Match Document Document Title
DE102015219651A1 Compositions containing sugar amine and fatty acid  
Compositions comprising a) one or more sugar amines of the formula (I) Wherein R1 and R2 are independently H, CH3 Or 2-hydroxyethyl and / or one or more corresponding protonated sugar amines with...
DE202008018643U1 Nucleosidphosphoramidat prodrugs  
A compound according to the following formula: Wherein (a) R1 Is hydrogen, methyl, ethyl, n-propyl, i-propyl or a substituted or unsubstituted phenyl, the substituent of the substituted phenyl...
DE102015011780A1 New glutaminyl cyclase inhibitors  
The invention relates to a compound of formula (I) for use as a glutaminyl cyclase inhibitor, a compound-containing composition for use as a QC inhibitor, and methods of preparation.
DE102015214603A1 Phosphorhaltige Aminoglycosid-Salze  
Aufgabe ist es, Aminoglycosid-Verbindungen bereitzustellen, die eine retardierende Aminoglycosid-Freisetzung über klinisch relevante Zeiträume in therapeutisch wirksamen Konzentrationen...
DE102015009439B4 Triple Target HIV-1 NAT for the detection of all known genotypes  
A primer / probeset for the detection of HIV, in particular HIV-1, comprising at least one primer / probeset 1 consisting of oligonucleotides comprising SEQ ID NOs 1, 2 and 3; Primer / probeset 2...
DE112012003470B4 Process for the preparation of 2- [4 - [(methylamino) carbonyl] -1-H-pyrazol-1-yl] adenosine monohydrate  
Process for the preparation of 2- [4 - [(methylamino) carbonyl] -1-H-pyrazol-1-yl] adenosine monohydrate of the formula I Comprising the following steps: a) reacting 2-...
DE102015219343A1 A process for preparing galactose derived from marine algae using agarase  
A method for preparing galactose by means of an enzymatic treatment of a red algal residue is provided. The process for preparing galactose comprises: preparing a residue; Treating the residue...
DE102015008536A1 Discontinuous oligonucleotide ligands  
The present invention relates to an oligonucleotide conjugate K of the structure Or a pharmaceutically active salt thereof wherein RNA1, RNA2, RNA3, and RNA4 are each strands of a ribonucleic acid...
DE112015001085T5 Antibodies, uses and procedures  
The present invention relates to anti-human OX40L antibodies, new medical uses and methods.
DE102015216558A1 PROCEDURE AND TEST KIT FOR FAST ISOLATION OF NUCLEIC ACIDS BY SMOKE SURFACES  
The invention relates to a method for isolating nucleic acids from nucleic acid-containing samples, characterized in that free nucleic acids released by lysis are bound to a solid phase with a...
DE102014018527A1 CYCLO - nucleosides  
The present invention relates to Cyclo-nucleosides of formula (I) R is hydrogen, alkyl or acyl, R1 is hydrogen or alkyl, X is hydrogen or the group OR, and Y is oxygen or NH.
DE102015008631A1 Medicines for cancer therapy  
The present invention relates to novel chemical compounds, in particular benzophenone derivatives which are suitable as active ingredients in the drug treatment of cancer.
DE202014010612U1 Double Run cassette  
Cassette (1) for synthesizing a plurality of batches of a [18F] -labelled positron emission tomography (PET) -Tracers, said cartridge comprising: (i) an anion exchange column (3, 4) for each of...
DE19858588B4 The dye-labeled oligonucleotide for labeling a nucleic acid molecule  
The dye-labeled oligonucleotide for labeling a a target sequence section comprising a nucleic acid molecule, wherein the dye-labeled oligonucleotide comprises the following components: a) - a loop...
DE102014013397A1 Perlenketten sequencing  
There will be described using labeled nucleotides, a method for sequencing nucleic acids. Firstly, the nucleotides on the ribose or deoxyribose may be labeled and be integrated by means of a...
DE102014112055A1 Di- and triphosphate prodrugs  
The invention relates to prodrugs as useful compounds, in particular Nukleosiddi- triphosphate and prodrugs, and a method for preparing these compounds. Object of the present invention is to...
DE102014210662A1 Device and method for obtaining and glycoglycerolipids glycosphingolipids from lipoid phase  
The present invention relates to an apparatus and method for conserving and hydrolysefreien separating glycoglycerolipids and of glycoglycerolipids and glycosphingolipids from a lipoid phase which...
DE102014208194A1 Purification of epidaunorubicin  
The present invention relates to a method for the purification of epidaunorubicin, in particular the separation of the impurity epi-Feudomycin as it occurs as a by-product of the biotechnological...
DE102014001464A1 RNAi technology  
Ribonucleic acids (RNAs) can be blocked by small inhibitory RNAs. In this way, genes off. This mechanism known as RNA interference was first described by Andrew Fire and Craig Mello. For the...
DE112013004650T5 Multiplexpyrosequenzierung using nichtinterferierender, noise-terminating Polynukleotididentifikationstags  
The present disclosure relates generally to a multiplexing method for analyzing samples, comprising the Polynukleotidamplifikation to production of amplified products, wherein one or more target...
DE102013111487A1 The bispecific antibody fragment and pharmaceutical combination preparation with such a  
The invention relates to a bispecific antibody fragment (10) with a first detection point (12) and at least a second detection point (14), which specifically recognize each at least one structure...
DE102013105144A1 The pharmaceutical combination product with an anti-idiotype antibody fragment  
The invention relates to a pharmaceutical combination preparation (10), in particular to suppression of an immune response, preferably a humoral immune response against a therapeutic organism...
DE112004000265B4 Novel photolabile protecting groups for improved methods for the preparation of oligonucleotide arrays  
Use of a compound having the general formula (1): in which R1 COOY, wherein Y is selected from the group consisting of an optionally substituted alkyl group having up to 10 carbon atoms with the...
DE102013006487A1 Iterative assembly and disassembly of predetermined, artificial DNA constructs and the specific exchange of functional genetic elements  
Versatile Assemblierungsverfahren for DNA constructs of higher order for the integration of molecular function have been described and patented. no uniform concepts found in the practical work of...
DE102013006487A9 Iterative assembly and disassembly of predetermined, artificial DNA constructs and the specific exchange of functional genetic elements  
Versatile Assemblierungsverfahren for DNA constructs of higher order for the integration of molecular function have been described and patented. no uniform concepts found in the practical work of...
DE112012003416T5 A process for the preparation of 2- (4-Methoxycarbonylpyrazol-1-yl) adenosine and 2- (4-ethoxycarbonyl-1-yl) adenosine  
A process for the preparation of 2- (4-Methoxycarbonylpyrazol-1-yl) adenosine of the formula Ia and 2- (4-ethoxycarbonyl-1-yl) adenosine of the formula Ib by reaction of 2-Hydrazinoadenosin of...
DE102012221519A1 Process for the isolation of rhamnolipids  
The invention relates to a method for the isolation of rhamnolipids
DE102012110740A1 Preparing carbohydrate-analogs from five- or six-membered ring glycals, comprises reacting glycal by addition of ketene to corresponding cycloketone, converting cycloketonic to ketoxime, and converting ketoxime in lactam by rearrangement  
Preparing carbohydrate-analogs from five- or six-membered ring glycals, comprises: (a) reacting the glycal by the addition of ketene to the corresponding cycloketone; (b) converting cycloketonic...
DE112012003470T5 A process for preparing 2- [4 - [(methylamino) carbonyl] -1-H-pyrazol-1-yl] adenosinmonohydrat  
A process for preparing 2- [4 - [(methylamino) carbonyl] -1-H-pyrazol-1-yl] adenosinmonohydrat of the formula I by reaction of 2- (4-Methoxycarbonylpyrazol-1-yl) adenosine of the formula III with...
DE102012110664A1 In coatings, bonding agents or adhesives for oxide surfaces usable peptides  
The present invention relates to peptides, particularly dodecapeptides containing coating agents, adhesion promoters or adhesives for oxide surfaces, a multilayer composite or a coated substrate...
DE102012216955A1 A method comprising a continuous crystallization of isomaltulose  
The invention provides methods comprising a continuous crystallisation of isomaltulose.
DE102012103730A1 Detection method for Mycobacterium avium ssp. paratuberculosis  
The present application relates to a method for the specific detection and optionally quantification of Mycobacterium avium ssp. paratuberculosis (MAP) in a sample of an individual. According to...
DE102012101557A1 Using microRNAs or genes as markers for the identification, diagnosis and treatment of individual non-ischemic cardiomyopathies or memory disorders of the heart  
The invention relates to the use of certain microRNAs and / or genes, both individually and in combination of several in the form of profiles as markers to identify individual non-ischemic...
DE102011121238A1 SINGLE DOMAIN ANTIBODIES Clostridium difficile TOXINS  
The invention relates to antigen-binding polypeptides comprising the CDR1, CDR2, and CDR3 region of a VHH domain of a camelid-Heavy chain antibody. The polypeptides bind specifically in the field...
DE102011056679A1 A process for the acid-catalyzed oligomerization of mono- or di-saccharides  
There is a process for the acid-catalyzed oligomerization of mono- and / or di-saccharides is disclosed wherein the mono- or Disa ccharide in the presence of inorganic and / or organic acid to a...
DE102011120550B4 Compositions, methods and kits for the detection of Adenovirusnukleinsäuren  
A method for detecting a specific adenovirus-target nucleic acid in a sample comprising the steps of: (A) contacting a sample suspected of containing at least an adenovirus nucleic acid comprising...
DE69132920C5 Method for the production of filamentous bacteriophage antibody-presenting by use of phagemids and the bacteriophage produced Daduchus  
A filamentous bacteriophage particle, on whose surface a binding molecule is presented, which is a Fab or single-chain Fv antibody molecule comprising a binding domain capable of binding to the...
DE102011055247A1 Multianalyt reporter system  
The invention relates to a mediator probe for binding to a target molecule and / or a detection molecule comprising a probe region and a mediator-region as well as a method for detecting at least...
DE102011117874A1 New dimethyl sulfoxide solvate hydrate of erythromycin useful for combating germs e.g. Bacillus anthracis and Streptococcus and treating lower respiratory tract disorder e.g. bronchitis, pneumonia and whooping cough  
Dimethyl sulfoxide (DMSO) solvate hydrate of erythromycin (I) is new. Dimethyl sulfoxide (DMSO) solvate hydrate of erythromycin of formula (E.xDMSO.yH 2O) (I) is new. E : erythromycin; x :...
DE102011054413A1 Monoclonal anti-idiotype antibody Ganglidiomab  
The present invention relates to an anti-idiotypic antibody which mimics the disialoganglioside GD2. GD2 is expressed on neuroectodermal tumors. Further comprises a corresponding hybridoma cell...
DE102011113652A1 Crystallization of idarubicin  
The patent application relates to a method for preparing crystalline idarubicin hydrochloride comprising the steps of (I) preparing a mixture comprising (a) idarubicin hydrochloride, (b) at least...
DE102011082891A1 Preservative containing glycolipids  
The invention relates to a preservative comprising a glycolipid of the formula (I): in which R1 H or COCH3 means and R2 is the same or different and are H or means, where n is 1, 2 or 3 and R3 is...
DE102011112496A1 4-Methylcatecholderivate and their use  
The invention relates to phenoxy derivatives with glycosidically bound sugar residues, pharmaceutical compositions comprising such compounds, uses of such compounds and compositions, and methods...
DE102011107197A1 Use of a crosslinked sulfonated polymer to separate macromolecules from a solution derived from a biological source, where the crosslinked sulfonated polymer is optionally bonded to a scaffolding containing a sulfonated aryl moiety  
Use of a crosslinked sulfonated polymer for the separation of macromolecules from a solution derived from a biological source, is claimed, where the crosslinked sulfonated polymer is optionally...
DE102011118022A1 Antibodies to the prostate specific antigen stem cells and the use thereof  
The invention relates to recombinant to prostate-specific stem cell antigen (PSCA) antibody binding. The antibody of the invention comprises complementarity determining regions (CDR) having the...
DE102011056606B3 A method for electrochemical detection of nucleic acid hybridization events  
a method for electrochemical detection of nucleic acid hybridization events is described comprising the steps of a) providing a modified surface, the modification consisting in attaching at least...
DE102011103751A1 Crystallizing epirubicin hydrochloride  
The invention relates to crystalline epirubicin hydrochloride and a process for its preparation The process for preparation of crystalline epirubicin hydrochloride comprising the steps of (A)...
DE69314239C5 Process for Stereoselektivglycosylierung  
A process for the synthesis of a β-anomer enriched nucleoside of the formula which, if appropriate in a suitable solvent, performing a nucleophilic SN2-substituting a sulfonyloxy group (Y) of an...
DE602004036672C5 Nucleic acid-based emulsion beads  
Method for enriching an amplicon comprising: (A) distributing an amplification solution, which comprises a sufficient mixture of reagents that are required for carrying out an amplification...
DE102012008759A1 Nucleoside triphosphate conjugates and methods for their application  
The invention describes a new process for the enzymatic labeling of nucleic acid chains (target sequences) with nucleotide conjugates. These nucleotide conjugates are capable of binding under the...