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8926710 Osteoinductive bone graft injectable cement  
Osteoconductive bone graft materials are provided. These compositions contain injectable cements and demineralized bone matrix fibers. The combination of these materials enables the filling of a...
8840677 Allograft bone plugs, systems and techniques  
The present invention provides a system, device, instruments and methods for inserting and/or improving the holding strength and purchase of a bone screw, bone pin, or bone dowel in bone....
8795361 Osteochondral plug graft, kit and method  
Each of an osteochondral plug graft and a kit comprises a trapezoid shaped construct configured for osteochondral implanting. An osteochondral regeneration method comprises forming a recipient...
8740987 Tissue-derived mesh for orthopedic regeneration  
An implant including a substantially cohesive aggregate comprising bone-derived particles. Cohesiveness is maintained by a member of mechanical interlocking, engagement of adjacent bone-derived...
8734525 Osteoinductive demineralized cancellous bone  
An osteoinductive demineralized bone matrix, corresponding osteoimplants, and methods for making the osteoinductive demineralized bone matrix are disclosed. The osteoinductive demineralized bone...
8702809 Demineralized cancellous bone scaffolds  
The present invention provides a cancellous bone scaffold to use in the replacement or repair of connective tissue such as ligaments and tendons. The cancellous bone scaffold has a fully...
8686064 Coupling agents for orthopedic biomaterials  
The invention provides a method for the preparation of bone-polymer composites wherein the mineral portion of the bone is treated with a coupling agent before being incorporated into a...
8673019 Use of anti-inflammatory compounds with allograft tissue implantation  
Methods and compositions are provided for reduction of inflammation and improved allograft/host tissue integration comprising placing at least one anti-inflammatory compound onto a site of the...
8652503 Bone paste  
A bone paste useful in the orthopedic arts, for example in the repair of non-union fractures, periodontal ridge augmentation, craniofacial surgery, implant fixation, impaction grafting, or any...
8609127 Medical implant with bioactive material and method of making the medical implant  
Embodiments of the invention include a medical device and a method of manufacturing a medical device having a porous scaffold in combination with a bioactive material. In some embodiments,...
8579986 Bone fusion material compressor and method of use  
The present invention provides an apparatus and method that will allow surgeons to produce bone growth masses for use in spinal surgery that are capable of maintaining their physical integrity...
8353967 Self-supporting collagen tunnel for guided tissue regeneration and method of using same  
A biocompatible, self-supporting, curved, collagen membrane adapted to be secured by bone tacks or bone screws over exposed bone at a desired bone graft site in the alveolar ridge of a patient...
8343229 Textured bone block implants  
Implantable pliable bone blocks comprising a solid block of cortical bone characterized by a length, width and thickness, having a first and a second face on opposite sides of the block. The first...
8328876 Bone matrix compositions and methods  
The present invention provides methods of improving the osteogenic and/or chondrogenic activity of a bone matrix, e.g., a dermineralized bone matrix (DBM), by exposing the bone matrix to one or...
8313742 Cell-containing bone graft material  
This invention relates to a musculoskeletogenic MSG graft composite made from whole bone marrow aspirate BMA having native levels of musculoskeletal progenitor cells MSPCs, comprising: a) a...
8241673 Method for producing biomaterials from bone tissue and material used for osteoplasty and tissue engineering  
A method for obtaining of biomaterials for osteoplasty and tissue engineering cleans a bone of natural origin, which is sawn to plates with a thickness of 0.2 to 2.0 cm, washed twice in 0.1 M...
8142502 Stable cartilage defect repair plug  
An apparatus and method of distributing a load to a cartilage defect repair plug is provided. A load is applied to a first articulation layer. The load is distributed to a second layer and the...
8092529 Meniscus regeneration device  
Methods and devices are provided for regenerating a meniscus. The devices comprise a layer of toughened naturally occurring extracellular matrix. The devices may, optionally, further comprise a...
8012205 Cartilage repair and regeneration device  
A cartilage repair device comprises a scaffold, for example a naturally occurring extracellular matrix material, and a biological lubricant. The biological lubricant is applied to the naturally...
7981156 Bone grafts  
Spinal spacers 20 are provided for fusion of a motion segment. The spacers include a load bearing member 21 having a wall 22 sized for engagement within a space between adjacent vertebrae to...
7976861 Irradiated implantable bone material  
A method for making an implantable bone material. The method includes providing a bone composition consisting essentially of demineralized human bone, and irradiating the composition at a...
7959683 Packed demineralized cancellous tissue forms for disc nucleus augmentation, restoration, or replacement and methods of implantation  
A composition for spinal disc repair comprising a plurality of uniformly shaped demineralized cancellous bone pieces ranging in size from about 2.0 mm to about 4.0 mm loaded into a porous mesh...
7931692 Implant derived from bone  
An implant which is particularly suitable for the repair and/or replacement of a skeletal joint, e.g., a vertebral joint, includes a unit of monolithic bone possessing at least one demineralized...
7837740 Two piece cancellous construct for cartilage repair  
The invention is directed toward a cartilage repair assembly comprising a shaped allograft two piece construct with a demineralized cancellous cap and a mineralized cylindrical base member...
7824702 Composition for making a bone paste  
Disclosed herein is an efficient and cost-effective system for reconstituting bone pastes comprising a first syringe containing a reconstitution fluid and second syringe containing paste...
7819918 Implantable tissue repair device  
An implantable tissue repair device has a cover and tissue regeneration material. The cover includes a top panel and a bottom panel joined together along a leading edge. The tissue regeneration...
7758643 Stable cartilage defect repair plug  
A method of distributing a load to a cartilage defect repair plug is provided. A load is applied to a first articulation layer. The load is distributed to a second layer and the load is...
7753963 Demineralized bone-derived implants  
Selectively demineralized bone-derived implants are provided. In one embodiment, a bone sheet for implantation includes a demineralized field surrounding mineralized regions. In another...
7749555 Modification of chemical forces of bone constructs  
The present invention relates to a method for enhancing ingrowth of host bone comprising: modifying a bone graft structure to provide an ionic gradient to produce a modified bone graft structure;...
7678385 Irradiated implantable bone material  
A method for making an implantable bone material. The method includes providing a bone composition consisting essentially of demineralized human bone, and irradiating the composition at a...
7670384 Bone graft composition comprising a bone material and a carrier comprising denatured demineralized bone  
Formed compositions for application to a bone surface of a human or animal subject, comprising: a bone material; and a carrier comprising denatured demineralized bone, where the composition is...
7662184 Osteoimplant and method for making same  
A method of manufacturing an osteoinductive osteoimplant is provided which comprises the steps of: demineralizing part or all of at least one surface of a monolithic section of cortical bone to a...
7658768 Bone graft substitute composition  
Bone graft substitute compositions and methods of making the compositions are disclosed. In some embodiments, a method of making a composition includes contacting a mixing solution with a first...
7621963 Composite bone graft material  
A bone graft material comprising about 50-90% quickly bioresorbable porogen particles and about 10-50% of a calcium matrix material. A bioactive substance can be included in the matrix material,...
7608113 Demineralized bone implants  
Selectively demineralized bone-derived implants are provided. In one embodiment, a bone sheet for implantation includes a demineralized field surrounding mineralized regions. In another...
7550007 Osteochondral allografts  
Provided are procedures and instruments for preparing and transplanting osteochondral allograft plugs to a host bone to repair an articular cartilage defect. An allograft bone plug having a...
7537617 Bone strip implants and method of making same  
The present invention provides an implant for use in fusing adjacent bony structures. The implant comprises a plurality of bone pieces formed into at least one load bearing layer.
7530982 Composite allograft formation instrument  
A graft formation and delivery instrument comprising an outer barrel, a piston, and an inner pin. The outer barrel has a center aperture. The piston is seated within the center aperture, has a...
7507254 Inorganic bone graft materials using animal bone and method for preparing thereof  
The present invention relates to inorganic bone graft materials and a method for preparing the bone graft materials. Particularly, the present invention relates to a method for preparing bone...
7494950 Bone cement compositions having fiber-reinforcement and/or increased flowability  
The present invention relates in general to implantable compositions, and method for preparing same, containing a calcium salt-containing component, optionally demineralized bone, a plurality of...
7488348 Cartilage allograft plug  
The invention is directed toward a cartilage repair assembly comprising a cylindrically shaped allograft structure of subchondral bone with an integral overlying smaller diameter cartilage cap...
7462200 Method for tissue grafting  
The present invention provides a method for tissue grafting. The method includes obtaining tissue harvested from an individual, obtaining allograft material, placing the allograft material in a...
7459018 Injectable calcium phosphate cement  
A calcium phosphate composition comprising at least one calcium phosphate mineral, at least one reaction retarding agent, at least one biding agent, and at least one sodium phosphate compound.
7427293 Osteochondral plug graft, kit and method  
Each of an osteochondral plug graft and a kit comprises a trapezoid shaped construct configured for osteochondral implanting. An osteochondral regeneration method comprises forming a recipient...
7371408 Bone graft substitute composition  
A bone graft substitute composition comprising calcium sulfate; a mixing solution selected from the group consisting of sterile water, sodium chloride, phosphate buffered saline, potassium...
7368065 Implants with textured surface and methods for producing the same  
Compositions and methods are provided for preparing a metal substrate having a uniform textured surface with a plurality of indentations with a diameter in the nanometer and micrometer range. The...
7361195 Cartilage repair apparatus and method  
An orthopaedic device for repairing and regenerating cartilage includes a plug configured to be positioned in a hole formed in the cartilage and an anchor configured to support the plug. One or...
7351262 Bone implants and methods of making same  
The present invention provides an implant for use in fusing adjacent bony structures. The implant comprises a plurality of pieces of bone and a flexible mechanism including one or more flexible,...
7162850 Method of packaging a bone allograft intended for a spinal fusion procedure  
A system and method of packaging a bone allograft for use in a future medical procedure in which the bone allograft is stored in a saturated saline solution in an airtight container. The saline...
7141072 Method for promoting regeneration of surface cartilage in a damaged joint using multi-layer covering  
A method of promoting regeneration of surface cartilage of a joint includes the steps of covering the area to be treated with a patch which includes a sheet of collagen membrane material. The...

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