Matches 1 - 47 out of 47


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DE102013105144A1 The pharmaceutical combination product with an anti-idiotype antibody fragment  
The invention relates to a pharmaceutical combination preparation (10), in particular to suppression of an immune response, preferably a humoral immune response against a therapeutic organism...
DE102006053385B4 Enterococcus faecalis antigen  
Enterococcus faecalis strain type 5 antigen, at least one disaccharide unit comprising, having the following formula: where R1 OH, X = O, Y = O and CA lactyl is.
DE10351627B4 Modulation of angiogenesis by Bartonella henselae  
Use of a peptide comprising a fragment of Bartonella henselae adhesin protein A (BadA) for the manufacture of a medicament for the modulation of angiogenesis.
DE102008010727A1 Bacterial O-antigen based active immunization, useful e.g. to promote formation of O-antigen-sensitive antibodies, comprises parenteral administration of O-antigen saccharide from e.g. Escherichia coli pathotypes in a suspension  
Bacterial O-antigen based active immunization comprises parenteral administration of extracted and purified O-antigen saccharide from potential pathogenic enterobacteria, which is cultured under...
DE102007044673A1 Vaccine for the treatment of celiac disease and method of producing the vaccine, Use of a conjugated with a bacterial toxin peptide sequence for activating the immune system against prolamines and Designer peptide  
vaccine for the treatment of celiac disease, which as an active ingredient at least one with a part a bacterial toxin conjugate, consisting of at least 4 amino acids unbranched toxic peptide...
DE102007012824A1 Vaccine strains with graded colony size/attenuation comprise at least two attenuating metabolic drift mutations that are resistance mutations  
Vaccine strains with graded colony size/attenuation comprise at least two attenuating metabolic drift mutations that are resistance mutations, preferably to antibiotics or toxic substances. An...
DE60130743T2 MICRO BALLS FOR ACTIVE EMBOLIZATION  
The present invention relates to injectable compositions comprising biocompatible, swellable, substantially hydrophilic, non-toxic and substantially spherical polymeric material carriers which are...
DE102006053385A1 Enterococcus faecalis and / or Enterococcus faecium antigen  
The This invention relates generally to the field of detection and prevention of infectious diseases caused by Enterococcus faecalis and / or Enterococcus faecium caused. In particular relates to...
DE102005024836A1 Composition for treatment and prevention of bone tumors and metastases to bone, comprises microorganisms that carry a gene for abnormal bone sialoprotein, inducing an immune response  
Composition (A) for treatment and prevention of bone tumors and metastases that preferentially colonize bone tissue comprises as active agent killed or weakly pathogenic microorganisms that...
DE102005010288A1 Pharmaceutical, orally administrable preparation for the treatment of fish, manufacturing process for this and its use  
The Invention relates to a pharmaceutical, orally administrable preparation for Treatment of fish, in particular for the oral immunization of Salmonids. The preparation contains (1) at least one...
DE102004046391A1 New vaccine for veterinary and human medical prophylaxis and therapy  
The This invention relates to a new vaccine, its use for immunoprophylaxis and / or treatment of candida in human and veterinary and process for its production, wherein the vaccine from the...
DE102004024674A1 Means and methods for diagnosis, prophylaxis and treatment of connective tissue diseases  
The present invention provides compositions comprising at least a binding to a pathogen associated molecular patterns (PAMP) receptor capable Substance; and at least one trihelikales fiber...
DE10351627A1 Modulation of angiogenesis by Bartonella henselae  
The This invention relates to the use of Bartonella henselae for the manufacture of a medicament for the modulation of angiogenesis; a nucleic acid molecule which from the gene encoding the...
DE4139840B4 Antigen preparation for the detection of H. pylori  
Composition, containing derived from Helicobacter pylori proteins to Detecting the presence of Helicobacter pylori antibodies used are characterized by the following features: - The composition...
DE202004017198U1 System for storing liquid additives, for use in animal husbandry or fish farming, comprises wall-mounted holder, into which containers of liquid fit, each container being fitted with hose for emptying  
The system for storing liquid additives, for use in animal husbandry or fish farming, comprises a wall-mounted holder (1), into which containers (2) of liquid fit. Each container is fitted with a...
DE10326187A1 Cells as a carrier for bacteria  
The Invention relates to the use of a cell with a a foreign DNA-containing microorganism, particularly bacterial Microorganism is loaded, for preparing a pharmaceutical Composition, wherein the...
DE10210529A1 Vaccine for treating or preventing infection by human immune deficiency virus, comprises anti-toxins, plant-derived amino acids, Weig'l vaccine and hydroxybutyric acid  
Vaccine for treating AIDS and for preventing HIV infection comprises antitoxin (Behring); amino acids from Hypericum perforatum and Bryonia album; Weig'l vaccine; hydroxybutyric acid and water.
DE10116042A1 Exotoxin ligand  
The present invention relates to a ligand for bacterial toxins, particularly entero- or exotoxin of gram-positive bacteria, which is capable of selective interaction with a structure comprising an...
DE10126367A1 Pharmaceutical composition comprises Borrelia antigens and encoding nucleic acid, useful for diagnosis, treatment and prevention of Lyme borreliosis  
Pharmaceutical composition comprising at least one of: (a) a polypeptide (I) comprising fully defined sequences of 251, 212, 217 or 219 amino acids as given in the specification or the...
DE10115276A1 Preparation of vaccine against Salmonella, useful for protecting poultry, by inactivating enterotoxins and cytotoxins from the serovar 'Weltevreden'  
Preparation of a vaccine (I) from enterotoxins and cytotoxins (A), isolated from Salmonella spp., comprises treating (A) with formalin at a predetermined ratio, concentrating the resulting toxoid...
DE10012370A1 Use of oil-in-water emulsion as vaccine adjuvant, particularly for influenza and pneumococcal vaccines, administered at different site from the vaccine  
Use of an oil-in-water emulsion (A) as an adjuvant for vaccines, by contralateral application, where (A) comprises about 5% squalene, 0.5% Polysorbate 80 and 0.5% sorbitan trioleate in aqueous...
DE19963840A1 A composition for preventing and treating allergic diseases  
The invention relates to a composition comprising at least one airborne transferable microbial antigen that typically occurs in the stable air, the use of this composition for preventing and...
DE10007771A1 Immunomodulatory effective compositions, processes for their preparation and their use  
The invention relates to immunomodulatory effective microbiological compositions, to methods for the production thereof and to their use. The inventive microbiological immunomodulators are suited...
DE10003241A1 Closing bacterial ghosts  
The invention relates to a method for production of closed bacterial ghosts, by means of vesicle membrane fusion and the corresponding bacterial ghosts. Active agents, for example, genetic...
DE19963859A1 Bi- or oligomer of a di-, tri-, Quattro or pentamer of recombinant fusion proteins  
The invention relates to oligomers of a dimer, trimer, quatromer or pentamer of recombinant fusion proteins. Said oligomers are characterised in that the recombinant fusion proteins have at least...
DE19851282A1 Composition a pharmaceutically active substance, applied in a specific delivery system for the prevention and treatment of infectious diseases  
The present invention relates to an improved pharmaceutical substance in addition to an improved dispensing device that allows for more effective nasal administration of a substance.
DE19847142A1 Diagnosing borelliosis by detecting specific antibodies, using new Borellia antigens expressed preferentially during infection and also useful as immunogens in vaccines  
Diagnosis of borelliosis by detecting anti-Borellia antibodies (Ab) using a detection reagent (A) that contains many Borrelia antigens (Ag). Ag: (i) react with anti-Borellia immune serum from...
DE19847628A1 Outer membrane protein of Helicobacter pylori and DNA sequences, useful in vaccines and for production of diagnostic or therapeutic antibodies  
An outer membrane protein (I) from Helicobacter pylori, a fragment of (I) or a protein (II) with the same immunogenic characteristics, is new. Independent claims are also included for the...
DE19633698A1 New systems for the regulation of gene expression  
The present invention concerns a process for selecting new PR- or PL-operator sequences of lambdoid phages which, compared to wild-type sequences, have a different thermostability for the binding...
DE19630390A1 Proteins, especially membrane proteins of Helicobacter pylori, their preparation and use  
The present invention relates to novel proteins, in particular membrane proteins or proteins which are firmly associated with the membrane, which are derived from Helicobacter pylori (H. pylori)...
DE19626614A1 Complex of antigen and cell constituent, a vaccine composition containing the complex, pharmaceutical preparation, and methods for preparing the complex  
The invention relates to a complex comprising an antigen of a microbial or molecular pathogen and mammalian cell constituents in isolated or purified form. A vaccine composition containing the...
DE19603649A1 Recombinant expression of S-layer proteins  
The invention concerns processess for the recombinant preparation of S-layer proteins in gram-negative host cells. In addition, the nucleotide sequence of a new S-layer gene and a process for...
DE19627392A1 Drug for administration through the nose  
Vaccines or pharmacologically active peptides are compounded with ion-exchange resin particles with a mean particle size of less than 200 M and may be in the form of powders or suspensions for...
DE19521705A1 An immunogenic construct, to processes for its preparation and use as a vaccine  
The invention concerns an immunogenic construct comprising as components (i) an inactive flavivirus or a derivative thereof, and (ii) at least one immunogenic component which is bonded to the...
DE4425382A1 Rapid detection of live bacterial vaccine  
A method for the diagnostic detection of live bacterial vaccines in human or veterinary medicine involves genetically labelling a bacterial strain suitable for use as live vaccine with luciferase...
DE19523554A1 Helicobacter pylori vaccines and therapeutic compositions  
A H.pylori (Campylobacter pylori) protein, designated HAP (haemagglutinin/protease) is described as a suitable subject for a peptide/protein vaccine or therapeutic composition to prevent against...
DE4419294A1 Legionella pneumophila DNA coding for major outer membrane protein  
The following are claimed: (a) a nucleic acid sequence which is a defined sequence of 907 bp given in the specification and represents the complete open reading frame coding for the 29 kD major...
DE4401419C1 Secretion of proteins of the outer membrane of Gram-negative bacteria by means of Gram-positive host organisms  
The invention relates to a process for producing outer membrane proteins of gram-negative bacteria by gram-positive host cells. To this end, a gene structure containing a gene coded for an outer...
DE4221840A1 Bivalent Lebendvakazine against bacterial enteric pathogens, production methods and plasmids and strains as starting material  
A bivalent S. typhi living vaccine is disclosed. The micro-organism contained in this vaccine is capable of expressing a complete LPS with a S.-typhi core and heterologous O-polysaccharides. The...
DE4041351A1 Test antigen for diagnosis of legionellosis and listeriosis - comprises soluble cell components of Legionella, Listeria or Brochothrix  
A test antigen for intracutaneous use in medical and veterinary diagnoses enables legionellosis and listeriosis to be diagnosed. The test antigen pref. comprises the cell components prepd. (a)...
DE4041045A1 TWO-PHASE SYSTEMS FOR THE PRODUCTION AND PRESENTATION OF FOREIGN ANTIGEN IN HYBRIDS LIVE VACCINES  
The present invention relates to a genetic engineering process for the optimal production and exposure to the immune system of additional antigen coded for by a live vaccine. The genetic...
DE4139840A1 Compsns. contg. antigen from cell-associated protein of H. pylorus - useful for sensitive selective detection of antibodies with less false positives and negatives  
Compsn. contains purified antigens (Ag) from the cell associated proteins (I) of Heliobacter pylori, which (a) have mol. wt. below 0.2 million (as measured by reduced Na...
DE4122906A1 Divested bacteria prepn. for vaccines - by binding partially oxidised polysaccharide to surface, and coating modified bacteria with viral or bacterial protein or polypeptide  
Prodn. of vaccines against viral or bacterial antigens or epitopes comprises (1) binding partially oxidised polysaccharides (A) to the surface of bacteria; (2) coating the modified bacteria with...
DE4023721A1 Modified Gram negative bacteria for use as vaccine and adjuvant - are transformed to express lytic protein or toxin, forming ghost(s) which present many cell wall epitope(s)  
Modified bacteria, obtd. by (1) transforming a Gram negative bacterium with (a) the gene of a lytic membrane protein of a bacteriophage, (b) a lytic toxin-release gene or (c) their partial...
DE4039747A1 Polysaccharide vaccine adjuvant contg. aminoalkyl oxy functional gps. - for vaccines readily administered, useful in human and veterinary medicine  
Adjuvant contains a polysaccharide deriv. (I) with functional gps. of formula -O-R1-N(R2)(R3). R1 = -CH2- or -(CH2)2-, R2, R3 = independently H, CH3 or C2H5. The vaccines are prepd. by coating...
DE3942728C1 New immunologically active proteins derived from Borelia burgdorferiensity polyethylene vessel and a high density polyethylene sealing cap - useful as vaccine and for quick accurate diagnosis of Borelia infections  
New pure immunologically active proteins derived from Borrelia burgdorferei are claimed. The proteins are produced from DNA isolated from Borrelia burgdoreferei (DSM No.5662). They can have...
DE3926206A1 Whooping cough vaccine prodn. - using itaconic acid to inactivate microorganisms  
Prodn. of whooping cough vaccines is effected by culturing Bordetella pertussis, inactivating the microorganisms by incubation with 3.75-13 mg/ml of itaconic acid at pH 3.7-4.2 for 1-4 hr.,...

Matches 1 - 47 out of 47