MOLECULES THAT HOME TO A SELECTED ORGAN OR TISSUE IN VIVO AND METHODS OF IDENTIFYING SAME
Kind Code:
A1
Abstract not available for EP0876611
Abstract of corresponding document: EP0773441
The present invention provides an in vivo method for identifying molecules that home to a selected organ or tissue. In addition, the invention provides peptides that home to a selected organ or tissue. For example, the invention provides peptides that selectively home to an organ such as brain or kidney or to a tissue such as a tumor tissue. The invention further provides methods of using an organ homing molecule, for example, to target an agent such as a drug to a selected organ or to identify the target molecule expressed by the selected organ.
Abstract of corresponding document: EP0773441
The present invention provides an in vivo method for identifying molecules that home to a selected organ or tissue. In addition, the invention provides peptides that home to a selected organ or tissue. For example, the invention provides peptides that selectively home to an organ such as brain or kidney or to a tissue such as a tumor tissue. The invention further provides methods of using an organ homing molecule, for example, to target an agent such as a drug to a selected organ or to identify the target molecule expressed by the selected organ.
Inventors:
Ruoslahti, Erkki (US)
Pasqualini, Renata (US)
Pasqualini, Renata (US)
Application Number:
EP19960930824
Publication Date:
11/11/1998
Filing Date:
09/10/1996
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Export Citation:
Assignee:
Jolla, Cancer Res Found (US)
International Classes:
A61K9/127; A61K9/127; A61K45/00; A61K45/00; A61K47/42; A61K47/42; A61K47/48; A61K47/48; A61P35/00; A61P35/00; C07K1/00; C07K1/04; C07K1/13; C07K1/14; C07K5/00; C07K5/10; C07K7/00; C07K7/06; C07K7/08; C07K14/435; C07K14/47; C12N15/09; C12N15/09; G01N33/53; G01N33/53; G01N33/566; G01N33/566; G01N33/567; G01N33/567; (IPC1-7): G01N33/567; A61K47/48; C07K1/04; G01N33/50
European Classes:
A61K47/48R2H; C07K1/04C; G01N33/567
Other References:
See references of WO 9710507A1