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DE10126164A1 For metD gene coding nucleotide sequences  
The invention relates to nucleotide sequences from coryneform bacteria which code for the metD gene and to a process for the fermentative preparation of L-amino acids using coryneform bacteria in...
DE10124342A1 Amplification method for Yersinia pestis and Yersinia pseudotuberculosis, useful for their rapid detection and differentiation, also new primers and probes  
Amplification and hybridization method for detecting, and/or differentiating between, Yersinia pestis and Y. pseudotuberculosis. Method for detecting, and/or differentiating between, Yersinia...
DE10217084A1 Separation of DNA molecules  
The present invention relates to a process for the separation of nucleic acid molecules, preferably of offenzirkulären and super helical plasmid DNA and RNA molecules, solution comprising the...
DE10123503A1 Use of Belamcanda chinensis extract, or its active ingredient, for treating sex hormone-dependent urogenital disorders and prostatic hyperplasia  
Use of extract of Belamcanda chinensis to prepare an estrogen-like, organ-selective composition, with little or no uterotropic activity, for treating sex hormone-dependent disorders of the...
DE10122862A1 New nucleic acid that binds to gonadotropin releasing hormone, useful for treating and diagnosing overproduction of hormones, e.g. endometriosis  
Nucleic acid (I) that binds to gonadotropin releasing hormone (GnRH), especially the human peptide, is new. Independent claims are also included for the following: (1) preparing and/or identifying...
DE10122847A1 New nucleic acid that binds to staphylococcal enterotoxin B, useful for treating and diagnosing e.g. septic shock, identified by the SELEX method  
Nucleic acid (I) that binds to enterotoxin B (Eb) of Staphylococcus, especially S. aureus, is new. Independent claims are also included for the following: (1) preparing and/or identifying nucleic...
DE10120797A1 A process for the analysis of nucleic acid chains  
The invention relates to a method for the analysis of nucleic acid chains. Basis of the method is the detection of fluorescence signals of individual, labeled with dyes nucleotide molecules, which...
DE10122990A1 Use of alkanes for contamination-free purification or separation of biopolymers  
The present invention relates to the use of alkanes for the contamination-free purification or separation of biopolymers.
DE10121741A1 Process for the synthesis carrier poor · 18 · F labeled compounds  
The invention relates to a method for the synthesis of <18>F marked compounds which are low in carriers. Nucleophilic phase-transfer catalyzed <18>F- fluoridation was previously the only way to...
DE10116829A1 Neuropeptide binding nucleic acids  
The present invention relates to a neuropeptide Y binding nucleic acid and the use thereof.
DE10122255C1 A process for the production of surfactant mixtures  
The invention relates to a method for the production of surface active agent mixtures containing alkyl/ and/or alkenyl oligoglycoside/ether carboxylic acids. The invention is characterized in that...
DE10121724A1 gemini  
The invention relates to Gemini surfactants, optionally in combination with customary in dishwashing detergents and cleaning ingredients, optionally in with other non-ionic surfactants and anionic...
DE10121722A1 Gemini surfactants in rinse aids  
The invention relates to Gemini surfactants, optionally in combination with customary in rinse aid ingredients, optionally with other non-ionic surfactants and anionic surfactants, and the use of...
DE10121571A1 Solid-phase synthesis of oligomers  
The invention relates to a method for producing molecule libraries at predetermined locations on a substrate surface by means of sequential chemical reactions involving the use of combinatorial...
DE10121225A1 Identifying animals, particularly pigs, with desirable breeding traits comprises analyzing polymorphisms in the alpha-inhibin and betaA-inhibin/activin genes  
Investigating animals to identify those with greater probability of having advantageous reproductive, growth and carcass traits comprising determining polymorphisms in the alpha -inhibin (INHA)...
DE10118043A1 Highly specific detection system  
The invention relates to an improved in situ hybridization method for detecting nucleotide sequences coding for light lambda and kappa chains and to means for carrying out said method.
DE10201458A1 New proteins involved in isoprenoid biosynthesis, useful in screening for inhibitors, also new intermediates, potential therapeutic agents, nucleic acids and antibodies  
A protein (P1) capable of enzymatic conversion of 2C-methyl-D-erythritol-2,4-cyclodiphosphate (I) to 1-hydroxy-2-methyl-2-butenyl-4-diphosphate (II), especially the (E) form, is new. Independent...
DE10162387A1 For the rpoB gene coding nucleotide sequences  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence selected from the group DOLLAR A a) polynucleotide which is at least 70% identical to a polynucleotide...
DE10119179A1 New nucleic acid, useful for diagnostic detection of fungal RNA, specifically from Aspergillus, in clinical samples by nucleic acid sequence-based amplification  
Nucleic acid (A) comprising a 22, 24, or 23 base pair sequence (S1), given in the specification, or a sequence that binds to a sequence to which (S1) also binds, is new. Independent claims are...
DE10117381A1 Production of polyclonal, monospecific antibodies against uPAR variants del4, del5 and del4 + 5 and their use for diagnostic and therapeutic purposes  
The invention relates to the production of specific antibodies to detect human tumour-associated urokinase-type plasminogene activator receptor (uPAR) deletion variants in biological samples and...
DE10115749A1 Control plasmid and method for the detection of mycoplasma contamination in biological material  
The invention relates to a method for detecting mycoplasma in biological material, comprising the following steps: a) the mycoplasma are lysed in the biological material by heat treatment, b) the...
DE10115507A1 Method of encoding information in the nucleic acids of a genetically modified organism  
A method of producing a genetically engineered organism, by (a) incorporating into said organism a functional DNA sequence and (b) incorporating into said organism a non-functional DNA sequence,...
DE10114999A1 D-carbamoylase from Arthrobacter crystallopoietes DSM 20117  
The present invention relates to a new D-carbamoylase and the gene sequences which code for this from the organism Arthrobacter crystallopoietes DSM 20117. Plasmids, vectors, microorganisms,...
DE10151071A1 Nucleic acids stabilized against exonucleases, useful for protein production in cell-free or cellular systems, contains molecules attached to bulky specific binding partners  
Nucleic acids (I) stabilized against degradation by exonuclease comprising: (a) sequence encoding a specific peptide or protein; (b) optionally a promoter that controls expression of (i); and (c)...
DE10115748A1 Control plasmid, useful in detection of Mycoplasma pneumoniae by polymerase chain reaction, includes amplicon between specific primer sequences  
Control plasmid (A) that includes (i) primers (P) that recognize a species-specific segment (S) of the P1 adhesin protein gene of Mycoplasma pneumoniae and (ii) between P, an amplicon containing...
DE10113776B4 An isolated streptavidinbindendes competitively elutable peptide, this complete fusion peptide, nucleic acid coding therefor, expression vector, to methods for producing a recombinant fusion protein, and methods for the detection and / or for the recovery of the fusion protein  
An isolated streptavidinbindendes competitively elutable peptide comprising at least two streptavidinbindende individual modules, wherein the distance between the two individual modules is 0 and a...
DE10113776A1 Sequentially arranged streptavidinbindende modules as affinity tag  
The present invention relates to sequentially arranged streptavidin-binding binding modules which may in particular be used as affinity tags. The affinity tags comprise at least two individual...
DE10113265A1 Nucleic acids stabilized against exonucleases, useful for protein production in cell-free or cellular systems, contains molecules attached to bulky specific binding partners  
Nucleic acids (I) stabilized against degradation by exonuclease comprising: (a) sequence encoding a specific peptide or protein; (b) optionally a promoter that controls expression of (i); and (c)...
DE10112348A1 Nukleotidträger the diagnosis and treatment of oral diseases  
The invention relates to a Nukleotidträger with probes for at least one human and microbial reference sequence or to a complementary sequence to the reference sequence.
DE10111682A1 Caloporoside derivatives, processes for their preparation and their use  
The present invention relates to novel active compounds (Caloporisid derivatives), of the microorganism Gloeoporus dichrous (Fr.:Fr.) Bres. ST001714, DSM 13784 produced during fermentation,...
DE10111681A1 An improved process for the preparation of pentopyranosylnucleosides  
The present invention relates to an improved process for preparing pentopyranosylnucleosides in which a significant improvement can be achieved, and simplification of the process step described in...
DE10112992A1 New isolated polynucleotide from coryneform bacteria, useful for increasing production of amino acids, comprises extended genes for 1- or 6- phosphofructokinase  
Isolated polynucleotide (I) from coryneform bacteria (CB) comprising a sequence that: (a) encodes 1- and/or 6- phosphofructokinase (1- or 6-PFK); and (b) is extended by up to 700 base pairs both...
DE10110685A1 Oligonucleotide chip, useful for gene expression analysis of Saccharomyces cerevisiae, comprises an array of probes specific for S. cerevisiae open reading frames  
New oligonucleotide chip (A) having many probe locations (PL), each carrying many probe molecules (I) having, for a given PL, the same sequence, in which at least one (I) has a sequence of at...
DE10112401A1 Alcohol dehydrogenase and their use  
The invention relates to a novel alcohol dehydrogenase (ADHF1) from Pseudomonas fluorescens (DSM 50106), and their functional variants and a method for the selective reduction of ketones to the...
DE10111433A1 Replication-competent molecular clones of porcine endogenous retrovirus of Class A and Class B, derived from porcine and human cells  
The present invention relates to functional, replication-competent full-length proviral PERV-A and PERV-B clones isolated directly from the pig genome, i.e. "native" PERV and allows the comparison...
DE10036068C2 A process for the enzymatic production of monosaccharides rare, especially tagatose  
The invention relates to the purely enzymatic production of rare in nature occurring and chemically producible only by complicated and costly process monosaccharides such as tagatose, fuculose and...
DE10109466B4 Method and means for modification of human angiogenesis  
process to induce angiogenic processes in tissues of a mammalian organism, comprising the steps of: - Preparation of a ternary complex by complexing a nucleic acid molecule as a functional...
DE10109466A1 Method and means for modification of human angiogenesis  
The invention relates to methods and agents for modifying human angiogenesis, whereby the agents used in these methods can be nucleic acids, nucleic acid complexes (angiotropin) or antibodies that...
DE10109166A1 Avilamycin derivatives  
The invention relates to avilamycin derivatives, genetic engineering, biosynthetic methods for the production thereof, medicaments containing said compounds and the utilization of said compounds...
DE10108851A1 Use of 5'-substituted nucleosides and / or their prodrugs for the resistance-free therapy of infectious diseases  
The invention relates to the use of 5-substituted nucleosides and/or prodrugs thereof together with at least one active substance in order to produce a medicament or combination preparation used...
DE10063387A1 New elongase gene extends 16, 18 and 20 carbon fatty acids, useful to manipulate plants to produce polyunsaturated fatty acids for the foodstuffs, cosmetics and pharmaceutical industries  
An isolated nucleic acid from a plant or algae which encodes a polypeptide which extends a C16, C18 or C20 fatty acid having at least two double bonds by at least two carbon atoms, is new....
DE10109657A1 A process for the preparation of (E) -5- (2-bromovinyl) deoxyuridine--2`  
The present invention relates to the preparation of (E)-5-(2-bromovynyl)-2'-deoxyuridine (Brivudine) characterized in that halogen-free solvents selected form esters or cyclic ethers are used in...
DE10162386A1 For the rpsL gene coding nucleotide sequences  
The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70% to a...
DE10109517A1 Process for the preparation of gene libraries  
The invention relates to a method for producing gene libraries, wherein a defined number of juxtapositioned nucleotides are exchanged in genes and gene libraries are produced, coding for protein...
DE10108212A1 Fusion protein for secretion of value protein in bacterial supernatants  
The invention relates to fusion proteins comprising a fusion part and a protein of interest, the combination of the two proteins leading to the fusion protein being secreted into the supernatant...
DE10108211A1 Use of fusion proteins whose N-terminal portion consists of a hirudin derivative for the production of recombinant proteins via secretion by yeasts  
The invention relates to an expression cassette of the form Px-Sx-Bn-(ZR)-Hir (AsmR)-protein (Y) - T, where Px is any promoter DNA sequence, selected in such a way that optimal yields of the...
DE10106370A1 Oligonucleotide probes for the detection of periodontal bacteria by means of in situ hybridization  
The invention relates to oligonucleotide probes used for the species-specific identification of parodontophathogenic bacteria by in situ hybridization. The invention further relates to...
DE10106199A1 A method for isolating nucleic acids from a nucleic acid containing liquid sample  
A method for isolating nucleic acids from a nucleic acid containing liquid sample using a filter device, the pores through which is allowed to flow through the course of isolating the sample, the...
DE10104722A1 A process for the fermentative production of cysteine, cystine and glutathione  
The invention relates to a method for detecting genes and DNA- sequences which code for the enzyme serine acetyltransferase (SAT) and are suitable for the production of cysteine by fermentation....
DE10104350A1 A process for producing flavone derivatives  
The invention relates to a method for producing flavone derivatives, wherein a 2 hydroxyacetophenone compound is metallised with a lithium compound at low temperatures and subsequently reacted...