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DE20308345U1 Injection solution, for use in pyrosequencing equipment, comprises a buffer, deoxynucleotide and an alkaline pH which permits longer sequencing  
An injection solution for use in pyrosequencing equipment comprises: (1) a deoxynucleotide; (2) a buffer; and (3) an alkaline pH which permits longer sequencing, is new.
DE10205607A1 New nucleic acid encoding fatty acid elongase, useful for producing polyunsaturated fatty acids as oils, lipids or free fatty acids  
Isolated nucleic acid (I) that encodes a polypeptide (II) able to extend 16 or 18 carbon fatty acids having at least two double bonds by at least 2 carbon atoms, where the fatty acids...
DE10205500A1 Dyeing of hair in intense orange and red-gold to violet shades uses a mixture of a hydrolysate-containing preparation with 1,2,4-trihydroxynaphthalene glycoside (i.e. Lawson) derivative dye carriers, some of which are new  
A composition for dyeing keratinous fibers is obtained by mixing directly before use (A) a dye carrier containing a 1,2,4-trihydroxynaphthalene glycoside (i.e. Lawson) derivative and (B) a...
DE10204843A1 New nucleic acid from Arabidopsis thaliana, useful e.g. for detecting the presence or expression of corresponding genes, involved in metabolism and detoxification  
Nucleic acid (I) for qualitative or quantitative detection of Arabidopsis thaliana genes, or fragments, or derived RNA, comprises one of 275 fully defined sequences given in the specification, or...
DE10204072A1 Neue Verbindungen, die Faktor Xa-Aktivität inhibieren  
The invention relates to the compounds of formula (I) or to the pharmaceutically acceptable salts, solvates, hydrates or pharmaceutically acceptable formulations thereof. The inventive compounds...
DE10204000A1 Sialysierte Kohlenhydrate  
The invention relates to the use of sialic carbohydrates of general formula (I), containing at least one carbohydrate unit of general formula (II) for the immune modulation, immune suppression and...
DE10203999A1 Cycloglycane  
The use of, in particular homopolymeric, cycloglycans with an annular base structure of 2 to 40 monosaccharides in the ring for the prevention of the invasion and infection of mammalian cells by...
DE10201858A1 Separating nucleic acids from a cell lysate, useful for recovering plasmids from bacteria, comprises passing the lysate through a filter material covering the whole inside surface of a holder  
Separating nucleic acids (NA) from other cell components, comprising: (a) lysis and precipitation of lysate components so that NA remains in solution; and (b) filtering the lysate in a separation...
DE10202419A1 Verfahren zur Hemmung der Expression eines durch eine Chromosomen-Aberration entstandenen Zielgens  
The invention relates to a method for increasing the efficiency of an inhibitor of a tyrosine kinase activity in a cell. The tyrosine kinase is encoded by a gene produced by mutation. In order to...
DE10154290A1 Verfahren zum Nachweis Parodontitis und Karies assoziierter Bakterien  
Die vorliegende Erfindung betrifft das Gebiet der Diagnostik von Mikroorganismen, insbesondere den Nachweis von Bakterien, die mit der Erkrankung einer Parodontitis beziehungsweise Karies...
DE10154290B4 A method for detecting periodontal disease and caries-associated bacteria  
A method for detecting periodontal disease or tooth decay associated bacteria by amplification and hybridization, comprising the steps of A) amplifying nucleic acid to fragments from the genome of...
DE10203713A1 New nucleic acid encoding fatty acid elongase, useful for producing polyunsaturated fatty acids as oils, lipids or free fatty acids  
Isolated nucleic acid (I) that encodes a polypeptide (II) able to extend 16 or 18 carbon fatty acids having at least two double bonds by at least 2 carbon atoms, where the fatty acids...
DE10201732A1 New immunogenic preparation, useful for preparing a composition for treating or preventing infections caused by HIV, Hepatitis B or C virus, Rous-Sarcoma virus or Chlamydia pneumoniae  
An immunogenic preparation comprising mature mRNA coding for at least one antigen of a pathogenic agent, is new. An Independent claim is also included for a vaccine comprising the immunogenic...
DE10201354A1 Novel alk(en)yloligoglycoside betaine quaternary ester useful as an emulsifier, hair conditioner and washing softener  
Alk(en)yloligoglycoside betaine quaternary ester (I) free of ethylene- and/or propylene-oxide is new. Alk(en)yloligoglycoside betaine quaternary ester of formula (I) is new; R1O(G)nOCOCR2R3NR4R5R6...
DE10200410A1 New antisense oligonucleotide, useful for treatment of tumors, inhibits translation of mRNA from the pituitary-tumor transforming gene-1  
Antisense oligonucleotide (AON) designed to inhibit translation of PTTG-1 (pituitary-tumor transforming gene-1) mRNA in human cells is new.
DE19948651A1 Nuclear magnetic resonance imaging contrast agent formulations containing perfluoroalkylated paramagnetic and diamagnetic compounds, having high organ specificity, especially for the lymph nodes  
Galenic formulations (A) contain paramagnetic perfluoroalkylated compounds (I) and diamagnetic perfluoroalkylated compounds (II). (II) include new cyclodextrin complexes (B). Galenic formulations...
DE10200386A1 Genetische Sequenz, für die Creatinindeiminase kodiert und deren Verwendung  
Die vorliegende Erfindung betrifft genetische Sequenzen, für die Proteine oder Polypeptide mit Creatinin-Deiminase-Aktivität kodieren. Des weiteren betrifft die Erfindung die Verwendung dieser...
DE10200252A1 Preparation of desclarithromycin from erythromycin, for use as antibiotic intermediate, comprises five stage process via new silylated and/or N-oxide intermediates  
Preparation of desclarithromycin (I) involves: (1) reacting erythromycin A with silylating agent to give silylated derivative (IX); (2) oxidizing to give silylated N-oxide (X); (3) ethylating...
DE10164197A1 Steuerbare Verstärkung der Empfindlichkeit beim Hybridisierungsnachweis  
Die vorliegende Erfindung ist ein Verfahren zur Verstärkung der Empfindlichkeit der Detektion der Hybridisierung von Nukleinsäuren sowie zur Steuerung dieser Verstärkung. Hierfür werden in die...
DE10164147A1 New macrocyclic antibacterials, useful for treating or preventing infections in human or veterinary medicine, also new intermediates  
Antibacterial macrocyclic compounds (I) and their salts, solvates and hydrates are new. Antibacterial macrocyclic compounds of formula (I) and their salts, solvates and hydrates are new. R5 = H,...
DE10163240A1 Verfahren zur Bleiche oberflächenaktiver Verbindungen  
Disclosed is a method for bleaching aqueous alkyl polyglycoside preparations with the aid of peroxygen compounds, characterized in that the bleaching is carried out in the presence of 4-15 %...
DE10162728A1 Neue Alkalische Protease aus Bacillus gibsonii (DSM 14393) und Wasch-und Reinigungsmittel enthaltend diese neue Alkalische Protease  
The invention relates to a novel alkali subtilisin-type protease formed by Bacillus gibsonii (DSM 14393), in addition to sufficiently related proteins and the derivatives thereof. The invention...
DE10161625A1 Verfahren und Nukleinsäuren für die Analyse einer Lungenzell-Zellteilungsstörung  
Die vorliegende Erfindung betrifft die chemisch modifizierte genomische Sequenz von mit Lungen-Zellteilungsstörungen assoziierten Genen, gegen die Sequenz gerichtete Oligonukleotide und/oder...
DE19964220C2 Modified nucleic acid oligomer, useful for sequencing by hybridization, is substituted by redox agent to allow electrical detection of hybridization  
Nucleic acid oligomer (I) modified by a redox-active substance (II) that is oxidizable and reducible selectively at a potential (phi) of 2 to -2 V, relative to the standard hydrogen electrode, is...
DE10163579A1 Process for the oxidation of organic compounds, e.g. for production of esters from ethers, uses a liquid multi-phase ruthenium catalyst system and an oxygen atom donor and is carried out using an aqueous phase of neutral or alkaline pH  
A process for the oxidation of organic compounds using a liquid multi-phase catalyst system comprising at least one ruthenium-containing compound and an oxygen atom donor, is characterized in that...
DE10163514A1 Storage system for nucleic acid samples comprises a polymer matrix and a storage film, with pores/cavities of dimensions to take the samples which are protected and held in a small space  
The storage system for nucleic acid samples has at least one polymer matrix (1), of a material which is porous and/or forms cavities and/or is hydrophilic. The pores/cavities have dimensions...
DE10162730A1 Allele des glk-Gens aus coryneformen Bakterien  
The invention relates to alleles of the glk gene from coryneform bacteria coding for glucokinases, and to processes for the production of L-lysine by fermentation using bacteria containing such...
DE10162729A1 Allele des sigA-Gens aus coryneformen Bakterien  
The invention relates to alleles of the sigA gene from coryneform bacteria which code for sigma factors A and a process for the fermentative preparation of L-lysine using bacteria which contain...
DE10159904A1 Oligonukleotidanordnung, Verfahren zum Nukleotidnachweis sowie Vorrichtung hierfür  
Die vorliegende Erfindung bezieht sich auf eine Oligonukleotidanordnung mit einem Substrat, das mindestens ein Feld aufweist, wobei in dem zumindest einen Feld Oligonukleotide mit feldspezifischer...
DE10142328A1 Verwendung von Fructose-1,6-Bisphosphate Aldolase zum Identifizieren von neuen fungizid wirksamen Substanzen  
Die Erfindung betrifft Nukleinsäuren, die für Polypeptide aus Pilzen mit der biologischen Aktivität von Fructose-1,6-Bisphosphate Aldolasen kodieren, die davon kodierten Polypeptide sowie deren...
DE10160151A1 Inhibiting expression of target gene, useful e.g. for inhibiting oncogenes, by administering double-stranded RNA complementary to the target and having an overhang  
Inhibiting expression of a target gene (I) in a cell by introducing an inhibitory RNA (dsRNA1) having a double-stranded structure of at most 49 consecutive bases, is new. At least part of one...
DE10107186A1 Neue Form des PHGPx-Proteins als diagnostischer Marker bei männlicher Infertilität  
Diese Erfindung betrifft eine neue Form des PHGPx-Proteins, die Spermienkern-Glutathion-Peroxidase (snGPx) sowie Teile hiervon, die eine Rolle bei der Spermatogenese von Säugetieren spielen, sowie...
DE10164501A1 Verfahren und Nukleinsäuren für die Analyse einer Lymphoid-Zellteilungsstörung  
The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for...
DE10158904A1 Verfahren zur Herstellung von linearen DNA Fragmenten für die in vitro Expression von Proteinen  
Die vorliegende Erfindung betrifft ein Verfahren zur Herstellung von linearen DNA-Fragmenten für die in vitro Expression von Proteinen, bei welchem ein lineares DNA-Fragment, welches zur...
DE10158516A1 Verfahren zum Nachweis von Hybridisierungsereignissen in Nukleinsäuren  
Disclosed is a method for detecting target nucleic acid by hybridization, wherein a) hybridization is carried out with at least one probe nucleic acid which is bound with one end to a solid phase,...
DE10148828A1 Modulation der Expression STAT-1-abhängiger Gene  
Die vorliegende Erfindung betrifft Decoy-Oligonukleotide und Antisense-Oligonukleotide mit der Nukleinsäuresequenz gemäß SEQ ID NO:1 bis 43 sowie deren Verwendung als Arzneimittel.
DE10159078A1 Heterocyclyl polymethine dyes, useful for optical marking of protein, nucleic acid, oligomer, DNA, RNA, cell, lipid, saccharide, ligand, receptor, vitamin, nucleotide, polymer or pharmaceuticals, also for receptor-ligand analysis  
Marker dyes, useful for optical marking of e.g. proteins, based on tri-, penta- or hepta-methines are new. Marker dyes, useful for optical marking of e.g. proteins, of formulae (I), (II) and (III)...
DE10156910A1 Antitumoral and antineoplastic medicaments, effective against carcinoma, sarcoma, lymphoma and leukemia, comprise new or known nucleoside-sulfur containing phospholipid derivatives  
Nucleoside-sulfur containing phospholipid derivatives (I), which on adminstration to humans directly or indirectly provide (I) or other antitumoral or antiproliferative active metabolites or their...
DE10156467A1 Träger zur Synthese sowie Verfahren zur Herstellung von Biopolymeren  
Die vorliegende Erfindung betrifft einen Träger zur Synthese von Biopolymeren, seine Verwendung sowie ein Verfahren zur Herstellung der Biopolymere.
DE10154245A1 Gene die für regulatorische Proteine codieren  
Die Erfindung betrifft neue Nukleinsäuremoleküle, deren Verwendung zur Konstruktion von gentechnisch verbesserten Mikroorganismen und Verfahren zur Herstellung von Feinchemikalien, insbesondere...
DE10156352A1 Enzymatische Synthese von Zuckeracrylaten  
The invention relates to a method for the enzymatic synthesis of sugar acrylates, to a method for producing polymer sugar acrylates, to the polymers which can be obtained according to said method,...
DE10155862A1 Produktion von rekombinanten Antikörpern mittels Fusion mit Elastin-ähnlichen Peptiden  
The invention relates to a nucleic acid molecule in which a first DNA sequence coding for a recombinant antibody is fused with a second DNA sequence coding for elastin-like peptides in such a way...
DE10153957A1 Verfahren zur Isolierung von Nukleinsäuren  
The invention relates to a simplified and rapid method for the isolation of nucleic acids, in particular plasmid DNA from E. coli, whereby after alkaline lysis of the sample, the above is...
DE10152598A1 ARL-2-für die Fertilitätskontrolle  
Es wird ein humanes ARL-2 Protein sowie dessen Verwendung für Fertilitätsstörungen, Therapie und Diagnose beschrieben.
DE10154399A1 Verfahren zur Identifizierung von Wirksubstanzen für die Modulation der pip92-vermittelten Apoptose  
The invention concerns methods for identifying active substances involved in the signal cascade of protein pip92-mediated apoptosis, and methods which can be used to identify proteins interacting...
DE10152376A1 New substrates for phospholipase, useful e.g. for diagnosis and drug screening, contain two fluorophores that make a fluorescent energy-transfer pair  
Phospholipase substrates (I) containing two fluorophores are new. Phospholipase substrates of formula (I) are new. A = 1-20C alkylene or alkenylene; B = NH, NHCO, CONH, NHCONH, NHCSNH, oxygen or...
DE10152147A1 Verfahren zum Aufbringen von Nukleosiden und/oder Nukleotiden auf funktionalisierten Oberflächen sowie Verfahren zur Bestimmung von Kopplungsausbeuten bei der Synthese von Nukleotiden  
Die vorliegende Erfindung betrifft ein Verfahren zum Aufbringen von Nukleosiden und/oder Nukleotiden auf funktionalisierten Oberflächen, die mit reaktiven funktionellen Gruppen versehen sind,...
DE10152615A1 Zuckerester  
Vorgeschlagen werden neue Zuckerester, die man erhält, indem man Zuckersäuren in Gegenwart von Lipasen mit Alkoholen verestert.
DE10152017A1 Arrays mit Hairpin-Strukturen  
The invention relates to arrays of nucleic acids immobilized on a carrier, which are present at least partly in the form of secondary structures such as hairpin structures. The invention also...
DE10150677A1 New nucleic acid encoding fungal mitogen-activated protein kinase, useful as target for identifying fungicides for plant protection, is from Fusarium graminearum  
Nucleic acid sequence, encoding a MAP kinase, (I) comprises (a) sequences (S1) or (S2), of 556 and 490 nucleotides, reproduced; (b) a functional equivalent of (a); (c) a fragment of (a); or (d) a...