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DE10065650A1 A method for calculating chemically self-reproducing systems  
The present invention relates to a method for calculating chemical self-replicating systems. In order to provide a corresponding method by which biological reproduction processes in detail are...
DE10059144A1 Modulating transcription of pro-inflammatory gene products  
The present invention relates to inhibitors of the transcription factor IRF-1, their use as therapeutic agents and their use for the prevention or therapy of chronic (transplant arteriosclerosis...
DE10064353A1 Oligonucleotide chip, useful for determining gene expression patterns, contains probes selected for specificity with regions of open reading frame  
Oligonucleotide chip (OC) has many probe positions (PP) each of which contains many identical probe molecules that together form a probe. Each probe sequence differs from sequences at all other...
DE10063986A1 Plants with improved resistance  
The invention relates to transgenic plants with improved resistance to pathogens, whereby the improved resistance is a result of an increased expression of one or more nucleic acid sequences...
DE10061338A1 Diagnosis of angiogenesis-associated diseases  
The invention relates to chemically modified genomic sequences of genes associated with angiogenesis, to oligonucleotides that are directed against the sequence and/or to PNA oligomers for...
DE10004102A1 Nucleic acids differentially expressed between tumor and normal cells, useful for diagnosis or therapy of tumors and for screening active agents  
A nucleic acid (I) with differential expression between tumor and normal cells comprising: (i) one of 550 fully defined sequences 250 nucleotides as given in the specification; (ii) fragments of...
DE10057841A1 A method for the detection of protozoa of the genus Naegleria  
The invention relates to a method for rapidly and specifically detecting protozoae of the genus Naegleria and especially of the genus Naegleria fowleri. The invention further relates to specific...
DE10055285A1 New marker for the diagnosis and therapy of tumors  
The present invention relates to novel markers for tumors, preferably CTCL. The present invention further relates to their use for the diagnosis or treatment of tumor diseases, preferably CTCL.
DE10054974A1 Diagnosis of diseases associated with Cdk4  
The present invention relates to chemically modified genomic sequence of the Cdk4 gene directed against the sequence of oligonucleotides and / or PNA-oligomers for detecting the cytosine...
DE10054972A1 Diagnosis of diseases associated with humic  
The present invention relates to chemically modified genomic sequence of the gene humos directed against the sequence of oligonucleotides and / or PNA-oligomers for detecting the cytosine...
DE10057415A1 Production of omega dihalo and bromohydrin substituted quinone derivatives useful as intermediates and for bonding to nucleic acid oligomers  
Omega-dihalo and -bromohydrin substituted quinone derivatives (I) are produced by reaction of a quinone derivative with a halogenating agent in a solvent system comprising water, polar solvent and...
DE10125089A1 New polynucleotide representing mtrA and B genes of coryneform bacteria, useful, when suppressed, for increasing fermentative production of amino acids  
Isolated polynucleotide (I) from coryneform bacteria is at least 70% identical with a sequence (i) that encodes a 226 amino acid (aa) polypeptide (2), or 503 aa polypeptide (3), reproduced. (I)...
DE10054934A1 Isocyanates with amino groups  
The invention relates to novel isocyanates with tert. Amino groups, a process for their preparation, and their use for synthesis and modification of polymers. DOLLAR A subject of the invention are...
DE10053821A1 Detection of rare Candida species  
The invention relates to a nucleic acid molecule, to a kit containing said nucleic acid molecule, to the use of said nucleic acid molecule for detecting fungi or for sequence determination of...
DE10145585A1 coding for genes and hemD hemB nucleotide  
The invention relates to an isolated polynucleotide containing a polynucleotide sequence, selected from the group a) polynucleotide that is at least 70 % identical with a polynucleotide encoding a...
DE10051628A1 Means for inactivation of pathogenic microorganisms and the use thereof  
The invention relates to an agent which inactivates pathogens and to the use thereof. Said agent contains an element that bonds with the nucleic acids of the pathogens and a conjugate, which...
DE10049549A1 Inhibitor of the transcription factor IFR-1, useful for treating e.g. transplant rejection and autoimmune disease, reduces expression of CD40  
An inhibitor (I) of the expression and/or activity of the transcription factor (IRF-1; interferon regulatory factor) as a therapeutic agent, is new. Independent claims are also included for the...
DE10051542A1 Fluid for transporting or rinsing organs, e.g. kidneys, for transplantation, containing antisense oligonucleotide to reduce expression of transplant damaging materials  
A new organ transport and rinsing fluid (A) contains an antisense oligonucleotide (I) (optionally incorporated in a vector), to reduce the expression of materials causing damage to transplants.
DE10113958A1 New codes for the gene nucleotide mikE17  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence selected from the group DOLLAR A a) polynucleotide which is at least 70% identical to a polynucleotide...
DE10049902A1 Biochip accelerating macromolecule immobilization electrically, for detection or recognition, has electrically-conductive polymer coated onto electrodes  
A solid support (1) has sensor locations comprising electrode- and immobilization surfaces. A controller applies electrical signals to the electrodes independently. Electrically-conductive polymer...
DE10049074A1 A method for selecting high affinity to a target nucleic acids binding  
The invention relates to a method for selecting nucleic acids that bond with high affinity to a target from a mixture of nucleic acids. The method comprises the following steps: a) loading the...
DE10049010A1 Transferrin-polycation / DNA complexes for the systemic treatment of tumors with cytotoxic proteins  
The invention relates to a DNA complex containing at least one DNA molecule and coding for at least one therapeutically effective protein having cytotoxic activity; and a transferrin-conjugated...
DE10048633A1 Method for in vitro diagnosis of endometriosis  
The invention relates to a method for the diagnosis of endometriosis, wherein the amount of gene product of at least one gene selected from the group consisting of fibronectin, insulin-like growth...
DE10047865A1 New encoding the deaD gene nucleotide  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence selected from the group DOLLAR A a) polynucleotide which is at least 70% identical to a polynucleotide...
DE10133668A1 For The Board gene coding nucleotide sequences  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence selected from the group DOLLAR A a) polynucleotide which is at least 70% identical to a polynucleotide...
DE10132724A1 For dctA gene coding nucleotide sequences  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence selected from the group DOLLAR A a) polynucleotide which is at least 70% identical to a polynucleotide...
DE10123070A1 New codes for the gene nucleotide atr43  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence selected from the group DOLLAR A a) polynucleotide which is at least 70% identical to a polynucleotide...
DE10113957A1 New codes for the def gene nucleotide  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence selected from the group DOLLAR A a) polynucleotide which is at least 70% identical to a polynucleotide...
DE10048893A1 New nucleic acids involved in neuronal regeneration, useful in screening for modulators of regeneration or synaptic efficiency, and potential therapeutic agents  
Nucleic acid (A), involved in regenerative neuronal processes, is any of 48 sequences fully defined in the specification. Independent claims are also included for the following: (a) nucleic acid...
DE10048214A1 Plants with masked fertility  
The invention relates to transgenic plants with masked fertility, said masked fertility being induced by a modified expression of the nucleic acid sequence of SEQ ID NO:2 or a homologue thereof,...
DE10048009A1 A method for the detection of fungal infections  
The invention relates to a method for detecting clinically relevant fungal infections. A multiplex amplification reaction is carried out using DNA that has been isolated from patient material in...
DE10047866A1 New codes for the gene nucleotide dep67  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of: a) polynucleotide which is identical to the extent of at least 70 % to...
DE10047864A1 New encoding the lees gene nucleotide  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a...
DE10047404A1 New codes for the msiK gene nucleotide  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a...
DE10047403A1 New codes for the gene nucleotide pPGK  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70 % to...
DE10046625A1 New codes for the gene nucleotide ndkA  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence selected from the group DOLLAR A a) polynucleotide which is at least 70% identical to a polynucleotide...
DE10045579A1 New codes for the gene nucleotide atr61  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence selected from the group DOLLAR A a) polynucleotide which is at least 70% identical to a polynucleotide...
DE10120095A1 New codes for the gene nucleotide PknB  
The invention relates to the protein kinase B of C. glutamicum and a fermentation process for the preparation of L-amino acids using corynebacteria in which at least the pknB gene is amplified,...
DE10120094A1 New codes for the pknD gene nucleotide  
The invention relates to an isolated polynucleotide which contains a polynucleotide sequence selected from the group comprising: a) a polynucleotide which is at least 70% identical to a...
DE10112098A1 New encoding the CHRA gene nucleotide  
The invention relates to nucleotidic sequences from corynebacteria which code for the transcription regulator chrA, a process for the fermentative preparation of L-amino acids using coryneform...
DE10046623A1 New dps gene of coryneform bacteria, useful when overexpressed, for increasing fermentative production of L-amino acids, encodes a DNA-protection protein  
Isolated polynucleotide (I) from coryneform bacteria that represents the dps gene is: (i) 70% identical with a polynucleotide that encodes a 165 amino acid sequence (S2), reproduced; (ii) encodes...
DE10046400A1 Neuronal expressed protein and its use  
The invention relates to novel, specifically expressed proteins, nucleic acid sequences, recombinant nucleic acid structures containing said nucleic acid sequences, and vectors containing the...
DE10046318A1 Detecting tumor cells from presence of specific stem-loop DNA molecules outside the nucleus, useful for diagnosis and monitoring of tumors  
Detecting tumor cells (A) by detecting, outside the nucleus, a DNA (I) that consists of a single strand but has a double-stranded (ds) (stem-loop) structure. The ds stem comprises at least 4 bp;...
DE10045497A1 New codes for the ppsA gene nucleotide  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a...
DE10045496A1 New codes for the ptsI gene nucleotide  
The invention relates to the phosphotransferase system enzyme I of C. glutamicum and a process for the fermentative preparation of L-amino acids using coryneform bacteria in which at least the...
DE10043369A1 Procedures and functional particles for carrying out chemical or biological reactions or syntheses  
The invention relates to a method and functional particles for carrying out chemical or biological reactions or syntheses. The aim of the invention is to provide a solution ensuring complete...
DE10136987A1 For the CLPC gene coding nucleotide sequences  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a...
DE10136986A1 New cysD, N, K, E and H genes from coryneform bacteria, useful, when over expressed, for increasing fermentative production of L-amino acids  
Isolated polynucleotides (I) from coryneform bacteria containing a sequence that represents at least one of the cysD, N, K, E or H genes, are new. Isolated polynucleotides (I) from coryneform...
DE10112430A1 New codes for the gene nucleotide dep33  
The invention provides nucleotidic sequences from corynebacteria which code for the efflux protein Dep33, a process for the fermentative preparation of L-amino acids using coryneform bacteria in...
DE10044681A1 New L-lactate dehydrogenase gene from coryneform bacteria, useful, when overexpressed, for increasing fermentative production of L-amino acid  
Isolated polynucleotide (I) from coryneform bacteria containing a lld2 gene at least 70 % identical with a sequence that encodes a 420 residue amino acid sequence (2), given in the specification,...