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8818734 Peptide ligands for sperm DNA fragmentation assay  
This invention comprises peptides, methods and a kit for identifying DNA fragmentation in non-viable sperm. Specific peptide sequences are claimed that bind to ssDNA and fragmented DNA.
8818782 System for developing patient specific therapies based on dynamic modeling of patient physiology and method thereof  
A system for developing patient-specific therapies based on dynamic modeling of patient-specific physiology and method thereof are disclosed. The system includes software modules configured to...
8818737 Methods, systems, algorithms and means for describing the possible conformations of actual and theoretical proteins and for evaluating actual and theoretical proteins with respect to folding, overall shape and structural motifs  
Methods, systems, algorithms and means for describing, analyzing and predicting protein folding motifs and other structures are provided. In one aspect, the Protein Folding Shape Code (PFSC)...
8818735 Methods for generating databases and databases for identifying polymorphic genetic markers  
Processes and methods for creating a database of genomic samples from healthy human donors, methods that use the database to identify and correlate polymorphic genetic markers and other markers...
8818732 Molecular network analysis support method and apparatus  
A molecular network analysis support method includes receiving designation of a biological phenomenon, extracting an interaction from a molecular network, and calculating a relation strength...
8818562 Simulated fermentation process  
A method of modeling a fermentation process comprises providing a first principles model of a fermentation process; determining the concentration of at least one substrate in a fermentation...
8818733 Determination of photodynamic therapy (PDT) treatment parameters  
A photodynamic therapy system and methods determine the amount (concentration) of a photosensitizer agent present in the target tissue. The system may also determine the tissue oxygenation. The...
8818731 Apparatus and method for interfacing time-variant signals  
An improved apparatus and method for interfacing a time variant waveform between two hardware environments. In one aspect, the invention comprises a circuit for accurately simulating the output of...
8812249 Analyzer apparatus and methods for lung disease  
An apparatus arranged to give an output indicative of lung disease state, in particular Chronic Obstructive Pulmonary Disease (COPD). The apparatus comprises a biomarker detection unit; a patient...
8812247 Method for achieving improved polypeptide expression  
The present invention relates to methods of optimization of a protein coding sequences for expression in a given host cell. The methods apply genetic algorithms to optimise single codon fitness...
8812240 Dose distribution modeling by region from functional imaging  
Functional imaging information is used to determine a probability of residual disease given a treatment. The functional imaging information shows different characteristic levels for different...
8812242 Melatonin suppression extent measuring device  
The present invention provides a melatonin suppression extent measuring device, which is able to receive and process a light signal to a spectral data, process the spectral data to a percent value...
8812239 Method and system for real-time analysis of biosensor data  
A method of biosensor-based detection of toxins includes the steps of providing a fluid to be analyzed having a plurality of photosynthetic organisms therein, wherein chemical, biological or...
8812244 Personalized wireless-based interactive diabetes treatment  
This is a system for integrating a system of education, monitoring and advising on glucose testing, diet, exercise and drug administration, by a wireless link, or GPRS system, using a device which...
8812246 Method and system for patient-specific modeling of blood flow  
Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a...
8812243 Transmission and compression of genetic data  
A method, computer product and computer system of transmitting a compressed genome of an organism: a computer at a source reading an uncompressed sequence and a reference genome from a repository;...
8812241 Method for normalizing clinical laboratory measurements  
A computerized method for normalizing the results of clinical laboratory tests to a reference scale includes providing a measured value of a clinically significant parameter, providing a set of...
8812258 Identifying a type of motion of an object  
An apparatus for identifying a type of motion and condition of a user is disclosed. One apparatus includes a motion detection sensor operative to generate an acceleration signature based on sensed...
8812245 Method and system for patient-specific modeling of blood flow  
Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a...
8805627 Method and system for organic specimen feature identification in ultrasound image  
A system, method, and computer program product. The system includes an ultrasound transducer configured for coupling ultrasound incident waves into selected regions of an organic specimen and...
8805621 Apparatus and method for comparing protein structure using 3D RDA and Fourier descriptor  
Provided is an apparatus and method for comparing a protein structure, which can search a protein similar to an inquiry protein in a 3D protein database in real time by describing a feature of a...
8805619 Tissue disorder imaging analysis  
Methods and systems are described for quantitatively determining a score for a patient having a disorder, e.g., a stroke, in a tissue, such as the brain, by analyzing both the extent and location...
8801652 Early stage peritonitis detection apparatus and methods  
The invention provides, inter alia, automated medical methods and apparatus that test PD effluent in a flow path (e.g., with an APD system or CAPD setup) to detect, for example, the onset of...
8805622 Field-based similarity search system and method  
A field-based similarity search system includes an input device which inputs a query molecule, and a processor which partitions a conformational space of the query molecule into a fragment graph...
8805618 Method and apparatus for monitoring offshore contamination  
The invention provides a method of detecting seawater contamination from an offshore hydrocarbon well facility comprising seabed wellheads connected by hydrocarbon conduits to a seabed pipeline...
8798939 Methods for designing, selecting and/or optimizing allosteric processing inhibitors for matrix metalloproteinases  
The present invention includes a crystal comprising a complex of the pro form of a matrix metalloprotease (proMMP) and a small-molecule allosteric processing inhibitor that inhibits that activation...
8798932 Frozen compositions and methods for piercing a substrate  
Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at...
8798979 Infusion device data set analyzer  
A system and method for evaluating drug data sets is provided. The system and method includes identifying when entries in a current data set differ from a data set comprising an aggregate of...
8798933 Frozen compositions and methods for piercing a substrate  
Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at...
8798936 Methods and systems for data analysis using the Burrows Wheeler transform  
The present disclosure provides computer implemented methods and systems for analyzing datasets, such as large data sets output from nucleic acid sequencing technologies. In particular, the present...
8795147 Modifying the genetic regulation of bone and cartilage cells and associated tissue by EMF stimulation fields and uses thereof  
An apparatus and method to modify the genetic regulation of mammalian tissue, bone, or any combination. The method may be comprised of the steps of tuning at least one predetermined profile...
8798934 Real time management of data relating to physiological control of glucose levels  
Continuous glucose monitoring (CGM) data and insulin delivery data are used to generate more reliable projected alarms related to a projected glucose levels. A memory stores endogenous data related...
8795170 Residual based monitoring of human health  
Improved human health monitoring is provided in the context of sensor measurements of typical vital signs and other biological parameters, by a system and method using an empirical model of the...
8798931 Evaluation method for evaluating a state of a photosynthesis sample  
An object of the present invention is to appropriately and easily evaluate a photosynthetic function of a photosynthetic sample contained in an evaluation sample. An evaluation method for...
8798935 Imaging method and use thereof  
The present invention relates to a method based on atomic force microscopy and the use thereof on biological surfaces. A method is provided to detect the Local Deviational Volume (LDV) of defined...
8798980 Molecular motor  
A molecular motor in which multiple concentric cylinders (or nested cones) rotate around a common longitudinal axis. Opposing complementary surfaces of the cylinders or cones are coated with...
8790890 Diagnostic method for connective tissue and its application  
The present invention relates to medicine and is used to evaluate conditions and to detect connective tissue pathology (and/or organ) by clonal analysis. The present invention relates to aesthetic...
8793074 Sequence covariance networks, methods and uses therefor  
Methods of identifying targets for designing a therapeutic agent are disclosed. These methods comprise: determining an amino acid sequence of one or more polypeptides of each isolate of a plurality...
8793073 Drug discovery methods  
Methods for identifying disease-related pathways that can be used to identify drug discovery targets, to identify new uses for known drugs, to identify markers for drug response, and related purposes.
8793078 Method for predicting activation energy using atomic fingerprint descriptor or atomic descriptor  
The present invention provides a method for constructing a database of atomic fingerprint descriptors. The invention provides a method for predicting activation energy using an atomic fingerprint...
8793075 Compositions and methods for therapeutic delivery with frozen particles  
Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at...
8788211 Method and system for comparing tissue ablation or abrasion data to data related to administration of a frozen particle composition  
Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at...
8788444 Data analysis method and system  
The present invention relates to the analysis of data to identify relationships between the input data and one or more conditions. One method of analyzing such data is by the use of neural networks...
8788214 Automated system for the comparison of individual genome, transcriptome, proteome, epigenome, and metabolome data with data from bonemarrow donor registers and blood banks, umbilical cord blood banks and tissue banks  
The invention relates to a system for the automatic, rapid and dynamic allocation of biological cells for transplantation, therapy, or research purposes between collection centers or banks (storage...
8786444 Systems and methods for determining signal quality of a physiological signal using a wavelet transform and an identified noise floor  
A method and system are provided for evaluating in patient monitoring whether a signal is sensed optimally by receiving a signal, transforming the signal using a wavelet transform, generating a...
8788215 Methods of associating an unknown biological specimen with a family  
The present invention provides a method of predicting whether an unknown biological specimen originates from a member of a particular family. The method compares DNA profiles from at least one...
8784307 Integrative biomechanical analysis  
The invention is a method and system for functional biomechanical analysis. The analysis assesses the biomechanical relationships of the spine and adjacent regions in a dynamic state based on a...
8788213 Laser mediated sectioning and transfer of cell colonies  
Disclosed herein are methods and devices for sectioning cell colonies. Also disclosed are methods of purifying cell colonies. A method of sectioning cell colonies can include providing a cell...
8788212 Compositions and methods for biological remodeling with frozen particle compositions  
Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at...
8781750 Cell-type-specific patterns of gene expression  
Among the methods, compositions, combinations and kits provided herein are those for determining gene expression levels in one or more cell types in heterogeneous cell samples, for identifying...