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7623997 |
Computer-implemented biological sequence identifier system and method
A method of: submitting reference sequences to a taxonomic database to produce taxonomic results; and reporting a taxonomic identification based on the taxonomic results. The reference sequences...
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7623969 |
Gene discovery for the system assignment of gene function
The invention provides a method for assigning a cellular function to a component of a biochemical system. The method involves (a) determining a multidimensional shape space for one or more...
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7622253 |
Classification of patients having diffuse large b-cell lymphoma based upon gene expression
Methods and kits for classifying patients having diffuse large B-cell lymphoma (DLBCL) based upon expression of a plurality of genes are disclosed. Real-time quantitative RT-PCR can be used to...
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7620502 |
Methods for identifying sets of oligonucleotides for use in an in vitro recombination procedure
In silico nucleic acid recombination methods, related integrated systems utilizing genetic operators are used to identify sets of oligonucleotides for in vitro recombination.
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7606784 |
Uncertainty management in a decision-making system
Systems and methods are provided for constructing and evaluating a story of interest. The system includes a plurality of decision algorithms. Each decision algorithm is operative to quantify at...
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7603240 |
Peptide identification
The present invention provides a peptide identification method along with related peptide databases, method of generating the databases, computer usable media, and computer program products. The...
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7599802 |
V-life matching and mating system
A system for producing virtual offspring including means for acquiring genetic material from users. The system further includes means for analyzing the acquired genetic material for determining at...
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7599801 |
Profile database and method for preparing profile
Provided is a means capable of high-speed analysis of a large-scale correlation among sequences of biopolymers and reutilization of any analyzed profile. A large-scale profile database 103 is...
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7599800 |
Apparatus and method for coding genetic information
Provided are an apparatus and a method for coding genetic information. An aligning unit aligns sample genetic information, wild-type probe genetic information, and mutant-type probe genetic...
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7599799 |
Methods for using co-regulated genesets to enhance detection and classification of gene expression patterns
The present invention provides methods for enhanced detection of biological response patterns. In one embodiment of the invention, genes are grouped into basis genesets according to the...
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7593819 |
Internal calibration standards for electrophoretic analyses
The present teachings relate, among other things, to polynucleotide sequencing, fragment analysis and sample/lane tracking, and to polynucleotide sequencers and analyzers that employ optical...
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7587284 |
Gene synthesis software
Pieces of software and databases are used to facilitate the design and synthesis of genes. The synthesis techniques allow identification, quantification, transcription, translation, and...
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7587282 |
Statistical methods for analyzing biological sequences
Statistical algorithms that are useful to aid in the identification of evolutionarily conserved amino acid positions within a family of proteins, and in the identification of interacting amino acid...
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7584059 |
Inhibition of immune complex formation
Polypeptides and other compounds that can bind specifically to the C H 2-C H 3 cleft of an immunoglobulin molecule, and methods for using such polypeptides and compounds to inhibit Fc-mediated...
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7574306 |
Method and system for optimization of polymer sequences to produce polymers with stable, 3-dimensional conformations
One embodiment of the present invention is directed to a method and system for designing the monomer sequence of a polymer to produce a particular polymer that adopts an initially specified,...
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7574305 |
Concurrent optimization in selection of primer and capture probe sets for nucleic acid analysis
Disclosed is a method of iteratively optimizing two (or more) interrelated sets of probes for the multi-step analysis of sets of designated sequences, each such sequence requiring, for conversion,...
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7567870 |
Multiparameter analysis for predictive medicine
The invention provides a method of determining a comparative expression profile in an individual by comparing the expression levels of a sample of molecules in a population of molecules in a...
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7565248 |
Computer system for designing oligonucleotides used in biochemical methods
A method for determining one or a set of optimal reagent oligonucleotide sequences used in a biochemical method for evaluating a target nucleic acid sequence having a target feature by defining a...
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7561974 |
System and method for identifying genes
A system and method for identifying genes that employs a pattern database, an input device for inputting a DNA sequence, and a processor for processing the DNA sequence and patterns to identify a...
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7561973 |
Methods for determining properties that affect an expression property value of polynucleotides in an expression system
A method of determining a property that affects expression of polynucleotides in an expression system. A plurality of polynucleotides, each encoding a polypeptide sequence, is constructed. An amino...
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7561972 |
Synthetic nucleic acids for expression of encoded proteins
A method of designing a polynucleotide sequence encoding a polypeptide sequence of a predetermined polypeptide is provided. A frequency lookup table corresponding to an expression system is...
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7558681 |
Method of determining plant species with pyrolysis-gas chromatography
A method of identifying a plant species includes the steps of: preparing a fragment of the plant; heating the fragment to obtain lignin from the fragment; gasifying the lignin at a high temperature...
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7558679 |
System and method for irradiating a sample
Method and system for footprinting a nucleic acid molecule. A sample consists of a nucleic acid molecule in an environment in which —OH radicals are generated when the environment is irradiated...
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7555392 |
Method for determining metabolic flux
A method for determining metabolic flux distribution of a cell, which comprises the steps of:
1) creating a stoichiometric matrix based on formulas of biochemical reactions from a substrate to a...
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7539607 |
Computer system and method of calculating a pharmacokinetic behavior of a chemical substance in insects
Computer system for calculating a pharmacokinetic behavior of a chemical substance in insects, comprising:
a physiologically based pharmacokinetic simulation model ( 102 ) of an insect for...
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7517494 |
Test tray and test system for determining response of a biological sample
The present invention provides test trays and test tray systems for assessing the response of a biological sample to a compound or combination of compounds. The compounds or combinations are...
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7516351 |
Distributed testing apparatus and host testing apparatus
There is provided a group of testing apparatuses that realizes high-level testing and high quality medical treatment by conducting tests using apparatuses and facilities that are located in a...
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7512498 |
Streaming processing of biological sequence matching
A data system is provided for biological sequence matching. The system includes a system memory, a cache controller coupled to the system memory, a first cache coupled to the cache controller to...
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7512497 |
Systems and methods for inferring biological networks
Described herein is a system for inferring one or a population of biochemical interaction networks, including topology and chemical reaction rates and parameters, from dynamical or statical...
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7512496 |
Apparatus, method, and computer program product for determining confidence measures and combined confidence measures for assessing the quality of microarrays
An apparatus, method, and computer program product are provided for determining a confidence measure for the output of a process for assessing proteomic and genomic information samples. Typically,...
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7476853 |
Ion fragmentation by reaction with neutral particles
The invention relates to a method and apparatus for the fragmentation of large molecules, especially biopolymers. The invention consists in reacting analyte ions with excited or radical neutral...
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7467047 |
Method of discovering patterns in symbol sequences
A method of discovering one or more patterns in two sequences of symbols S 1 and S 2 includes the formation, for each sequence, of a master offset table that groups for each symbol the position...
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7462354 |
Method and system for optimizing minigenes and peptides encoded thereby
The invention relates to the field of biology. In particular, the invention relates to a method and system for designing optimized multi-epitope vaccines having selected combinations of amino acid...
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7451047 |
System and method for programatic access to biological probe array data
An applications programming interface is described that includes code libraries that enable transfer of pixel data, intermediate results data, or both, from a data structure or data file directly...
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7444243 |
Probabilistic method for determining nucleic acid coding features
The present invention is in the field of bioinformatics, particularly as it pertains to gene prediction. More specifically, the invention relates to the probabilistic analysis of nucleic acid...
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7436522 |
Method for determining the 3D coordinates of the surface of an object
A method serves to determine the 3D coordinates of an object. The 3D coordinates of a partial surface ( 6 ) of the object are determined by a 3D measuring device ( 3 ), which includes one or more...
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7430475 |
Biological discovery using gene regulatory networks generated from multiple-disruption expression libraries
Embodiments of this invention include application of new inferential methods to analysis of complex biological information, including gene networks. In some embodiments, disruptant data and/or drug...
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7429727 |
Method, apparatus, and program product for quickly selecting complex molecules from a data base of molecules
The disclosed technology relates to the analysis of dissociation spectrum data that includes spectral peaks that represent fragments of a parent ion. The parent ion includes molecular subunits that...
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7427480 |
Life sciences business systems and methods
Improved life sciences business systems and methods are disclosed. One or more genomes are scanned for single nucleotide polymorphisms. The polymorphisms are assigned to haplotype blocks, and...
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7424371 |
Nucleic acid analysis
A sample nucleic acid sequence is compared against a database to find a matching sequence. In one embodiment, this comparison is accomplished with a table look-up approach that involves using...
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7424369 |
Physical-chemical property based sequence motifs and methods regarding same
A data analysis system, program, and/or method, e.g., a data mining/data exploration method, using physical-chemical property motifs. For example, a sequence database may be searched for...
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7421347 |
Identifying oligonucleotides for in vitro recombination
“In silico” nucleic acid recombination methods, related integrated systems utilizing genetic operators and libraries made by in silico shuffling methods are provided.
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7416524 |
System, method and computer program product for fast and efficient searching of large chemical libraries
A system, method, and computer program product for fast and efficient searching of large virtual combinatorial libraries based on a fitness function. According to the method of the present...
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7415359 |
Methods and systems for the identification of components of mammalian biochemical networks as targets for therapeutic agents
Systems and methods are presented for cell simulation and cell state prediction. For example, a cellular biochemical network intrinsic to a phenotype of a cell can be simulated by specifying its...
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7415144 |
Cell observation device and cell observation method
The cell observation device and method aims to easily study the correlation between initial states of cells and their reactions without using a synchronous culture method. For this purpose, the...
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7410777 |
Non-endogenous, constitutively activated human G protein-coupled receptors
Disclosed herein are constitutively activated, non-endogenous versions of endogenous human G protein-coupled receptors comprising (a) the following amino acid sequence region (C-terminus to...
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7409297 |
Methods and systems for providing a nutraceutical program specific to an individual animal
The present invention relates to methods and systems for providing an animal with a nutraceutical program that is specifically tailored to address the deficiencies and/or needs of the particular...
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7406385 |
System and method for consensus-calling with per-base quality values for sample assemblies
The present teachings disclose a method for evaluation of a polynucleotide sequence using a consensus-based analysis approach. The sequence analysis method utilizes quality values for a plurality...
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7406384 |
System and method for identifying networks or ternary relationships in complex data systems
A system and method for identifying high order associations between variables in complex systems that is particularly useful where there is no correlation or weak correlation between variables due...
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7400980 |
Methods of detecting DNA variation in sequence data
A method for detecting DNA variation. First, by aligning trace data of a sample DNA sequence to trace data of a reference DNA sequence to produce an aligned sample DNA sequence. Then, inputting the...
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