Matches 1 - 33 out of 33


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DE202017002052U1 Nucleoside pearl necklaces sequencing  
An apparatus for DNA sequencing by passing a single-stranded DNA or RNA strand with anhybridized, chemically modified (nucleo-) bases, nucleosides or nucleotides by a biological or non-biological...
DE102012110740A1 Preparing carbohydrate-analogs from five- or six-membered ring glycals, comprises reacting glycal by addition of ketene to corresponding cycloketone, converting cycloketonic to ketoxime, and converting ketoxime in lactam by rearrangement  
Preparing carbohydrate-analogs from five- or six-membered ring glycals, comprises: (a) reacting the glycal by the addition of ketene to the corresponding cycloketone; (b) converting cycloketonic...
DE69314239C5 Process for Stereoselektivglycosylierung  
A process for the synthesis of a β-anomer enriched nucleoside of the formula which, if appropriate in a suitable solvent, performing a nucleophilic SN2-substituting a sulfonyloxy group (Y) of an...
DE102008050273A1 Apparatus and method for synthesizing a biopolymer and method for recovering a reagent for synthesizing a biopolymer  
A Apparatus for synthesizing a biopolymer has a reaction chamber (100), an outlet (410b) connected to the reaction chamber (100) is connected, a plurality of recovery tanks (461A, 461C, 461g,...
DE202005021489U1 A composition as for the synthesis of compounds phosphitylated  
Composition, containing a compound capable of forming enolates, and a phosphoramidite.
DE102004019098A1 Caging Groups  
The This invention relates to novel nucleoside derivatives of the general Formula I, where R1 equal H, halogen, NO2, CN, OCH3. an alkyl, alkoxy or alkoxyalkyl group having 1 to 4 carbon atoms,...
DE10105077A1 Hybrid-protecting group  
The invention relates to photo-labile hybrid protecting groups and the application thereof in the synthesis of protected synthons for the light-controlled synthesis of biopolymers, in particular...
DE19837387A1 New nucleic acid analogs useful in therapeutic or diagnostic agents or electronic components, consist of 3'-deoxypentopyranosyl nucleosides  
Nucleic acid analogs (I) consisting of 3'-deoxypentopyranosyl nucleosides are new. Nucleic acid analogs (I) consisting of 3'-deoxypentopyranosyl nucleosides of formula (Ia) or (Ib) are new: R<1>,...
DE19827777A1 New nikkomycin antibiotics with antifungal, fungicidal, miticidal and insecticidal activity produced by recombinant microorganisms  
Nikkomycins Lz, Lx, Lj and Li are new. Nikkomycins of formula (I) are new: R1 = a group of formula (i) or (ii): R2 = OH or NHCH(COOH)CH2CH2COOH. An Independent claim is also included for...
DE19838506A1 The indole derivatives and their use for the treatment of malignant and other diseases based on pathological cell proliferations  
The invention relates to tyrosine kinase inhibitors of bis-indolyl compounds of formula (I), to the medicaments containing said inhibitors and to their use in treating malignant and other diseases...
DE19815901A1 A process for preparing pentopyranosylnucleosides  
The invention relates to a method for the production of a pentopyranosyl nucleoside 3', 4'-cyclic acetal, whereby a pentopyranosyl nucleoside is made to react with an aldehyde, ketone, acetal or...
DE19812162A1 Nucleotidaktivierte di- and oligosaccharides, as well as processes for their preparation I  
The invention relates to a method for the production of nucleotide activated disaccharides and oligosaccharides with n saccharide units, whereby a nucleoside diphosphate sugar (NDP sugar) is...
DE19741738A1 Linker nucleoside(s) containing alkenyloxy or phthalimido-alkyl groups  
Linker nucleosides of formula (I)-(IV) are new: R1 = H, OH or halogen (preferably Br or Cl); R2-R4 = 2-12C alkenyloxy or phthalimido(1-12C)alkyl, where phthalimido is optionally substituted by 1-4...
DE19741715A1 New pentopyranosyl nucleoside compounds  
Pentopyranosyl nucleosides of formula (I) and (II) are new. : R1 = H, OH or halogen; R2-R4 = H, NR5R6, OR7, SR8, oxo, 1-12C alkyl or (CnH2n)R10R11; n = 1-12; R10, R11 = H or 1-12C alkyl, or...
DE19703031A1 Process for the preparation of NDP-sugar  
The invention relates to a method for the production of nucleoside-diphosphate sugar (NDP-sugar), in which one sugar-1-phosphate reacts with a nucleoside-triphosophate in the presence of a...
DE19640054A1 Di:nucleotide(s) with modified base, sugar and phosphate groups  
Dinucleotides with modified base, sugar and phosphate groups of formula (I) are new. R1, R6 = NH2, N3, OMe, allyl, OH, H or F; R2, R5 = O or NH; provided that when R5 is NH then R2 is not NH; and...
DE19637042A1 Heterocyclic compounds and their use in the detection of nucleic acids  
The present invention pertains to compounds of general formula (I), where R1 to R7 have the notations given in the application, as well as preparation thereof. Compounds can be used as substrates...
DE19620170A1 Nucleoside derivatives having photolabile protecting groups  
The invention relates to nucleoside derivatives with photo-unstable protective groups of the general formula (I) in which R<1> is H, NO2, CN, OCH3, halogen, alkyl or alkoxyalkyl with 1 to 4 C...
DE19537334A1 New piperidine carboxylic acid and pyrrolidine carboxylic acid derivs.  
Piperidine and pyrrolidine derivs. of formula (I) are new. Z = pyranoside, pyranosyl residue bound via. the 6-position, alkyl pyranoside bound via the 6-position, furanoside, furanosyl residue...
DE19512484A1 Carbohydrate-modified cytostatics  
The invention relates to cytostatics which are made tumour-specific by modification with sugar. Suitable spacers ensure serum-stability and intracellular effect at the same time.
DE4444996A1 Nucleoside derivatives having photolabile protecting groups  
The invention concerns nucleoside derivatives with photolabile protective groups of general formula (I), in which R<1> is H, NO2, CN, OCH3, halogen or alkyl or alkoxyalkyl with 1 to 4 carbon...
DE4418691A1 3 '- (4'-) non-radioactively labeled nucleosides and nucleotides with aminocarboxylic acid, peptide or carboxylic acid-spacer  
Disclosed are 3'-(4'-) modified nucleosides and nucleotides of general formula (1), wherein R' is hydrogen, mono-, di- or triphosphate, alkyl phosphonate, dialkyl phosphinate or phosphoramidite; X...
DE4418690A1 Nucleoside 5'-mono-phosphate ester(s) of glyceryl di:ether derivs.  
Nucleoside 5'-monophosphate esters of glyceryl diether derivs. of formula (I), their salts, tautomers, optically active forms, and racemic mixts., are new: R1 = 1-20C satd. or unsatd. alkyl chain,...
DE4418842A1 Colourless, thermostable, non-toxic cyclised oligo- or poly:saccharide use as charge controller or enhancer  
The use of cyclised oligo- or polysaccharides (I) with 3-100 monomeric saccharide units as charge controllers and charge enhancers for electrophotographic toners and developers, in...
DE4207363A1 Antiviral nucleoside analogs, PRODUCTION AND PHARMACEUTICAL USE  
New and known nucleoside analogues particularly effective against hepatitis B and HIV infections are disclosed, as well as their production and use.
DE4140463A1 2'-deoxy-isoguanosine WHOSE isosteres ANALOG AND USE THEREOF  
2'-desoxy-isoguanosine, isoster analogues and isoguanosine derivates having the formulas (I) to (V) are disclosed, as well as a process for preparing the same from compounds having the general...
DE4037363A1 New 2-O-alkyl nucleotide(s) and polymers contg. them - for nuclease-resistant anti-sense probes and to treat viral infection including herpes influenza and AIDS and cancer  
Nucleotide analogues of formula (I) are new. In (I) B = nucleobase; A = O or CH2; C = OR. R = alkyl, alkenyl or alkynyl comprising at least 2C atoms (especially allyl). D and E = reactive groups...
DE4005969A1 NEW trisubstituted pyrroles, METHOD FOR THE PRODUCTION AND MEDICAMENTS CONTAINING THESE COMPOUNDS  
Compounds of the formula (I) in which the substituents R<1> - R<6> have the significance set out in the claims, process for their production and medicaments containing these compounds for the...
DE3928900A1 New psoralen-modified nucleotide derivatives - used as anti-sense nucleotide(s) in the treatment of viral infections, e.g. AIDS  
Cpds. of formula (I) are mew. where B = a gp. of formula (1), (2), or (3), X4, X5 = independently H or a protecting gp, or X4 and X5 together form = CR1-NR2. n, m = 0 or 1. H1 = NH, NR2, O or S,...
DE3924424A1 NUCLEOSIDE DERIVATIVES, PROCESS FOR THEIR PRODUCTION, THEIR USE AS DRUGS AND THEIR USE IN THE nucleic SEQUENCING  
Derivatives of nucleosides and nucleotides, process for their manufacture, and use of said nucleoside derivatives as medicaments and their use in the sequencing of nucleic acids. The invention...
DE3606395A1 Nucleic acid building blocks, process for their preparation and their use  
2'-Deoxyribonucleosides whose 5'-OH group is protected by a base-labile group, and use of these 2'-deoxyribonucleosides for preparing oligodeoxyribonucleotides.
DE3606394A1 Ribonucleosides, process for their preparation and their use  
Ribonucleosides whose 2'-OH group is blocked by a beta -activated alkylsulphonyl group, process for their preparation and use of these ribonucleosides for preparing oligoribonucleotides.
DE3531102A1 Epiminopyranosides, process for their preparation, and their use  
3,4-Dideoxy-3,4-epiminopyranosides are described, in which the free hydroxy group is in the 2-position in the trans-position to the epimino group, and 2,3-dideoxy-2,3-epiminopyranosides in which...

Matches 1 - 33 out of 33