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8142886 |
Porous laser sintered articles
The present invention provides selectively laser sintered porous polymeric articles and methods of making and using the same. In one embodiment, a method of the present invention comprises...
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8137409 |
Method of installing a transcutaneous prosthesis
A method of installing a transcutaneous prosthesis which includes a first component, a second component adapted for location between the bone and the skin, the second component having a surface...
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8127770 |
Method of using an implant for treament of ligaments and tendons
A method of treating a ligament or tendon according to the present invention can include inserting a tissue-generating implant into the ligament or tendon to thereby treat the defect. The...
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8118877 |
Porous membranes for use with implantable devices
A membrane for implantation in soft tissue comprising a first domain that supports tissue ingrowth, disrupts contractile forces typically found in a foreign body response, encourages vascularity,...
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8110242 |
Methods of preparing hydrogel coatings
The present invention provides hydrogel coated, implantable medical devices and methods of coating hydrogels onto implantable medical devices. In one embodiment, a hydrogel coated medical device is...
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8106014 |
Methods and apparatus for enhanced growth of peripheral nerves and nervous tissue
A medical device comprises a tubular body having a lumen and a long axis; and a plurality of silk elements laid substantially parallel along the long axis of the lumen of the tubular body. A method...
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8067071 |
Composite self-cohered web materials
The present invention is directed to implantable bioabsorbable non-woven self-cohered web materials having a high degree of porosity. The web materials are very supple and soft, while exhibiting...
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8058067 |
Self-aligning tissue growth guide
The present invention relates to artificial tissue growth guides comprising a core and an outer sleeve, which facilitates the regeneration of damaged tissues, such as nerves. The core is fixed to...
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8048500 |
Composite self-cohered web materials
The present invention is directed to implantable bioabsorbable non-woven self-cohered web materials having a high degree of porosity. The web materials are very supple and soft, while exhibiting...
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8048503 |
Highly porous self-cohered web materials
The present invention is directed to implantable bioabsorbable non-woven self-cohered web materials having a high degree of porosity. The web materials are very supple and soft, while exhibiting...
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8002830 |
Surface directed cellular attachment
Implantable biomaterials, particularly hydrogel substrates with porous surfaces, and methods for enhancing the compatibility of biomaterials with living tissue, and for causing physical attachment...
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7985263 |
Membrane for use in sutured or sutureless surgical procedures
An improved, polymeric surgical membrane, which can be used in a variety of surgical procedures, such as sutured and sutureless duraplasty procedures. For sutureless applications, a textured,...
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7963997 |
Device for regeneration of articular cartilage and other tissue
An implantable device for facilitating the healing of voids in bone, cartilage and soft tissue is disclosed. A preferred embodiment includes a cartilage region comprising a polyelectrolytic complex...
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7927348 |
Stretch resistant coil device
A coil device is provided with a stretch resistant feature. The device includes a wound coil defining a lumen and a stretch resistant member at least partially received within the lumen. A...
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7901462 |
Implants with textured surface and methods for producing the same
Compositions and methods are provided for preparing a metal substrate having a uniform textured surface with a plurality of indentations with a diameter in the nanometer and micrometer range. The...
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7883526 |
Embolic coil having stretch resistant member with an attached end and an end with movement freedom
A coil device is provided with a stretch resistant feature. The device includes a wound coil defining a lumen and a stretch resistant member at least partially received within the lumen. A...
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7879109 |
Continuous phase composite for musculoskeletal repair
A composite material for positioning in the anatomy to form a selected function therein. The composite may be resorbable over a selected period of time. The composite may allow for selected bone...
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7875293 |
Biointerface membranes incorporating bioactive agents
A biointerface membrane for an implantable device including a nonresorbable solid portion with a plurality of interconnected cavities therein adapted to support tissue ingrowth in vivo, and a...
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7871440 |
Unitary surgical device and method
Unitary surgical devices (10) are disclosed. One group of the illustrated devices has a pair of biocompatible, bioresorbable anchors (16,18) connected to fixed lengths suture. The anchors (16,18)...
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7824699 |
Implantable prosthetic devices containing timed release therapeutic agents
Bioabsorbable drug delivery devices including modular drug delivery devices having shapes and sizes adapted to be inserted within a recess on the surface of an implantable prosthesis are disclosed....
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7815763 |
Porous membranes for medical implants and methods of manufacture
The present invention involves porous polymer membranes, suitable for use in medical implants, having controlled pore sizes, pore densities and mechanical properties. Methods of manufacturing such...
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7799563 |
Carrier fiber assembly for tissue structures
Methods and structures are disclosed where carrier fiber is used to enable the assembly of two and three dimensional structures of autologous tissue. Tissue is harvested from the donor, integrated...
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7772146 |
Artificial bone and joint compositions
The present invention provides a ceramic porous body for in-vitro and in-vivo use comprising a composition comprising a calcium aluminate (CA) containing phase and optionally at least one of an...
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7758654 |
Anti-adhesion device
The construct described herein allows opposing tissues to form adhesions with either side of the construct, as part of the natural healing process. The construct however is multi-layered, wherein...
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7749267 |
Expandable devices and methods for tissue expansion, regeneration and fixation
Expandable devices and methods for treating and enlarging a tissue, an organ or a cavity. The device is composed of a hollow expanding pouch made of a resorbable material or a perforated material...
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7722616 |
Use of a biological material containing three-dimensional scaffolds of hyaluronic acid derivatives for the preparation of implants in arthroscopy and kit for instruments for implanting said biological material by arthroscopy
The invention relates to use of a biological material containing cells supported on three-dimensional scaffolds containing at least one hyaluronic acid derivative for the preparation of grafts...
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7687138 |
Porous calcium phosphate ceramic and method for producing same
A porous calcium phosphate ceramic body comprising a substrate 1, and three-dimensional nanotunnel layers 2 formed on wall surfaces of the substrate 1, the three-dimensional nanotunnel layers 2...
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7682540 |
Method of making hydrogel implants
Implantable biomaterials, particularly hydrogel substrates with porous surfaces, and methods for enhancing the compatibility of biomaterials with living tissue, and for causing physical attachment...
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7659219 |
Highly porous self-cohered web materials having haemostatic properties
The present invention is directed to implantable bioabsorbable non-woven self-cohered web materials having a high degree of porosity. The web materials are very supple and soft, while exhibiting...
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7655288 |
Composite self-cohered web materials
The present invention is directed to implantable bioabsorbable non-woven self-cohered web materials having a high degree of porosity. The web materials are very supple and soft, while exhibiting...
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7641958 |
Membrane for use in sutured or sutureless surgical procedures
An improved, polymeric surgical membrane, which can be used in a variety of surgical procedures, such as sutured and sutureless duraplasty procedures. For sutureless applications, a textured,...
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7632228 |
Membrane for use with implantable devices
The present invention provides a biointerface membrane for use with an implantable device that interferes with the formation of a barrier cell layer including; a first domain distal to the...
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7622299 |
Bioengineered tissue substitutes
In one aspect, the invention provides methods for forming a target tissue substitute. The methods of the invention comprise the following steps: (a) providing a scaffold comprising one or more...
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7594934 |
Galactosidase-treated prosthetic devices
Matrix material for a substantially immunologically-compatible meniscal augmentation device of biocompatible and partially bioresorbable fibers is prepared by treatment with oc-galactosidase to...
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7569285 |
Enhanced bonding layers on titanium materials
The present invention provides a dense-coverage, adherent phosphorous-based coating on the native oxide surface of a material. Disclosed phosphorous-based coatings include phosphate and...
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7559953 |
Method for fixing tissue
A method of preparing a fixed biological tissue includes, shaping the biological tissue, cross-linking the biological tissue, sterilizing the biological tissue, and inactivating prions in the...
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RE40833 |
Medicinal product with a textile component
The present invention relates to a medicinal product with a textile component such as a wound compress having a surface containing a multiplicity of openings arranged in at least two hole patterns....
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7521231 |
Method for preparing engineered tissue
A method for preparing a human or animal tissue by applying a compressive force to a stack of sheets of living tissue thereby inducing adjacent layers to fuse or adhere to each other. The force is...
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7507483 |
Enhanced bonding layers on native oxide surfaces
An implantable device with a metal, metal alloy, metalloid, polymeric or ceramic surface and a phosphonic acid coating layer directly contacting the surface wherein the surface has hydroxyl groups...
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7445793 |
Support for tissue regeneration and process for producing the same
The present invention provides a scaffold in which cells can be stably retained and grafted in a uniform distribution state in the culture, preferable proliferation ability and viability can be...
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7410502 |
Medical prosthetic devices having improved biocompatibility
The invention relates to a medical prosthetic device having a metal material, such as titanium or an alloy thereof, where the surface parts of the metal material are coated with a layer of a...
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7407510 |
Orbital implant coating having differential degradation
A coating for an orbital implant where the coating has an anterior portion having a different, longer term bioabsorbability than a posterior portion. This allows the implant to have a smooth...
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7404819 |
Implantable prosthesis
An implantable prosthesis and a method of repairing an anatomical defect, such as a tissue or muscle wall defect, by promoting tissue growth thereto, while limiting the incidence of postoperative...
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7364592 |
Biointerface membrane with macro-and micro-architecture
Disclosed herein are biointerface membranes including a macro-architecture and a micro-architecture co-continuous with and bonded to and/or located within at least a portion of the...
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7347876 |
Method for expansion of epithelial stem cells
Transplantation of epithelial stem cells, cultured ex vivo on specifically treated amniotic membrane, yields, with that amniotic membrane, a surgical graft having expanded epithelial stem cells....
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7296998 |
Hydrophilic high density PTFE medical barrier
A medical barrier includes a sheet of unsintered substantially unexpanded hydrophilic polytetraflouroethylene (PTFE) polymer material having a density in a range of about 1.2 gm/cc to about 2.3...
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7208171 |
Injectable and bioadhesive polymeric hydrogels as well as related methods of enzymatic preparation
The invention is related to biomimetic gels that are prepared enzymatically, using a transglutaminase to cross-link polymer-peptide conjugates of rational design.
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7192450 |
Porous membranes for use with implantable devices
A membrane for implantation in soft tissue comprising a first domain that supports tissue ingrowth, disrupts contractile forces typically found in a foreign body response, encourages vascularity,...
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7163563 |
Unitary surgical device and method
Unitary surgical devices (10) are disclosed. One group of the illustrated devices has a pair of biocompatible, bioresorbable anchors (16,18) connected to fixed lengths suture. The anchors (16,18)...
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7147813 |
Neovascularization promoting membrane for bioimplants
A method of addressing a condition of a living body comprising the steps of using an energy beam to form a set of pores in a work piece biocompatible membrane. The pores should have a mean area of...
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