Matches 1 - 34 out of 34


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DE202014008232U1 A dual-labeled probe for molecular imaging and its use  
Compound or a pharmaceutically acceptable salt thereof, with a chemical structure comprising: (A) a motif that specifically binds to cell membranes by neoplastic cells, wherein the subject...
DE102010055299A1 Biodegradable contrast agent  
Compositions with a biodegradable contrast agents for magnetic resonance representations (MR), the use of the composition or of the contrast agent for coating medical devices, a method for coating...
DE102010055299B4 The method and mixture for making a medical device  
A method for making a medical device, comprising the steps of a. Preparation of a mixture containing at least an MR contrast agent, at least one organic solvent selected from the group of...
DE102010034496B4 1 - Photosensive molecular switch with a chelate ligand and isomerizable photochromic system  
A photosensitive molecular switch, comprising - a chelate ligand, - a metal ion coordinately attached to the chelate ligand, wherein the metal ion is selected from the group of metal ions...
DE102010034496A1 Photosensiver molecular switch with a chelate ligand and isomerizable photochromic system  
Photosensitive molecular switch, with a chelate ligand, a coordinated on chelating ligand bound metal ion, wherein the metal is selected from the group of metal ions consisting of Mn2+, Mn3+,...
DE102010008417A1 High-affinity multivalent chelator compounds (MCH) and their use for structural and functional analysis of target molecules  
The present invention relates generally to multivalent chelator compounds (MCHs) having three or four nitrilotriacetic acid (NTA) groups as chelator groups and in a first aspect a free thiol...
DE102007058220A1 New metal complexes useful e.g. for manufacturing agent for X-ray diagnostics and magnetic resonance tomography-diagnostics of brain infarcts and liver tumor, and/or space-process in liver and abdomen tumors and musculoskeletal tumors  
Metal complexes (A) are new. Metal complexes (A) of formula (Ia), (Ib) or (Ic) are new. Hal : Br or I; A 1>-CONR 1>-(CH 2) n-NR 2>-(CO-CHZ 1>-NH) m-CO-CHZ 2>-K 1>or -CONR 1>-(CH 2) p-(CONR 2>CH 2)...
DE102007041836A1 Method for imaging a prostate tumor and for suitable contrast agent  
The Invention relates to a method for imaging of a prostate tumor (1), in which the patient over a the bloodstream distributable contrast agent is supplied to the at least one includes type of...
DE112007001058T5 Electrically variable transmission having a plurality of connected gear sets  
electric variable transmission comprising: an input member for Receiving power from an engine; an output member; a first and second motor / generators; a first, second and third differential gear...
DE102007034956A1 A method for detecting a neuro pathologic brain region  
The The present invention relates to a method (100) for detecting a neuropathological changes Gehinregion (10) the following steps:- Administering (102) a radiolabeled Substance (12), the modified...
DE102006049821A1 New, well tolerated metal chelates, for use as radiodiagnostic, radiotherapeutic or NMR and X-ray diagnostic agents, contain chelator and perfluorinated polyethylene glycol residues  
New metal chelates (I) (optionally in salt form) contain (a) perfluorinated polyethylene glycol (PEG) residue(s), (b) chelator residue(s) and (c) at least one equivalent of metal(s) of atomic...
DE102007027689A1 Contrast improving agent from an aqueous solution useful for a fluorescence coloring of the lumen of the digestive tract through intravenously obtained fluorescence dye  
Contrast improving agent, for a fluorescence coloring of the lumen of the digestive tract through intravenously obtained fluorescence dye, from an aqueous solution with a buffer capacity and a pH...
DE102006021495A1 Use of metal chelate containing perfluorinated alkyl-residue, chelator-residue and metal ion equivalent to the atomic number, for the production of diagnostic agent for representation of amyloid-containing plaques  
Use of metal chelate containing at least a perfluorinated alkyl-residue; at least a chelator-residue; and at least a metal ion equivalent to the atomic number 21-29, 31-33, 37-39, 42-44, 49 or...
DE10361140B4 A process for the preparation of dendritic Trimesinsäuretriamiden, Diethylentriaminderivate used therein and using the Diethylentriaminderivate  
process for the preparation of compounds of the general formula I wherein R represents a Z or a Boc protecting group stands wherein in non-protic solvents, using an acid scavenger Temperatures of...
DE102005019452A1 New 18-fluorine-substituted 3'-deoxythymidine derivatives, useful in positron emission tomography, particularly for detection of brain tumors  
18-Fluorine-substituted 3'-deoxythymidine derivatives (I) are new. 18-Fluorine-substituted 3'-deoxythymidine derivatives of formula (I) are new. X : hydrogen or 18-fluoro; Y : hydrogen, azido or...
DE10231799B4 Use of perfluoroalkyl-metal complexes as contrast agents in MR imaging for representing intravascular thrombi  
use of perfluoroalkyl-metal complexes that a critical micelle concentration <10-3 minor, a hydrodynamic micelle diameter> 1 nm and a proton relaxivity in plasma> 10 l / mmol · s, as contrast...
DE10040380B4 MRI contrast agent for visualization of plaque, lymph nodes, infarcted and necrotic tissue or both necrosis and tumors, comprising perfluoroalkylated metal complex having specific micelle forming properties  
Use of perfluoroalkylated metal complexes (I), having a critical micelle formation concentration of less than 1 mM, a hydrodynamic micelle diameter of more than 1 nm and a proton relaxivity in...
DE102004062258B3 New hydroxypyrimidone, hydroxypyridinone or dihydroxybenzene derivatives useful for preparing conjugates of biomolecules useful as magnetic resonance contrast agents  
Hydroxypyrimidone, hydroxypyridinone or dihydroxybenzene derivatives (I) are new. Hydroxypyrimidone, hydroxypyridinone or dihydroxybenzene derivatives of formula (I) and their salts are new:...
DE102004026103A1 Trimers macrocyclic substituted aminoisophthalic halogen benzene derivatives  
The Metal complexes of general formula I, wherein Hal is bromine or Iodo, and A1 and A2 different have the meaning, are useful as contrast agents.
DE19964224B4 Pharmaceutical preparations containing calcium complex of tetrahydrogen (MS-325) and salts thereof as well as methods for preparing the compositions  
pharmaceutical Means comprising at least one calcium complex of [[(4R) -4- [bis [(carboxy-.kappa.O) methyl] amino-.kappa.N] -6,9-bis [( carboxy-.kappa.O) methyl] -1 - [(4,4-...
DE10305462A1 Conjugates of enantiomerically pure (4S, 8S) - and (4R, 8R) -4-p-benzyl-8-methyl-3,6,9-triaza-3N, 6N, 9N tricarboxymethyl-1,11-undecanedioic acid with biomolecules, method to their preparation and use for the preparation of  
The invention relates to enantiomerically pure conjugates of the formulas VIIa and VIIb, wherein A represents a group -COO-, and Z and R have different meanings, and their use.
DE19646762B4 Use of metal compounds for the preparation of agents for radiotherapy of tumors  
Use of metal compounds for the preparation of agents for radiotherapy of tumors, characterized in that the metal compound contains a metal ion of atomic numbers 20-32, 39-51 or 57-83 and a...
DE10231799A1 Use of perfluoroalkyl-metal complexes as contrast agents in MR imaging for representing intravascular thrombi  
The invention relates to the use of perfluoroalkyl-containing metal complexes that a critical micelle concentration <10-3 mol / l, a hydrodynamic micelle diameter (2 Rh)> 1 nm and a proton...
DE10222481A1 Contrast agents for use in imaging procedures  
A contrast agent for use in imaging processes is claimed which contains superparamagnetic particles and a tissue-specific substance which is selected from diphosphonic acids and their...
DE10209018C1 Perfluoroalkyl Trijodaromaten micelle-forming, processes for their preparation and their use as contrast agents containing them as well as diagnostic agents  
The invention relates to novel perfluoroalkyl Trijodaromaten, to processes for their preparation, their use as contrast agents for X-ray diagnostics, and for magnetic resonance diagnosis and...
DE10064467A1 Lithium complexes of N- (1-hydroxymethyl-2,3-dihydroxypropyl) -1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane, their production and use  
The invention relates to crystalline lithium complexes of N- (1-hydroxymethyl-2,3-dihydroxypropyl) -1,4,7-triscarboxymethyl-1,4,7,10 tetraazacyclododecane, their production and the recovery of the...
DE10117242C1 New dimeric tetraazacyclododecane derivatives and their metal complexes useful as components of diagnostic agents, especially X-ray contrast agents, and radiotherapeutics  
Asymmetrically bridged dimeric tetraazacyclododecane derivatives (I) and their metal complexes are new. Asymmetrically bridged dimeric tetraazacyclododecane derivatives of formula (I) and their...
DE10040858A1 Perfluoroalkyl-containing complexes with polar radicals, process for their preparation and their use  
Perfluoroalkyl-containing complexes with polar radicals of general formula I DOLLAR F1 wherein R represents the polar radical, R¶f¶ means a perfluorinated carbon chain, K is a metal complex and Z...
DE10066210B4 Use of perfluoroalkyl-metal complexes as contrast agents in MR imaging for displaying plaques  
use of perfluoroalkyl-metal complexes that a critical micelle concentration <10-3 minor, a hydrodynamic micelle diameter> 1 nm and a proton relaxivity in plasma> 10 l / mmol · s, as contrast...
DE10040380A1 MRI contrast agent for visualization of plaque, lymph nodes, infarcted and necrotic tissue or both necrosis and tumors, comprising perfluoroalkylated metal complex having specific micelle forming properties  
The invention relates to the use of metal complexes containing perfluoroalkyl, comprising a critical micelle formation concentration < 10<-3> mol/l, a hydrodynamic micelle dynameter of (2 Rh) > 1...
DE3448606C2 Diagnostic agents, to processes for their preparation and their use  
Claimed are a diagnostic agent for use in in vivo NMR diagnosis, comprising at least one physiologically compatible complex salt of the anion of a complexing acid and one or more central ion (s)...
DE10002939C1 New aromatic-substituted tetraazacyclododecane-triacetic acid paramagnetic metal complex compounds, are useful as contrast agents for magnetic resonance imaging of necrotic or infarction tissue  
Polycyclic aromatic-substituted 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid metal complex derivatives (I) are new. Polycyclic aromatic-substituted...
DE10013849A1 L-selectin contrast agent  
The invention relates to novel contrast agents for depicting changes in lymph nodes, depicting inflammatory processes, and pathological changes. The inventive contrast agents are bound to the...
DE19603033A1 Perfluoroalkyl-containing metal complexes, processes for their preparation and their use in NMR diagnosis  
The invention concerns new monomer perfluoroalkyl-substituted metal complexes, a process for their production, and their use in diagnostics and therapy. The compounds according to the invention to...

Matches 1 - 34 out of 34