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8862410 Compositions and methods for discovery of causative mutations in genetic disorders  
The compositions and methods provided herein allow for identification of causative genetic biomarkers for a disease condition or drug response.
8862448 Integrated health data capture and analysis system  
The present invention provides an integrated health care surveillance and monitoring system that provides real-time sampling, modeling, analysis, and recommended interventions. The system can be...
8862409 Methods and apparatus for measuring the contents of a search volume  
A method of measuring the contents of a search volume. The method includes: energizing one or more transmitters so as to transmit electromagnetic wave energy into the search volume; detecting the...
8862196 System and method for automatic detection of a plurality of SP02 time series pattern types  
The disclosed embodiments relate to a patient monitor for evaluating a patient. The patient monitor may comprise a sensor that is adapted to detect a sound associated with breathing of the patient...
8855938 Minimization of surprisal data through application of hierarchy of reference genomes  
A method, computer product, and computer system of minimizing surprisal data comprising: at a source, reading and identifying characteristics of a genetic sequence of an organism; receiving an...
8855940 Method of detecting coliform bacteria from reflected light  
The present invention relates to a method of detecting coliform bacteria in water from reflected light, and also includes devices for the measurement, calculation and transmission of data relating...
8852912 Compositions and methods comprising alpha-amylase variants with altered properties  
Described are compositions and methods relating to variant alpha-amylases having altered biochemical properties and advantageous performance characteristics as compared to a reference...
8855939 System, method, and computer product for exon array analysis  
In one embodiment, a method for analyzing data generated by probe arrays is described that comprises receiving user selections of two or more data files and an identification of one or more subsets...
8855935 Method and system for displaying genetic and genealogical data  
A method and system for displaying genetic and genealogical data includes displaying indicators of related individuals. At least one genetically related individual is identified from a genetic...
8855937 Crop characteristic estimation  
A system for estimating a crop characteristic comprises a database, a plant growth model correlator, and a crop characteristic estimator. The database includes plant growth models for a plurality...
8855985 Method and system of obtaining improved data in perfusion measurements  
A method of deriving blood perfusion indices for a region of interest (ROI) of a subject, comprising the steps of administering a contrast agent to the subject during a dynamic imaging scan,...
8855936 Production of stable proteins  
The disclosure provides methods for designing and producing mutants that stabilize a protein. The folding energy of the protein and various mutants can be determined based on an equation comprising...
8849575 Methods, systems, and software for identifying functional biomolecules  
The present invention generally relates to methods of rapidly and efficiently searching biologically-related data space. More specifically, the invention includes methods of identifying...
8849576 Phylogenetic analysis of mass spectrometry or gene array data for the diagnosis of physiological conditions  
A universal data-mining platform is provided capable of analyzing mass spectrometry (MS) serum proteomic profiles and/or gene array data to produce biologically meaningful classification; i.e.,...
8849581 Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activity  
The methods described herein enable the evaluation of compounds on subjects to assess their therapeutic efficacy or toxic effects. The target of analysis is the underlying biochemical process or...
8849580 Uses of systems with degrees of freedom poised between fully quantum and fully classical states  
Disclosed herein are systems and uses of systems operating between fully quantum coherent and fully classical states. Such systems operate in what is termed the “Poised realm” and exhibit uni...
8849578 Computational method and apparatus for predicting polypeptide aggregation or solubility  
A prediction method for predicting the effect of an amino acid modification on the rate of aggregation (solubility) of a reference polypeptide comprising: calculating the difference in...
8849458 Collection device with selective display of test results, method and computer program product thereof  
A collection device with a selective display of test results and method thereof are disclosed. A structured collection procedure defining data collection times and the associated context of the...
8849579 Methods of detecting and monitoring cancer using 3D analysis of centromeres  
The present application relates to a method of detecting and monitoring cancer or precancer in a cell using three-dimensional analysis to assess centromere organization. In addition, the...
8849577 Methods of identifying biochemical pathways  
Methods for metabolomically determining the biological affects of compounds are described.
8843356 Computer systems and methods for associating genes with traits using cross species data  
A method for confirming the association of a query QTL or a query gene in the genome of a second species with a clinical trait T exhibited by the second species. A first QTL or a first gene in a...
8843325 Individual information determining method, individual information determining device, electronic apparatus, and individual information determining program  
Disclosed in an individual information determining method in which individual information of a subject is determined based on one or a plurality of pieces of biomolecule data collected from a...
8843320 Use of gene expression profiling to predict survival in cancer patient  
Gene expression profiling in multiple myeloma patients identifies genes that distinguish between patients with subsequent early death or long survival after treatment. Poor survival is linked to...
8843321 Methods and systems for processing glucose data measured from a person having diabetes  
Methods and systems are disclosed for estimating a glucose level of a person having diabetes comprises. One method may comprise: receiving into a computing device a plurality of measured glucose...
8835360 Combinatorial therapy for protein signaling diseases  
A method for selecting combinations of drugs for treatment of diseases that arise from deranged signaling pathways is disclosed. The method involves measuring the activity states for signaling...
8838394 Signal encoding and decoding in multiplexed biochemical assays  
This disclosure provides methods, systems, compositions, and kits for the multiplexed detection of a plurality of analytes in a sample. In some examples, this disclosure provides methods, systems,...
8838393 Systems and methods for topographic analysis  
The systems and methods described herein provide a scientific and analytical basis for the following: (a) collective interpretation of the entire spectrum of chromatographic data, e.g., GC×GC ...
8827917 Systems and methods for artifact detection in signals  
According to embodiments, a method and system for artifact detection in signals is disclosed. The artifacts may take the form of movement artifacts in physiological (e.g., pulse oximetry) signals....
8831887 Absolute PCR quantification  
The present application provides methods and devices for absolute quantification of polymerase chain reaction target nucleic acids. In particular, the methods and devices of the present application...
8831888 Method of processing spectrometric data  
A method of characterizing a sample from spectrometric data using calculation of spectral distance values is disclosed, for use in the field of mass spectrometry. Molecular formula assignment of...
8832655 Systems and methods for finding project-related information by clustering applications into related concept categories  
A system, method, and computer-readable medium, is described that finds similarities among programming applications based on semantic anchors found within the source code of such applications. The...
8831890 System and method for determining individualized medical intervention for a disease state  
A system and method for determining individualized medical intervention for a particular disease state, and especially for cancers, that includes the molecular profiling of a biological sample from...
8827942 Method for assessing a patients fluid status and/or sensitivity to fluid removal, controller, and devices  
The present invention relates to a method for assessing a patient's sensitivity to fluid removal from the patient's vascular system or to fluid replacement or addition with regard to the patient's...
8831893 Method for estimating kinetic rates  
The present invention relates to a method for estimation of kinetic characteristics for the formation and dissociation of a complex using lateral flow. The present invention facilitates an easy to...
8831924 Method and system for simulating surgical procedures  
A system and method for converting static/still medical images of a particular patient into dynamic and interactive images interacting with medical tools including medical devices by coupling a...
8831889 Quantification of differences between measured values and statistical validation based on the differences  
A system and method of validating differences between measured values of fluorescence intensities obtained from a fluorescence-based instrument, including: generating calibration histograms for...
8825412 Methods for non-invasive prenatal ploidy calling  
Methods for non-invasive prenatal ploidy calling are disclosed herein. Methods for determining the ploidy status of a chromosome in a gestating fetus from genotypic data measured from a sample of...
8825555 Privacy-sensitive sample analysis  
Processes are described for provision of privacy-sensitive sample analysis results to a sample provider. The sample provider generates a cryptographic commitment encoding a secret value, r, and a...
8825411 Design, synthesis and assembly of synthetic nucleic acids  
Methods of synthesizing oligonucleotides with high coupling efficiency (>99.5%) are provided. Methods for purification of synthetic oligonucleotides are also provided. Instrumentation...
8824770 Method for imaging and differential analysis of cells  
Provided are methods for determining and analyzing photometric and morphometric features of small objects, such as cells to, for example, identify different cell states. In particularly, methods...
8823519 Pasture management  
Systems, methods, and apparatuses for gathering data are disclosed. For example, a plant matter sensor includes a pair of parallel spaced apart sensor arms and a control console, a first of the...
8825568 Health care incident prediction  
Embodiments described herein relate to apparatuses and methods for incident prediction alerts for transmission to a health care organization system by applying rules to data sets. Each rule may...
8818734 Peptide ligands for sperm DNA fragmentation assay  
This invention comprises peptides, methods and a kit for identifying DNA fragmentation in non-viable sperm. Specific peptide sequences are claimed that bind to ssDNA and fragmented DNA.
8818782 System for developing patient specific therapies based on dynamic modeling of patient physiology and method thereof  
A system for developing patient-specific therapies based on dynamic modeling of patient-specific physiology and method thereof are disclosed. The system includes software modules configured to...
8818737 Methods, systems, algorithms and means for describing the possible conformations of actual and theoretical proteins and for evaluating actual and theoretical proteins with respect to folding, overall shape and structural motifs  
Methods, systems, algorithms and means for describing, analyzing and predicting protein folding motifs and other structures are provided. In one aspect, the Protein Folding Shape Code (PFSC)...
8818735 Methods for generating databases and databases for identifying polymorphic genetic markers  
Processes and methods for creating a database of genomic samples from healthy human donors, methods that use the database to identify and correlate polymorphic genetic markers and other markers...
8818732 Molecular network analysis support method and apparatus  
A molecular network analysis support method includes receiving designation of a biological phenomenon, extracting an interaction from a molecular network, and calculating a relation strength...
8818562 Simulated fermentation process  
A method of modeling a fermentation process comprises providing a first principles model of a fermentation process; determining the concentration of at least one substrate in a fermentation...
8818733 Determination of photodynamic therapy (PDT) treatment parameters  
A photodynamic therapy system and methods determine the amount (concentration) of a photosensitizer agent present in the target tissue. The system may also determine the tissue oxygenation. The...
8818731 Apparatus and method for interfacing time-variant signals  
An improved apparatus and method for interfacing a time variant waveform between two hardware environments. In one aspect, the invention comprises a circuit for accurately simulating the output of...