Match Document Document Title
DE10002446A1 Gene chip for a newborn screening  
The invention relates to a nucleotide support containing a selection of oligonucleotide sequences for detecting reference sequences which are relevant for at least two phenotypes, or their...
DE10004147A1 Oligonucleotides for the amplification and qualitative and quantitative detection of bacterial 16S rRNA useful to determine bacterial contamination of foodstuffs, waters, and in clinical microbiology  
An oligonucleotide for the amplification and qualitative and quantitative detection of RNA sequences derived from 16S rRNA genes or gene fragments, is new. An oligonucleotide for the amplification...
DE10003631A1 New nucleoside derivatives with photolabile protecting groups, useful in oligonucleotide synthesis, particularly on solid phases, e.g. for hybridization testing  
New nucleoside derivatives (I) with photolabile protecting groups. Nucleoside derivatives of formula (I) are new: [Image] R 1>-R 4>and R 7>H, NO 2, CN, halo, 1-4C alkyl, alkoxy or alkoxyalkoxy,...
DE10003580A1 Method, kit and DNA probes for the detection of fungal species in clinical material  
The invention relates to a method and a kit for detecting a fungal species in clinical material. Oligonucleotides of the sequence protocol are used as DNA probes for detecting DNA segments of...
DE19960206A1 Complexation of RNA with polyethylenimines for their stabilization and cellular infiltration  
The invention relates to complexes of a ribonucleic acid (RNA) and polyethyleneimine (PEI), to processes for their preparation and their use for protecting RNA from enzymatic and non-enzymatic...
DE10001101A1 New codes for the ptsH gene nucleotide  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence selected from the group DOLLAR A a) polynucleotide which is at least 70% identical to a polynucleotide...
DE19963126A1 A process for the preparation of 6-O-alpha-D-glucopyranosyl-D-sorbitol  
The invention relates to a method for enzymatically producing 6-0- alpha -D-glucopyranosyl-D-sorbite (1,6-GPS) from isomaltulose. According to the invention, the isomaltulose is provided in an...
DE19962893A1 Parallel sequencing of nucleic acids in a mixture, useful e.g. for detecting mutations, comprises a series of single-base extension reactions using protected, labeled nucleotides  
Parallel sequencing of at least two different nucleic acids (I) and (II) in a mixture. Parallel sequencing of at least two different nucleic acids (I) and (II) in a mixture, involves a surface...
DE19962577A1 same chromatographic material and method using  
The invention relates to a chromatography material for separating nucleic acid mixtures by means of a carrier and ion exchanger functions applied thereto. The carrier comprises a fibrous material....
DE19962803A1 Method and apparatus for maskless production of biopolymers  
The invention relates to a method and a device for the light-controlled synthesis of biopolymers on surfaces. Patterns of individual sequences (20) are produced on the surfaces by representing an...
DE10036175A1 Determining activity of nucleic acid, useful for optimizing therapeutic or diagnostic nucleic acids, by transforming organisms, in parallel, with many different sequences  
Determining the biological activity of nucleic acid sequences (I) by: (i) inserting, in parallel, many expression vectors, each containing a test (I) linked to control sequences, into many...
DE19958042A1 Surface-modified carrier materials for binding of biological materials, to processes for their preparation and their use  
The invention relates to surface modified supporting materials for binding biological materials, in addition to a method for the production and the use thereof in the isolation and purification of...
DE19957827A1 Oligomer array with PNA and / or DNA oligomers on a surface  
The invention relates to an oligomer array with PNA (Peptide Nucleic Acid) and/or DNA oligomers on a surface, said oligomers comprising oligomers of 6 to 20 monomers or nucleobases each. Said...
DE19959582A1 Nucleic acids coding for new acetylcholine receptor beta subunits of insect  
The invention relates to nucleic acids coding for acetylcholine receptor beta subunit of insects, as well as polypeptides which exert the biological function of such acetylcholine receptor beta...
DE19959328A1 New codes for the zwa1 gene nucleotide  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence selected from the group DOLLAR A a) polynucleotide which is at least 70% identical to a polynucleotide...
DE10005808A1 Preparation of template DNA from processed plant-based foods, for detecting genetically modified material in soya products, comprises purification of a crude extract  
Preparation of a template DNA (I) from a processed plant food (A) comprises extraction a crude DNA fraction and subjecting this to fractionation by poly(ethylene glycol) (PEG) precipitation and/or...
DE10024717A1 Method and apparatus for preparing oligomers and arrays of oligomers as well as the use of the device  
The invention relates to a method and an apparatus for preparing oligomers and arrays of oligomers, wherein the synthesis process is extended by an additional neutralization step. This is a...
DE19956686A1 New codes for genes sucC and sucD nucleotide  
The invention relates to the genes sucC and sucD encoding polynucleotides comprise the polynucleotide sequences selected from the group DOLLAR A a) polynucleotide which is identical to at least...
DE19955303A1 Test microorganisms  
The present invention relates to a novel approach for directly identifying germs in sample material. According to the inventive method and the question formulated, a selected probe group is used...
DE10056747A1 New nucleic acid sequences from a human immune deficiency virus intersubtype, useful for treatment, prevention and diagnosis of infection  
Polynucleotide (I) is (i) one of the sequences (1; 9087 bp), (2; 4288 bp) or (3; 2605 bp) fully defined in the specification, or their fragments or derivatives, or (ii) a sequence that hybridizes...
DE10051726A1 Intermediate for oligonucleotide synthesis comprises partially hydrolysed cross-linked vinyl acetate copolymer loaded with nucleotide derivative  
A chemical product comprising a partially hydrolysed cross-linked vinyl acetate copolymer carrier material loaded with nucleotide derivative(s) is new.
DE19952113A1 Nucleoside derivatives having photolabile protecting groups  
The invention relates to nucleoside derivatives with photolabile protecting groups of general formula (I), where R<1> = H, F, Cl, Br, I, NO2; R<2> = H, CN, where R<1> and R<2> are not...
DE19951824A1 New N-terminal fragment of insulin-like growth factor binding protein-3 and its complexes with growth factors for treatment and diagnosis of e.g. muscular atrophy  
Peptide N-IGFBP-3 (the N-terminal fragment of insulin-like growth factor binding protein-3) (I), or its biologically active fragments, analogs and/or derivatives, or synthetic peptides and...
DE19950409A1 New codes for the pck gene nucleotide  
An isolated polynucleotide from coryneform bacteria containing a polynucleotide sequence selected from the group DOLLAR A a) polynucleotide which is identical to at least 70% with a polynucleotide...
DE19947792A1 New codes for the gene nucleotide Irp-  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence selected from the group DOLLAR A a) polynucleotide which is at least 70% identical to a polynucleotide...
DE19947791A1 New codes for the eno gene nucleotide  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence selected from the group DOLLAR A a) polynucleotide which is mindestes to 70% identical to a polynucleotide...
DE19946597A1 Stabilized Guanidinlthiocyanat and its use  
The invention relates to stabilized guanidine thiocyanate that contains 5 to 5000 ppm, based on the weight of the guanidine thiocyanate, of thiourea and/or N-acetylcysteine. Due to its excellent...
DE19945964A1 Methods and nucleic acids for the detection of microorganisms relevant brewery  
The invention relates to a method for determining the presence of micro-organisms specific to the brewing process, in addition to nucleic acids and combinations thereof which can be used in said...
DE19945916A1 Nucleic acid molecules for the detection of bacteria and phylogenetic units of bacteria  
The present invention relates to nucleic acid molecules which allow the identification of bacteria or bacteria groups. The region containing 23S/5S rRNA and pertaining to the bacterial genome is...
DE19945398A1 Electrochemical detection of sequence-specific nucleic acid oligomer hybridization events  
The present invention relates to a method for electrochemically detecting sequence-specific nucleic acid-oligomer hybridisation events. DNA-/RNA-/PNA oligomer single strands which are bound to a...
DE19943374A1 Mechanism for attaching nucleic acids to a solid phase  
The invention relates to a method for binding nucleic acids to a solid phase during which a solution containing a nucleic acid is brought into contact with a solid phase, which has hydrophobic and...
DE19951715C1 New 18-fluoro-labeled cytosine derivatives, useful as tracers for monitoring activity of transferred cytosine deaminase genes in gene therapy of tumors  
18-Fluorine-labeled cytosine derivatives (I) are new. 18-Fluorine-labeled cytosine derivatives of formula (I) are new. R1, R2 = H or F, or R1 is H or CH3 and R2 is fluoromethyl, 2-fluoroethyl or...
DE19943587A1 New codes for the dapF gene nucleotide  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence selected from the group DOLLAR A a) polynucleotide which is at least 70% identical to a polynucleotide...
DE19925073A1 Nucleic acid molecules with specific detection of native PrP · S · · · c, production and use  
It describes a method for isolating nucleic acid molecules that are capable of specific interaction with native PrPSc and to distinguish them from native PrP c and native PrPSc capable by: DOLLAR...
DE10044468A1 New nucleic acid encoding delta-6-desaturase, useful for producing ciliates and plants that overproduce unsaturated fatty acids, derived from Tetrahymena  
New nucleic acid (I) is a 1219 base pair (bp) sequence (i) or fragments of at least 8 nucleotides and encodes a DELTA -6-desaturase from Tetrahymena with a 352 amino acid (aa) sequence (ii) or its...
DE10014639A1 cDNSen with a coding of enzymes for fructan synthesis with a low-temperature expression as well as methods for their isolation  
It is derived from wheat sucrose: fructan 6-fructosyl transferase cDNA provided which is characterized in that it comprises a nucleotide sequence encoding an as SEQ.ID No. corresponds to 1 in FIG....
DE19935433A1 A microfluidic reaction support  
The present invention is a microfluidic reaction support, which enables a purely fluidic, or a light-controlled synthesis and analysis of oligomers or polymers.
DE10016073A1 Covalent immobilization of biopolymers, useful for studying e.g. gene expression, by coupling amino group on biopolymer to reactive group on substrate  
Covalent immobilization of biopolymers (I) on a solid phase having, on at least part of its surface, amino reactive groups (halo, aldehyde, epoxy, iso(thio)cyanate), by reacting the surface with...
DE19939578A1 New nucleic acid encoding hemocyanin, useful for gene therapy of tumors and for recombinant production of fusion proteins for vaccination  
Nucleic acid (I) containing a sequence that encodes hemocyanin (II), a domain of (I) or its fragment with the immunological properties of at least one domain of (II), are new. Nucleic acid (I) is:...
DE19938092A1 Nucleoside derivatives and methods for their preparation  
Disclosed are novel nucleoside derivatives of general formula (I), wherein R1 represents a nucleobase or a nucleobase that is provided with at least one protective group, R2 means an H atom or a...
DE19937837A1 New human gene OLFXX, encoding an olfactory receptor, useful for diagnosis, treatment and development of pharmaceuticals  
The human OLFXX gene (I), having a 4.5 kbase sequence, fully defined in the specification, is new. Independent claims are also included for the following: (1) transcription factors, RNA...
DE19937846A1 New human gene BOCT, encoding an organic cation transporter, useful for diagnosis, treatment and development of pharmaceuticals  
The human BOCT gene (I), having a 5700 base pair sequence, including 5' and 3'-untranslated regions, fully defined in the specification, is new. Independent claims are also included for the...
DE19937839A1 New human gene OLFXY, encoding an olfactory receptor, useful for diagnosis, treatment and development of pharmaceuticals  
The human OLFXY gene (I), having a 3600 base pair sequence, fully defined in the specification, is new. Independent claims are also included for the following: (1) transcription factors, RNA...
DE19937607A1 Laboratory robot, useful for automated isolation of nucleic acid, includes orientation device to ensure proper alignment between robotic arm and unit being transported  
Laboratory robot having at least one robotic arm, movable within a predetermined working region, on which is a gripping device for grasping at least one functional unit (FU) to be moved by the...
DE19905913C1 Stabilizing double-stranded nucleic acid, useful e.g. in restoring double strands after sterilization, by incubation with histone-like protein from Thermotoga maritima  
Stabilizing double-stranded (ds) nucleic acid (I) by incubating it with a non-specifically or specifically binding HU (histone-like) protein (II), comprising a 90 residue amino acid sequence,...
DE19935303A1 Oligonucleotides for inhibiting the expression of human Eg5  
The invention relates to an oligonucleotide or one of its derivatives that is characterized by a sequence that corresponds to a nucleotide sequence that encodes a defined part of human eg5 or a...
DE19935302A1 Conjugates and methods for their preparation and their use for transporting molecules across biological membranes  
The invention relates to conjugates, methods for their production, and to the use of these conjugates for transporting low molecular weight compounds and macromolecules via biological membranes,...
DE19935967A1 New DNA encoding Arabidopsis thaliana 1-deoxy-D-xylulose-5-phosphate reductoisomerase for identifying modulators of the enzyme that can be used as herbicides, antibiotic or anti-malarial agents  
A DNA (I) which encodes Arabidopsis 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXPR) or its functional fragment, is new. Independent claims are also included for the following: (1) a DNA...
DE19935204A1 Labelling and masking of incomplete products in the production of polymeric compounds, especially oligonucleotides, comprises the addition of reactive functional compounds during the synthesis  
Bi- to oligo-functional compounds are added during the synthesis of optionally mixed polymers with a pre-determined sequence to mask and label incomplete products formed and to facilitate their...
DE19935088A1 DNA sequences that are suitable for the specific detection of Pseudomonas putida KT2440  
The invention relates to DNA sequences which are suited for specifically detecting Pseudomonas putida KT2440.