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7380477 |
Method for tissue osmometry
A measurement system including a staging unit including a substrate having piezoelectric properties and a conductive electrode formed on the substrate, the conductive electrode including an area...
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7282362 |
Tray with protrusions
A feeding tray for retaining a liquid nutrient liquid is provided for use with a multiwell filter plate. The feeding tray includes a flat support surface surrounded by walls which retain liquid on...
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7182509 |
Nanoliter osmometer and method of operation
The invention is an apparatus for determining a temperature at which a phase change occurs in a fluid sample, a method for measuring a temperature at which a phase change occurs in a sample and a...
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7179637 |
Apparatus and method for using intestinal segments or their substitutes in high-throughput analysis of compound absorption
An apparatus for high-throughput analysis of compound absorption in a controlled environment that closely resembles in-vivo conditions. The apparatus includes at least one tissue-receiving...
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7172859 |
System and method for optimizing tissue barrier transfer of compounds
The present invention relates to high-throughput systems and methods to prepare a large number of component combinations, at varying concentrations and identities, at the same time, and...
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7148060 |
Feeding tray for multiwell test apparatus
A feeding tray for retaining a nutrient medium is provided for use with a multiwell filter plate. The feeding tray includes an inclined support surface surrounded by walls that retain nutrient...
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7111502 |
Systems and methods for reducing the effect of corruptive signals during nanoliter osmometry
An osmolarity measuring system includes the ability to recognize patterns within the electrical profile of nanoliters of fluid an account for corruptive signals in the electrical profile. These...
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7039527 |
Method for measuring diffusivities of compounds using microchips
A method for determining the molecular diffusivity of a solute in a microchannel where a solute is introduced into a first end of a microchannel and a first concentration profile is measured at...
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7017394 |
Tear film osmometry
Osmolarity measurement of a sample fluid, such as tear film, is achieved by depositing an aliquot-sized sample on a sample receiving substrate. The sample fluid is placed on a sample region of the...
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6779384 |
Device and method for measuring a diffusion coefficient of nano-particle fluid through hollow-fiber micropores
A particle diffusion coefficient measuring device is provided with a hollow-fiber including micropores on its surface. The hollow-fiber provides a passage for particle suspension to transport...
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6595042 |
Method for demonstrating breathability
A method for demonstrating breathability by providing an aliquot of liquid in a container having an opening; forming a closed system by securing a film about the opening; imparting evaporation on...
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6450014 |
Method and apparatus for measuring osmotic pressure
A method and apparatus are provided for the measuring osmotic pressure of a solution. A sample of a solution is placed into a sample cell above a membrane supported in the sample cell and the...
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6422066 |
Sensor capsule for CO2 sensor
A sensor capsule to facilitate positioning of an analyte sensitive element such as a CO 2 sensor at the end of a fiber optic probe, which discloses a dye layer defined by a dye well, fluorescent...
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6397666 |
Method for generating a solution with a predetermined osmotic pressure
A method is provided for determining the concentration of a solution having a predetermined osmotic pressure and/or for generating a solution with a predetermined osmotic pressure. The method is...
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6360588 |
Materials and methods for the analysis of substances passing through a membrane
The subject invention pertains to the efficient and accurate detection and analysis of materials passing through a membrane. In a specific example the transport of materials through skin is...
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6335202 |
Method and apparatus for on-line measurement of the permeation characteristics of a permeant through dense nonporous membrane
This invention relates to a method and apparatus for on-line measurement of permeation characteristics (transmitting chemicals) through dense nonporous membrane. This invention is intended to...
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6298713 |
Method for determination of water transport in biocompatible materials
A method is provided for determining the water diffusion coefficient of a biocompatible material. The method measures water diffusion through the biocompatible material by detecting the presence of...
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6269679 |
System and method to characterize gas transport properties
An artificial capillary testing apparatus (ACTA) is provided for evaluation of gas transport/exchange properties of a fluid. A sample fluid, having a known of measured partial gas pressure, is...
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6267003 |
Method for measuring changes in osmotic pressure
A method is provided which allows for monitoring changes in osmotic pressure of a sample as a function of time and/or temperature. This is accomplished by placing a sample of a solution at an...
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6251859 |
Deepithelialized skin diffusion cell system
A deepithelialized skin cell diffusion system which can be used to select topical gel and cream formulations containing human other wound healing promoters such as plasma fibronectin. The...
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6234004 |
Method for measurement of flow velocity or diffusivity, microsensor and application of such microsensor
The invention relates to a method and a microsensor for measurement of transport coefficients like diffusivity or flow velocity. The microsensor has a reservoir provided with a mouth and a...
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6202475 |
Predicting logarithmic reduction values
A method of predicting logarithmic reduction values for a membrane filtration system having a filtrate flow portion and a bypass flow portion relative to a filtrate permeable membrane with stable...
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6119506 |
Apparatus and method for determining transport properties of porous materials
An apparatus and method for measuring the mass transport properties of pos materials. The apparatus is a permeation or diffusion cell that comprises two outer portions with longitudinal channels...
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6076395 |
Constant stress diffusion cell with controllable moisture content
A device for measuring the concentration changes of a vapor at various moisture contents ranging from saturation to dry and under different confining stress as it diffuses through a porous media...
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5983708 |
Gravimetric cup
A gravimetric cup for containing a liquid sample to be measured for moisture or vapor transmission loss therefrom, such gravimetric cup having a lower cup body and a cover, the cover having an...
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5889195 |
Measuring arrangement for determining the concentration of gases from liquid media
A measuring arrangement for determining the concentration of gases dissolved in a liquid is proposed, which has a simple design and makes possible the use of known gas-measuring apparatus based on...
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5762959 |
Microencapsulation of cells
In accordance with the present invention, it has been discovered that a major reason for the failure to achieve successful in vivo transplantation in large mammalian species has been flaws...
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5738826 |
Ussing chamber
An apparatus which is in the nature of an Ussing chamber utilizing a discrete separation between the two chambers in which solutions used for testing tissue are located is described. The cartridge...
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5723769 |
Diffusion cell
A Diffusion cell for use in monitoring levels of gases or volatile organic compounds within bulk media such as ground water, effluent, or air. The diffusion cell is of sealed hollow construction...
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5696314 |
Multilayer enzyme electrode membranes and methods of making same
An electrochemical sensor is designed for use in detecting a concentration of an analyte in a sample solution. The sensor to have a longer useful lifetime, improved stability and improved response...
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5665904 |
Osmometric device and process for determining the analyte content of a solution of mixed substances
In an osmometric measurement device and a method for determining the content of an analyte in a solution of a mixture of substances including the analyte, the mixture solution is admitted to a...
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5659130 |
Simple device for testing chemical permeation
A simple test device for protection against chemical permeation is disclosed. It includes a test chamber, a solvent sample cup, upper and lower fixing plates, upper and lower gaskets, an air...
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5612222 |
In vitro test for dermal corrosive properties
Methods and a device for determining the corrosivity of a substance to human skin or membrane are disclosed. In one approach, corrosivity is evaluated by measuring the time required for the test...
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5599688 |
Device and method for circulating fluid over a membrane
The invention provides a compact device and simple method for circulating fluid over the surface of a membrane. The device comprises a housing that in combination with the surface of the membrane...
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5591636 |
Membrane holder
The invention provides a compact device of simple construction for holding a membrane in contact with a pair of fluids, one on each side of the membrane. According to the invention, the membrane...
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5490415 |
Diffusion test apparatus and method
A diffusion test apparatus (2), used to test diffusion of a drug within a vehicle through a test membrane (8), includes a receiver assembly (6) and a donor assembly (4) secured to one another. The...
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5408865 |
Transdermal cell test matter volume-adjustment device
In a transdermal cell, a matter volume-adjustment male device includes the lower opening end of the through-space structure having inner wall female threads mateable with first male threads of a...
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5388449 |
Osmolarity sensor
An osmolarity sensor continuously senses an osmolarity of a fluid. A principle of operation is based on achieving an equilibrium of a vapor pressure of a specimen solution with a vapor pressure of...
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5296139 |
Diffusion cell with filter screen
A diffusion cell to facilitate the automated removal of test aliquots of liquid from a receptor chamber of the diffusion cell so as to determine percutaneous absorption through a membrane of a...
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5211055 |
Apparatus for the selective determination of the concentration of a substance dissolved in a solvent
This invention relates to an apparatus for the selective determination of e concentration of a substance dissolved in a solvent by means of an osmosis cell. The osmosis cell according to the...
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5198109 |
Diffusion cell
A diffusion cell to facilitate the automated removal of test aliquots of liquid from a receptor chamber of the diffusion cell so as to determine percutanous absorption through a membrane of a donor...
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5183760 |
Apparatus for in vitro determination of substances across membranes, biological tissues, or cell cultures
An apparatus for determining transport characteristics across membranes and tissue sections comprises a plurality of cell blocks, where each cell block includes a pair of half-cells which hold the...
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5156041 |
Method and apparatus for determining permeation behavior of foreign molecules through solids
Methods and apparatus for determining the permeation behavior of foreign fluid molecules into solids whereby the results are typically obtained in less than one day. In a principal embodiment,...
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5143080 |
In vivo osmometer
A first exemplary embodiment of an osmometer for the in vivo measurement of the osmolarity of a bodily fluid such as tears or sweat comprises a detachable, preferably disposable, probe in...
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5141873 |
Process for the selective determination of the concentration of a substance dissolved in a solvent by osmotic pressure measurement
This invention relates to a process for the selective determination of the oncentration of a substance dissolved in a solvent by means of an osmosis cell. The osmosis cell according to the...
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5053340 |
In vitro test for dermal toxic properties
A membrane support, reagent and method determines, in vitro, skin irritation properties of individual compounds and/or mixtures is disclosed. The material to be tested is applied directly to the...
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5005403 |
Process and apparatus for the determination of the concentration of a substance dissolved in a solvent by means of an osmometer
In a process for the determination of the concentration of a substance dissolved in a solvent by means of an osmometer, comprising a two-chamber system with a first chamber having an osmosis cell...
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4891968 |
Process for the determination of the concentration of substances dissolved in a solvent by means of osmotic cells
This invention relates to a process and apparatus for the determination of he concentration of substances dissolved in a solvent. For this purpose, an osmotic cell is used, in which first, by means...
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4863696 |
Apparatus for the percutaneous absorption of fluids
An orifice assembly for use in connection with diffusion cells for the percutaneous absorption of fluids which is composed of a pair of resiliant and mating members having structure for securely...
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4860577 |
Osmotic applications of hollow fibers
An osmometer for use in the measurement of gases, liquids and solids is disclosed. The osmometer includes a semipermeable hollow fiber, capable of passing liquids but not dissolved solids. The...
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