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7623946 |
System and method that will synchronize data acquisition and modulation in a comprehensive two (multi) dimensional chromatography (separation) system to enable quantitative data analysis
The present invention is a comprehensive two-dimensional gas chromatograph system and method including a modulator wherein the pulsing of the modulator is synchronized with data acquisition so that...
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7611901 |
Method for determining the content of diesel fuel in a lubricating oil of a combustion engine
A method for determining proportion of diesel fuel in a lubricating oil of a combustion engine, including: forming a mixture containing an oil sample and a C 5 hydrocarbon such as a C 5 alkane;...
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7606668 |
Gas monitoring system and method
A method and apparatus for interfacing a plurality of volumetric measurement systems, each of which includes a gas measurement and a flow measurement system, to a host system via an interface unit.
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7598049 |
Methods for diagnosis of Alzheimer's Disease in blood samples
The inventors have discovered a collection of proteinaceous biomarkers (“AD biomarkers) which can be measured in peripheral biological fluid samples to aid in the diagnosis of neurodegenerative...
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7596453 |
Digital scale
A digital scale is provided that switches a measuring interval according to the amount of variation of sampled data, and computes a weight. Embodiments include a scale with pre-stored scale...
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7588726 |
Vapor analysis apparatus and method
A vapor analysis system comprising a vapor analyzer capable of collecting and analyzing a vapor sample for detection of a compound that may be contained within the vapor sample. A controller is...
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7587285 |
Method for identifying correlated variables
According to various embodiments, variables are grouped in an unsupervised manner after principal component analysis of a plurality of variables from a plurality of samples. A number of principal...
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7580799 |
Method for characterizing and analyzing 3-D shapes of molecules utilizing steric multiplets
Steric features inherent in the three dimensional disposition of atoms in molecules can be represented as multiplets using a defined set of steric descriptors. The resulting multiplets can be...
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7575876 |
Biomarkers for neurodegenerative disorders
The present invention provides methods for diagnosing neurodegenerative disease, such as Alzheimer's Disease, Parkinson's Disease, and dementia with Lewy body disease by detecting a pattern of gene...
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7572639 |
Method and apparatus for predicting pregnancy outcome
A method for predicting pregnancy outcome includes measuring blood levels of hCG-hg and progesterone in a pregnant woman, determining a rate of change of progesterone levels from the blood...
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7558682 |
Chromatograph mass spectrometer
An exact centroid spectrum with a mass number corrected is determined from a profile spectrum adjacent to a plurality of peaks. Regarding a profile spectrum determined by a mass spectrometer,...
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7556716 |
Method for recording the boiling curve of liquids and device for carrying out the method
Described is a method for recording the boiling curve of liquids, in particular petroleum products and/or solvents, in which a sample amount of the liquid to be analyzed is evaporated and...
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7544931 |
Mass-analyzing method
In a mass analysis of a sample, candidate compositions Y of a fragment ion produced by a dissociating operation are deduced from the mass of that fragment ion (Steps S 6 to S 9 ). If the number of...
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7544930 |
Tandem type mass analysis system and method
The present invention provides a tandem type mass analysis system capable of carrying out the differential analysis with high efficiency by the tandem type mass analysis. A predetermined number of...
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7531137 |
Substance detection system
A substance detection system having an electronic nose and classifier. The system may extract feature from the electronic signals representing the smells from the electronic nose sensing an unknown...
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7526405 |
Statistical signatures used with multivariate statistical analysis for fault detection and isolation and abnormal condition prevention in a process
A system and method for monitoring a process in a process plant and detecting an abnormal condition includes collecting data representative of the operation of the process, performing a...
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7523026 |
Proteome analysis method and proteome analysis system
A proteome analysis method includes using a tandem type mass spectrometer to calculate bond dissociation energy by using molecular simulation, using the bond dissociation energy to obtain...
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7519519 |
Signature projection score
Disclosed is a method for predicting the biological activity of a compound by the similarity of its drug signature score to the scores of a plurality of known drug signatures.
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7519479 |
Slope detection for measuring gas concentration
A process and apparatus for sensing gas concentration in a gas stream involves producing a succession of difference values representing differences between successive sample values of a succession...
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7512499 |
System and method for determining substrate doping density in metal oxide semiconductor devices
A system and method are disclosed for very accurately determining a value of a substrate doping density in a metal oxide semiconductor device. A plurality of values of threshold voltage of a device...
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7504230 |
Method of identifying a useful set of signal transduction proteins from a multiplicity of potentially useful proteins
The present invention is a cell-based method of identifying a set of signal transduction proteins having an intracellular localization pattern responsive to toxic compounds. The method requires...
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7502693 |
Spectral feature-based identification of substances
A spectroscopic identification method and system are provided that uses the primary or main spectroscopic features of a source, such as those as arising from chemical functional groups, to describe...
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7501621 |
Data acquisition system for a spectrometer using an adaptive threshold
A data acquisition system and method are described that may be used with various spectrometers. The data acquisition system may include an ion detector and a processing circuit. The processing...
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7499807 |
Methods for recalibration of mass spectrometry data
Disclosed are methods for recalibrating mass spectrometry data that provide improvement in both mass accuracy and precision by adjusting for experimental variance in parameters that have a...
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7493225 |
Method for calibrating mass spectrometry (MS) and other instrument systems and for processing MS and other data
A method for obtaining at least one calibration filter for a Mass Spectrometry (MS) instrument system. Measured isotope peak cluster data in a mass spectral range is obtained for a given...
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7493219 |
Method of discriminating particle groups and particle analyzer
A method for discriminating particle groups comprises generating, by a particle analyzer, a particle characteristic distribution histogram in which the abscissa indicates respective channels for...
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7485852 |
Mass analysis method and mass analysis apparatus
The present invention achieves a mass analysis method that can identify protein or peptide with high speed and high sensitivity. A mass spectrum is obtained from a standard sample of healthy...
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7482498 |
Device and process for nucleophilic fluorination
The invention relates to a device and a process for nucleophilic fluorination of a substance, especially for synthesis of an 18 F-labeled substance for examination using a positron emission...
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7480062 |
Automated process control using parameters determined from a photomask covered by a pellicle
Provided is a method of controlling a photolithography cluster or a subsequent fabrication cluster using optical metrology to determine profile parameters of a photomask structure covered with a...
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7477993 |
Multiple sensing system and device
The present invention provides a distributed sensing system in a networked environment for identifying an analyte, including a first sensor array connected to the network comprising sensors capable...
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7472153 |
Method for exploiting bias in factor analysis using constrained alternating least squares algorithms
Bias plays an important role in factor analysis and is often implicitly made use of, for example, to constrain solutions to factors that conform to physical reality. However, when components are...
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7469186 |
Finding usable portion of sigmoid curve
Various technologies are described by which the usable portion or threshold value of a sigmoid curve is found. Such techniques can be useful, for example, when determining the concentration or...
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7463982 |
Liquid class predictor for liquid handling of complex mixtures
A method of establishing liquid classes of complex mixtures for liquid handling equipment. The mixtures are composed of components and the equipment has equipment parameters. The first step...
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7462818 |
Determination of chemical empirical formulas of unknown compounds using accurate ion mass measurement of all isotopes
A method of determining an empirical formula of an analyte ion from a measured mass spectrum including a main peak and one or more isotope peaks. The method comprises comparing a relative isotopic...
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7460961 |
N-TRADD active site and uses thereof
The present invention relates to the three dimensional solution structure of the N-terminal domain of TNFR-1 associated death domain protein (“N-TRADD”), as well as the identification and...
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7460959 |
System and method for estimating oxygen concentration in a mixed gas experiencing pressure fluctuations
A method for estimating the concentration of a particular gas in a gas mixture having a fluctuating pressure is provided. A sensor output signal indicating the concentration of a particular gas in...
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7454296 |
Biosensor with multi-channel A/D conversion and a method thereof
A biosensor with multi-channel A/D conversion and a method thereof are provided. The present biosensor includes a chip generating a time-dependent analog signal in response to a content of a...
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7442921 |
Protein profiles with atmospheric pressure ionization
The invention relates to the acquisition of mass spectra of complex protein mixtures, often called protein profiles, for example to search for biomarkers which indicate stress situations, or to...
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7430479 |
System and method for analyzing content data
The system and method provide security and cargo handling personnel a versatile tool to rapidly check cargo for hidden radiological materials, explosives, drugs, and chemical weapons material....
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7429727 |
Method, apparatus, and program product for quickly selecting complex molecules from a data base of molecules
The disclosed technology relates to the analysis of dissociation spectrum data that includes spectral peaks that represent fragments of a parent ion. The parent ion includes molecular subunits that...
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7416698 |
Molecular topological fractionation of macromolecules
A process for characterizing a sample comprising a population of linear macromolecules of interest ( 104 ) and a population of long chain branched macromolecules of interest ( 103 ), the process...
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7412334 |
Mass spectrometer and method for enhancing resolution of mass spectra
A mass spectrometer comprises an ion detector, an analog-to-digital (A/D) converter, a sample adjuster, and an adder. The A/D converter is configured to receive and sample an analog signal from the...
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7409299 |
Method for identifying components of a mixture via spectral analysis
Spectra data collected from a mixture defines an n-dimensional data space (n is the number of data points), and application of PCA techniques yields a subset of m-eigenvectors that effectively...
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7409298 |
Matched filtration with experimental noise determination for denoising, peak picking and quantitation in LC-MS
An improved system and method of analyzing sample data that increases the reliability of peak (compound) detection and identification in the presence of chemical and/or random noise. The sample...
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7395158 |
Method of screening for disorders of glucose metabolism
A method of screening for disorders of glucose metabolism such as impaired glucose tolerance and diabetes allows prevention, or early detection and treatment of diabetic complications such as...
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7391017 |
Mass scale alignment of time-of-flight mass spectra
The invention generates mass scale comparability between mass spectra which are acquired in time-of-flight mass spectrometers, particularly with ionization by matrix-assisted laser desorption....
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7391015 |
System and method for data collection in recursive mass analysis
Systems, methods, and computer programming for collecting data using a mass spectrometer comprising a particle detector or other mass analyzer. A data collection such as a tree or array structure...
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7373256 |
Method for the identification of molecules and biomarkers using chemical, biochemical and biological data
This invention pertains generally to the field of multivariate statistics, and in particular to new methods for the analysis (e.g., chemometrics) of chemical, biochemical, and biological data,...
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7366617 |
Mass determination for biopolymers
A method for determining the masses of ions of a sample that contains a known class of biopolymers and is measured with a mass spectrometer having a statistical or pseudo-statistical error...
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7365539 |
Method of using G-matrix fourier transformation nuclear magnetic resonance (GFT NMR) spectroscopy for rapid chemical shift assignment and secondary structure determination of proteins
The present invention presents a new approach to rapidly obtaining precise high-dimensional NMR spectral information, named “GFT NMR spectroscopy”, which is based on the phase sensitive joint...
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