs and their use  
The present application relates to dipeptide similar prodrug derivatives of Processes for their preparation, their use for the treatment and / or prophylaxis of diseases and their use for...
DE102009035593A1 New tetrapeptide derivatives are proprotein convertase inhibitors, useful to treat e.g. viral or bacterial diseases, diabetes, arteriosclerosis, cancer, Alzheimer's disease, obesity, and respiratory tract disease  
Tetrapeptide derivatives (I) are new. Tetrapeptide derivatives of formula (P5-P4-P3-P2-P1) (I) are new. P1 : arginine mimetic; P2-P4 : amino and/or imino acid radical; and P5 : N-terminal...
DE102007002386A1 Pharmaceutically active compounds  
The present invention relates to pharmaceutically active compounds from an isoflavone or isoflavone glycoside and covalently with this connected, an amino acid, a peptide or peptide derivative...
DE102006052755A1 New peptide derivatives and peptidomimetics are transglutaminase inhibitors useful for the treatment or prophylaxis of e.g. celiac disease, fibrosis, thrombosis, neurodegenerative disorders, Huntington's chorea and Parkinson disease  
Peptide derivatives and peptidomimetic (D) and their stereoisomer forms, E/Z-isomers, enantiomers, enantiomeric mixture, diastereomers, diastereomeric mixture, racemates, tautomers, anomers,...
DE102006035899A1 New polysaccharide-peptide-conjugate, where the peptide portion contains a sequence having a signal group that is splittable by thrombin at its carbon-terminal end, useful in a procedure for determining the thrombin generation in a sample  
Polysaccharide-peptide-conjugate with a molecular weight of more than 10 kDa, where the peptide portion contains a sequence having a signal group that is splittable by thrombin at its...
DE19930177B4 Intermolecularly associating compounds and their use  
connection of the general formula (I) X (B)m (I)in which X an m-valent moiety and for CH4-m; NH3-m; N+H4-m; > P- (when m = 3); > P+<(When m = 4); > B- (when m = 3); a linear atomic group C2H6-m; >...
DE102004063339A1 Probe for detecting nucleic acids  
The Invention relates to a probe for detecting nucleic acids, method for the preparation of the probe, methods of making a detection reactions and test kits that contain those reagents necessary...
DE102004008042A1 Process for the preparation of amino acid esters and their acid-addition salts  
object The invention provides a process for the preparation of amino acid esters and / or their acid addition salts of monomeric or polymeric amino acids, peptides, proteins, and Alcohols, which...
DE19737245B4 Fibrous Mikrotubus from a Oligoglycinverbindung and methods for making the fibrous Mikrotubus  
Fibrous Mikrotubus with a tubular body and a number in this tubular body contained spherical vesicles, each of said tubular body and each of these vesicles is a lipid of the formula: Mo...
DE10251894A1 New peptide-containing benzophenoxazine or napthoquinone derivatives, useful as chromogenic substrates for enzymes, e.g. for diagnosis, monitoring therapy and detecting pyrogens  
Peptide-containing benzo(a)phenoxazine and naphthoquinone derivatives (I) - (IV) are new. Peptide-containing benzo(a)phenoxazine and naphthoquinone derivatives of formulae (I) - (IV) are new. R =...
DE10239832A1 New sarcolysine derivatives, e.g. amide or peptide compounds, useful as anticancer agents with reduced toxicity to healthy cells  
Sarcolysine derivatives (I) (e.g. N-substituted and/or amide or peptide derivatives) are new. Sarcolysine derivatives of formula (I) and their salts are new. R1, R2 = H, substituted benzoyl,...
DE10226921A1 Antibacterial amide macrocycles  
The present invention relates to compounds of general formula (I), to processes for their preparation, to pharmaceutical compositions comprising them and to their use in the treatment of diseases...
DE10146737A1 Coniosulfides and their derivatives, process for their preparation and use as medicines  
The invention relates to compounds of formula (I), which are formed from the micro-organism Coniochaeta ellipsoidea Udagawa, DSM 13856, or from one of its mutations and/or variants during...
DE10157882A1 A process for the preparation of carboxamides  
The invention relates to a method for the production of carboxylic acid amides, especially peptides, from an acid component in the form of a compound having at least one carboxy group and an amine...
DE10105041A1 Tripeptides and tripeptide derivatives for the treatment of neurodegenerative diseases  
The invention relates to the use of specific tripeptides for the treatment of neurodegenerative diseases, and to pharmaceutical compositions comprising the tripeptides. The tripeptide derivatives...
DE10064398A1 New 1,2-diphenyl-3-(3-hydroxy-3-phenylpropyl)-azetidin-2-one derivatives, useful for treating lipid metabolism disorders, e.g. hyperlipidemia, hypercholesterolemia, arteriosclerosis or insulin resistance  
1,2-Diphenyl-3-(3-hydroxy-3-phenylpropyl)-azetidin-2-one derivatives (I) are new. Azetidinones of formula (I) and their salts are new. R1 - R6 = -Q-L, H, halo, CF3, NO2, COOH, COOT, CONH2, CONHT',...
DE10046934A1 A process for the fermentative production of non-proteinogenic L-amino acids  
A process for preparing non-proteinogenic L-amino acids by direct fermentation of a known strain of microorganism having a deregulated cysteine ‚Äč‚Äčmetabolism in manner known per se, characterized...
DE19930177A1 Intermolecular associating compounds and this comprehensive aggregates  
The invention relates to a compound of the general formula (I) X(B)m, wherein X is a unit of the value m and the members B are the same or different and represent K-R, wherein K represents a bond...
DE19828114A1 Prodrugs unstable inhibitors of dipeptidyl peptidase IV  
The present invention relates to new, specific and effective prodrug compounds of the general formula ABC in which A is any amino acid, B is the chemical bond between A and C or any amino acid...
DE19715103A1 Metallocene-amino acid and peptide complexes  
The invention relates to novel metallocene amino acid and peptide complexes containing a metallo-organic compound of formula (I): [A-(LaM)-B-C-D-E-F-G-H-I-J]<+> [N]<->, wherein L is independent,...
DE19737245A1 New oligo-glycine peptide-lipid compounds  
Oligo-glycine compounds of formula MO-(COCH2NH)pCO(CH2)nCO(NHCH2CO)qOM (I) are new. M = H or alkali metal; n = 6-18; p and q = 1 or more, provided that p+q = 6 or less. Also claimed is a fibrous...
DE19632772A1 New benzamidines  
Disclosed are compounds having formula (I) wherein the radicals R, R<1>, R<2>, R<3>, R<4>, R<5> and R<6>, as well as l, m, and n have the meaning indicated in the description, and the production...
DE19544212A1 New LH-RH antagonists having improved activity  
New LH-RH antagonists are disclosed, in particular peptidomimetics and peptides modified in a side chain, their salts with pharmaceutically acceptable acids and a process for preparing these LH-RH...
DE4444893A1 Peptides and synthetic membranes  
The invention concerns linear peptides of formula (I) R-A-B-C-D-E-OH, wherein R, A, B, C, D and E have the meanings indicated; the production of said linear peptides; and their use as biosensors,...
DE4436772A1 New dipeptide derivative, process for its preparation and pharmaceutical compositions containing this compound  
Compounds of formula (I) in which R<1> and R<2> are hydroxy or an acyloxy group and R<3> is hydrogen, where R<2> and R<3> together may also signify a valency line. Process for their production...
DE4423724A1 Kinetically controlled process for the enzymatic production of peptides  
The invention pertains to a kinetically controlled process for enzymatic production of fully protected peptides formula (III): X-NH-A<1>-CO-NH-A<2>-CO-Y, wherein fully protected amino acid esters...
DE4404002A1 New thiazolyl-peptide derivs.  
Macrocyclic thiazolylpeptides (I) and their salts are new: A = a gp. of formula (a), (b) or (c); R<1> = 1-8C alkoxy; R<2> = 1-6C alkoxy; R<3> = R<2> or a gp. of formula (d).
DE4038947A1 DITHIOLANO- AND DITHIANOGLYCIN CONTAINING RENININHIBITORISCHE PEPTIDES, METHOD FOR THEIR PRODUCTION AND THEIR USE IN DRUGS  
Dithiolano- and dithianoglycin-containing renin-inhibiting peptides having general formula (I), are disclosed, in which A, B, D, E, R<1>, R<2>, R<3>, n, X and Y have the meaning given in the...
DE4038921A1 RENININHIBITORISCHE PEPTIDES FROM CYCLOHEXYLSTATIN TYPE, PROCESS FOR THEIR PRODUCTION AND THEIR USE IN DRUGS  
Renin-inhibiting peptides of the cyclohexylstatin type having general formula (I), in which A, B, D, E, Y, R<1>, R<2> and n have the meanings given in the description, are disclosed, as well as a...
DE4030350A1 New retro:virus protease-inhibiting oligopeptide derivs. - for treatment of retro-viral infection e.g. AIDS  
Peptides of formula (I) and their salts are new, where Y = O, S, CHR5''R6'' or NR7, l = 0-1. A = D-(E)n-(F)o-(G)p-, A' = D'-(E')n'-(F')o'-(G')p'-, E,E',F,F',G,G' = natural or other amino acid,...
DE3827252A1 Process and apparatus for the continuous separation of mixtures containing biological microsystems and cells  
The invention relates to a process and an apparatus for the continuous separation of mixtures of biological materials suspended in a fluid medium. Some of these materials are ferromagnetic or...
DE3839401A1 N-HETEROCYCLIC ALCOHOL DERIVATIVES  
Compounds of the formula are disclosed. These compounds are inhibitors of renin and therefore useful as cardiovascular agents. The symbols have the following definitions: R1 is a fully saturated,...

Matches 1 - 32 out of 32