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DE102007018551A1 Preparing gemcitabine comprises reducing a dihydro-furan-2-one compound to give a furan compound, activating the hydroxyl group and reacting with a protected cytosine to give a protected nucleoside and terminal protection of the nucleoside  
Preparation of gemcitabine comprises reducing a dihydro-furan-2-one compound (16A) to give a furan compound (19), activating the hydroxyl group by converting into a sulfonate (mesylate), reacting...
DE102006017492A1 Drug fixation on polymer surfaces  
Of the The present invention relates to compounds according to the general Formula 1, where R1. R2, R3, R4, R5, R6. R7, R8th, R9 and R10 independently selected are selected from the group...
DE202007003784U1 Apparatus for the purification of biomolecules  
device for the purification of biomolecules having by adsorptive separation in a a flat adsorbent (6) Chromatography module (2), the housing (3) at least one inlet (4) and at least one outlet (5)...
DE102006011077A1 A method for degradation of cellulose with nucleophiles  
The This invention describes a method for degradation of cellulose, by dissolving cellulose in an ionic liquid and with a nucleophile treated.
DE102006011076A1 Degradation of poly-, oligo- or di-saccharide or derivative e.g. partial degradation of cellulose for fiber or film production or complete degradation to glucose involves heating solution in ionic liquid e.g. quaternary ammonium compound  
Process for degradation of poly-, oligo- or di-saccharides or their derivatives comprises dissolving the material in ionic liquid(s) and treated at elevated temperature, optionally with addition...
DE102006011075A1 Process for the degradation of cellulose in solution  
The This invention describes a method for degradation of cellulose, by dissolving the cellulose in an ionic liquid and with an acid, optionally the addition of water, treated.
DE102006008701A1 Procedure for transferring biomolecules into a cell, comprises preparing a complex from biomolecule and polymer, and transferring the biomolecule into a cell by contacting the cell with the complex  
Procedure for transferring biomolecule into a cell, comprises preparing a complex from the biomolecule, preferably nucleic acid, and a polymer, which is obtained through reacting an amine-monomer...
DE20122767U1 Massive parallel method for decoding DNA and RNA  
On Nucleotide analogue which comprises: a) a base selected from the group consisting of adenine or an analogue of adenine, Cytosine or an analogue of cytosine, guanine or an analogue of Guanine,...
DE202007003503U1 Galatenoside and their use as antidepressants  
Polygalatenosid the following structure: comprising racemic mixtures of optically active compounds or optically pure R and S stereoisomers, in which R, R 'and R' 'independently H or R1 constitute,...
DE102006001759A1 Synthesis of metal nanoparticles and nanocrystals, useful particularly for silver disinfection of e.g. medical instruments, uses a silicatein protein, also new silicateins and nucleic acid encoding them  
Method for synthesizing nanoparticles and nanocrystals (X) from gold, silver and other transition metals that uses a protein (I), or its metal complex, where (I) comprises an animal, bacterial,...
DE19981703B4 A process for increasing the purity of the racemic form of metallocene  
process to increase the purity of the racemic form of metallocene complexes comprising the steps of (a) adding a compound of LiOH, NaOH and / or KOH or an amine and - water a mixture comprising a...
DE102005063244A1 New 2-nitroimidazole derivatives, useful for detecting hypoxic tissue especially associated with tumors, diabetes, stroke and/or circulatory diseases, have substituent that mediates transport into biological cells  
New 2-nitroimidazole derivatives (I) have a substituent (or vehicle) that mediates transport into biological cells via cellular transport systems. Independent claims are also included for the...
DE102005059242A1 Molecular markers for tumor diagnosis and therapy  
The This invention relates to the diagnosis, prognosis, monitoring and therapy of neoplastic diseases such as tumor diseases, in particular Cancers of the endometrium and their metastases.
DE102005058542A1 Erythruloseester as UV filters  
The Invention relates to compounds according to formula I, wherein X, Y and Z are O, NH or N-alkyl, Sp, Sp ', Sp' 'can be identical or different and are -H, - (CH2)n-, - (CH2)n-C (= O) - (CH2)O-...
DE102005058431A1 Nucleic acid useful as a target for detecting species of yeasts and/or filamentous fungi comprises an elongation factor 3 gene or a fragment thereof  
Nucleic acid (I) comprising the elongation factor 3 gene of yeasts and filamentous fungi or a fragment thereof is new. New nucleic acid (I) comprises a nucleic acid (Ia) with a sequence selected...
DE102005057334A1 A method for isolating nucleic acids from any starting materials  
object the invention is a universal and highly simplified procedure for isolating nucleic acids of nucleic acids containing diverse feedstocks using a combination from buffers with chaotropic...
DE102005046361A1 Detection and differentiation of Salmonella serovars, especially parathyphi B and Java, useful for analysis of e.g. food, clinical and water samples, based on amplification of gene STM3356  
Method for detecting and/or differentiating Salmonella serovars (A). Method for detecting and/or differentiating Salmonella serovars (A) comprises (i) amplifying a region of the STM3356 gene,...
DE102005047736A1 Method to isolate nucleic acid comprises protectively solubilizing biological sample in buffer, adding alcoholic component/non ionic detergent, binding nucleic acid to solid phase, washing with buffer and eluting with salt buffer/water  
Method for isolation of nucleic acid from nucleic acid material comprises protectively solubilizing biological sample in a previously known buffer solution, which is provided with no chaotropic or...
DE102005047736B4 Method and system for isolating nucleic acids from any complex starting materials  
systems without chaotropic and antichaotropic components for isolating nucleic acids from nucleic acids containing materials comprising • at least a per se known Buffer for proteolytic digestion...
DE102005033902B3 Perfluoroalkyl-containing complexes, processes for their preparation, and their use and pharmaceutical compositions containing them  
The Invention relates to the marked in the patent claims, namely perfluoroalkyl Metal complexes with nitrogen-containing groups of the general formula I, to processes for their preparation and...
DE102005046490A1 New nucleic acid molecule comprising promoter, a transcriptable nucleic acid sequence, a first and second nucleic acid sequence for producing modified RNA with transcriptional stability and translational efficiency  
Nucleic acid molecule comprising (in 5'-3' transcription direction) (a) a promoter; (b) a transcriptable nucleic acid sequence or a nucleic acid sequence for inserting in to a transcriptable...
DE102005042828A1 Selected CGPR antagonists, process for their preparation and their use as medicaments  
object the present invention relates to the CGRP-antagonists of general Formulas I, in which R1, R2 and R3 are as defined in claim 1, their Tautomers, the isomers, the diastereomers, deren...
DE112004002170T5 Improved methods and compositions for RNA interference  
process to weaken the expression of a target nucleotide sequence in a eukaryotic Cell, said method comprising: introducing double-stranded RNA (DsRNA) into the eukaryotic cell to the expression of...
DE102005040259A1 A process for recovering nucleic acids from blood  
The This invention relates to an improved process for isolating of nucleic acids in particular from genomic deoxyribonucleic acid (DNA) from blood.
DE102005035461A1 Stable NAD / NADH derivatives  
The Invention relates to stable nicotinamide adenine dinucleotide (NAD / NADH) - or nicotinamide adenine dinucleotide phosphate (NADP / NADPH) derivatives, Enzyme complexes of these derivatives...
DE102005036542A1 CTL prodrug  
The This invention relates to a polypeptide having preferably antitumoral and / or immunomodulatory Zytokineigenschaften through which Processing in vivo is activated, comprising a C-terminal...
DE102006035020A1 Test element for determining analytes, comprises stabilized coenzyme and coenzyme-dependent enzyme, used especially for determination of glucose  
A test element (A) for determination of an analyte comprises: (i) a coenzyme-dependent enzyme (E) or a substrate for E; and (ii) as a coenzyme, a stabilized NAD derivative (I), or its salts or...
DE102006035020B4 Stabilization of NAD / NADH  
A test element for the determination of an analyte comprising (i) a coenzyme dependent enzyme or a substrate for such an enzyme and (ii) as a coenzyme a compound having the following general...
DE102006012317A1 New macromolecular compounds comprising nucleotide and nucleoside building blocks, are useful in enzymatic reactions and nucleic acid analysis  
Macromolecular compounds (I) are new. Macromolecular compounds (I) of formula (Nuc-linker) n-marker, are new. Nuc : nucleotide or nucleoside; linker : a linker component, the Nuc components and...
DE102005033903A1 New perfluoroalkyl-containing metal complexes, useful for production of contrast agents for use in e.g. NMR and X-ray diagnostics, necrosis imaging and in radiodiagnostics and radiotherapy  
Perfluoroalkyl-containing metal complexes (I) are new. Perfluoroalkyl-containing metal complexes of formula K1>-L(Q-R)-N(A)-X-Rf (I), are new. R : mono- or oligosaccharide bound with one hydroxy...
DE102005033903B4 Perfluoroalkyl-containing complexes, processes for their preparation, and their use and pharmaceutical compositions containing them  
perfluoroalkyl Metal complexes having N-alkyl group of the general formula I in which R either one about 1-OH-bonded mono- or oligosaccharide represents the optional is peralkylated, in this case...
DE102005033099A1 New 1,4-benzothiazepine-1,1-Dioxidderivat with improved properties, process for its preparation, pharmaceuticals comprising this compound and its use  
The Invention relates to the compound of formula A and physiologically acceptable Salts. The connection is suitable for. B. as Hypolipidämikum.
DE102005032307A1 Oligomers of free fatty acids and pharmaceutical compositions containing them  
The Invention relates to novel compounds, called out. Free fatty acids derived leave. These are oligomers of at least two saturated or unsaturated free fatty acids natural, semi-synthetic or...
DE102005031755B9 Salmonella spp. binding peptides, nucleic acids coding therefor, their uses, and methods and kits for the enrichment, immobilization and detection of Salmonella spp.  
Salmonella spp. binding peptide selected from the sequences SEQ ID NO. 1 to NO. 3, SEQ ID NO. 5 to NO. 8, SEQ ID NO. 10, SEQ ID NO. 12, SEQ ID NO. 14 to NO. 16, SEQ ID NO. 18, SEQ ID NO. 20 to NO....
DE102005031755A1 New peptides that bind to Salmonella, useful for immobilization, detection, concentration and labeling, optionally derivatized with a pharmaceutical  
Peptide (I) that (i) contains a segment of at least 8 amino acids from any of SEQ ID NOs (1)-(36), all reproduced, and (ii) can bind to Salmonella species is new. Independent claims are included...
DE102005031755B4 Salmonella spp. binding peptides, nucleic acids encoding the Verwenduen and methods and kits for enrichment, immobilization and detection of Salmonella spp.  
Salmonella spp. binding peptide selected from the sequences SEQ ID NO. 1 to NO. 3, SEQ ID NO. 5 to NO. 8, SEQ ID NO. 10, SEQ ID NO. 12, SEQ ID NO. 14 to NO. 16, SEQ ID NO. 18, SEQ ID NO. 20 to NO....
DE112004002408T5 A process for obtaining an enriched population of siRNA-expressing cells  
process for obtaining cells which are capable of inhibiting RNA expressing, said method comprising: introducing at least one nucleic acid in a cell, wherein the at least one nucleic acid in the...
DE102005029998A1 Preparation of spatially resolved substance libraries, preferably polymer libraries, comprises immobilizing chemical reactions and controlling photo-sensitive precursors of activating reagent in fluidic space  
Preparation of spatially resolved substance libraries comprises immobilizing chemical reactions through spatially resolved exposure and controlling photo-sensitive precursors of the activating...
DE102005029811A1 Oligonucleotide arrays, methods for their use, and their use  
The Invention relates to oligonucleotide arrays comprising respectively at least two at least a spacer linked Oligonucleotide and a method using the oligonucleotide arrays for the amplification...
DE102005029811B4 Oligonucleotide arrays, methods for their use, and their use  
oligonucleotide arrays comprising at least two by at least one spacer linked hybridizable oligonucleotide as primer sequences, characterized in that the spacer is selected from functionalized...
DE102006012415A1 An enzymatic process for the recovery of degraded vegetable gum  
The comprises methods for the recovery of degraded vegetable gum the following phases: providing an aqueous solution of a vegetable gum at a temperature ranging between 0 and 80 ° C, the solution...
DE4323567B4 Aucubin for treating a hepatitis B virus infection  
use of Aucubin, the aglycone of Aucubin or a pharmaceutically acceptable salt or the aglycone of aucubin of aucubin for treating a hepatitis B virus infection.
DE20321227U1 New isostructural pseudopolymorph of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin A useful for treating e.g. bacterial and protozoal infections  
An isostructural pseudopolymorph of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin A is new and has the monoclinic space group, average unit cell parameters as given in the specification. An...
DE102006020463B4 A method of removing nucleic acids from a fluid, method for producing adsorber and using Membranadsorbermaterial-blend  
A method for at least partial removal of nucleic acids (18) from a liquid (12), as they occur during the digestion of microorganisms such as bacteria, yeasts, fungi, protozoa or eukaryotic cell...
DE102006020463A1 Procedure for partial removal of nucleic acid from a liquid, which is obtained during lysis of microorganism, comprises binding selective adsorbing component that freely floats in the liquid after pre-set incubation time  
Procedure for at least partial removal of nuclei acids (18) from a liquid (12), which is obtained during the lysis of micro-organism such as bacteria, yeasts, mushrooms, protozoa or cell culture...
DE19781703B4 Effective against tumors Anthracyclindisaccharide, fermentation processes for their preparation and therapeutic composition containing them  
connection of the formula: wherein R represents a -COCH3-, -CHOHCH3- or -COCH2OH group, and their pharmaceutically acceptable addition salts.
DE10227432B4 A process for the separation of carbohydrate carboxylic acids  
process for separating a Carbohydrate ratcarbonsäure of an aqueous dilute solution this mixture of these carbohydrate carboxylic acid and at least one other Carbohydrate carboxylic acid, wherein...
DE102005023829A1 Alleles of opcA gene from corynebacteria  
The Invention relates to mutants and alleles of the gene of coryneform opcA Bacteria encoding Variants of the OpcA subunit of glucose-6-phosphate dehydrogenase (EC: 1.1.1.49), and methods for...
DE102005023761A1 At the Lck-SH3 and Hck SH3 domain-binding peptides  
The Invention relates to the Lck-SH3 and Hck SH3 domain binding Peptides.The proteins according to the sequences 1, 2 and 4 to bind the domain Lck-SH3 and Hck SH3 on, whereby effector molecules of...
DE10228857B4 Tetraether lipids with small head groups, their preparation and use  
tetraether with small head groups of the general formula A, in R and R1, Independently of one another, 1.1. -CH2-I or -CH2-IO31.2. -CH2-Br 1.3. -CH2-ONa 1.4. - [CH2-NX3]+Wherein X is an alkane or...