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DE202017107872U1 cooling composition  
Composition with i) at least one compound of the formula (I)in the form of one of its stereoisomers; and where R1 a phenyl group optionally substituted by one or two C's1-3 Alkyl or alkoxy groups...
DE202011110963U1 Compounds useful as modulators of TRPM8  
Connection with the structure or a salt or solvate thereof.
DE102011000207A1 N-Arylaminomethylenbenzothiophenone as drugs  
The invention relates to N-Arylaminomethylenbenzothiophenone the general formula (I) for use as medicaments for the treatment of cardiovascular diseases, as well as a process for its synthesis.
DE102010006488A1 Thiophene derivatives and to LC media  
The present invention relates to thiophene derivatives, processes and intermediates for their preparation, their use for optical, electro-optical and electronic purposes, in particular in liquid...
DE102009049696A1 New hole conductor material containing compounds useful e.g. as semiconductor material, preferably p-semiconductor in a solar cell, preferably dye photovoltaic cell, ionic liquid, solvent for chemical reaction and heat carriers  
Hole conductor material containing compounds (Q) are new. Hole conductor material containing compounds (Q) of formula ((IL) n-Linker-(HTM) n) (I), ((IL-Linker) p-HTM) (II) or (IL-(Linker-HTM) p)...
DE102007061766A1 New 4-(4-cyano-2-thioaryl)-dihydro-pyrimidinone compounds are human neutrophil elastase inhibitor, useful for the treatment or prevention of e.g. pulmonary arterial hypertonia, acute lung injury and diseases of the cardiovascular system  
4-(4-Cyano-2-thioaryl)-dihydro-pyrimidinone compounds (I) and their salts, solvates and solvates of the salts, are new. 4-(4-Cyano-2-thioaryl)-dihydro-pyrimidinone compounds of formula (I) and...
DE102007044277A1 Substituted nicotinamide compounds and their use in medicaments  
The This invention relates to substituted nicotinamide compounds, Processes for their preparation, pharmaceutical compositions containing these Compounds, and the use of these compounds for the...
DE102007020493A1 Substituted amide derivatives  
The This invention relates to substituted amide derivatives, processes for their preparation, medicaments comprising these compounds, and the use of substituted amide derivatives for the...
DE102007020492A1 Substituted sulfonamide derivatives  
The This invention relates to substituted sulfonamide derivatives, Processes for their preparation, pharmaceutical compositions containing these compounds, and the use of substituted sulfonamide...
DE102006053637B4 Last fluoro-substituted 1,4-Benzothiepin-1,1-dioxide derivatives, pharmaceutical compositions containing them and their use  
Compounds of the formula I, which mean X NH; R1 (C1-C6) Alkyl; R4 F; R4 'H, F; R2, R2 ', R3, R3', R5, R5 'independently of one another H, F, Cl, Br, I, OH, - (CH2) -OH, CH2F, CHF2, CF3, NO2, N3,...
DE102006053637A1 New fluorine-substituted 1,4-benzothiepine-1,1-dioxide, a process for their production, medicaments containing these compounds and their use  
The Invention relates to the compounds of formula I and physiologically acceptable Salts. The compounds are suitable for. B. as hypolipidemic agents.
DE102006053635A1 New substituted with benzyl 1,4-Benzothiepin-1,1-dioxide derivatives, processes for their preparation, pharmaceutical compositions containing them and their use  
The Invention relates to the compounds of formula I and physiologically acceptable Salts. The connection is suitable for. B. as hypolipidemic agents.
DE102006053635B4 New substituted with benzyl 1,4-Benzothiepin-1,1-dioxide derivatives, pharmaceutical compositions containing them and their use  
Compounds of formula and the pharmaceutically acceptable salts thereof.
DE102007037830A1 Indolinsulfonamidverbindungen  
A Number of Indolinsulfonamidverbindungen disclosed. The formula the Indolinsulfonamidverbindungen is shown as formula (I). In formula (I) R1Is H or halogen; is R2 Ar, Ar-C (O) -, Ar-CH2-,...
DE102006033140A1 Aminoindazolharnstoffderivate  
New Aminoindazolharnstoffderivate of the formula I, where R1. R2, R3, R4, R5, X and Y are who in claim 1, is reactedare SGK inhibitors and can for the treatment of SGK-induced diseases and...
DE102006005937A1 New fredericamycin derivatives are topoisomerase I inhibitors useful to treat tumor, parasite, immunosupression and neurodermititis  
Fredericamycin derivatives (I) and their stereoisomers, tautomers and salts are new. Fredericamycin derivatives (I) of formula (Ia) or (Ib) and their stereoisomers, tautomers and salts are new. R1...
DE102005062985A1 New bis-aromatic substituted N-ethyl propiolamide derivatives, useful for treatment and prevention of e.g. pain, anxiety and panic attacks, are inhibitors of the mGluR5 receptor  
Bis-aromatic substituted N-ethyl propiolamide derivatives (I) optionally as pure stereoisomers, particularly enantiomers or diastereomers, including racemates and mixtures in any proportion, also...
DE60125036T2 HYDROXYFORMAMIDIN DERIVATIVES AND DRUGS CONTAINING THE SAME  
Pharmaceutical agents for inhibiting the production of 20-HETE which participates in constriction or dilation of microvessels in major organs such as the kidneys and the cerebral blood vessels, or...
DE102005049953A1 Carbamoylbenzotriazol derivatives as inhibitors of lipases and phospholipases  
The This invention relates to benzotriazole derivatives of the general Formula I with the meanings given in the description, which pharmaceutically acceptable salts and their use as drugs.
DE102005045518A1 New 5-thienylaminocarbonylmethyl-oxazolidin-2-one derivatives, useful for treating and preventing thromboembolic disease, are selective inhibitors of coagulation factor Xa  
3-(4-Aminophenyl)-5-thienylcarbonylaminomethyl-oxazolidin-2- one derivatives (I), and their salts, solvates and solvated salts are new....
DE102005033103A1 Heterocyclylamide-substituted thiazoles, pyrroles and thiophenes  
The Invention relates heterocyclylamide-substituted thiazoles, pyrroles and thiophenes and to processes for their preparation, their use for the treatment and / or prophylaxis of diseases and...
DE102005025989A1 carboxamides  
use carboxamides of the formula (I), in whichA, R1, M, Q and R have the meanings indicated in the description have,for fighting certain rust fungi such as soybean rust and coffee rust, in Plant...
DE102005027274A1 Inhibitors of soluble adenylate cyclase  
The Invention relates to compounds of general formula I as well as their Preparation and use as a medicament.
DE60202452C5 PYRIDAZINONALDOSE REDUCTASE INHIBITORS  
connection of the formula I a prodrug thereof or a pharmaceutically acceptable salt of said compound or prodrug, wherein A represents S, SO or so2 stands; R1 and R2 independently Hydrogen or...
DE102005017301A1 Substituted chroman derivatives, processes for their preparation and their use as anti-inflammatories  
The Invention relates to multi-substituted heterocyclic compounds of the general formula (I), Processes for their preparation and their use as anti-inflammatories.
DE102005014906A1 New pyrimidine compounds e.g. N-((4-ethyl-6((2-(trifluoromethyl) pyridine-4-yl)oxy) pyrimidine-2-yl)methyl) cyclopropane carboxamide useful for combating weeds  
Pyrimidine compounds (I) and their N-oxides and/or salts are new. Pyrimidine compounds of formula (I) and their N-oxides and/or salts are new. Either R 1>, R 2>H, halo, cyano, amino, isocyano, OH,...
DE102005014638A1 Substituted Pyrazolyloxyphenylderivate as herbicides  
It be Pyrazolyloxyphenylderivate the general formula (I) and their use as herbicides. In this general formula (I), R1, R2 and R3 for various Radicals, and A is a cyclic radical from the group...
DE102005008649A1 New substituted pyrrolidinones, their preparation and their use as medicaments  
object the present invention relates to new substituted pyrrolidinones of the general formula wherein A, X, B and R1 to R9 as in claim 1 are as defined, the tautomers, the enantiomers, the...
DE102005028077A1 Alkynyl substituted thiophenes  
The Invention relates to alkynyl substituted thiophenes and processes to their preparation, their use for the treatment and / or prophylaxis of diseases and their use for producing medicaments for...
DE102004063797A1 Oxygenated fused Phenylpiperazin- and Phenyldiazepancarboxamide  
The present invention relates to oxygen-containing fused Phenylpiperazin- and Phenyldiazepancarboxamide the general formula The compounds are useful for suitable medical application.
DE102004061593A1 Substituted N-heterocyclic compounds and their therapeutic use  
The This invention relates to substituted N-heterocyclic compounds of the general formula (I), wherein Ar, A1. X, Y, A2 and Q have the meanings given in Claim 1 have, as well as the tautomers of...
DE102004055998A1 Small-molecule inhibitors of guanine nucleotide exchange factors of Cytohesin family  
The present invention relates to pharmaceutical compositions and their use, wherein the drug compounds are selected from the group comprising the general formulas (1), (2), (3), (4) and / or their...
DE102004023635A1 Heteroaryl-cyclohexyl-1,4-diamine derivatives  
The This invention relates to substituted cyclohexyl-1,4-diamine derivatives, Processes for their preparation, pharmaceutical compositions containing these compounds, and the use of substituted...
DE102004037428A1 New 2-thienylalkylamino-substituted 1,3,5-triazine derivatives, useful as herbicides, particularly for selective use  
2-Thienylalkylamino-1,3,5-triazine derivatives (I) and their salts are new. 2-Thienylalkylamino-1,3,5-triazine derivatives of formula (I) and their salts are new. R1>3-6C cycloalkyl or...
DE102004036552A1 Aminocarbonyl-substituted Thiensulfonylamino (thio) carbonyl-triazolin (ethi) ones  
The Invention relates to novel substituted thien-3-yl-sulfonylamino (thio) carbonyl-triazolin (ethi) ones of the general formula (I), in whichQ1. Q2, R1, R2, R3, R4 and R5 as defined in the...
DE102004036551A1 Dioxazinyl substituted thienylsulfonylaminocarbonyl  
The Invention relates to novel substituted thienylsulfonylaminocarbonyl of the general formula (I), in which R, Het and R3 to R8th in the Description have the meaning given,Processes and...
DE102004036550A1 Aminocarbonyl-substituted Thienylsulfonylharnstoffe  
The Invention relates to novel substituted Thienylsulfonylharnstoffe of the general formula (I), in which A, Q, R1, R2, R3. R4, R5 and R6 as defined in the description have,Processes and...
DE102004031323A1 Substituted Pyridazincarboxamide and derivatives thereof  
The This invention relates to compounds of formula (I), in which the substituents in the description have the meaning given to the use of the compounds as plant treating agents and pesticides as...
DE102004020908A1 Substituted 5,6,7,8-tetrahydro-pyrido [4,3-d] pyrimidin-2-yl and 5,6,7,8-tetrahydro-quinazolin-2-yl compounds  
The This invention relates to substituted 5,6,7,8-tetrahydro-pyrido [4,3-d] pyrimidin-2-yl and 5,6,7,8-tetrahydro-quinazolin-2-yl compounds, processes for their preparation, pharmaceutical...
DE102004018953A1 4-haloalkylpyridine-3-sulfonic acid amides, processes for their preparation, agents containing them and their use as pesticides  
4-halo-alkyl-pyridin-3-sulfonic acid amides, Processes for their preparation, to compositions comprising them and their Use as pesticidessulfonamides of formula (I) and salts thereof, where the...
DE102004017935A1 New alkyne compounds with MCH antagonistic activity and medicaments containing these compounds  
The This invention relates to alkyne compounds of general Formula I, in which the groups and residues A, B, W, X, Y, Z, R1 and R2 the exhibit in claim 1 meanings indicated. further relates the...
DE102004015007A1 Substituted imidazoles  
The Invention relates to substituted imidazoles and methods for their Preparation, their use for the treatment and / or prophylaxis of diseases and their use for producing medicaments for the...
DE102004012901A1 silylated carboxamides  
New silylated Carboxamideder formula (I) in which M, L, R1, R2, R3. R and A have the meanings given in the description,several Methods for preparing these substances and their use for Fight of...
DE102004012070A1 New cycloalkyl-containing 5-Acylindolinone, their preparation and their use as medicaments  
The present invention relates to cycloalkyl-containing 5-Acylindolinone of the general formula in which R1 to R3 are as defined in claims 1 to 6, whose Tautomers, the enantiomers, the...
DE10100772B4 Ether and amide compounds, processes for their preparation and their use as antidiabetic agents  
connection of the general formula (I) R1AR2- (I)where A -O- ormeans; means means (with the proviso that (I) when A is -O-, n is 2 or 3, (Ii) when Ameans then n is 1 or 2; R8th-NHSO2-CH2-,...
DE10359791A1 Substituted thiophenes  
The Invention relates to substituted thiophenes and to processes for their Preparation, their use for the treatment and / or prophylaxis of diseases and their use for producing medicaments for the...
DE102004005317A1 Optically active carboxamides  
New optically active carboxamides of the formula (I), in which R, M and A in the description have the meanings given,several methods for producing these substances and their use for controlling...
DE10346939A1 New arylalkanol derivatives used for treating e.g. respiratory diseases, joint diseases, vascular inflammations, skin disorders, kidney and liver diseases and neurological diseases  
Arylalkanol derivatives (I) are new. Arylalkanol derivatives of formula A-C(R 1>)(R 2>)-CH 2-C(OH)(R 3>)-B'-NH-Q (I) and their isomers and salts are new, except for phthalazinone derivatives. A :...
DE19549755B4 Non-solvated crystalline pharmaceutical - comprises 6-hydroxy-2-(4-hydroxyphenyl)-3- (4-(2-piperidino-ethoxy) benzoyl)-benzo(b)-thiophene hydrochloride  
Non-solvated crystalline 6-hydroxy-2-(4-hydroxyphenyl) -3-(4-(2-piperidino-ethoxy) benzoyl)benzo(b)thiophene (I') hydrochloride with a defined X-ray diffraction pattern obtd. with copper radiation...
DE10346245A1 Verfahren zur Herstellung von Acylharnstoffderivaten, Salze dieser Acylharnstoffderivate und deren Verwendung als Sch√§dlingsbek√§mpfungsmittel  
Ein Verfahren zur Herstellung von Acrylharnstoffderivaten der Formel (I), wobei die Symbole und Indizen die in der Beschreibung angegebenen Bedeutungen haben, bei dem man eine Verbindung der...