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7403647 |
Method for identifying an image of a well in an image of a well-bearing component
A method for identifying images of wells in an image of a well-bearing object such as multiwell plates or picowell carriers is provided. An observation component, such as a camera, is used to...
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7400983 |
Information notification sample processing system and methods of biological slide processing
A sample processing system ( 101 ) that may be automated and methods are disclosed where samples) ( 198 ) are arranged on a carrier element ( 197 ) and a process operation control system ( 171 )...
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7400982 |
Automated generation of multi-dimensional structure activity and structure property relationships
The present invention relates to automated generation of multi-dimensional structure activity and structure property relationships.
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7400981 |
Systems, methods, and computer program product for analyzing microarray data
The present invention relates to systems, methods, and computer program products for the analysis of gene expression data, especially data that have been acquired using microarray technologies. In...
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7400980 |
Methods of detecting DNA variation in sequence data
A method for detecting DNA variation. First, by aligning trace data of a sample DNA sequence to trace data of a reference DNA sequence to produce an aligned sample DNA sequence. Then, inputting the...
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7400979 |
Method of identifying inhibitors of Lck
The present invention relates to polypeptides which comprise the ligand binding domain of Lck, crystalline forms of these polypeptides, and the use of these crystalline forms to determine the three...
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7398171 |
Automated quality control method and system for genetic analysis
Aspects of the present invention describe a method and apparatus for automating quality control for gene expression data. A computer based device receives gene expression data associated with a...
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7398120 |
Method and arrangement and computer programme with programme code means and computer programme products for the analysis of neuronal activities in neuronal areas
In a method, arrangement and computer program for analysis of neuronal activities in neuronal areas, signals are recorded, with each signal describing the neuronal activity in one of the neuronal...
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7397026 |
Efficient electron transfer dissociation for mass spectrometry
The present invention relates to, inter alia, methods and apparatuses for electron transfer dissociation (ETD) that vary the internal energy of precursor ions for ETD. The methods and apparatuses...
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7396646 |
Alien sequences
The present invention provides sequences and reagents for preparing microarrays with internal controls. Specifically, the present invention defines and provides sequences that are not present in...
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7395161 |
Polymodal biological detection system
The present invention relates to a method and system for providing biological detection. The system includes: at least one polymodal sensor for collectively detecting at least two conditions; and...
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7395160 |
Quality assurance/quality control for electrospray ionization processes
The present invention relates to a method of quality assurance/quality control for high-throughput bioassay processes. The method includes generating a bioassay process model, and then comparing...
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7395159 |
Method, system and devices for converting venous blood values to arterial blood values
A methodology for converting venous blood values to arterial blood values provides the advantage of obviating the need for taking arterial blood samples. The method entails (i) measuring arterial...
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7395158 |
Method of screening for disorders of glucose metabolism
A method of screening for disorders of glucose metabolism such as impaired glucose tolerance and diabetes allows prevention, or early detection and treatment of diabetic complications such as...
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7392141 |
Method of preparing a modified granulocyte colony stimulating factor (G-CSF) with reduced immunogenicity
A method of preparing a modified granulocyte colony stimulating factor (G-CSF) protein having reduced immunogenicity relative to human G-CSF comprises the steps of (i) identifying one or more...
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7392140 |
Cellular fibronectin as a diagnostic marker in stroke and methods of use thereof
Methods for the diagnosis and evaluation of stroke and stroke sub-type employ a variety of bio-markers including cellular fibronectin (c-Fn) assembled as a panel for stoke diagnosis and evaluation....
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7391015 |
System and method for data collection in recursive mass analysis
Systems, methods, and computer programming for collecting data using a mass spectrometer comprising a particle detector or other mass analyzer. A data collection such as a tree or array structure...
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7386523 |
K-means clustering using t-test computation
A method, apparatus, and system are provided for k-means clustering using t-test computation. According to one embodiment, k-means clustering is performed on a dataset. In performing k-means...
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7386398 |
Hepatitis C Virus NS5B polymerase inhibitor binding pocket
The HCV NS5B polymerase, when complexed with certain inhibitors, adopts a conformation in which the finger loop region defined by amino acid residues 18 to 35 is displaced to expose a binding...
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7384759 |
Methods and compositions for determinig enzymatic activity and specificity of chalcone O-methyltransferases
The invention provides crystalline O-methyltransferases and isolated non-native O-methyltransferases as well as sets of their structural coordinates. Also provided are methods of predicting the...
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7383261 |
Reference database and method for determining spectra using measurements from an LED color sensor, and method of generating a reference database
To determine spectra, integrated multiple illuminant measurements from a non-fully illuminant populated color sensor may be converted into a fully populated spectral curve using a reference...
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7383135 |
Methods of designing inhibitors for JNK kinases
The present invention relates to a data storage medium encoded with the corresponding structure coordinates of molecules and molecular complexes which comprise the active site-binding pockets of...
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7383134 |
Method and/or system for analyzing biological samples using a computer system
A method and/or system for making determinations regarding samples from biologic sources. A computer implemented method and/or system can be used to automate parts of the analysis.
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7383129 |
Method and system for geo-referencing and visualization of detected contaminants
A system and method are provided for visualizing a scene that is monitored for substance contamination. The scene is scanned with a substance detector to detect a substance, such as a harmful...
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7379824 |
Computational method and apparatus for predicting polypeptide aggregation or solubility
A prediction method for predicting the effect of an amino acid modification on the rate of aggregation (solubility) of a reference polypeptide comprising: calculating the difference in...
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7379823 |
System and method for discovery of biological instruments
A system and methods for integrating laboratory instrumentation and applications to provide a unified control and coordination architecture under a common interface. The system provides mechanisms...
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7379822 |
Protein design automation for protein libraries
The invention relates to the use of protein design automation (PDA) to generate computationally prescreened secondary libraries of proteins, and to methods and compositions utilizing the libraries.
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7379821 |
System and method for open control and monitoring of biological instruments
A system and methods for integrating laboratory instrumentation and applications to provide a unified control and coordination architecture under a common interface. The system may be adapted to a...
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7379820 |
Solution structure of RIP DD and uses thereof
The present invention relates to the three dimensional solution structure of receptor interacting protein dead domain (RIP DD), as well as the identification and characterization of various binding...
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7379601 |
Visualization and processing of multidimensional data using prefiltered and sorting criteria
Complex multidimensional datasets generated by digital imaging spectroscopy can be organized and analyzed by applying software and computer-based methods comprising sorting algorithms. Combinations...
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7375321 |
Dynamics bionems sensors and arrays of bionems sensor immersed in fluids
A bioNEMS device comprises a piezoresistive cantilever having flexing legs of which attach the cantilever to a support and a biofunctionalized portion at the tip. A bias current applied to the legs...
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7374536 |
Method for analysis of pain images
A method uses body images and computer hardware and software to collect and analyze clinical data in patients experiencing pain. Pain location information is obtained by the drawing of an outline...
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7373256 |
Method for the identification of molecules and biomarkers using chemical, biochemical and biological data
This invention pertains generally to the field of multivariate statistics, and in particular to new methods for the analysis (e.g., chemometrics) of chemical, biochemical, and biological data,...
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7373255 |
Method and system for determination of molecular interaction parameters
A method of determining kinetic parameters for a reversible molecular interaction between a ligand immobilized to a solid support surface and a binding partner to the ligand in solution, comprises...
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7373254 |
Disinfestation of medical implants with radiation
The present invention relates to the process of selectively exposing matter to a specific wavelength of electromagnetic energy in sufficient flux density per wavelength to cause or promote a...
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7373253 |
Multi-test analysis of real-time nucleic acid amplification
A method and device are described for analyzing a sample for the presence of a nucleic acid wherein the sample is amplified, illustratively using PCR, in the presence of a fluorescent probe capable...
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H002216 |
Method for testing for bioaccumulation
For use in estimating or predicting bioaccumulation of a chemical analyte, even a surfactant, log P ow values for the analyte may be determined by calculating the log of the ratio of the...
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7369946 |
Method of identifying inhibitors of Tie-2
The present invention relates to polypeptides which comprise the ligand binding domain of Tie-2, crystalline forms of these polypeptides and the use of these crystalline forms to determine the...
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7366617 |
Mass determination for biopolymers
A method for determining the masses of ions of a sample that contains a known class of biopolymers and is measured with a mass spectrometer having a statistical or pseudo-statistical error...
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7365539 |
Method of using G-matrix fourier transformation nuclear magnetic resonance (GFT NMR) spectroscopy for rapid chemical shift assignment and secondary structure determination of proteins
The present invention presents a new approach to rapidly obtaining precise high-dimensional NMR spectral information, named “GFT NMR spectroscopy”, which is based on the phase sensitive joint...
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7363170 |
Transfusion registry network providing real-time interaction between users and providers of genetically characterized blood products
Disclosed is a registry system, including member institutions, in which transfusion donors and recipients are registered following genotyping, which would typically take place in a member...
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7363169 |
Simulating microarrays using a parameterized model
Simulating a microarray includes defining a number of parameters. A microarray is generated according to the parameters using an imaging procedure. The microarray is compared to a known value, and...
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7363168 |
Adaptive baseline algorithm for quantitative PCR
The invention relates to baseline subtraction algorithms developed to reduce tube-to-tube and cycle-to-cycle variabilities during real time PCR amplification. Particularly, the invention relates to...
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7363167 |
Method and system for managing blood products
A method and system for managing blood products and tracking their movement between a central blood test facility and a plurality of hospitals in which a database is provided for entering...
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7363166 |
Computational method for the identification of candidate proteins useful as anti-infectives
The present invention relates to a novel method for the identification of candidate proteins in pathogens useful as anti-infectives and more particularly, the present invention describes a novel...
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7363165 |
Significance analysis of microarrays
Microarrays can measure the expression of thousands of genes and thus identify changes in expression between different biological states. Methods are needed to determine the significance of these...
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7362223 |
Chemical, biological, radiological, and nuclear weapon detection system with environmental acuity
A chemical, biological, radiological, and nuclear weapon detection system is disclosed that heightens its acuity and alertness when it senses that a chemical, biological, radiological, or nuclear...
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7356418 |
Scientist domain-centric user interface and enabling “soft” translation
The scientist domain-centric user interface system may prompt the user to supply scientist-centric information expressed utilizing terminology of a scientific domain, such as biology or analytical...
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7356417 |
Methods, systems and computer program products for dynamic scheduling and matrix collecting of data about samples
Data is collected about samples that possess characteristics that change over time and that are contained in any array of containers arranged in a container spatial relationship. A matrix of cells...
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7356416 |
Method and system for automated inference creation of physico-chemical interaction knowledge from databases of co-occurrence data
Methods and system for automated inference of physico-chemical interaction knowledge from databases of term co-occurrence data. The co-occurrence data includes co-occurrences between chemical or...
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