Matches 251 - 300 out of 300 < 1 2 3 4 5 6
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6184434 Steinernema sp. nematode for suppression of Helicoverpa zea and Spodoptera frugiperda  
A novel entomopathogenic nematode of the genus Steinernema, which is effective as a biopesticide for the control of insects, and particularly the corn earworm, Helicoverpa zea, and the fall...
6184436 Transgenic mice expressing HIV-1 in immune cells  
The present invention relates to a transgenic mouse to serve as a small animal model of AIDS which comprises at least a DNA sequence coding for HIV-1 nef or a HIV-1 DNA genome essentially...
6180849 Trangenic mice with a disruption in the tiar gene  
The invention features transgenic non-human mammals containing a mutation in one or both alleles of the endogenous TIAR gene, and cell lines derived from some of these mammals. The mammals and cell...
6177610 Major basic protein deficient animals  
Major basic protein deficient non-human mammals that contain an inactivated major basic protein allele are described. A nucleic acid construct including an inactivated major basic protein gene is...
6162963 Generation of Xenogenetic antibodies  
The subject invention provides non-human mammalian hosts characterized by inactivated endogenous Ig loci and functional human Ig loci for response to an immunogen to produce human antibodies or...
6156569 Prolonged culturing of avian primordial germ cells (PGCs) using specific growth factors, use thereof to produce chimeric avians  
A culture system for maintaining avian PGCs for long periods in tissue culture is provided. This culture system uses LIF, bFGF, IGF and SCF. The resultant PGCs are useful for the production of...
6147276 Quiescent cell populations for nuclear transfer in the production of non-human mammals and non-human mammalian embryos  
A method of reconstituting a mammalian embryo involves transferring the nucleus from a quiescent donor cell into a suitable recipient cell. The donor cell is quiescent, in that it is caused to exit...
6143564 Use of the polar body chromosomes for the production of embryos and normal offspring  
The invention provides a method for obtaining a live offspring having maternal chromosomes derived from a live first polar body of an oocyte that has completed the first meiotic division. It has...
6140552 Production of recombinant polypeptides by bovine species and transgenic methods  
Transgenes for producing recombinant polypeptides transgenic bovine species. A transgene for producing recombinant polypeptides in the milk of transgenic bovine species comprises at least one...
6136040 Animal model with disrupted FGF-9 gene  
A unique animal model is disclosed which is useful for studying the role of FGF-9 activity in cardiovascular diseases. To provide this animal model, the FGF-9 gene is disrupted in mice, that is,...
6133502 Monocyte chemoattractant protein and its receptor transgenic animal  
Provided is a non-human animal in which an exogeneous gene, a mutant gene thereof of a monocyte chemoattractant protein and/or a receptor thereof is introduced. The present transgenic animals can...
6130365 Breeding lines of color-sexable day-old chicks and methods for producing the same  
This invention relates to a method of producing a novel male parent line and a female parent line of meat-type chickens that are complementary to each other genetically so that upon mating the...
6118044 Transgenic animal allergy models and methods for their use  
Transgenic mice which constitutively express an antibody-type molecule encoded by the transgene and which has an IgE heavy chain constant region and is specific for a pre-defined antigen, provide...
6096876 1-α-hydroxylase materials and methods  
The invention is directed to polynucleotides encoding all or a fragment of the P450 moiety of vitamin D1 α-Hydrdoxylase and polypeptides encoded thereby. It encompasses antibodies to the...
6093872 Extended human hematopoiesis in a heterologous host  
A human hematopoietic system is provided in an immunocompromised mammalian host, where the hematopoietic system is functional for extended periods of time. Particularly, human fetal liver tissue...
6071689 System for improving yield of sexed embryos in mammals  
Improved insemination systems particularly adapted to use for sex-selected sperm sorting include systems which achieve superovulation and then multiple embryo production with sexed embryos. These...
6069297 Glucose-6-phosphate dehydrogenase deficient mice and methods of using same  
Mice which produce measurable levels of glucose-6-phosphate dehydrogenase (G6PD) deficient red blood cells can be used as animal models to evaluate new drugs for risk of inducing hemolytic anemia...
6058878 Protozoan free colonies of lepidoptera  
A method for the establishment and maintenance of colonies of Lepidoptera which are free of contamination with protozoa is provided. The colonies consists of individuals capable of breeding and...
6060643 Mouse model with human immune system  
The present invention provides a non-human genetically immunodeficient mammal the peripheral blood of which contains a non-lethal percent of T-cells of human origin which is at least 20% as well as...
6060049 Surrogate tolerogenesis for the development of tolerance to xenografts  
6057145 Mass production and long-term preservation of fungivorous nematodes and uses thereof  
A host fungus of a fungivorous nematode is inoculated on a solid medium or an artificial liquid medium containing an industrial vegetable waste or by-product, and then the nematode whose whole body...
6054116 Chimeric mouse for human and mouse immune systems  
This invention is directed to a chimeric mouse capable of mounting murine cellular and humoral immune response, where the chimeric mouse is tolerant of human tissue implanted therein. The chimeric...
6040495 Hairless mouse sensitive to helicobacter pylori  
A hairless mouse designated NS:Hr/ICR is sensitive to H. pylori. This NS:Hr/ICR hairless mouse can be easily infected with H. pylori in its alimentary canal, and is therefore useful as an...
6037520 Human breast carcinoma cell line capable of production of a spontaneously metastasizing tumor in animals for use in anticancer drug testing  
An adherent, stable, continuous human breast carcinoma cell line (GI-101A) has been produced from an infiltrating ductal breast carcinoma xenograft (GI-101) which has been grown and maintained in...
6031150 Sulfonylurea receptor trangenic rodents  
The present invention is directed to a method of detecting persistent hyperinsulinemic hypoglycemia of infancy comprising obtaining a sample comprising patient nucleic acids from a patient tissue...
6028245 Transgenic animals overexpressing MDM2  
The present invention relates to transgenic, non-human animals overexpressing a MDM2 gene. These animals model MDM2 over-expression associated with human tumors, display a major phenotype...
6025540 Transgenic non-human mammals producing EC-SOD protein in their milk  
The present invention relates to a transgenic non-human mammal comprising a DNA sequence encoding human extracellular superoxide dismutase (human EC-SOD) or a variant thereof which is expressed in...
6018096 Animal model for engraftment, proliferation and differentiation of human hematopoietic stem cells  
A chimeric, non-human, genetically-immunocompetent mammal is disclosed. The hematopoietic system of the mammal has human passaged bone marrow stromal cells and human hematopoietic stem cells...
5994617 Engraftment of immune-deficient mice with human cells  
A process for transplanting into an immunodeficient mouse, which is deficient in T-cells and B-cells, human cells to form a chimeric mouse is provided. The transplanted human cells proliferate and...
5969211 Pantropic retroviral vectors for gene transfer in mollusks  
A method for introducing foreign nucleic acid sequences into marine mollusks. A pantropic retroviral vector containing a foreign gene sequence is introduced into fertilized mollusk embryos by...
5965149 Granular formulation of biological entities with improved storage stability  
A method for preparing granules containing pesticidal or herbicidal biological organisms which can be stored for prolonged periods and conveniently dispensed is provided. Compositions are provided...
5962321 Leukemia inhibitory factor from mammalian species and use thereof to enhance implantation and development of embryos  
Leukemia inhibitory factor or LIF as an addition to culture media promotes the development of embryos to the implantation stage. Growth in the presence of LIF increases the percentage of embryos...
5952488 Androgen regulation with DNA sequences of rat probasin gene  
A DNA sequence (-426 to +28 base pairs) cloned from the probasin (PB) gene promoter region confers androgen regulation in cell culture and prostate specific expression in transgenic non-human...
5944652 Method for breeding chickens  
Disease resistance in chickens has been associated with the Rfp-Y system of major histocompatability genes in chickens. A method for breeding chickens to produce disease resistant offspring...
5939598 Method of making transgenic mice lacking endogenous heavy chains  
The subject invention provides non-human mammalian hosts characterized by inactivated endogenous Ig loci. The hosts are produced by repetitive transformations of embryonic stem cells by homologous...
5932250 Anti-cholesterolemic egg, vaccine and method for production, and use  
The present invention is directed to the treatment of vascular disorders particularly arteriosclerosis and atherosclerosis in warm-blooded animals. The invention encompasses the ingestion, by...
5925802 Functional reconstitution of SCID-bo mice with bovine fetal hematopoietic tissues  
The present invention provides a non-human chimeric mammal, comprising a severe-combined immunodeficient mammal engrafted with bovine immune system tissues, wherein said chimeric mammal is...
5917123 Transgenic mice containing a nucleic acid encoding tumor necrosis factor-α under the control of a cardiac specific regulatory region  
The present invention provides transgenic nonhuman mammals that exhibit elevated levels of tumor necrosis factor alpha in myocardium relative to nontransgenic control mammals, and methods for...
5880326 Models for measuring the sense of smell  
The invention provides methods and compositions for measuring the sense of smell, including animals having general anosmia as a result of a genetic mutation. The genetic mutation disrupts a...
5866757 Engraftment and development of xenogeneic cells in normal mammals having reconstituted hematopoetic deficient immune systems  
Non-human chimeric mammals are created from a mammal having hematopoietic cells replaced with hematopoietic cells from a hematopoietic deficient mammal donor, and optionally in which xenogeneic...
5849288 Method for production of monoclonal antibodies in chimeric mice or rats having xenogeneic antibody-producing cells  
Non-human chimeric mammals are created from a mammal having hematopoietic cells replaced with hematopoietic cells from a hematopoietic deficient mammal donor, and in which xenogeneic hematopoietic...
5849991 Mice homozygous for an inactivated α 1,3-galactosyl transferase gene  
Human pre-formed xenoantibodies play an important role in the hyperacute rejection response in human xenotransplantation. Disclosed are materials and methods for removing or neutralizing such...
5824841 Tetraploid shellfish  
Provided by this invention are novel tetraploid mollusks, including oysters, scallops, clams, mussels and abalone. Also, provided are a method for producing the tetraploid mollusks and a method for...
5770786 Method for the isolation and/or testing of genes and promoters involved in plant-nematode interactions using plants of the genus arabidopsis  
The invention provides a method for infecting a root of a plant of the genus Arabidopsis with a plant parasitic nematode under monoxenic conditions, comprising the steps of: (a) contacting the root...
5679005 Model of corrected transposition of the great arteries  
This invention relates to the creation of an animal model which has the circulatory physiology of the fatal human infant condition of transposition of the great arteries (TGA) by surgically...
5602301 Non-human mammal having a graft and methods of delivering protein to myocardial tissue  
Described are preferred myocardial grafts of skeletal myoblasts or cardiomyocytes, and cellular compositions and methods useful in obtaining the grafts. The myocardial grafts are stable and can be...
5602302 Models for asthma guinea pig  
The present invention relates to a method of preparing bronchial hypersensitive or hyposensitive guinea pigs by selective breeding on the basis of bronchial sensitivity to inhalant chemicals...
5557033 Method of increasing egg production in avian species by active immunization against vasoactive intestinal peptide  
The present method of increasing egg production in laying turkey hens includes actively immunizing the hens with vasoactive intestinal peptide. The peptide is conjugated to a protein to induce an...
5549884 Rat or mouse exhibiting behaviors associated with human schizophrenia  
This invention provides a unique and surprisingly accurate animal model for human schizophrenia. The animals are brain damaged while prepubescent. The brain damage consists of a ventral hippocampus...
5183950 Commercial storage and shipment of entomogenous nematodes  
Methods and materials for inducing anhydrobiosis in entomogenous nematode infective juveniles and then maintaining and storing them in an apparently anhydrobiotic state are described. Infective...
Matches 251 - 300 out of 300 < 1 2 3 4 5 6