Title:
PROCESSES FOR THE PREPARATION OF SUMATRIPTAN AND RELATED COMPOUNDS
Kind Code:
A1
Abstract:
Abstract not available for EP1226116
Abstract of corresponding document: WO0134561
The present invention relates to a process for preparing phenylhydrazines of formula (I) in which R represents CH2SO2NHCH3, CH2CH2SO2Ph, CH2CH2SO2NHMe or a group of structure (A), (B), (C), in which a diazonium salt of formula (II) in which X represents an anion derived from hydrochloric acid, sulphuric acid, acetic acid, phosphoric acid, tetrafluoroboric acid or hydrobromic acid is reduced by a dithionite salt. The resulting phenylhydrazines can be converted to the corresponding indole derivatives by the Fischer indole synthesis.
Abstract of corresponding document: WO0134561
The present invention relates to a process for preparing phenylhydrazines of formula (I) in which R represents CH2SO2NHCH3, CH2CH2SO2Ph, CH2CH2SO2NHMe or a group of structure (A), (B), (C), in which a diazonium salt of formula (II) in which X represents an anion derived from hydrochloric acid, sulphuric acid, acetic acid, phosphoric acid, tetrafluoroboric acid or hydrobromic acid is reduced by a dithionite salt. The resulting phenylhydrazines can be converted to the corresponding indole derivatives by the Fischer indole synthesis.
Inventors:
Holman, Nicholas John (GB)
Friend, Christopher Lyndon (GB)
Friend, Christopher Lyndon (GB)
Application Number:
EP20000972875
Publication Date:
07/31/2002
Filing Date:
10/27/2000
View Patent Images:
Export Citation:
Assignee:
BASF AG (DE)
International Classes:
C07D249/00; C07D249/08; C07C303/00; C07C303/40; C07C311/00; C07C311/35; C07D209/00; C07D209/14; C07D209/16; C07D263/00; C07D263/20; C07D295/00; C07D295/20; C07D401/00; C07D401/06; C07D403/00; C07D403/04; C07D403/14; C07D413/00; C07D413/14; (IPC1-7): C07C303/40; C07C311/35; C07D209/14
European Classes:
C07C303/40; C07D209/14
Other References:
See references of WO 0134561A1