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DE10152615A1 Zuckerester  
Vorgeschlagen werden neue Zuckerester, die man erhält, indem man Zuckersäuren in Gegenwart von Lipasen mit Alkoholen verestert.
DE10152017A1 Arrays mit Hairpin-Strukturen  
The invention relates to arrays of nucleic acids immobilized on a carrier, which are present at least partly in the form of secondary structures such as hairpin structures. The invention also...
DE10150677A1 New nucleic acid encoding fungal mitogen-activated protein kinase, useful as target for identifying fungicides for plant protection, is from Fusarium graminearum  
Nucleic acid sequence, encoding a MAP kinase, (I) comprises (a) sequences (S1) or (S2), of 556 and 490 nucleotides, reproduced; (b) a functional equivalent of (a); (c) a fragment of (a); or (d) a...
DE10150676A1 Neue chemisch-induzierbare Promotoren  
The invention relates to methods for the chemically inducible expression of nucleic acid sequences, preferably in plants. Said invention also relates to novel chemically inducible promoters,...
DE10150121A1 Echtzeitdetektion von DNA-Amplifikationsprodukten  
The invention relates to a method for the real-time detection of DNA amplification products. The invention also relates to partially double-stranded oligonucleotides, which are used during the...
DE10139062A1 Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien  
Die Erfindung betrifft ein Verfahren zur Herstellung von L-Aminosäuren, bei dem man folgende Schritte durchführt: DOLLAR A a) Fermentation der die gewünschte L-Aminosäure produzierenden...
DE10249024A1 Preparing aqueous nucleic acid-rich extracts, useful in cosmetics e.g. for reducing aging of skin, includes extraction in presence of cellulase then treatment with protease  
Method for preparing a nucleic acid-rich aqueous extract (A) from plant materials, especially plant embryos or seeds rich in DNA and RNA comprises: (i) extraction in aqueous medium in presence of...
DE10150783A1 Splicing als Target zum Identifizieren neuer Wirkstoffe  
Die vorliegende Erfindung betrifft neue Desoxyribonukleinsäure(DNA)-Konstrukte, Vektoren und Wirtsorganismen, die diese DNA-Konstrukte enthalten und durch Einsatz in bestimmten Verfahren geeignet...
DE10142643A1 Detektion von Wechselwirkungen auf Sonden-Arrays  
Die Erfindung betrifft ein Verfahren zum Nachweis von Wechselwirkungen zwischen Sondenmolekülen auf Sonden-Arrays, bei dem auf die Markierung der Targetmoleküle verzichtet werden kann. Ferner...
DE10125537A1 Identifying herbicides and plant growth regulators, from ability to inhibit specific genes, also use of these genes to prepare herbicide-resistant transgenic plants  
Identifying compounds (A) with herbicidal activity from ability to reduce or block expression or activity of gene products of specific nucleic acid sequences (I) or amino acid sequences (II)...
DE10146589A1 Neue Mutanten der Formiatdehydrogenase aus Candida boidinii  
Die vorliegende Erfindung befaßt sich mit neuen verbesserten rekombinant hergestellten Enzymen, insbesondere mit rec-FDHs. Durch gerichtete Evolution ist es gelungen, katalytisch aktivere und...
DE10145226A1 Herstellung von trägergebundenen Molekülen  
The invention relates to a support for binding assays, whereby the assignment and coupling of trap molecules occurs on the solid phase by simple coating of a surface (support), pretreated in a...
DE10144346A1 TT-Virus-Sequenzen in menschlichen Tumorgeweben, Mittel zu deren Nachweis sowie Tumortherapie  
Beschrieben werden DNA-Sequenzen, die das Genom eines Tumor-assoziierten TT-Virus umfassen, oder Fragmente davon. Die vorliegende Erfindung betrifft ferner von diesen DNA-Sequenzen kodierte...
DE10140651A1 Diagnostic kit, useful for assessing a subject's tolerance of drugs, comprises reagents for determining alleles of genes encoding detoxification enzymes  
Diagnostic kit (A) for determining tolerance of pharmaceuticals in humans. Diagnostic kit (A) for determining tolerance of pharmaceuticals in humans comprises two pairs of oligonucleotide (ON)...
DE10144647A1 New allosterically regulatable hairpin ribozyme, useful for identifying compounds that bind specific targets, has extra sequence between substrate binding and catalytic domains  
Allosterically regulatable hairpin ribozyme (I) is new. Independent claims are also included for: (1) polynucleotide (II) comprises a hairpin ribozyme having a substrate-binding domain A and a...
DE10144355A1 Identifying agents that inhibit the function of specific RNA, useful e.g. for treating human or feline immune deficiency virus, comprises using a target-reporter construct prepared from a reporter ribozyme domain  
Identifying compounds (A1) that bind specifically to a particular RNA target motif (II) so as to inhibit or eliminate its function. Identifying compounds (A1) that bind specifically to a...
DE10144264A1 Aqueous detergent formulation, useful in cosmetics, e.g. shampoo, hair lotion, foam bath or shower formulation, contains N-acylamino-acid and/or salt and polyol and/or polyol fatty acid ester  
Aqueous detergent formulation contains: (a) N-acylamino-acid (I) and/or salt (IA), and (b) polyol (II) and/or polyol fatty acid ester (III). Independent claims are also included for: (A) the...
DE10129484A1 Alkyl- und/oder Alkenyloligoglycosid-Zubereitungen mit verminderten Magnesiumsalzkonzentrationen  
Vorgeschlagen werden Alkyl- und/oder Alkenyloligoglycosid-Zubereitungen mit einer Magnesiumsalzkonzentration kleiner als 10 ppm - bezogen auf die Gesamtzusammensetzung -, dadurch erhältlich, dass...
DE10129332A1 New sialic acid-binding Ig-like lectin (Siglec) inhibitors with increased activity, useful for e.g. treating inflammation, multiple sclerosis, cancer or viral disease, comprises C-9 amino-substituted neuraminic acid derivatives or analogs  
New sialic acid-binding Ig-like lectin (Siglec) inhibitors comprise of neuraminic acid derivatives (including aza, carba or thia analogs) (I) containing an optionally substituted amino group at...
DE10142743A1 Nucleotide chip containing probes against dimorphism-specific transcripts, useful for diagnosing Candida infections and transition from yeast to hyphal forms  
Nucleotide chip (A) comprises a solid carrier on which is fixed at least one nucleic acid (NA) suitable for identifying a transcript of a gene that encodes a dimorphism-specific protein....
DE10141300A1 Markierungsfähige Verbindungen zur einfachen Synthese von 3'-[·18·F]Fluor-3'-deoxythymidin und Verfahren zu deren Herstellung  
Disclosed are compounds of formula (I), wherein R represents Br, J or R<1>-SO3, wherein R<1> is an unsubstituted or substituted C1-C5-alkyl or an unsubstituted phenyl, X is O or NR'', wherein R''...
DE10139283A1 Verfahren und Nukleinsäuren zur Analyse von Colon-Krebs  
Die vorliegende Erfindung betrifft chemisch modifizierte genomische Sequenzen, Oligonukleotide und/oder PNA-Oligomere zur Detektion des Cytosin-Methylierungsstatus genomischer DNA wie auch zwei...
DE10139730A1 Verfahren zur Herstellung CNA  
The invention relates to a novel method for producing CNA oligomers and artificial supramolecular CNA-p-RNA pairing systems. The invention also relates to the use of the same, especially in...
DE10138686A1 Verwendung einer Polyester-Zusammensetzung als Hydraulikfluid  
Die vorliegende Erfindung betrifft die Verwendung von Polyestern, die aus mindestens einem Kohlenhydrat und mindestens einer Carbonsäure bestehen, und Gemischen davon als Hydraulikfluid.
DE10138092A1 Verfahren zur Immobilisierung von Verbindungen und Anordnung von immobilisierten Verbindungen  
Die vorliegende Erfindung betrifft ein Verfahren zur Immobilisierung von Verbindungen auf einer Oberfläche, umfassend die Schritte DOLLAR A - Bereitstellen einer zu immobilisierenden Verbindung...
DE10137374A1 Verfahren zur Herstellung von Arachidonsäure in transgenen Organismen  
Die Erfindung betrifft ein Verfahren zur Herstellung von Arachidonsäure in transgenen Organismen, insbesondere in transgenen Pflanzen und Hefen. Des weiteren betrifft die Erfindung DNA-Sequenzen,...
DE10139455A1 New polynucleotide sequences from Ashbya gossypii, useful for improving response of A. gossypii to external factors and particularly for improving production of vitamin B2  
Polynucleotide (I) encodes a protein (II) that is associated with transmembrane transport and/or is a transmembrane protein and is isolatable from Ashbya gossypii. Independent claims are also...
DE10136656A1 Biochip useful e.g. for determining gene expression patterns, and for selecting probes, comprises probes specific for genes active in rat liver  
A biochip has many probe positions, each containing many molecules of a nucleic acid probe (I), where one (I) has a length of 20 bases identical with, or complementary to, a segment of a rat liver...
DE10135098A1 Verfahren zur Herstellung von peracylierten 1-O-Glycosiden  
Die Erfindung betrifft ein Verfahren zur Herstellung von peracylierten 1-O-Glycosiden der allgemeinen Formel I oder deren Salzen DOLLAR F1 in der DOLLAR A Zucker·1· ein in 1-OH-Position...
DE10134660A1 New isolated nucleic acid encoding desaturase enzymes from pomegranate, useful for recombinant production of unsaturated fatty acids, for e.g. the production of food, animal feeds and pharmaceuticals  
New isolated nucleic acid (I) encoding a polypeptide (II) with desaturase activity comprises: (a) a 1464 bp sequence (2); (b) a sequence deduced by reverse translation from a 374 amino acid (aa)...
DE10133915A1 Neue Oligoribonucleotid-Derivate zur gezielten Hemmung der Genexpression  
The invention relates to oligoribonucleotide derivatives that have, at the 3' end, a 2'5'-linked oligoribonucleotide radical without a 5' phosphate radical and to their use for the targeted...
DE10133858A1 Synthetische doppelsträngige Oligonucleotide zur gezielten Hemmung der Genexpression  
The invention relates to oligonucleotide derivatives which are at least partially double stranded and which comprise a 2'5' linked oligonucleotide radical on at last one 3'- end. The invention...
DE10133779A1 Preparation of polynucleotides useful in gene technology involves reacting free 5'-hydroxy group of a oligonucleotide with a hydroxy group  
Preparation of polynucleotides involves: (a) reacting free 5'-hydroxy group of a oligonucleotide with a hydroxy group; (b) optionally oxidizing the product; (c) removing the 3'-hydroxy protecting...
DE10132025A1 Stepwise synthesis of biopolymers, useful e.g. for preparing DNA chips, using synthons containing protecting group that requires photoactivation before cleavage  
Stepwise synthesis of biopolymers (A) using protected synthons (B) where at least one (B) carries a two-stage protecting group (PG). PG is activated in a light-irradiation step and cleaved in a...
DE10128508A1 Verfahren und Nukleinsäuren für die Differenzierung von Prostata-Tumoren  
Die vorliegende Erfindung betrifft chemisch modifizierte genomische Sequenzen, Oligonukleotide und/oder PNA-Oligomere zur Detektion des Cytosin-Methylierungszustandes genomischer DNA sowie ein...
DE10135550A1 Verfahren zum Herstellen von neuen Spinosyn-Derivaten  
The invention relates to a method for producing novel spinosyn derivatives, which are substituted in the C-21 position by a 1-hydroxy-ethyl radical, to novel spinosyn derivatives of this type per...
DE10132308A1 Kombinationspräparat zur Therapie von immunologischen Erkrankungen  
Es wird ein pharmazeutisches Kombinationspräparat zur Behandlung von überschießenden, schädigenden Immunreaktionen sowie degenerative Prozesse beschrieben, das enthält DOLLAR A a) mindestens ein...
DE10131441A1 Eine neue Gruppe von alpha-Amylasen sowie ein Verfahren zur Identifizierung und Gewinnung neuer alpha-Amylasen  
Die vorliegende Erfindung betrifft eine neue Gruppe von alpha-Amylasen, die einem gemeinsamen Sequenzraum angehören, sowie zu diesen alpha-Amylasen hinreichend ähnliche Proteine mit amylolytischer...
DE10121505A1 Verfahren zum Nachweis von Gram-positiven Bakterien  
Die vorliegende Erfindung betrifft ein Verfahren zum Nachweis und/oder zur Identifizierung von Gram-positiven Bakterien mit hohem GC-Gehalt, insbesondere von Mykobakterien. Das Verfahren umfaßt...
DE10228056A1 Generating nucleation centers on nucleic acid, useful for subsequent metallization in nanotechnology, comprises incubation with a metal salt then reduction  
Generating nucleation centers (NC) for selectively heterogeneous growth of metal clusters (MC) on DNA molecules comprises incubating a DNA solution with a metal salt solution, then the combined...
DE10134103A1 New nucleic acid encoding geranylgeranyl-diphosphate synthase, and related cells, useful for preparation of farnesyl-bacteriochlorophyll a, for photodynamic therapy  
Nucleic acid (I) that encodes geranylgeranyl-diphosphate synthase (CrtE) is: (1) an 867 bp sequence , reproduced; (2) an equivalent of (1) within the degeneracy of the genetic code; (3) a sequence...
DE10133372A1 New polynucleotide sequences from Ashbya gossypii, useful for increasing resistance to stress in A. gossypii, particularly for improving production of Vitamin B2  
Polynucleotide (I) that encodes a protein (II) of the stress response and isolatable from Ashbya gossypii. Independent claims are also included for the following: (1) Oligonucleotides (ON) that...
DE20023055U1 Photolithographic exposure unit for e.g. manufacturing DNA chips, scans target areas of biological material selectively with highly-focused flying spot illumination  
Photolithographic exposure unit for manufacturing DNA chips comprising highly-focused light from a source controlled by a deflection- or positioning unit, directing the light spot onto each...
DE10132338A1 Verwendung von 5'-Desoxy-5'-methylthioadenosin in hautkosmetischen Mitteln  
Die vorliegende Erfindung betrifft die Verwendung von 5'-Desoxy-5'-methylthioadenosin in hautkosmetischen Mitteln zur Verbesserung des Hautbildes, derartige Mittel und ein Verfahren zur...
DE10130846A1 Verwendung von Corrinoiden zur Anwendung bei Hauterkrankungen  
The invention relates to the use of the compounds of formula (I), wherein R represents CN, OH, CH3 or H2O, for building up and improving the resistance of the skin. The compounds are particularly...
DE10160666A1 Verfahren zum spezifischen Schnellnachweis von Trinkwasser relevanten Bakterien  
The invention relates to a method for detecting bacteria in drinking water and surface water, especially a method for simultaneous specific detection of bacteria from the Legionella species and...
DE10129888A1 Verfahren zur Herstellung von perbenzylierten 1-O-Glycosiden  
The invention relates to a method for producing perbenzylated 1-O-glycosides of general formula I or the salts thereof. In said formula, Sugar<1> represents a monosaccharide functionalised in the...
DE10129677A1 Preparation of perbenzylated 1-O-glycoside used e.g. as pharmaceutical intermediate, by reacting perbenzylated 1-hydroxy-sugar with alkylating agent in organic solvent then deprotecting  
Preparation of perbenzylated 1-O-glycoside compounds (I) involves reacting a perbenzylated 1-hydroxy-sugar (II) with an alkylating agent (III) in a water-miscible organic solvent in the presence...
DE10129410A1 Verfahren zum spezifischen Schnellnachweis bierschädlicher Bakterien  
The invention relates to a method for the specific fast detection of bacteria which is harmful to beer by in situ-hybridisation. The invention also relates to oligonucleotide probes suitable for...
DE10129256A1 Antivirale Glykokonjugate  
The invention relates to acetyl- or benzoyl-protected bromoalkyl- beta -D-glucosides and glycoconjugates that can be structured by reacting the acetyl- or benzoyl-protected bromoalkyl- beta...