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DE102013006487A9 Iterative assembly and disassembly of predetermined, artificial DNA constructs and the specific exchange of functional genetic elements  
Versatile Assemblierungsverfahren for DNA constructs of higher order for the integration of molecular function have been described and patented. no uniform concepts found in the practical work of...
DE102013105144A1 The pharmaceutical combination product with an anti-idiotype antibody fragment  
The invention relates to a pharmaceutical combination preparation (10), in particular to suppression of an immune response, preferably a humoral immune response against a therapeutic organism...
DE112004000265B4 Novel photolabile protecting groups for improved methods for the preparation of oligonucleotide arrays  
Use of a compound having the general formula (1): in which R1 COOY, wherein Y is selected from the group consisting of an optionally substituted alkyl group having up to 10 carbon atoms with the...
DE102013006487A1 Iterative assembly and disassembly of predetermined, artificial DNA constructs and the specific exchange of functional genetic elements  
Versatile Assemblierungsverfahren for DNA constructs of higher order for the integration of molecular function have been described and patented. no uniform concepts found in the practical work of...
DE112012003416T5 A process for the preparation of 2- (4-Methoxycarbonylpyrazol-1-yl) adenosine and 2- (4-ethoxycarbonyl-1-yl) adenosine  
A process for the preparation of 2- (4-Methoxycarbonylpyrazol-1-yl) adenosine of the formula Ia and 2- (4-ethoxycarbonyl-1-yl) adenosine of the formula Ib by reaction of 2-Hydrazinoadenosin of...
DE102012221519A1 Process for the isolation of rhamnolipids  
The invention relates to a method for the isolation of rhamnolipids
DE10362249B4 C1-selective oxidation of oligosaccharides and the use of a carbon supported gold catalyst for this oxidation  
Process for the selective oxidation of the C1-aldehyde group of a used as starting material oligosaccharide, oligosaccharide mixture or an oligosaccharide or composition containing an...
DE102012110740A1 Preparing carbohydrate-analogs from five- or six-membered ring glycals, comprises reacting glycal by addition of ketene to corresponding cycloketone, converting cycloketonic to ketoxime, and converting ketoxime in lactam by rearrangement  
Preparing carbohydrate-analogs from five- or six-membered ring glycals, comprises: (a) reacting the glycal by the addition of ketene to the corresponding cycloketone; (b) converting cycloketonic...
DE112012003470T5 A process for preparing 2- [4 - [(methylamino) carbonyl] -1-H-pyrazol-1-yl] adenosinmonohydrat  
A process for preparing 2- [4 - [(methylamino) carbonyl] -1-H-pyrazol-1-yl] adenosinmonohydrat of the formula I by reaction of 2- (4-Methoxycarbonylpyrazol-1-yl) adenosine of the formula III with...
DE102012110664A1 In coatings, bonding agents or adhesives for oxide surfaces usable peptides  
The present invention relates to peptides, particularly dodecapeptides containing coating agents, adhesion promoters or adhesives for oxide surfaces, a multilayer composite or a coated substrate...
DE102006053385B4 Enterococcus faecalis antigen  
Enterococcus faecalis strain type 5 antigen, at least one disaccharide unit comprising, having the following formula: where R1 OH, X = O, Y = O and CA lactyl is.
DE102012216955A1 A method comprising a continuous crystallization of isomaltulose  
The invention provides methods comprising a continuous crystallisation of isomaltulose.
DE102010006245B4 Mayamycin compounds, processes for their preparation, their uses and those containing cosmetic product  
Compound of general structure in which R is a hydrogen atom (H) or an unsubstituted, monosubstituted or polysubstituted C1-C20Alkyl, said alkyl straight, branched, may be cyclic or partially...
DE102012103730A1 Detection method for Mycobacterium avium ssp. paratuberculosis  
The present application relates to a method for the specific detection and optionally quantification of Mycobacterium avium ssp. paratuberculosis (MAP) in a sample of an individual. According to...
DE102011120550B4 Compositions, methods and kits for the detection of Adenovirusnukleinsäuren  
A method for detecting a specific adenovirus-target nucleic acid in a sample comprising the steps of: (A) contacting a sample suspected of containing at least an adenovirus nucleic acid comprising...
DE102008025328B4 Compositions and methods for amplification of HIV viruses by multiplex PCR in multiple genomes areas  
A method for the detection of HIV-1 and HIV-2 derived from in blood samples, comprising a) provide from blood-derived samples, b) concentrating the blood-derived sample, c) extraction of viral...
DE102012101557A1 Using microRNAs or genes as markers for the identification, diagnosis and treatment of individual non-ischemic cardiomyopathies or memory disorders of the heart  
The invention relates to the use of certain microRNAs and / or genes, both individually and in combination of several in the form of profiles as markers to identify individual non-ischemic...
DE102007010252B4 Control genes for normalization of gene expression analysis data  
Control gene set for the normalization of gene expression analysis data from blood samples of patients with diseases with systemic immune response, especially SIRS, sepsis, severe sepsis, septic...
DE102011121238A1 SINGLE DOMAIN ANTIBODIES Clostridium difficile TOXINS  
The invention relates to antigen-binding polypeptides comprising the CDR1, CDR2, and CDR3 region of a VHH domain of a camelid-Heavy chain antibody. The polypeptides bind specifically in the field...
DE102011056679A1 A process for the acid-catalyzed oligomerization of mono- or di-saccharides  
There is a process for the acid-catalyzed oligomerization of mono- and / or di-saccharides is disclosed wherein the mono- or Disa ccharide in the presence of inorganic and / or organic acid to a...
DE102006020463B4 A method of removing nucleic acids from a fluid, method for producing adsorber and using Membranadsorbermaterial-blend  
A method for at least partial removal of nucleic acids (18) from a liquid (12), as they occur during the digestion of microorganisms such as bacteria, yeasts, fungi, protozoa or eukaryotic cell...
DE69132920C5 Method for the production of filamentous bacteriophage antibody-presenting by use of phagemids and the bacteriophage produced Daduchus  
A filamentous bacteriophage particle, on whose surface a binding molecule is presented, which is a Fab or single-chain Fv antibody molecule comprising a binding domain capable of binding to the...
DE4321904B4 A process for chromatographic purification and separation of Nucleinsäuregemischen  
A process for chromatographic purification and separation of Nucleinsäuregemischen from biological sources such as cell cultures, tissues, body fluids, microorganisms or viruses to be separated by...
DE102011055247A1 Multianalyt reporter system  
The invention relates to a mediator probe for binding to a target molecule and / or a detection molecule comprising a probe region and a mediator-region as well as a method for detecting at least...
DE102011117874A1 New dimethyl sulfoxide solvate hydrate of erythromycin useful for combating germs e.g. Bacillus anthracis and Streptococcus and treating lower respiratory tract disorder e.g. bronchitis, pneumonia and whooping cough  
Dimethyl sulfoxide (DMSO) solvate hydrate of erythromycin (I) is new. Dimethyl sulfoxide (DMSO) solvate hydrate of erythromycin of formula (E.xDMSO.yH 2O) (I) is new. E : erythromycin; x :...
DE4420157B4 New growth / differentiation factor of the TGF-β family  
Use of a pharmaceutical composition comprising a protein which is encoded by a DNA sequence which (A) nucleotides 1783 to 2142, 640-2142 or 1837-2142 of SEQ ID NO: 1, (B) one of the sequences from...
DE102011054413A1 Monoclonal anti-idiotype antibody Ganglidiomab  
The present invention relates to an anti-idiotypic antibody which mimics the disialoganglioside GD2. GD2 is expressed on neuroectodermal tumors. Further comprises a corresponding hybridoma cell...
DE102011113652A1 Crystallization of idarubicin  
The patent application relates to a method for preparing crystalline idarubicin hydrochloride comprising the steps of (I) preparing a mixture comprising (a) idarubicin hydrochloride, (b) at least...
DE102011082891A1 Preservative containing glycolipids  
The invention relates to a preservative comprising a glycolipid of the formula (I): in which R1 H or COCH3 means and R2 is the same or different and are H or means, where n is 1, 2 or 3 and R3 is...
DE102011112496A1 4-Methylcatecholderivate and their use  
The invention relates to phenoxy derivatives with glycosidically bound sugar residues, pharmaceutical compositions comprising such compounds, uses of such compounds and compositions, and methods...
DE102011107197A1 Use of a crosslinked sulfonated polymer to separate macromolecules from a solution derived from a biological source, where the crosslinked sulfonated polymer is optionally bonded to a scaffolding containing a sulfonated aryl moiety  
Use of a crosslinked sulfonated polymer for the separation of macromolecules from a solution derived from a biological source, is claimed, where the crosslinked sulfonated polymer is optionally...
DE102011118022A1 Antibodies to the prostate specific antigen stem cells and the use thereof  
The invention relates to recombinant to prostate-specific stem cell antigen (PSCA) antibody binding. The antibody of the invention comprises complementarity determining regions (CDR) having the...
DE102011056606B3 A method for electrochemical detection of nucleic acid hybridization events  
a method for electrochemical detection of nucleic acid hybridization events is described comprising the steps of a) providing a modified surface, the modification consisting in attaching at least...
DE102011103751A1 Crystallizing epirubicin hydrochloride  
The invention relates to crystalline epirubicin hydrochloride and a process for its preparation The process for preparation of crystalline epirubicin hydrochloride comprising the steps of (A)...
DE69314239C5 Process for Stereoselektivglycosylierung  
A process for the synthesis of a β-anomer enriched nucleoside of the formula which, if appropriate in a suitable solvent, performing a nucleophilic SN2-substituting a sulfonyloxy group (Y) of an...
DE602004036672C5 Nucleic acid-based emulsion beads  
Method for enriching an amplicon comprising: (A) distributing an amplification solution, which comprises a sufficient mixture of reagents that are required for carrying out an amplification...
DE102012008759A1 Nucleoside triphosphate conjugates and methods for their application  
The invention describes a new process for the enzymatic labeling of nucleic acid chains (target sequences) with nucleotide conjugates. These nucleotide conjugates are capable of binding under the...
DE10352433B4 Polypeptide a Silicatein ß from Suberites domuncula, nucleic acid coding therefor, their uses, this nucleic acid vector comprising and expressing this polypeptide host cell  
Polypeptide a Silicatein β from Suberites domuncula according to SEQ ID NO. 1, recombinant polypeptide comprising an amino acid sequence of β-Silicatein domain identical to the sequence shown in...
DE112010004821T5 Processing of amplified DNA fragments for sequencing  
A processing method for trimming the ends of DNA fragments to expose the inner DNA portion for forwarding the original DNA sequence information that allows the application of next generation...
DE102011001743A1 Process for the separation / purification of Biomolekühlen  
The invention relates to an aqueous two-phase extraction methods, wherein the second aqueous phase is in the pores of a porous material.
DE102011009470A1 Biologically active nucleotide molecules for targeted killing of cells, using the same and application kit  
The task was to reliably and effectively as possible kill cells in a wide range of applications, effective in the body, without the aforementioned disadvantages occur a known chemical, physical,...
DE10113776B4 An isolated streptavidinbindendes competitively elutable peptide, this complete fusion peptide, nucleic acid coding therefor, expression vector, to methods for producing a recombinant fusion protein, and methods for the detection and / or for the recovery of the fusion protein  
An isolated streptavidinbindendes competitively elutable peptide comprising at least two streptavidinbindende individual modules, wherein the distance between the two individual modules is 0 and a...
DE102011006610B3 Aptamers that are specific for immunoglobulin binding cell wall proteins  
The invention relates to an aptamer that containing of protein A, G or L, Protein A, G or L substances and containing at Protein A, G or L microorganisms, in particular Staphylococcus aureus,...
DE102010055566A1 New compounds conjugating gyrase-inhibiting substances with catechol structural units, are gyrase inhibitors, useful as biologically active substances, and for treating bacterial infection  
Compounds (Q) conjugating gyrase-inhibiting substances with catechol structural units, are new. An independent claim is included for the preparation of (Q). ACTIVITY : Antibacterial. MECHANISM OF...
DE10237517B4 A process for the enrichment or depletion of biomolecules from liquid or fluid media using Schichtdoppelhydroxiden and use of other on a layered double hydroxide or incorporated biomolecules as inorganic Vector  
A process for the removal or recovery or purification of at least one biomolecule, which contains, as building blocks nucleotides, nucleosides, amino acids, monosaccharides and / or fatty acids...
DE102011006612B3 Aminoglycoside specific aptamers  
The invention relates to aptamers that bind to one or more compounds from the group of aminoglycosides, uses the aptamers and methods for detection and enrichment of compounds from the group of...
DE102010038842A1 New aptamer that specifically binds to human tau protein or its fragment, useful e.g. in vitro for isolating, purifying and/or detecting tau protein, and to treat cerebral infarction, pick disease and/or progressive supranuclear palsy  
Aptamer that specifically binds to human tau protein or its fragment, is new. Independent claims are included for: (1) kit comprising the aptamer; (2) a method for the purification of human tau...
DE102010033102A1 Determining a locus change i.e. single nucleotide polymorphism on male cattle, comprises determining the weight and/or the proportions of a fetus by molecular markers  
Determining a locus change on male cattle, comprises determining the weight and/or the proportions of a fetus by molecular markers. Independent claims are included for: (1) primers for detection...
DE102009013748B4 Determination of interactions constant antibody portions with Fc gamma receptors  
A recombinant expression vector comprising sequences for the recombinant expression of at least one fusion protein on the surface of a mammalian cell comprising a) an extracellular portion of a...
DE102009024757B4 Methods and apparatus for controlling a chemical reaction by means of pressure using high-pressure optimized biocomponents  
A method for controlling a chemical reaction by means of compressed using high pressure optimized bio, where a combination of high-pressure-optimized and low-pressure-optimized bio, which can each...