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7364674 |
Corneal implants produced by irradiation of polymer films
The corneal implant of the current invention takes the general form of a thin, transparent, flexible, porous, biocompatible film of suitable polymer material. The implant is sufficiently porous,...
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7347876 |
Method for expansion of epithelial stem cells
Transplantation of epithelial stem cells, cultured ex vivo on specifically treated amniotic membrane, yields, with that amniotic membrane, a surgical graft having expanded epithelial stem cells....
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RE38935 |
Intraocular lenses made from polymeric compositions and monomers useful in said compositions
Ophthalmic lenses, such as intraocular lenses, include crosslinked polymeric materials having a first constituent derived from a first monomeric component selected from the group consisting of...
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6976997 |
Artificial cornea
The invention provides implants suitable for use as an artificial cornea, and methods for making and using such implants. Artificial corneas having features of the invention may be two-phase...
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6875232 |
Corneal implant and method of manufacture
Prosthetic implants designed to be implanted in the cornea for modifying the cornea curvature and altering the corneal refractive power for correcting myopia, and myopia with astigmatism, such...
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6858033 |
Insertion system for intraocular lens
An insertion system for an intraocular lens having a deformable optical portion and loop-shaped support portions for supporting the optical portion within an eye includes a holding member for...
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6849090 |
Myopic corneal ring with central accommodating portion
A bio-compatible corneal ring for myopic correction and accommodation for presbyopia. The corneal ring is made from a bio-compatible material with a lens body having an inner and outer circular...
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6805712 |
Process for the production of polysiloxane-based polymeric compositions for use in medical devices
A process for producing polysiloxane prepolymers of improved homogeneity for use in the production of relatively high refractive index polymeric compositions is described herein. Polymeric...
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6723089 |
Device for the shaping of a substance on the surface of a cornea
A device for helping to correct imperfections of a cornea includes a molding lens. The molding lens includes an external surface having a concave shape to correspond to the desired shape of the...
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6689165 |
Surface modifications for enhanced epithelialization
A synthetic device for cornea augmentation and replacement that increases corneal epithelium cell adhesion and migration. Using tethered extracellular matrix proteins (ECMPs), corneal growth...
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6679605 |
Crystalline polymeric compositions for ophthalmic devices
Ophthalmic devices suitable for implantation into the eye through small incisions are disclosed. These devices are made from a composition comprising crystalline or semi-crystalline polymeric...
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6663668 |
Hydratable siloxane comprising porous polymers
An hydratable porous polymer comprising a polymerized polyorganosiloxane macromonomer of formula I Q—[M—L] c —M—Q (I) wherein c is in the range of from 0 to 5, preferably in the range of...
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6645715 |
Artificial cornea
The invention provides an in vitro avascular human corneal equivalent that comprises immortalized human cell lines. As these corneal equivalents are in vitro models, they are maintained in an...
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6544286 |
Pre-fabricated corneal tissue lens method of corneal overlay to correct vision
This invention relates to a contact lens made of donor corneal tissue, to a method of preparing that lens, and to a technique of placing the lens on the eye. The lens is made of donor corneal...
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6541572 |
Method of making high refractive index ophthalmic device materials
Disclosed is a two-step method of making soft, high refractive index, acrylic ophthalmic device materials. In the first step, a copolymer containing pendant oxirane groups is formed by...
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6271332 |
Polyurethanes made from polysiloxane/polyol macromers
The present invention describes a polymer and a precursor thereof; a prepolymer made essentially from a macromer that is cross-linked, for example, via its free hydroxy groups with a...
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6218360 |
Collagen based biomaterials and methods of preparation and use
This invention comprises purified native state Type VI collagen/βig, Type VI-βig collagen gel, including the crosslinked gel, and the use of the gel in fibrosis limited wound healing, and methods...
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5847023 |
Thermal irreversible gel corneal contact lens formed in situ
Balanced pH, thermo-irreversible gels comprising a polyoxyalkylene compound and an ionic polysaccharide are ideal materials for the formation of a protective contact lens over the cornea of the eye...
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5843185 |
Keratoprosthesis and method of corneal replacement
An improved keratoprosthesis, to be utilized to enhance a patient's vision, which includes an optical support segment structured to be disposed on an eyeball of the patient and containing an...
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5836313 |
Methods for making composite hydrogels for corneal prostheses
Methods for forming implantable composite keratoprostheses are provided. The methods provide keratoprostheses designed to provide a suitable substrate for corneal epithelial cell growth while...
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5713957 |
Corneal onlays
Corneal onlays for use in surgical implantation into or onto the cornea of a mammal are described. The corneal onlays according to the invention have an optical axis region with optical...
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5628793 |
Artificial lens
An artificial lens which specifically simulates the human eye in its mechanical properties. It is possible to produce the lens directly from a peptide mixture. The lens can be either homogeneous or...
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5433745 |
Corneal implants and methods for producing same
New corneal implants and methods for producing such implants are disclosed. The present corneal implants comprise a lens body which is optically clear and is structured to be surgically attached in...
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5376693 |
Thermo-irreversible gel corneal contact lens formed in situ
Balanced pH, thermo-irreversible gels comprising a polyoxyalkylene compound and an ionic polysaccharide are ideal materials for the formation of a protective contact lens over the cornea of the eye...
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5294314 |
Method of crosslinking amino acid containing polymers using photoactivatable chemical crosslinkers
A method for molecularly crosslinking amino acid containing polymers by photoactivating chemical crosslinkers which have been combined with the polymers. Collagen crosslinked by this method can be...
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5258024 |
Method of manufacture of a lens of transparent polymer having a modulated refractive index
The present invention relates to a method of manufacture of an optical lens providing refractive index modulation, characterized in that, starting from a lens of transparent hydrophilic polymer...
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5192316 |
Ocular device
An ocular device comprising a lens structure capable of being surgically associated with a living cornea to change the optical properties of the eye associated with the living cornea and an...
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5171318 |
Treated corneal prosthetic device
Prosthetic devices are prepared for subepithelial implantation by coating their surfaces with a coating comprising crosslinked or uncrosslinked fibronectin. If the surface of the device comprises a...
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5108428 |
Corneal implants and manufacture and use thereof
A corneal prosthesis including an optical element having an optically transparent central portion and an anterior surface capable of supporting a layer of epithelial cells, the optical element...
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5067961 |
Non-biodegradable two phase corneal implant and method for preparing same
The present invention provides a non-biodegradable corneal implant comprising (1) a polymerized transparent collagenous core having acylated amine or esterified carboxyl groups, and (2) a...
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4647282 |
Material for ocular prosthetics
An optical prosthetic device made from a material based on silicone compounds is a cured composition resulting from vulcanization of a mixture of...
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4607617 |
Apparatus and method for improving eyesight
The invention relates to an implant made of a polysulfone plastics material and designed to be implanted between the layers of the cornea to correct eyesight defects. The implant can as act as a...
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4581030 |
Collagen replacement prothesis for the cornea
This invention relates to a prosthetic replacement for the cornea and particularly to a transparent collagen material useful for making such a prosthesis and to methods for making such transparent...
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4563779 |
Corneal implant and method of making the same
A corneal implant and method of making the same utilizes a corneal plug removed from an eye, frozen solid, and centrally bored to, but not through, its Bowman's or its Descemet's membrane. An...
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4384374 |
Homotransplant for layer-by-layer keratoplasty
The homotransplant for lamellar or layer-by-layer keratoplasty is tendon tissue in the form of sections 50 to 300 microns thick. The employment of sections of tendon tissue as a homotransplant...
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