BIPHENYL DERIVATIVES AND THE USE THEREOF AS INTEGRIN INHIBITORS
Kind Code:
A1
Abstract not available for EP1311484
Abstract of corresponding document: US2003187289
Novel biphenyl derivatives of the general formula (I), in which Y, R R<1>, R<2>, R<3>, R<4>, m, o and p are as defined in claim 1, and their physiologically acceptable salts and solvates are integrin inhibitors and can be employed for combating thrombosis, cardiac infarction, coronary heart disease, arteriosclerosis, inflammation, tumours, osteoporosis, infections aid restenosis after angioplasty or in pathological processes which are maintained or propagated by angiogenesis.
Abstract of corresponding document: US2003187289
Novel biphenyl derivatives of the general formula (I), in which Y, R R<1>, R<2>, R<3>, R<4>, m, o and p are as defined in claim 1, and their physiologically acceptable salts and solvates are integrin inhibitors and can be employed for combating thrombosis, cardiac infarction, coronary heart disease, arteriosclerosis, inflammation, tumours, osteoporosis, infections aid restenosis after angioplasty or in pathological processes which are maintained or propagated by angiogenesis.
Inventors:
Staehle, Wolfgang (DE)
Goodman, Simon (DE)
Goodman, Simon (DE)
Application Number:
EP20010969486
Publication Date:
05/21/2003
Filing Date:
07/24/2001
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Export Citation:
Assignee:
MERCK PATENT GMBH (DE)
International Classes:
A61K31/44; A61K31/44; A61K31/4402; A61K31/4402; A61P7/00; A61P7/02; A61P9/00; A61P9/00; A61P9/10; A61P19/00; A61P19/10; A61P27/00; A61P27/02; A61P29/00; A61P29/00; A61P31/00; A61P31/00; A61P35/00; A61P35/00; A61P43/00; A61P43/00; C07D213/00; C07D213/73; C07D213/74; (IPC1-7): C07D213/74; A61K31/44; A61K31/4402; A61P9/00; A61P35/00; C07D213/73
European Classes:
C07D213/73B; C07D213/74D4
Other References:
See references of WO 0216323A1